John Daniel Sheppard Jr. MD MMSc

Anterior Segment Related, Cornea & External Disease, Glaucoma Related, Uveitis

President, Virginia Eye Consultants Professor of Ophthalmology, Microbiology & Molecular Biology

241 Corporate BlvdNorfolk, VA 23502
Phone+1 757-622-2200
Fax+1 757-622-4866

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Summary

My practice includes referral cataract, corneal transplantation, ocular infection, ocular immunology, uveitis, complex surgical cases, 2nd opinions, ocular surface disease, dry eye, trauma and glaucoma in adult and pediatric patients. In addition I provide consultations, advisory boards, clinical trial participation, clinical trial design and expert opinions for pharmaceutical and surgical industry partners, academic and government institutions and medico-legal colleagues.

Education & Training

UC San FranciscoCornea, Uveitis, Immunology, Infection, International Blindness, 1986 - 1989
UPMC Medical EducationResidency, Ophthalmology, 1983 - 1986
United States NavyMMSc, Medicine, Brown University, 1979 - 1983
University of Virginia Medical CenterInternship, Pediatrics, 1978 - 1979
The Warren Alpert Medical School of Brown UniversityClass of 1978, MD, Sigma Xi Honorary

The following disclaimer is related to board certifications obtained from ABMS®, denoted by the ABMS® logo.

This information is proprietary data maintained in a copyrighted database owned by the American Board of Medical Specialties®. The display and presence of ABMS Data in no way constitutes any affiliation, association with, or endorsement of any advertising, promotion, or sponsorship by ABMS and its affiliates and subsidiaries, the ABMS Member Boards, or ABMS board certified physicians and medical specialists. Copyright 2026 American Board of Medical Specialties®. All rights reserved.

The user is responsible for ensuring that the profile obtained in this directory is the profile of the physician or medical specialist being sought.

A self-designated specialty, subspecialty, or practice area neither implies nor is equivalent to ABMS board certification or the existence of specialized training by or competence of a physician or medical specialist.

Certifications & Licensure

VA State Medical License 1988 - 2026
FL State Medical License 2015 - 2019
PA State Medical License 1983 - 1990
American Board of Ophthalmology Ophthalmology

Awards, Honors, & Recognition

CMS Meaningful Use Stage 2 Certification NextGen Ambulatory EHR, NextGen Healthcare, 2014-2017
CMS Meaningful Use Stage 1 Certification NextGen Ambulatory EHR, NextGen Healthcare, 2014-2017
CMS Meaningful Use Stage 1 Certification NextGen Ambulatory EHR, NextGen Healthcare, 2013

Clinical Trials

Randomized Study of Photodynamic Therapy Using Dihematoporphyrin in Patients With Corneal Neovascularization
COMPLETED
NA
Safety & Efficacy of Corneal Collagen Cross-Linking in Eyes With Keratoconus or Corneal Ectasia After Refractive Surgery
TERMINATED
PHASE3
A Placebo Controlled Comparison of Topical Zirgan Versus Genteal Gel for the Treatment of Adenovirus Conjunctivitis
COMPLETED
PHASE4

Publications & Presentations

PubMed

Updated ocular pharmacology for noninfectious uveitis: a comprehensive expert review.
Matthew D Spangler, Nila Kirupaharan, John D Sheppard
Expert Opinion on Pharmacotherapy. 2026-08-19
Comparing Global Operating Room Waste Generated From Cataract, Corneal, and Conjunctival Surgeries.
Aashri I Aggarwal, Maria A Henriquez, Enrica Sarnicola, Clara C Chan, Tanya Trinh
Cornea. 2026-06-19
Phase 3 Randomized Clinical Trial Evaluating the Safety of Reproxalap in Patients With Dry Eye Disease.
Nathan M Radcliffe, John Sheppard, Blake Simmons, Desiree Owen, Ashley Nguyen
Ophthalmology and Therapy. 2026-05-01

Press Mentions

Preparing the Ocular Surface for SurgeryFebruary 11th, 2026
Clinical Challenges: Treatment Options for Dry Eye DiseaseMay 16th, 2023
Bausch + Lomb Presents Data from Second Pivotal Phase 3 Trial of Investigational Treatment NOV03 (Perfluorohexyloctane) at the Association for Research in Vision and Ophthalmology Annual MeetingMay 3rd, 2022

Committees

Associate & Mentor Examiner, American Board of Ophthalmology 1993 - Present
Association for Research in Vision & Ophthalmology, Media & Information Committee 1999 - 2003
American Academy of Ophthalmology, Basic Clinical Sciences Committee 1998 - 2001
American Academy of Ophthalmology, Media & Information Committee 1995 - 1999