JohnJLehmanJr.MD

PubMed

• 11 citations
  Chronic caloric restriction attenuates a loss of sulfatide content in PGC-1α mouse cortex: a potential lipidomic role of PGC-1α in neurodegeneration
  Michael A. Kiebish, Dee M. Young, John J. Lehman, Xianlin Han> ;Journal of Lipid Research. 2012 Feb 1
• 158 citations
  PGC-1α and ERRα target gene downregulation is a signature of the failing human heart
  Smita Sihag, Sharon Cresci, Allie Y. Li, Carmen C. Sucharov, John J. Lehman> ;Journal of Molecular and Cellular Cardiology. 2009 Feb 1
• 132 citations
  The Transcriptional Coactivator PGC-1α is Essential for Maximal and Efficient Cardiac Mitochondrial Fatty Acid Oxidation and Lipid Homeostasis
  John J. Lehman, Sihem Boudina, Natasha H. Banke, Nandakumar Sambandam, Xianlin Han, Deanna M. Young, Teresa C. Leone, Richard W. Gross, E. Douglas Lewandowski, E. Dale...> ;American Journal of Physiology. Heart and Circulatory Physiology. 2008 May 16
• 185 citations
  A Role for the Transcriptional Coactivator PGC-1α in Muscle Refueling *
  Adam R. Wende, Paul J. Schaeffer, Glendon J. Parker, Christoph Peter Gerhard Zechner, Dong Ho Han, May M. Chen, Chad R. Hancock, John J. Lehman, Janice M. Huss, Donald...> ;The Journal of Biological Chemistry. 2007 Dec 14
• 49 citations
  Dramatic Accumulation of Triglycerides and Precipitation of Cardiac Hemodynamic Dysfunction during Brief Caloric Restriction in Transgenic Myocardium Expressing Human ...
  David J. Mancuso, Xianlin Han, Christopher M. Jenkins, John J. Lehman, Nandakumar Sambandam, Harold F. Sims, Jingyue Yang, Wei Yan, Kui Yang, Karen G. Green, Dana R. A...> ;The Journal of Biological Chemistry. 2007 Mar 23
• 747 citations
  PGC-1alpha deficiency causes multi-system energy metabolic derangements: muscle dysfunction, abnormal weight control and hepatic steatosis.
  Teresa C. Leone, John J. Lehman, Brian N. Finck, Paul J. Schaeffer, Adam R. Wende, Sihem Boudina, Michael Courtois, David F. Wozniak, Nandakumar Sambandam, Carlos Bern...> ;Plos Biology. 2005 Mar 15
• 315 citations
  Cardiac-Specific Induction of the Transcriptional Coactivator Peroxisome Proliferator-Activated Receptor γ Coactivator-1α Promotes Mitochondrial Biogenesis and Reversi...
  Laurie K. Russell, Carolyn M. Mansfield, John J. Lehman, Attila Kovacs, Michael Courtois, Jeffrey E. Saffitz, Denis M. Medeiros, Maria L. Valencik, John Alan McDonald,...> ;Circulation Research. 2004 Mar 5
• 210 citations
  Transcriptional activation of energy metabolic switches in the developing and hypertrophied heart.
  John J. Lehman, Daniel P. Kelly> ;Clinical and Experimental Pharmacology & Physiology. 2002 Apr 1
• 131 citations
  Gene regulatory mechanisms governing energy metabolism during cardiac hypertrophic growth.
  John J. Lehman, Daniel P. Kelly> ;Heart Failure Reviews. 2002 Apr 1
• Regulatory networks controlling mitochondrial energy production in the developing, hypertrophied, and diabetic heart.
  Finck BN, Lehman JJ, Barger PM, Kelly DP> ;Cold Spring Harb. Symp. Quant. Biol.. 2002-01-01
• 736 citations
  The cardiac phenotype induced by PPARα overexpression mimics that caused by diabetes mellitus
  Brian N. Finck, John J. Lehman, Teresa C. Leone, Michael J. Welch, Michael J. Bennett, Attila Kovacs, Xianlin Han, Richard W. Gross, Ray Kozak, Gary D. Lopaschuk, Dani...> ;The Journal of Clinical Investigation. 2002 Jan 1
• 488 citations
  Restoration of insulin-sensitive glucose transporter (GLUT4) gene expression in muscle cells by the transcriptional coactivator PGC-1
  Laura F. Michael, Zhidan Wu, R. Bentley Cheatham, Pere Puigserver, Guillaume Adelmant, John J. Lehman, Daniel P. Kelly, Bruce M. Spiegelman> ;Proceedings of the National Academy of Sciences of the United States of America. 2001 Mar 27
• 1008 citations
  Peroxisome proliferator–activated receptor γ coactivator-1 promotes cardiac mitochondrial biogenesis
  John J. Lehman, Philip M. Barger, Attila Kovacs, Jeffrey E. Saffitz, Denis M. Medeiros, Daniel P. Kelly> ;The Journal of Clinical Investigation. 2000 Oct 1
• 96 citations
  Arachidonic acid release from aortic smooth muscle cells induced by [Arg8]vasopressin is largely mediated by calcium-independent phospholipase A2.
  John J. Lehman, Kathryn A. Brown, Sasanka Ramanadham, John Turk, Richard W. Gross> ;The Journal of Biological Chemistry. 1993 Oct 5
• 10 citations
  The Revised Developmental Test of Visual-Motor Integration Its Relation to the VMI, WISC-R, and Bender Gestalt For a Group of Elementary Aged Learning Disabled Students
  Michael J. Breen, Mary Carlson, Joanne Lehman> ;Journal of Learning Disabilities. 1985 Mar 1
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