JohnF.KuemmerleMD

Gastroenterology • Richmond, VA

Professor, Internal Medicine, Virginia Commonwealth University, Medical College of Virginia School of Medicine

Join to view full profile

Dr. Kuemmerle is on Doximity

As a Doximity member you'll join over two million verified healthcare professionals in a private, secure network.

Connect with other colleagues in the same hospital or clinic
Search all U.S. specialist profiles and refer a patient
Read the latest clinical news and earn CME/CEU credits

See Dr. Kuemmerle's full profile

Already have an account?

Office
1602 Skipwith Rd
Richmond, VA 23229
Is this information wrong?

Education & Training

Virginia Commonwealth University Health SystemFellowship, Gastroenterology, 1990 - 1993
Virginia Commonwealth University Health SystemResidency, Internal Medicine, 1987 - 1990
Ohio Valley Medical CenterInternship, Transitional Year, 1984 - 1985
Eastern Virginia Medical SchoolClass of 1984

Certifications & Licensure

VA State Medical License 1987 - 2024
American Board of Internal Medicine Gastroenterology

Publications & Presentations

PubMed

7 citations
The Pathogenesis and Clinical Management of Stricturing Crohn Disease.
Christopher J. Schmoyer, Jakob Saidman, Jaime L Bohl, Claire L Bierly, John F. Kuemmerle, Stephen J. Bickston> ;Inflammatory Bowel Diseases. 2021 Oct 20
15 citations
Whole-genome sequencing of African Americans implicates differential genetic architecture in inflammatory bowel disease.
Hari K. Somineni, Sini Nagpal, Suresh Venkateswaran, David J. Cutler, David T. Okou, Talin Haritunians, Claire L. Simpson, Ferdouse Begum, Lisa W. Datta, Antonio Quiro...> ;American Journal of Human Genetics. 2021 Mar 4
18 citations
The fate of myofibroblasts during the development of fibrosis in Crohn's disease.
Chao Li, John F. Kuemmerle> ;Journal of Digestive Diseases. 2020 Jun 1
22 citations
Endoplasmic Reticulum Stress in Subepithelial Myofibroblasts Increases the TGF-β1 Activity That Regulates Fibrosis in Crohn's Disease.
Chao Li, John R. Grider, Karnam S. Murthy, Jaime L. Bohl, Emily Rivet, Nicole E. Wieghard, John F. Kuemmerle> ;Inflammatory Bowel Diseases. 2020 May 12
94 citations
Genome-Wide Association Study Identifies African-Specific Susceptibility Loci in African Americans With Inflammatory Bowel Disease
Steven R. Brant, David T. Okou, Claire L. Simpson, David J. Cutler, Talin Haritunians, Jonathan P. Bradfield, Pankaj Chopra, Jarod Prince, Ferdouse Begum, Archana Kuma...> ;Gastroenterology. 2017 Jan 1
5 citations
Genetic and epigenetic regulation of intestinal fibrosis
Chao Li, John F. Kuemmerle> ;United European Gastroenterology Journal. 2016 Jul 14
6 citations
Timing of Last Preoperative Dose of Infliximab Does Not Increase Postoperative Complications in Inflammatory Bowel Disease Patients
Anas Alsaleh, Jill K. J. Gaidos, Le Kang, John F. Kuemmerle> ;Digestive Diseases and Sciences. 2016 Apr 28
57 citations
Nonmuscle Myosin IIA Regulates Intestinal Epithelial Barrier in vivo and Plays a Protective Role During Experimental Colitis.
Nayden G. Naydenov, Alex Feygin, Dongdong Wang, John F. Kuemmerle, Gianni Harris, Mary Anne Conti, Robert S. Adelstein, Andrei I. Ivanov> ;Scientific Reports. 2016 Apr 11
31 citations
Actin-Depolymerizing Factor and Cofilin-1 Have Unique and Overlapping Functions in Regulating Intestinal Epithelial Junctions and Mucosal Inflammation
Dongdong Wang, Nayden G. Naydenov, Alex Feygin, Somesh Baranwal, John F. Kuemmerle, Andrei I. Ivanov> ;The American Journal of Pathology. 2016 Apr 1
1 citations
Murine Trinitrobenzoic Acid-Induced Colitis as a Model of Crohn's Disease
John F. Kuemmerle> ;Methods in Molecular Biology. 2016 Jan 1
14 citations
Increased IGF-IEc expression and mechano-growth factor production in intestinal muscle of fibrostenotic Crohn's disease and smooth muscle hypertrophy
Chao Li, Kent Vu, Krystina B. Hazelgrove, John F. Kuemmerle> ;American Journal of Physiology. Gastrointestinal and Liver Physiology. 2015 Dec 1
54 citations
Characterization of Genetic Loci That Affect Susceptibility to Inflammatory Bowel Diseases in African Americans
Chengrui Huang, Talin Haritunians, David T. Okou, David J. Cutler, Michael E. Zwick, Kent D. Taylor, Lisa W. Datta, Joseph C. Maranville, Zhenqiu Liu, Shannon E. Ellis...> ;Gastroenterology. 2015 Nov 1
80 citations
Noncanonical STAT3 Activation Regulates Excess TGF-β1 and Collagen I Expression in Muscle of Stricturing Crohn’s Disease
Chao Li, Audra Iness, Jennifer Yoon, John R. Grider, Karnam S. Murthy, John M. Kellum, John F. Kuemmerle> ;Journal of Immunology. 2015 Apr 1
39 citations
Activation of the umami taste receptor (T1R1/T1R3) initiates the peristaltic reflex and pellet propulsion in the distal colon
Derek M. Kendig, Norman Hurst, Zachary L. Bradley, Sunila Mahavadi, John F. Kuemmerle, Vijay Lyall, John A. DeSimone, Karnam S. Murthy, John R. Grider> ;American Journal of Physiology. Gastrointestinal and Liver Physiology. 2014 Dec 1
27 citations
Loss of γ-cytoplasmic actin triggers myofibroblast transition of human epithelial cells
Susana Lechuga, Somesh Baranwal, Chao Li, Nayden G. Naydenov, John F. Kuemmerle, Vera Dugina, Christine Chaponnier, Andrei I. Ivanov> ;Molecular Biology of the Cell. 2014 Oct 15
9 citations
Cytokine-induced iNOS and ERK1/2 inhibit adenylyl cyclase type 5/6 activity and stimulate phosphodiesterase 4D5 activity in intestinal longitudinal smooth muscle
Sunila Mahavadi, Ancy D. Nalli, Divya P. Kumar, Wenhui Hu, John F. Kuemmerle, John R. Grider, Karnam S. Murthy> ;American Journal of Physiology. Cell Physiology. 2014 Aug 15
6 citations
ABIM Maintenance of Certification 2014: Navigating the Challenges to Find Opportunities for Success
John F. Kuemmerle> ;Gastroenterology. 2014 Aug 1
86 citations
Mechanisms that mediate the development of fibrosis in patients with Crohn's disease.
Chao Li, John F. Kuemmerle> ;Inflammatory Bowel Diseases. 2014 Jul 1
18 citations
Hypercontractility of Intestinal Longitudinal Smooth Muscle Induced by Cytokines Is Mediated by the Nuclear Factor-κB/AMP-Activated Kinase/Myosin Light Chain Kinase Pa...
Ancy D. Nalli, Divya P. Kumar, Sunila Mahavadi, Othman Al-Shboul, Reem Alkahtani, John F. Kuemmerle, John R. Grider, Karnam S. Murthy> ;The Journal of Pharmacology and Experimental Therapeutics. 2014 Jul 1
8 citations
Jun kinase-induced overexpression of leukemia-associated Rho GEF (LARG) mediates sustained hypercontraction of longitudinal smooth muscle in inflammation
Othman Al-Shboul, Ancy D. Nalli, Divya P. Kumar, Ruizhe Zhou, Sunila Mahavadi, John F. Kuemmerle, John R. Grider, Karnam S. Murthy> ;American Journal of Physiology. Cell Physiology. 2014 Jun 15
23 citations
Regulation of Gβγi-dependent PLC-β3 activity in smooth muscle: inhibitory phosphorylation of PLC-β3 by PKA and PKG and stimulatory phosphorylation of Gαi-GTPase-activa...
Ancy D. Nalli, Divya P. Kumar, Othman Al-Shboul, Sunila Mahavadi, John F. Kuemmerle, John R. Grider, Karnam S. Murthy> ;Cell Biochemistry and Biophysics. 2014 Apr 29
46 citations
Increased activation of latent TGF-β1 by αVβ3 in human Crohn's disease and fibrosis in TNBS colitis can be prevented by cilengitide.
Chao Li, Robert S. Flynn, John R. Grider, Karnam S. Murthy, John M. Kellum, Homayoon Akbari, John F. Kuemmerle> ;Inflammatory Bowel Diseases. 2013 Dec 1
2 citations
Effective Use of Technology in Gastroenterology Training
John F. Kuemmerle> ;Gastroenterology. 2012 Oct 1
43 citations
Insulin-Like Growth Factors in the Gastrointestinal Tract and Liver
John F. Kuemmerle> ;Endocrinology and Metabolism Clinics of North America. 2012 Jun 1
38 citations
Up-regulation of brain-derived neurotrophic factor in primary afferent pathway regulates colon-to-bladder cross-sensitization in rat
Chunmei Xia, Melisa Gulick, Sharon J Yu, John R. Grider, Karnam S. Murthy, John F. Kuemmerle, Hamid I. Akbarali, Li-Ya Qiao> ;Journal of Neuroinflammation. 2012 Feb 15
Join now to see all

Hospital Affiliations

VCU Medical CenterRichmond, Virginia
Sentara Norfolk General HospitalNorfolk, Virginia
Henrico Doctors' HospitalHenrico, Virginia
Parham Doctors' HospitalHenrico, Virginia