JohnScudderMillarMD

PubMed

• 10 citations
  ILRUN, a Human Plasma Lipid GWAS Locus, Regulates Lipoprotein Metabolism in Mice
  Xin Bi, Takashi Kuwano, Paul C. Lee, John S. Millar, Li Li, Yachen Shen, Raymond E. Soccio, Nicholas J. Hand, Daniel J. Rader> ;Circulation Research. 2020 Nov 6
• 39 citations
  LDL-Cholesterol Reduction by ANGPTL3 Inhibition in Mice Is Dependent on Endothelial Lipase.
  Liya Wu, Mangala Meenakshi Soundarapandian, Adam Castoreno, John S. Millar, Daniel J. Rader> ;Circulation Research. 2020 Sep 25
• 32 citations
  Reduced Apolipoprotein M and Adverse Outcomes Across the Spectrum of Human Heart Failure.
  Julio A. Chirinos, Lei Zhao, Yi Jia, Cecilia Frej, Luigi Adamo, Douglas L. Mann, Swapnil V. Shewale, John S. Millar, Daniel J. Rader, Benjamin French, Jeff Brandimarto...> ;Circulation. 2020 May 5
• 4 citations
  Differential Effects of Roux-en-Y Gastric Bypass Surgery and Laparoscopic Sleeve Gastrectomy on Fatty Acid Levels.
  Sudipa Sarkar, Frederick Anokye-Danso, Jena Shaw Tronieri, John S. Millar, Naji Alamuddin, Thomas A. Wadden, Rexford S. Ahima> ;Obesity Surgery. 2019 Dec 1
• 19 citations
  Author Correction: Herbivorous turtle ants obtain essential nutrients from a conserved nitrogen-recycling gut microbiome.
  Yi Hu, Jon G. Sanders, Piotr Łukasik, Catherine L. D’Amelio, John S. Millar, David R. Vann, Yemin Lan, Justin A. Newton, Mark P. Schotanus, Daniel J. C. Kronauer, Naom...> ;Nature Communications. 2018 Jun 19
• 69 citations
  Herbivorous turtle ants obtain essential nutrients from a conserved nitrogen-recycling gut microbiome.
  Yi Hu, Jon G. Sanders, Piotr Łukasik, Catherine L. D’Amelio, John S. Millar, David R. Vann, Yemin Lan, Justin A. Newton, Mark P. Schotanus, Daniel J. C. Kronauer, Naom...> ;Nature Communications. 2018 Mar 6
• 7 citations
  Cholesterol metabolism in humans: a review of methods and comparison of results.
  John S. Millar, Marina Cuchel> ;Current Opinion in Lipidology. 2018 Feb 1
• 27 citations
  CRISPR/Cas9-Mediated Gene Editing in Human iPSC-Derived Macrophage Reveals Lysosomal Acid Lipase Function in Human Macrophages-Brief Report.
  Hanrui Zhang, Jianting Shi, Melanie A. Hachet, Chenyi Xue, Robert C. Bauer, Hongfeng Jiang, Wenjun Li, Junichiro Tohyama, John S. Millar, Jeffrey T. Billheimer, Michae...> ;Arteriosclerosis, Thrombosis, and Vascular Biology. 2017 Nov 1
• 58 citations
  CETP (Cholesteryl Ester Transfer Protein) Inhibition With Anacetrapib Decreases Production of Lipoprotein(a) in Mildly Hypercholesterolemic Subjects
  Tiffany Thomas, Haihong Zhou, Wahida Karmally, Rajasekhar Ramakrishnan, Stephen Holleran, Yang Liu, Patricia Jumes, John A. Wagner, Brian K. Hubbard, Stephen F. Previs...> ;Arteriosclerosis, Thrombosis, and Vascular Biology. 2017 Jul 20
• 79 citations
  A human APOC3 missense variant and monoclonal antibody accelerate apoC-III clearance and lower triglyceride-rich lipoprotein levels.
  Sumeet A. Khetarpal, Xuemei Zeng, John S. Millar, Cecilia Vitali, Amritha Varshini Hanasoge Somasundara, Paolo Zanoni, James A. Landro, Nicole Barucci, William J. Zava...> ;Nature Medicine. 2017 Aug 21
• 39 citations
  Hepatic protein phosphatase 1 regulatory subunit 3B (Ppp1r3b) promotes hepatic glycogen synthesis and thereby regulates fasting energy homeostasis
  Minal B. Mehta, Swapnil V. Shewale, Raymond N. Sequeira, John S. Millar, Nicholas J. Hand, Daniel J. Rader> ;The Journal of Biological Chemistry. 2017 Jun 23
• 30 citations
  Lack of MTTP Activity in Pluripotent Stem Cell-Derived Hepatocytes and Cardiomyocytes Abolishes apoB Secretion and Increases Cell Stress
  Ying Liu, Donna M. Conlon, Xin Bi, Katherine J. Slovik, Jianting Shi, Hailey I. Edelstein, John S. Millar, Ali Javaheri, Marina Cuchel, Evanthia E. Pashos, Jahangir Iq...> ;Cell Reports. 2017 May 16
• 12 citations
  Overexpression and deletion of phospholipid transfer protein reduce HDL mass and cholesterol efflux capacity but not macrophage reverse cholesterol transport.
  Takashi Kuwano, Xin Bi, Eleonora Cipollari, Tomoyuki Yasuda, William R. Lagor, Hannah J Szapary, Junichiro Tohyama, John S. Millar, Jeffrey T. Billheimer, Nicholas N. ...> ;Journal of Lipid Research. 2017 Jan 30
• 18 citations
  Effects of CETP inhibition with anacetrapib on metabolism of VLDL-TG and plasma apolipoproteins C-II, C-III, and E.
  John S. Millar, Michael E. Lassman, Tiffany Thomas, Rajasekhar Ramakrishnan, Patricia Jumes, Richard L. Dunbar, Emile M. deGoma, Amanda Baer, Wahida Karmally, Daniel S...> ;Journal of Lipid Research. 2017 Mar 17
• 22 citations
  A novel approach to measuring macrophage-specific reverse cholesterol transport in vivo in humans.
  Marina Cuchel, Anna Raper, Donna M. Conlon, Daniel A. Pryma, Richard Freifelder, Rahul Poria, Debra Cromley, Xiaoyu Li, Richard L. Dunbar, Benjamin French, Liming Qu, ...> ;Journal of Lipid Research. 2017 Apr 1
• 26 citations
  Reduced sterol regulatory element-binding protein (SREBP) processing through site-1 protease (S1P) inhibition alters oligodendrocyte differentiation in vitro.
  Hubert Monnerie, Micah Romer, Brigid K. Jensen, John S. Millar, Kelly L. Jordan-Sciutto, Sangwon F. Kim, Judith B. Grinspan> ;Journal of Neurochemistry. 2017 Jan 1
• 4 citations
  Cell lipid metabolism modulators 2-bromopalmitate, D609, monensin, U18666A and probucol shift discoidal HDL formation to the smaller-sized particles: implications for ...
  Duyen Quach, Cecilia Vitali, Fiona M. La, Angel X. Xiao, John S. Millar, Chongren Tang, Daniel J. Rader, Michael C. Phillips, Nicholas N. Lyssenko> ;Biochimica Et Biophysica Acta. 2016 Dec 1
• 95 citations
  Loss of Function of GALNT2 Lowers High-Density Lipoproteins in Humans, Nonhuman Primates, and Rodents
  Sumeet A. Khetarpal, Katrine T. Schjoldager, Christina Christoffersen, Avanthi Raghavan, Andrew C. Edmondson, Heiko Reutter, Bouhouche Ahmed, Reda Ouazzani, Gina M. Pe...> ;Cell Metabolism. 2016 Aug 9
• 25 citations
  Targeting ApoC-III to Reduce Coronary Disease Risk
  Sumeet A. Khetarpal, Arman Qamar, John S. Millar, Daniel J. Rader> ;Current Atherosclerosis Reports. 2016 Jul 21
• Lnc-ing Common Polymorphisms to Statin Responsiveness at the MYLIP Locus.
  Sumeet A. Khetarpal, John S. Millar> ;Circulation. Cardiovascular Genetics. 2016 Jun 1
• 6 citations
  Anacetrapib lowers LDL by increasing ApoB clearance in mildly hypercholesterolemic subjects.
  John S Millar, Gissette Reyes-Soffer, Patricia Jumes, Richard L Dunbar, Emil M deGoma, Amanda L Baer, Wahida Karmally, Daniel S Donovan, Hashmi Rafeek, Laura Pollan, J...> ;The Journal of Clinical Investigation. 2016 Apr 1
• 381 citations
  Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease
  Paolo Zanoni, Sumeet A. Khetarpal, Daniel B. Larach, Hancock-Cerutti Wf, John S. Millar, Marina Cuchel, Stephanie DerOhannessian, Anatol Kontush, Praveen Surendran, Da...> ;Science. 2016 Mar 11
• 29 citations
  Cholesteryl Ester Transfer Protein Inhibition With Anacetrapib Decreases Fractional Clearance Rates of High-Density Lipoprotein Apolipoprotein A-I and Plasma Cholester...
  Gissette Reyes-Soffer, John S. Millar, Colleen Ngai, Patricia Jumes, Ellie Coromilas, Bela F. Asztalos, Amy O. Johnson-Levonas, John A. Wagner, Daniel S. Donovan, Wahi...> ;Arteriosclerosis, Thrombosis, and Vascular Biology. 2016 Jan 1
• 26 citations
  Potent peroxisome proliferator-activated receptor-α agonist treatment increases cholesterol efflux capacity in humans with the metabolic syndrome.
  Amit Khera, John S. Millar, Giacomo Ruotolo, Ming Dauh Wang, Daniel J. Rader> ;European Heart Journal. 2015 Nov 14
• 13 citations
  ApoA-I-Directed Therapies for the Management of Atherosclerosis.
  John S. Millar, Marina Cuchel> ;Current Atherosclerosis Reports. 2015 Sep 3
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