
John Robert Mascola MD
HIV/AIDS Medicine, Microbiology
Physician
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Rockville Pike# 8901Bethesda, MD 20889
Phone+1 301-295-4611
Fax+1 301-480-2788
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Education & Training
Naval Medical Center (San Diego)Residency, Internal Medicine, 1987 - 1989
Naval Medical Center (San Diego)Internship, Internal Medicine, 1985 - 1986
Georgetown University School of MedicineClass of 1985
Certifications & Licensure
CA State Medical License 1987 - 2022
Awards, Honors, & Recognition
- Elected Member The American Society for Clinical Investigation, 2002
Publications & Presentations
PubMed
- Canonical Antibodies Adopt Distinct Binding Modes to Recognize Viral Glycan Shields.Jiaxuan Cheng, Evan M Cale, Amirabbas Maghsoudi, Matthew S Sutton, Nancy S Longo
Advanced Science. 2026-08-14 - Combination therapy with broadly neutralizing antibodies, antiretroviral therapy and CCR5 blockade limits viral reservoir seeding in infant macaque model of HIV.Jonah B Sacha, Tracy Ordonez, Shilpi Pandey, Gabriela Webb, Philip Barnette
Nature Microbiology. 2026-08-10 - 1 citationsHIV broadly neutralizing antibody escape dynamics drive the outcome of AAV-vectored immunotherapy in humanized mice.Nicolas M S Galvez, Adam D Nitido, Seo Bin Yoo, Yi Cao, Cailin E Deal
Immunity. 2026-03-10
Journal Articles
- Evaluation of the mRNA-1273 Vaccine Against SARS-CoV-2 in Nonhuman PrimatesJohn R Mascola, The New England Journal of Medicine
- Monoclonal Antibodies for Prevention and Treatment of COVID-19John R Mascola, Myron S Cohen, JAMA
- Structure-Based Design of a Quadrivalent Fusion Glycoprotein Vaccine for Human Parainfluenza Virus Types 1–4John Mascola, MD, Proceedings of the National Academy of Sciences
Authored Content
- Epitope-Based Vaccine Design Yields Fusion Peptide-Directed Antibodies That Neutralize Diverse Strains of HIV-1June 2020
Press Mentions
NIAID Vaccine R&D Director Who Collaborated with Moderna on COVID-19 Vaccine to RetireFebruary 16th, 2022
Vaccine Makers Pursue Omicron-Targeted Shots That Health Officials Say Might Not Be NeededJanuary 14th, 2022
Covid-19 Vaccine Makers Assess Omicron ResponseNovember 29th, 2021
Grant Support
- Isolation And Deep Sequencing Of Monoclonal Antiobodies Against HIVNational Institute Of Allergy And Infectious Diseases2011
- Determination Of The Neutralization Specificity In Broadly Neutralizing HIV SERANational Institute Of Allergy And Infectious Diseases2010–2011
- Preclinical Evaluation Of Neutralizing Antibodies Elicited By HIV-1 ImmunogensNational Institute Of Allergy And Infectious Diseases2009–2011
- Non-Human Primate Immunogenicity Studies Of HIV-1 ImmunogensNational Institute Of Allergy And Infectious Diseases2009–2011
- NON Human Primate Models Of SIV And HIV Immune ProtectionNational Institute Of Allergy And Infectious Diseases2009–2011
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