JohnCO'ConnorMD

PubMed

• Key Lessons from Performance of the U.S. EPA Endocrine Disruptor Screening Program (EDSP) Tier 1 Male and Female Pubertal Assays.
  Stump, D. G.,O'Connor, J. C.,Lewis, J. M.,Marty, M. S.> ;Birth Defects Res. B Dev. Reprod. Toxicol.. 2014 Feb 11
• Evaluation of the reproductive and developmental toxicity of 6:2 fluorotelomer alcohol in rats.
  O'Connor, J. C.,Munley, S. M.,Serex, T. L.,Buck, R. C.> ;Toxicology. 2014 Jan 23
• Interlaboratory study comparison of the 15-day intact adult male rat screening assay: evaluation of an antithyroid chemical and a negative control chemical.
  Becker RA, Bergfelt DR, Borghoff S, Davis JP, Hamby BT, O'Connor JC, Kaplan AM, Sloan CS, Tyl RW, Wade M, Marty MS> ;Birth Defects Res. B Dev. Reprod. Toxicol.. 2012-02-01
• 90-day oral gavage toxicity study of 8-2 fluorotelomer alcohol in rats.
  Ladics GS, Kennedy GL, O'Connor J, Everds N, Malley LA, Frame SR, Gannon S, Jung R, Roth T, Iwai H, Shin-Ya S> ;Drug Chem Toxicol. 2008-01-01
• Lipopolysaccharide-induced depressive-like behavior is mediated by indoleamine 2,3-dioxygenase activation in mice.
  O'Connor, J. C., Lawson, M. A., André, C., Moreau, M., Lestage, J., Castanon, N., Kelley, K. W., Dantzer, R.> ;Mol Psychiatry. 2009 May
• Comparison of the effects of Wyeth-14,643 in Crl:CD BR and Fisher-344 rats.
  Biegel, L. B., Hurtt, M. E., Frame, S. R., Applegate, M., O'Connor, J. C., Cook, J. C.> ;Fundam Appl Toxicol. 1992 Nov
• MUC1 expression in human prostate cancer cell lines and primary tumors.
  O'Connor, J. C., Julian, J., Lim, S. D., Carson, D. D.> ;Prostate Cancer Prostatic Dis. 2005
• Subchronic toxicity study in rats with 1-methyl-3-propylimidazole-2-thione (PTI): effects on the thyroid.
  Biegel, L. B., Cook, J. C., O'Connor, J. C., Aschiero, M., Arduengo, A. J., Slone, T. W.> ;Fundam Appl Toxicol. 1995 Sep
• Weak estrogenic activity from continuous-release pellets.
  O'Connor, J. C., Cook, J. C., Van Pelt, C. S., Arnold, S. F., Obourn, J. D.> ;Reprod Toxicol. 1997 Jan 01
• Chronic toxicity and oncogenicity bioassay in rats with the chloro-s-triazine herbicide cyanazine.
  Bogdanffy, M. S., O'Connor, J. C., Hansen, J. F., Gaddamidi, V., Van Pelt, C. S., Green, J. W., Cook, J. C.> ;J Toxicol Environ Health Part A. 2000 Aug 25
• Effects of 17 beta-estradiol on serum hormone concentrations and estrous cycle in female Crl:CD BR rats: effects on parental and first generation rats.
  Biegel, L. B., Cook, J. C., Hurtt, M. E., O'Connor, J. C.> ;Toxicol Sci. 1998 Aug
• Mechanisms of extrahepatic tumor induction by peroxisome proliferators in male CD rats.
  Biegel, L. B., Hurtt, M. E., Frame, S. R., O'Connor, J. C., Cook, J. C.> ;Toxicol Sci. 2001 Mar
• Detection of dopaminergic modulators in a tier I screening battery for identifying endocrine-active compounds (EACs).
  O'Connor, J. C., Davis, L. G., Frame, S. R., Cook, J. C.> ;Reprod Toxicol. 2000 May 01
• Role of prolactin in chloro-S-triazine rat mammary tumorigenesis.
  O'Connor, J. C., Plowchalk, D. R., Van Pelt, C. S., Davis, L. G., Cook, J. C.> ;Drug Chem Toxicol. 2000 Nov
• An in vivo battery for identifying endocrine modulators that are estrogenic or dopamine regulators.
  O'Connor, J. C., Cook, J. C., Craven, S. C., Van Pelt, C. S., Obourn, J. D.> ;Fundam Appl Toxicol. 1996 Oct
• Effects of dietary 17 beta-estradiol exposure on serum hormone concentrations and testicular parameters in male Crl:CD BR rats.
  Cook, J. C., Johnson, L., O'Connor, J. C., Biegel, L. B., Krams, C. H., Frame, S. R., Hurtt, M. E.> ;Toxicol Sci. 1998 Aug
• 90-day feeding and one-generation reproduction study in Crl:CD BR rats with 17 beta-estradiol.
  Biegel, L. B., Flaws, J. A., Hirshfield, A. N., O'Connor, J. C., Elliott, G. S., Ladics, G. S., Silbergeld, E. K., Van Pelt, C. S., Hurtt, M. E., Cook, J. C., Frame, S...> ;Toxicol Sci. 1998 Aug
• Development of a Tier I screening battery for detecting endocrine-active compounds (EACs).
  Cook, J. C., Kaplan, M. A., Davis, L. G., O'Connor, J. C.> ;Regul Toxicol Pharmacol. 1997 Aug
• Evaluation of a Tier I screening battery for detecting endocrine-active compounds (EACs) using the positive controls testosterone, coumestrol, progesterone, and RU486.
  O'Connor, J. C., Davis, L. G., Frame, S. R., Cook, J. C.> ;Toxicol Sci. 2000 Apr
• Detection of thyroid toxicants in a tier I screening battery and alterations in thyroid endpoints over 28 days of exposure.
  O'Connor, J. C., Frame, S. R., Davis, L. G., Cook, J. C.> ;Toxicol Sci. 1999 Sep
• Detection of the environmental antiandrogen p,p-DDE in CD and long-evans rats using a tier I screening battery and a Hershberger assay.
  O'Connor, J. C., Frame, S. R., Davis, L. G., Cook, J. C.> ;Toxicol Sci. 1999 Sep
• Evaluation of the primary humoral immune response following exposure of male rats to 17beta-estradiol or flutamide for 15 days.
  Ladics, G. S., Smith, C., Nicastro, S. C., Loveless, S. E., Cook, J. C., O'Connor, J. C.> ;Toxicol Sci. 1998 Nov
• Ex vivo and in vitro testis and ovary explants: utility for identifying steroid biosynthesis inhibitors and comparison to a Tier I screening battery.
  Powlin, S. S., Cook, J. C., Novak, S., O'Connor, J. C.> ;Toxicol Sci. 1998 Nov
• An ongoing validation of a Tier I screening battery for detecting endocrine-active compounds (EACs).
  O'Connor, J. C., Cook, J. C., Slone, T. W., Makovec, G. T., Frame, S. R., Davis, L. G.> ;Toxicol Sci. 1998 Nov
• Sensitivity of a Tier I screening battery compared to an in utero exposure for detecting the estrogen receptor agonist 17 beta-estradiol.
  O'Connor, J. C., Frame, S. R., Biegel, L. B., Cook, J. C., Davis, L. G.> ;Toxicol Sci. 1998 Aug
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