John A Spertus MD

Professor, Internal Medicine, University of Missouri, Kansas City School of Medicine

4320 Wornall RdSuite 65Kansas City, MO 64111
Phone+1 816-932-6100
Fax+1 816-461-6586

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Education & Training

University of WashingtonFellowship, Cardiovascular Disease, 1992 - 1996
University of WashingtonResidency, Internal Medicine, 1989 - 1992
University of California San Francisco School of MedicineClass of 1989

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Certifications & Licensure

MO State Medical License 1996 - 2027
WA State Medical License 1989 - 1996
American Board of Internal Medicine Cardiovascular Disease

Awards, Honors, & Recognition

Elected Member The American Society for Clinical Investigation, 2006
Fellow (FACC) American College of Cardiology

Clinical Trials

Transforming PCI Informed Consent Into an Evidence-based Decision-making Tool
COMPLETED
Patient-centered Outcomes Related to TReatment Practices in Peripheral Arterial Disease: Investigating Trajectories (PORTRAIT)
COMPLETED
Angina Prevalence and Provider Evaluation of Angina Relief
COMPLETED

Publications & Presentations

PubMed

Lessons learned from the feasibility phase of the REvascularization CHoices Among Under-Represented Groups Evaluation (RECHARGE) trial program.
Mario Gaudino, Gregg W Stone, John Puskas, Katherine Krieger, Bjorn Redfors
American Heart Journal. 2026-11-01
Association Between Maximum Temperature 24 Hours After Resuscitation and Survival for In-Hospital Cardiac Arrest.
Omar Cantu-Martinez, Mohammad Abdel Jawad, Kevin F Kennedy, Andrew A Girard, Nobuhiro Ikemura
Journal of the American Heart Association. 2026-08-20
Sex differences in coronary disease health Status outcomes: the ISCHEMIA trial.
Anna Grodzinsky, Yoon J Cho, Philip G Jones, Leslee J Shaw, C Noel Bairey Merz
European Heart Journal. Quality of Care & Clinical Outcomes. 2026-08-11

Journal Articles

Potential Association of the ISCHEMIA Trial with the Appropriate Use Criteria Ratings for Percutaneous Coronary Intervention in Stable Ischemic Heart Disease
John A Spertus, Manesh R Patel, JAMA Internal Medicine
Association of Perceived Stress Levels with Long-Term Mortality in Patients with Peripheral Artery Disease
Poghni Peri-Okonny, John A Spertus, JAMA Network Open
Comparison of Patient-Reported vs Physician-Estimated Angina in Patients Undergoing Elective and Urgent Percutaneous Coronary Intervention
Andy T Tran, John A Spertus, JAMA Network Open

Lectures

Diagnostic Testing in Older Adult Patients with Coronary Artery Disease: Choosing Wisely
2019 ACC Scientific Session & Expo, New Orleans - 3/18/2019
What Every Cardiologist Should Know: QoL Improvements Following Revascularization for Stable Angina.
2019 ACC Scientific Session & Expo, New Orleans - 3/17/2019
Why We Need to Incorporate Patient Reported Outcomes in Heart Failure Guidelines
2019 ACC Scientific Session & Expo, New Orleans - 3/16/2019

Authored Content

Association of Perceived Stress Levels with Long-Term Mortality in Patients with Peripheral Artery DiseaseJune 2020
Comparison of Patient-Reported vs Physician-Estimated Angina in Patients Undergoing Elective and Urgent Percutaneous Coronary InterventionJune 2020
Omission of Heart Transplant Recipients from the Appropriate Use Criteria for Revascularization and the Ramifications on Heart Transplant CentersApril 2020

Press Mentions

UNR Med’s Doctor of Medicine Class of 2026 Enters the Profession of MedicineMay 15th, 2026
Heart Failure Patient Questionnaire Predicts Hospitalization and Mortality: StudyJune 25th, 2025
SGLT2 Inhibitors: From Glucose-Lowering to Cardio ProtectionJune 13th, 2025

Grant Support

The Heart Outcomes for Pregnancy Expectations StudyUNIVERSITY OF MISSOURI KANSAS CITY2024–2028
CARDIOVASCULAR OUTCOMES RESEARCH TRAINING PROGRAMUNIVERSITY OF MISSOURI KANSAS CITY2012–2027
Transforming PCI Informed Consent Into An Evidence-Based Decision-Making ToolNational Heart, Lung, And Blood Institute2009–2010
Investigating Racial Disparities In Outcomes After AMINational Heart, Lung, And Blood Institute2005–2009
Risk-Adjustment Of 1-Year Health Status Outcomes In CADAgency For Healthcare Research And Quality2000–2003