JohnFPowellMD

PubMed

• Targeting the HTLV-I-Regulated BATF3/IRF4 Transcriptional Network in Adult T Cell Leukemia/Lymphoma.
  Nakagawa, M.,Shaffer, A. L.,Ceribelli, M.,Zhang, M.,Wright, G.,Huang, D. W.,Xiao, W.,Powell, J.,Petrus, M. N.,Yang, Y.,Phelan, J. D.,Kohlhammer, H.,Dubois, S. P.,Yoo, ...> ;Cancer Cell. 2018 Jul 31
• Association between Plasma Ceramides and Phosphatidylcholines and Hippocampal Brain Volume in Late Onset Alzheimer's Disease.
  Kim M, Nevado-Holgado A, Whiley L, Snowden SG, Soininen H, Kloszewska I, Mecocci P, Tsolaki M, Vellas B, Thambisetty M, Dobson RJB, Powell JF, Lupton MK, Simmons A, Ve...> ;J. Alzheimers Dis.. 2016-11-26
• ABCA7 p.G215S as potential protective factor for Alzheimer's disease.
  Sassi C, Nalls MA, Ridge PG, Gibbs JR, Ding J, Lupton MK, Troakes C, Lunnon K, Al-Sarraj S, Brown KS, Medway C, Clement N, Lord J, Turton J, Bras J, Almeida MR, Holste...> ;Neurobiol. Aging. 2016-10-01
• An Examination of Polygenic Score Risk Prediction in Individuals With First-Episode Psychosis.
  Vassos E, Di Forti M, Coleman J, Iyegbe C, Prata D, Euesden J, O'Reilly P, Curtis C, Kolliakou A, Patel H, Newhouse S, Traylor M, Ajnakina O, Mondelli V, Marques TR, G...> ;Biol. Psychiatry. 2016-08-06
• 79 citations
  The effect of increased genetic risk for Alzheimer's disease on hippocampal and amygdala volume
  Michelle K. Lupton, Lachlan T. Strike, Narelle K. Hansell, Wei Wen, Karen A. Mather, Nicola J. Armstrong, Anbupalam Thalamuthu, Katie L. McMahon, Greig I. de Zubicaray...> ;Neurobiology of Aging. 2016 Apr 1
• Influence of Coding Variability in APP-Aβ Metabolism Genes in Sporadic Alzheimer's Disease.
  Sassi C, Ridge PG, Nalls MA, Gibbs R, Ding J, Lupton MK, Troakes C, Lunnon K, Al-Sarraj S, Brown KS, Medway C, Lord J, Turton J, Morgan K, Powell JF, Kauwe JS, Cruchag...> ;PLoS ONE. 2016-01-01
• 189 citations
  A novel Alzheimer disease locus located near the gene encoding tau protein
  Gyungah Jun, Carla A. Ibrahim-Verbaas, Maria Vronskaya, J-C Lambert, Jaeyoon Chung, Adam C. Naj, Brian W. Kunkle, L-S Wang, J. C. Bis, Céline Bellenguez, Denise Harold...> ;Molecular Psychiatry. 2016 Jan 1
• Common polygenic variation enhances risk prediction for Alzheimer's disease.
  Escott-Price, V.,Sims, R.,Bannister, C.,Harold, D.,Vronskaya, M.,Majounie, E.,Badarinarayan, N.,Morgan, K.,Passmore, P.,Holmes, C.,Powell, J.,Brayne, C.,Gill, M.,Mead,...> ;Brain. 2015 Oct 23
• Stratified gene expression analysis identifies major amyotrophic lateral sclerosis genes.
  Jones AR, Troakes C, King A, Sahni V, De Jong S, Bossers K, Papouli E, Mirza M, Al-Sarraj S, Shaw CE, Shaw PJ, Kirby J, Veldink JH, Macklis JD, Powell JF, Al-Chalabi A> ;Neurobiol. Aging. 2015-05-01
• Alleles that increase risk for type 2 diabetes mellitus are not associated with increased risk for Alzheimer's disease.
  Proitsi P, Lupton MK, Velayudhan L, Hunter G, Newhouse S, Lin K, Fogh I, Tsolaki M, Daniilidou M, Pritchard M, Craig D, Todd S, Johnston JA, McGuinness B, Kloszewska I...> ;Neurobiol. Aging. 2014-12-01
• Exome sequencing identifies 2 novel presenilin 1 mutations (p.L166V and p.S230R) in British early-onset Alzheimer's disease.
  Sassi C, Guerreiro R, Gibbs R, Ding J, Lupton MK, Troakes C, Lunnon K, Al-Sarraj S, Brown KS, Medway C, Lord J, Turton J, Mann D, Snowden J, Neary D, Harris J, Bras J,...> ;Neurobiol. Aging. 2014-10-01
• A genome-wide association analysis of a broad psychosis phenotype identifies three loci for further investigation.
  Bramon E, Pirinen M, Strange A, Lin K, Freeman C, Bellenguez C, Su Z, Band G, Pearson R, Vukcevic D, Langford C, Deloukas P, Hunt S, Gray E, Dronov S, Potter SC, Tasha...> ;Biol. Psychiatry. 2014-03-01
• Alzheimer's disease susceptibility variants in the MS4A6A gene are associated with altered levels of MS4A6A expression in blood.
  Proitsi P, Lee SH, Lunnon K, Keohane A, Powell J, Troakes C, Al-Sarraj S, Furney S, Soininen H, Kłoszewska I, Mecocci P, Tsolaki M, Vellas B, Lovestone S, Hodges A> ;Neurobiol. Aging. 2014-02-01
• Common variant at 16p11.2 conferring risk of psychosis.
  Steinberg S, de Jong S, Mattheisen M, Costas J, Demontis D, Jamain S, Pietiläinen OPH, Lin K, Papiol S, Huttenlocher J, Sigurdsson E, Vassos E, Giegling I, Breuer R, F...> ;Mol. Psychiatry. 2014-01-01
• Missense variant in TREML2 protects against Alzheimer's disease.
  Benitez, B. A.,Jin, S. C.,Guerreiro, R.,Graham, R.,Lord, J.,Harold, D.,Sims, R.,Lambert, J. C.,Gibbs, J. R.,Bras, J.,Sassi, C.,Harari, O.,Bertelsen, S.,Lupton, M. K.,P...> ;Neurobiol. Aging. 2014 Jan 21
• Rare coding variants in the phospholipase D3 gene confer risk for Alzheimer's disease.
  Cruchaga, C.,Karch, C. M.,Jin, S. C.,Benitez, B. A.,Cai, Y.,Guerreiro, R.,Harari, O.,Norton, J.,Budde, J.,Bertelsen, S.,Jeng, A. T.,Cooper, B.,Skorupa, T.,Carrell, D.,...> ;Nature. 2013 Dec 18
• 2894 citations
  Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease
  Jean-Charles Lambert, Carla A. Ibrahim-Verbaas, Denise Harold, Adam C. Naj, Rebecca Sims, Céline Bellenguez, Gyungah Jun, Anita L. DeStefano, Joshua C. Bis, Gary W. Be...> ;Nature Genetics. 2013 Dec 1
• Genome-wide association analysis identifies 13 new risk loci for schizophrenia.
  Ripke, S.,O'Dushlaine, C.,Chambert, K.,Moran, J. L.,Kähler, A. K.,Akterin, S.,Bergen, S. E.,Collins, A. L.,Crowley, J. J.,Fromer, M.,Kim, Y.,Lee, S. H.,Magnusson, P. K...> ;Nat. Genet.. 2013 Oct
• Residual association at C9orf72 suggests an alternative amyotrophic lateral sclerosis-causing hexanucleotide repeat.
  Jones AR, Woollacott I, Shatunov A, Cooper-Knock J, Buchman V, Sproviero W, Smith B, Scott KM, Balendra R, Abel O, McGuffin P, Ellis CM, Shaw PJ, Morrison KE, Farmer A...> ;Neurobiol. Aging. 2013-09-01
• Entorhinal cortex thickness predicts cognitive decline in Alzheimer's disease.
  Velayudhan L, Proitsi P, Westman E, Muehlboeck J, Mecocci P, Vellas B, Tsolaki M, Kłoszewska I, Soininen H, Spenger C, Hodges A, Powell J, Lovestone S, Simmons A> ;J. Alzheimers Dis.. 2013-01-01
• Confirmation that the AKT1 (rs2494732) genotype influences the risk of psychosis in cannabis users.
  Di Forti M, Iyegbe C, Sallis H, Kolliakou A, Falcone MA, Paparelli A, Sirianni M, La Cascia C, Stilo SA, Marques TR, Handley R, Mondelli V, Dazzan P, Pariante C, David...> ;Biol. Psychiatry. 2012-11-15
• C9ORF72 repeat expansion in a large Italian ALS cohort: evidence of a founder effect.
  Ratti A, Corrado L, Castellotti B, Del Bo R, Fogh I, Cereda C, Tiloca C, D'Ascenzo C, Bagarotti A, Pensato V, Ranieri M, Gagliardi S, Calini D, Mazzini L, Taroni F, Co...> ;Neurobiol. Aging. 2012-10-01
• Genetic variants influencing human aging from late-onset Alzheimer's disease (LOAD) genome-wide association studies (GWAS).
  Shi H, Belbin O, Medway C, Brown K, Kalsheker N, Carrasquillo M, Proitsi P, Powell J, Lovestone S, Goate A, Younkin S, Passmore P, Morgan K> ;Neurobiol. Aging. 2012-08-01
• Functional and genetic analysis of haplotypic sequence variation at the nicastrin genomic locus.
  Hamilton G, Killick R, Lambert J, Amouyel P, Carrasquillo MM, Pankratz VS, Graff-Radford NR, Dickson DW, Petersen RC, Younkin SG, Powell JF, Wade-Martins R> ;Neurobiol. Aging. 2012-08-01
• Alzheimer's disease and age-related macular degeneration have different genetic models for complement gene variation.
  Proitsi, P., Lupton, M.K., Dudbridge, F., Tsolaki, M., Hamilton, G., Daniilidou, M., Pritchard, M., Lord, K., Martin, B.M., Craig, D., Todd, S., McGuinness, B., Hollin...> ;Neurobiol Aging. 2012 Aug
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