JohnFrankLoveMDPhD, FIDSA(He/Him)

Infectious Disease • Gwynedd, PA

Global Regulatory Liaison

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Office
351 Sumneytown Pike
Gwynedd, PA 19454
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Education & Training

Beth Israel Deaconess Medical CenterFellowship, Infectious Disease, 2007 - 2012
University of ChicagoResidency, Internal Medicine, 2005 - 2007
Boston University School of MedicineClass of 2005

Certifications & Licensure

PA State Medical License 2015 - 2024
MA State Medical License 2008 - 2019
IL State Medical License 2005 - 2008
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Infectious Disease

Awards, Honors, & Recognition

FIDSA IDSA, 2023

Publications & Presentations

PubMed

23 citations
Inhibition of inflammasome-dependent interleukin 1β production by streptococcal NAD+-glycohydrolase: Evidence for extracellular activity
Dora Hancz, Elsa Westerlund, Benedicte Bastiat-Sempe, Onkar Sharma, Christine Valfridsson, Lena Meyer, John F. Love, Maghnus O'Seaghdha, Michael R. Wessels, Jenny L. P...> ;Mbio. 2017 Jul 18
62 citations
Streptolysin O and NAD-Glycohydrolase Prevent Phagolysosome Acidification and Promote Group A Streptococcus Survival in Macrophages
Benedicte Bastiat-Sempe, John F. Love, Natalie Lomayesva, Michael R. Wessels> ;Mbio. 2014 Oct 31
24 citations
Vitamin D and the Human Antimicrobial Peptide LL-37 Enhance Group A Streptococcus Resistance to Killing by Human Cells
John F. Love, Hien J. Tran-Winkler, Michael R. Wessels> ;Mbio. 2012 Nov 1
51 citations
Signal Transduction through CsrRS Confers an Invasive Phenotype in Group A Streptococcus
Hien J. Tran-Winkler, John F. Love, Ioannis Gryllos, Michael R. Wessels> ;Plos Pathogens. 2011 Oct 27
17 citations
Mn(II) binding by the anthracis repressor from Bacillus anthracis.
K. Ilker Sen, Andrzej Sienkiewicz, John F. Love, Johanna C. vanderSpek, Piotr G. Fajer, Timothy M. Logan> ;Biochemistry. 2006 Mar 14
18 citations
Sequence of ligand binding and structure change in the diphtheria toxin repressor upon activation by divalent transition metals.
Vijayaraghavan Rangachari, Vedrana Marin, Ewa A. Bienkiewicz, Maria Semavina, Luis Guerrero, John F. Love, John R. Murphy, Timothy M. Logan> ;Biochemistry. 2005 Apr 19
Prolylpeptide binding by the prokaryotic SH3-like domain of the diphtheria toxin repressor: a regulatory switch.
Wylie, G. P.,Rangachari, V.,Bienkiewicz, E. A.,Marin, V.,Bhattacharya, N.,Love, J. F.,Murphy, J. R.,Logan, T. M.> ;Biochemistry. 2005 Jan 11
21 citations
Genetic and biophysical studies of diphtheria toxin repressor (DtxR) and the hyperactive mutant DtxR(E175K) support a multistep model of activation
John F. Love, Johanna C. vanderSpek, Vedrana Marin, Luis Guerrero, Timothy M. Logan, John R. Murphy> ;Proceedings of the National Academy of Sciences of the United States of America. 2004 Feb 24
19 citations
The src Homology 3-Like Domain of the Diphtheria Toxin Repressor (DtxR) Modulates Repressor Activation through Interaction with the Ancillary Metal Ion-Binding Site
John F. Love, Johanna C. vanderSpek, John R. Murphy> ;Journal of Bacteriology. 2003 Apr 1
6 citations
Design and development of a novel genetic probe for the analysis of repressor–operator interactions
John F. Love, John R. Murphy> ;Journal of Microbiological Methods. 2002 Sep 1
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Press Mentions

Butler Health System Sees Uptick in Covid-19 Cases with Delta WaveAugust 23rd, 2021
County Approves Grant for Butler Health System to Expand COVID Testing OperationsOctober 28th, 2020
Ohio State, Abbott Labs Speed up COVID-19 Testing, Addressing Doctors' FrustrationMarch 31st, 2020
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