JohnR.LambMD

PubMed

• 9 citations
  Limits and potential of combined folding and docking.
  Gabriele Pozzati, Wensi Zhu, Claudio Bassot, John Lamb, Petras J. Kundrotas, Arne Elofsson> ;Bioinformatics. 2021 Nov 12
• 1 citations
  The evolutionary history of topological variations in the CPA/AT transporters.
  Govindarajan Sudha, Claudio Bassot, John Lamb, Nanjiang Shu, Yan Huang, Arne Elofsson> ;Plos Computational Biology. 2021 Aug 17
• 5 citations
  pyconsFold: a fast and easy tool for modelling and docking using distance predictions.
  John Lamb, Arne Elofsson> ;Bioinformatics. 2021 Jul 8
• 17 citations
  Serum levels of ACE2 are higher in patients with obesity and diabetes
  Valur Emilsson, Elias F. Gudmundsson, Thor Aspelund, Brynjolfur G. Jonsson, Alexander Gudjonsson, Lenore J. Launer, John Lamb, Valborg Gudmundsdottir, Lori L. Jennings...> ;Obesity Science & Practice. 2021 Apr 1
• 14 citations
  It's in Our Blood: A Glimpse of Personalized Medicine.
  John Lamb, Lori L. Jennings, Valborg Gudmundsdottir, Vilmundur Gudnason, Valur Emilsson> ;Trends in Molecular Medicine. 2021 Jan 1
• 19 citations
  ACE2 levels are altered in comorbidities linked to severe outcome in COVID-19
  Valur Emilsson, Elias F. Gudmundsson, Thor Aspelund, Brynjolfur G. Jonsson, Alexander Gudjonsson, Lenore J. Launer, John Lamb, Valborg Gudmundsdottir, Lori L. Jennings...> ;Medrxiv. 2020 Jun 5
• 50 citations
  Circulating Protein Signatures and Causal Candidates for Type 2 Diabetes
  Valborg Gudmundsdottir, Shaza B. Zaghlool, Valur Emilsson, Thor Aspelund, Marjan Ilkov, Elias F. Gudmundsson, Stefan M Jonsson, Nuno R. Zilhão, John Lamb, Karsten Suhr...> ;Diabetes. 2020 May 8
• 11 citations
  Tau overexpression exacerbates neuropathology after repeated mild head impacts in male mice.
  Hank Cheng, Lisa M. Deaton, Minhua Qiu, Sukwon Ha, Reynand Pacoma, Jianmin Lao, Valerie Tolley, Rita Moran, Amber Keeton, John Lamb, John Fathman, John R. Walker, Andr...> ;Neurobiology of Disease. 2020 Feb 1
• 141 citations
  DisProt: intrinsic protein disorder annotation in 2020.
  András Hatos, Borbála Hajdu-Soltész, Alexander Miguel Monzon, Nicolas Palopoli, Lucía Álvarez, Burcu Aykac-Fas, Claudio Bassot, Guillermo Ignacio Benitez, Martina Bevi...> ;Nucleic Acids Research. 2019 Nov 12
• 11 citations
  PconsFam : An Interactive Database of Structure Predictions of Pfam Families
  John Lamb, Aleksandra I. Jarmolinska, Mirco Michel, David Menéndez-Hurtado, Joanna I. Sulkowska, Arne Elofsson> ;Journal of Molecular Biology. 2019 Jun 14
• 48 citations
  Guide Swap enables genome-scale pooled CRISPR-Cas9 screening in human primary cells.
  Pamela Y. Ting, Albert E. Parker, J. Scott Lee, Chris Trussell, Orzala Sharif, Fabio Luna, Glenn C. Federe, S. Whitney Barnes, John R. Walker, Julie Vance, Mu-Yun Gao,...> ;Nature Methods. 2018 Oct 8
• 275 citations
  Co-regulatory networks of human serum proteins link genetics to disease
  Valur Emilsson, Marjan Ilkov, John Lamb, Nancy Finkel, Elias F. Gudmundsson, Rebecca Pitts, Heather Hoover, Valborg Gudmundsdottir, Shane R. Horman, Thor Aspelund, Le ...> ;Science. 2018 Aug 24
• 20 citations
  Topology of membrane proteins-predictions, limitations and variations.
  Konstantinos D. Tsirigos, Sudha Govindarajan, Claudio Bassot, Åke Västermark, John Lamb, Nanjiang Shu, Arne Elofsson> ;Current Opinion in Structural Biology. 2018 Jun 1
• 56 citations
  Induction of muscle stem cell quiescence by the secreted niche factor Oncostatin M
  Srinath C. Sampath, Srihari C. Sampath, Andrew Tri Van Ho, Stéphane Y. Corbel, Joshua D. Millstone, John Lamb, John R. Walker, Bernd Kinzel, Christian Schmedt, Helen M...> ;Nature Communications. 2018 Apr 18
• 25 citations
  Functional profiling of microtumors to identify cancer associated fibroblast-derived drug targets
  Shane R. Horman, Jeremy To, John Lamb, Jocelyn Zoll, Nicole Leonetti, Buu Tu, Rita Moran, Robbin Newlin, John R. Walker, Anthony P. Orth> ;Oncotarget. 2017 Oct 20
• 141 citations
  Inhibition of DYRK1A and GSK3B induces human β-cell proliferation.
  Weijun Shen, Brandon Taylor, Qihui Jin, Van Nguyen-Tran, Shelly Meeusen, You-Qing Zhang, Anwesh Kamireddy, Austin De Swafford, Andrew F. Powers, John P Walker, John La...> ;Nature Communications. 2015 Oct 26
• 118 citations
  Common dysregulation network in the human prefrontal cortex underlies two neurodegenerative diseases
  Manikandan Narayanan, Jimmy L. Huynh, Kai Wang, Xia Yang, Seungyeul Yoo, Joshua McElwee, Bin Zhang, Chunsheng Zhang, John Lamb, Tao Xie, Christine Suver, Cliona Molony...> ;Molecular Systems Biology. 2014 Jul 1
• 163 citations
  In vivo discovery of immunotherapy targets in the tumour microenvironment
  Penghui Zhou, Donald R. Shaffer, Diana A. Alvarez Arias, Yukoh Nakazaki, Wouter Pos, Alexis J. Torres, Viviana Cremasco, Stephanie K. Dougan, Glenn S. Cowley, Kutlu G....> ;Nature. 2014 Feb 6
• 30 citations
  Development of a Colon Cancer GEMM-Derived Orthotopic Transplant Model for Drug Discovery and Validation
  Eric S. Martin, Peter J. Belmont, Mark J. Sinnamon, Larissa Georgeon Richard, Jing Yuan, Erin M. Coffee, Jatin Roper, Lydia Lee, Pedram Heidari, Sophia Y. Lunt, Gautam...> ;Clinical Cancer Research. 2013 Jun 1
• 1148 citations
  Integrated Systems Approach Identifies Genetic Nodes and Networks in Late-Onset Alzheimer’s Disease
  Bin Zhang, Chris Gaiteri, Liviu-Gabriel Bodea, Zhi Wang, Joshua J McElwee, Alexei A. Podtelezhnikov, Chunsheng Zhang, Tao Xie, Linh M. Tran, Radu Dobrin, Eugene M. Flu...> ;Cell. 2013 Apr 25
• 68 citations
  A comprehensive characterization of genome-wide copy number aberrations in colorectal cancer reveals novel oncogenes and patterns of alterations.
  Tao Xie, Giovanni d’ Ario, John Lamb, Eric S. Martin, Kai Wang, Sabine Tejpar, Mauro Delorenzi, Fred T. Bosman, Arnaud Roth, Pu Yan, Stéphanie Bougel, Antonio Fabio Di...> ;Plos One. 2012 Jul 31
• 108 citations
  Systems analysis of eleven rodent disease models reveals an inflammatome signature and key drivers
  I-Ming Wang, Bin Zhang, Xia Yang, Jun Zhu, Serguei Stepaniants, Chunsheng Zhang, Qingying Meng, Mette A. Peters, Yudong D. He, Chester Ni, Deborah Slipetz, Michael A. ...> ;Molecular Systems Biology. 2012 Jan 1
• 8 citations
  Clinicopathologic and gene expression parameters predict liver cancer prognosis
  Ke Hao, John Lamb, Chunsheng Zhang, Tao Xie, Kai Wang, Bin Zhang, Eugene Chudin, Nikki P. Lee, Mao Mao, Hua Zhong, Danielle M. Greenawalt, Mark D. Ferguson, Irene Oi-L...> ;BMC Cancer. 2011 Nov 9
• 47 citations
  Inferring causal genomic alterations in breast cancer using gene expression data
  Linh M Tran, Bin Zhang, Zhan Zhang, Chunsheng Zhang, Tao Xie, John Lamb, Hongyue Dai, Eric E. Schadt, Jun Zhu> ;BMC Systems Biology. 2011 Aug 1
• 54 citations
  Predictive genes in adjacent normal tissue are preferentially altered by sCNV during tumorigenesis in liver cancer and may rate limiting
  John Lamb, Chunsheng Zhang, Tao Xie, Kai Wang, Bin Zhang, Ke Hao, Eugene Chudin, Hunter B. Fraser, Joshua Millstein, Mark D. Ferguson, Christine Suver, Irena Ivanovska...> ;Plos One. 2011 Jul 5
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