JohnAndrewMengsholMD,PhD, FACG

PubMed

• 1 citations
  Baseline Features and Reasons for Nonparticipation in the Colonoscopy Versus Fecal Immunochemical Test in Reducing Mortality From Colorectal Cancer (CONFIRM) Study, a ...
  Douglas J Robertson, Jason A Dominitz, Alexander Beed, Kathy D Boardman, Barbara J Del Curto, Peter D Guarino, Thomas F Imperiale, Andrew LaCasse, Meaghan F Larson, Sa...> ;JAMA Network Open. 2023 Jul 3
• 36 citations
  HCV‐infected cells and differentiation increase monocyte immunoregulatory galectin‐9 production
  Noah M. K. Harwood, Lucy Golden-Mason, Linling Cheng, Hugo R. Rosen, John A. Mengshol> ;Journal of Leukocyte Biology. 2016 Mar 1
• 12 citations
  Octreotide: A Drug Often Used in the Critical Care Setting but Not Well Understood
  Mallory M. Chan, Michael M. Chan, John A. Mengshol, Douglas N. Fish, Edward D. Chan> ;Chest. 2013 Dec 1
• 156 citations
  A Crucial Role for Kupffer Cell-Derived Galectin-9 in Regulation of T Cell Immunity in Hepatitis C Infection
  John A. Mengshol, Lucy Golden-Mason, Tomohiro Arikawa, Maxwell L. Smith, Toshiro Niki, Ryan Mcwilliams, Jessica A. Randall, Rachel H. McMahan, Michael A. Zimmerman, Ma...> ;Plos One. 2010 Mar 4
• 37 citations
  Impaired plasmacytoid dendritic cell maturation and differential chemotaxis in chronic hepatitis C virus: associations with antiviral treatment outcomes
  John A. Mengshol, Lucy Golden-Mason, Nicole Castelblanco, KyungAh Im, Stephanie M. Dillon, Cara C. Wilson, Hugo R. Rosen> ;Gut. 2009 Jul 1
• 85 citations
  Mechanisms of Disease: HCV-induced liver injury.
  John A. Mengshol, Lucy Golden-Mason, Hugo R. Rosen> ;Nature Clinical Practice. Gastroenterology & Hepatology. 2007 Nov 1
• 294 citations
  Upregulation of PD-1 Expression on Circulating and Intrahepatic Hepatitis C Virus-Specific CD8+ T Cells Associated with Reversible Immune Dysfunction
  Lucy Golden-Mason, Brent E. Palmer, Jared Klarquist, John A. Mengshol, Nicole Castelblanco, Hugo R. Rosen> ;Journal of Virology. 2007 Sep 1
• 131 citations
  Matrix metalloproteinases as therapeutic targets in arthritic diseases: Bull's‐eye or missing the mark?
  John A. Mengshol, Kimberlee S. Mix, Constance E. Brinckerhoff> ;Arthritis and Rheumatism. 2002 Jan 1
• 200 citations
  IL-1 induces collagenase-3 (MMP-13) promoter activity in stably transfected chondrocytic cells: requirement for Runx-2 and activation by p38 MAPK and JNK pathways.
  John A. Mengshol, Matthew P. Vincenti, Constance E. Brinckerhoff> ;Nucleic Acids Research. 2001 Nov 1
• 58 citations
  A synthetic triterpenoid selectively inhibits the induction of matrix metalloproteinases 1 and 13 by inflammatory cytokines
  Kimberlee S. Mix, John A. Mengshol, Ulrike Benbow, Matthew P. Vincenti, Michael B. Sporn, Constance E. Brinckerhoff> ;Arthritis and Rheumatism. 2001 May 1
• 528 citations
  Interleukin‐1 induction of collagenase 3 (matrix metalloproteinase 13) gene expression in chondrocytes requires p38, c‐jun N‐terminal kinase, and nuclear factor κB: Di...
  John A. Mengshol, Matthew P. Vincenti, Charles I. Coon, Aaron Barchowsky, Constance E. Brinckerhoff> ;Arthritis and Rheumatism. 2000 Apr 1
• 74 citations
  Cloning of the gene for interstitial collagenase-3 (matrix metalloproteinase-13) from rabbit synovial fibroblasts: differential expression with collagenase-1 (matrix m...
  Matthew P. Vincenti, Charles I. Coon, John A. Mengshol, S Yocum, P Mitchell, Constance E. Brinckerhoff> ;The Biochemical Journal. 1998 Apr 1
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Journal Articles

• Somatosatin and octreotide: drugs not uncommonly used but not commonly understood  
  Chan, M. M., Chan M. M., Mengshol, J.A., Fish D. N., Chan E. D, Chest, 1/1/2013
• A crucial role for Kupffer cell-derived galectin-9 in regulation of T cell immunity in chronic hepatitis C infection  
  Mengshol, J.A.*, Golden-Mason, L.*, Arikawa, T., Smith, M., Niki, T., McWilliams, R., Randall, J., McMahan, R., Rangachari, M., Dobrinskikh, E., Busson, P., Polyak, S...., PLoS ONE, 1/1/2010
• Impaired Plasmacytoid Dendritic Cell Maturation and Differential Chemotaxis in Chronic HCV: Associations with Antiviral Treatment Outcomes  
  Mengshol, J. A., Golden-Mason, L., Castelblanco, N., Im, K., Dillon, S., Wilson, C. C., Rosen, H. R. for the Virahep-C Study Group, Gut, 1/1/2009
• Mechanisms of Disease: HCV-induced liver injury  
  Mengshol, J. A., Golden-Mason, L., Rosen, H. R, Nat Clin Pract Gastroeneterol and Hepatol, 1/1/2007
• How Hepatitis C Injures the Liver  
  Mengshol, J. A., Golden-Mason, L., Rosen, H. R, AASLD Postgraduate Course, 1/1/2006
• Matrix Metalloproteinases as Therapeutic Targets in Arthritic Diseases: Bulls-Eye or Missing the Mark?  
  Mengshol, J. A., Mix, K.S., Brinckerhoff, C.E, Arthritis and Rheumatism, 1/1/2002
• A Synthetic Triterpenoid Selectively Inhibits the Induction of Matrix Metalloproteinases 1 and 13 by Inflammatory Cytokines  
  Mix, K. S., Mengshol, J. A., Benbow, U., Vincenti, M.P., Sporn, M.B., Brinckerhoff, C. E., Arthritis and Rheumatism, 1/1/2001
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  Mengshol, J. A., Vincenti, M.P., Coon, C.I., Barchowsky, A., Brinckerhoff, C. E., Arthritis and Rheumatism, 1/1/2000
• Cloning of the gene for interstitial collagenase-3 (matrix metalloproteinase-13) from rabbit synovial fibroblasts: differential expression with collagenase-1 (matrix m...  
  Vincenti, M.P., Coon, C. I., Mengshol, J. A., Yocum, S., Mitchell, P. Brinckerhoff, C. E., Biochem J, 1/1/1998
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Abstracts/Posters

• Macrophage Immunoregulatory Galectin-9 Production is increased by Contact with Hepatitis C Virus-infected Hepatocytes and Differentiation
  Harwood, N., Golden-Mason, L., Rosen, H. R., Mengshol, J.A., Hepatology, 10/1/2013
• Digestive Disease Week
  Mengshol, J.A, 1/1/2008
• Combination Antiviral Therapy Differentially Affects Dendritic Cell Chemokine Receptor and Maturation Marker Expression in Chronic Hepatitis C Infection
  Mengshol, J. A., Golden-Mason, L., Castelblanco, N., Im, K., Rosen, H.R., Gastroenterology, 1/1/2008
• Upregulation of Programmed Death-1 (PD-1) on HCV-specific and CMV-specific CD8+ T cells in Chronic HCV Infection Associated with Reversible Immune Exhaustion
  Golden-Mason, L., Palmer, B., Klarquist, J., Mengshol J.A., Castelblanco N., Rosen, H.R., Hepatology, 1/1/2007
• American College of Physicians, Colorado Chapter Annual Meeting
  Mengshol, J.A, 1/1/2005
• American Federation for Aging Research, American Aging Association grantee conference
  Mengshol, J.A, Madison, WI, 1/1/2001
• Gordon Research Conference on Matrix Metalloproteinases
  Mengshol, J.A, Ciocco, Italy, 1/1/2001
• Transcriptional Regulation of Collagenase-3 (MMP-13) by IL-1 in Chondrocytic Cells Requires Stable Chromatin Integration and the transcription factors RUNX-2 and AP-1
  Mengshol, J. A., Vincenti, M. P., Brinckerhoff, C. E., Arthritis and Rheumatism, 1/1/2001
• Effects of a Novel Triterpenoid, 2-Cyano-3,12-dioxoolean-1,9-dien-28-oic acid (CDDO), on Collagenase-3 (Matrix Metalloproteinase-13) Gene Expression
  K.S. Mix, J.A. Mengshol, M.P. Vincenti, T. Honda, G.W. Gribble, and M.B. Sporn, 91st American Association for Cancer Research Annual Meeting, San Francisco, CA, 4/1/2000
• American College of Rheumatology, Annual Meeting
  Mengshol, J.A, Philadelphia, PA, 1/1/2000
• Regulation of Collagenase-3 by Core Binding Factor Alpha-1 (Cbfa1) in Chondrocytic Cells
  Mengshol, J. A., Vincenti, M.P., Brinckerhoff, C.E., Arthritis and Rheumatism, 1/1/2000
• A Potential Chondroprotective Agent, 2-Cyano-3,12,-Dioxoolean-1,9-dien-28-Oic Acid (CDDO), Inhibits Collagenase (Matrix Metalloproteinase-1 and 13) Gene Expression and...
  Mix, K.S, Mengshol, J.A., Vincenti, M. P., Honda, T., Gribble, G.W., Sporn, M.B., Brinckerhoff, C. E, Arthritis and Rheumatism, 1/1/2000
• Interleukin-1 (IL-1) Induction of Collagenase-3 (MMP-13) Requires p38 MAPK Activity in Articular Chondrocytes
  Mengshol, J. A., Vincenti, M.P., Coon, C. I., Brinckerhoff, C. E., Arthritis and Rheumatism, 1/1/1999
• American College of Rheumatology, Annual Meeting
  Mengshol, J.A, San Francisco, CA, 1/1/1998
• Interleukin-1 (IL-1) Regulation of Collagenase-3 (MMP-13) Gene Expression
  Mengshol, J. A., Vincenti, M.P., Coon, C. I., Brinckerhoff, C. E., Arthritis and Rheumatism, 1/1/1998
• Lectins as microbicides and spermicides
  Hedrick, J.L., Mengshol J. A., and M.J. Wieduwilt, Molecular Biology of the Cell, 1/1/1994
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Lectures

• AASLD Liver meeting HCV pathogenesis parallel session 
  1/1/2013
• Clinical Cytometry Society Meeting 
  1/1/2009
• Hepatology Young Investigators Forum 
  Breckenridge, CO - 1/1/2009
• Denver Translational Immunology Symposium 
  1/1/2007
• American College of Rheumatology, International Annual Meeting 
  San Francisco, CA - 1/1/2001
• American College of Rheumatology, Annual Meeting 
  Boston, MA - 1/1/1999
• National M.D./Ph.D. Student Conference 
  Aspen, CO - 1/1/1998
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