
John Michael Stafford MD PhD
Diabetes, Lipid Metabolism
Professor and Division Director, Endocrinology, Diabetes, and Metabolism, The Ohio State University College of Medicine
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6700 University Blvd Ste 4cDublin, OH 43016
Phone+1 614-685-3333
Fax+1 614-293-0077
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Summary
- John M. Stafford, MD, PhD, is a physician-scientist at The Ohio State University Wexner Medical Center whose research focuses on the mechanisms by which obesity and diabetes contribute to risk of metabolic associated fatty liver disease (MAFLD) and cardiovascular disease. A major focus of his research group is understanding male-female differences in risk of metabolic and cardiovascular disease. Dr. Stafford is the Division Director and Tenured Professor of Medicine in the Division of Endocrinology, Diabetes, and Metabolism. He is also director of the lipid clinic at the Columbus Ohio Veterans Administration Healthcare System. Dr. Stafford completed his MD, PhD training at Vanderbilt University Medical Center, where his graduate studies defined how metabolic signals are coordinated at the level of gene transcription. His medical residency and fellowship in Endocrinology were also performed at Vanderbilt. Dr. Stafford directs an active research program in obesity and lipid metabolism funded by the American Diabetes Association, American Heart Association, The National Institutes of Health, and the Department of Veterans Affairs.
Education & Training
Vanderbilt University Medical CenterFellowship, Endocrinology, Diabetes, and Metabolism, 2005 - 2008
Vanderbilt University Medical CenterResidency, Internal Medicine, 2003 - 2005
Vanderbilt University School of MedicineClass of 2003
Certifications & Licensure
OH State Medical License 2025 - 2027
TN State Medical License 2005 - 2026
American Board of Internal Medicine Endocrinology, Diabetes and Metabolism
Publications & Presentations
PubMed
- Repairing Atp10D in C57Bl/6J mice restores protein expression but does not mitigate metabolic stress from high fat diet.Alexander J Mansueto, Adriana C Norris, Eugenia M Yazlovitskaya, Lin Zhu, Joey Lu
Scientific Reports. 2026-07-07 - Estradiol treatment induces both shared and unique gene regulation and networks in adipose cell types of gonadectomized obese XX and XY mice.Yutian Zhao, Ruoshui Liu, Jonathan P Ng, Sophia Yu, In Sook Ahn
Biology of Sex Differences. 2026-02-23 - 1 citationsSex‑specific cardiovascular risk in estrogen‑treated androgen‑deprived males: metabolic characterization of glucose, adipose, and lipid pathways.Ariel S Thorson, Kelsey Pinckard Schaefers, Bridget Litts, Jeffrey Rein, Sharmila Adapa
Cardiovascular Diabetology. 2026-02-02
Journal Articles
- CETP Inhibition Improves HDL Function but Leads to Fatty Liver and Insulin Resistance in CETP-Expressing Transgenic Mice on a High-Fat DietLin Zhu, Thao Luu, Christopher H. Emfinger, Bryan A Parks, Jeanne Shi, Elijah Trefts, Fenghua Zeng, Zsuzsanna Kuklenyik, Raymond C. Harris, David H. Wasserman, Sergio ..., Diabetes, 9/2018
Grant Support
- CETP and Sex-Differences in Metabolic and Cardiovascular DiseaseNIH-NHLBI2019–2024
- Estrogen and coordinated metabolism of carbohydrate and lipids with obesityNIH/NIDDKPresent
Professional Memberships
- Member
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External Links
- Google Scholarhttps://scholar.google.com/citations?user=rhrZSjEAAAAJ&hl=en
- Lab Websitehttps://medsites.mc.vanderbilt.edu/staffordlab/stafford-lab
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