JohnMarshallStrongMD

PubMed

• Risk management for moisture related effects in dry manufacturing processes: a statistical approach.
  Quiroz, J.,Strong, J.,Zhang, L.> ;Pharm Dev Technol. 2014 Nov 12
• 19 citations
  Phase I study of the synthetic triterpenoid, 2-cyano-3, 12-dioxoolean-1, 9-dien-28-oic acid (CDDO), in advanced solid tumors.
  Giovanna Speranza, Martin Gutierrez, Shivaani Kummar, John M. Strong, Robert J. Parker, Jerry M. Collins, Yunkai Yu, Liang Cao, Anthony J. Murgo, James H. Doroshow, Al...> ;Cancer Chemotherapy and Pharmacology. 2012 Feb 1
• 124 citations
  Assessment of the Impact of Renal Impairment on Systemic Exposure of New Molecular Entities: Evaluation of Recent New Drug Applications
  Yifei Zhang, Lei Zhang, Abraham S, Apparaju S, T. C. Wu, John M. Strong, Xiao S, Atkinson Aj, Thummel Ke, Leeder Js, C S Lee, Gilbert J. Burckart, Lawrence J. Lesko, H...> ;Clinical Pharmacology and Therapeutics. 2009 Mar 1
• 69 citations
  Quantitative Evaluation of Pharmacokinetic Inhibition of CYP3A Substrates by Ketoconazole: A Simulation Study
  Ping Zhao, Isabelle Ragueneau-Majlessi, Lei Zhang, John M. Strong, Kellie S. Reynolds, René H. Levy, Kenneth E. Thummel, Shiew-Mei Huang> ;Journal of Clinical Pharmacology. 2009 Mar 1
• 123 citations
  A regulatory viewpoint on transporter-based drug interactions.
  Lei Zhang, Zhang Yd, John M. Strong, Kellie S. Reynolds, Shiew-Mei Huang> ;Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 2008 Sep 22
• 241 citations
  New Era in Drug Interaction Evaluation: US Food and Drug Administration Update on CYP Enzymes, Transporters, and the Guidance Process
  Shiew-Mei Huang, John M. Strong, Lei Zhang, Kellie S. Reynolds, Srikanth Nallani, Robert Temple, Sophia Abraham, Sayed Al Habet, Raman K. Baweja, Gilbert J. Burckart, ...> ;Journal of Clinical Pharmacology. 2008 Jun 1
• 72 citations
  Reaction of geldanamycin and C17-substituted analogues with glutathione: product identifications and pharmacological implications.
  Richard L. Cysyk, Robert J. Parker, Joseph J. Barchi, Patricia S. Steeg, Neil R. Hartman, John M. Strong> ;Chemical Research in Toxicology. 2006 Feb 7
• 107 citations
  Scientific perspectives on drug transporters and their role in drug interactions
  Lei Zhang, John M. Strong, Wei Qiu, Lawrence J. Lesko, Shiew-Mei Huang> ;Molecular Pharmaceutics. 2006 Jan 4
• 9 citations
  Rapid determination of N,N-diethyl-m-toluamide and permethrin in human plasma by gas chromatography- mass spectrometry and pyridostigmine bromide by high-performance l...
  Svetlana A. Cherstniakova, Gregory E. Garcia, John M. Strong, Daoqin Bi, Julie A. Weitz, Michael J. Roy, Louis R. Cantilena> ;Journal of Analytical Toxicology. 2006 Jan 1
• 18 citations
  Stability and comparative metabolism of selected felbamate metabolites and postulated fluorofelbamate metabolites by postmitochondrial suspensions.
  Robert J. Parker, Neil R. Hartman, Bryan A. Roecklein, Henry Mortko, Harvey J Kupferberg, James Stables, John M. Strong> ;Chemical Research in Toxicology. 2005 Nov 22
• 28 citations
  Reactivity of atropaldehyde, a felbamate metabolite in human liver tissue in vitro.
  Izet M. Kapetanovic, C.D. Torchin, John M. Strong, Wayne D. Yonekawa, Chuang Lu, Albert P. Li, Christine M. Dieckhaus, Webster L. Santos, Timothy L. Macdonald, R. Duan...> ;Chemico-Biological Interactions. 2002 Nov 10
• 12 citations
  Production of intracellular 35S-glutathione by rat and human hepatocytes for the quantification of xenobiotic reactive intermediates
  Neil R. Hartman, Richard L. Cysyk, Claudine Bruneau-Wack, Jean-Paul Thénot, Robert J. Parker, John M. Strong> ;Chemico-Biological Interactions. 2002 Nov 10
• 2 citations
  Bioavailablility of penclomedine and systemic exposure to 4-O-demethylpenclomedine in patients receiving oral and intravenous penclomedine
  Seamus O'Reilly, Neil R. Hartman, Katherine M. Bowling, Eric K. Rowinsky, Ross C. Donehower, Jerry M. Collins, John M. Strong> ;Cancer Chemotherapy and Pharmacology. 2001 Sep 1
• 19 citations
  Thioguanine Administered as a Continuous Intravenous Infusion to Pediatric Patients Is Metabolized to the Novel Metabolite 8-Hydroxy-Thioguanine
  Brenda J. Kitchen, Asher M. Moser, Elizabeth S. Lowe, Frank M. Balis, Brigitte C. Widemann, Lawrence W. Anderson, John M. Strong, Susan M. Blaney, S L Berg, Michelle O...> ;The Journal of Pharmacology and Experimental Therapeutics. 1999 Nov 1
• 35 citations
  Potentially Reactive Cyclic Carbamate Metabolite of the Antiepileptic Drug Felbamate Produced by Human Liver Tissue In Vitro
  Izet M. Kapetanovic, C.D. Torchin, Charles D. Thompson, Miller Thomas A, P J McNeilly, Timothy L. Macdonald, Harvey J. Kupferberg, J L Perhach, R D Sofia, John M. Strong> ;Drug Metabolism and Disposition. 1998 Nov 1
• 22 citations
  An Evaluation of the Hemizygous Transgenic Tg.AC Mouse for Carcinogenicity Testing of Pharmaceuticals. I. Evidence for a Confounding Nonresponder Phenotype
  James L. Weaver, Joseph F. Contrera, Barry A. Rosenzweig, Karol L. Thompson, Patrick J. Faustino, John M. Strong, Christopher D. Ellison, Lawrence W. Anderson, Hullaha...> ;Toxicologic Pathology. 1998 Jul 1
• 1 citations
  The In Vitro Metabolism of Penclomedine in Mouse, Rat, and Human Systems
  Neil R. Hartman, K. U. Leo, T. G. Brewer, John M. Strong> ;Drug Metabolism and Disposition. 1998 Jun 1
• 113 citations
  The involvement of cytochrome P450 3A4 in the N-demethylation of L-alpha-acetylmethadol (LAAM), norLAAM, and methadone.
  David E. Moody, Mario E. Alburges, Robert J. Parker, Jerry M. Collins, John M. Strong> ;Drug Metabolism and Disposition. 1997 Dec 1
• 52 citations
  Effect of albumin on the estimation, in vitro, of phenytoin Vmax and Km values: implications for clinical correlation.
  Linda K. Ludden, Thomas M. Ludden, Jerry M. Collins, Helen S. Pentikis, John M. Strong> ;The Journal of Pharmacology and Experimental Therapeutics. 1997 Jul 1
• 7 citations
  4-Demethylpenclomedine, an Antitumor-active, Potentially Nonneurotoxic Metabolite of Penclomedine'
  William R. Waud, Anita Tiwari, Steven M. Schmid, Tsu-Wen Shih, John M. Strong, Neil R. Hartman, Seamus O'Reilly, Robert F. Struck> ;Cancer Research. 1997 Mar 1
• 26 citations
  In vitro glucuronidation of D-23129, a new anticonvulsant, by human liver microsomes and liver slices.
  P J McNeilly, C. D. Torchin, L. W. Anderson, I. M. Kapetanovic, H. J. Kupferberg, John M. Strong> ;Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 1997 May 1
• 33 citations
  Identification of 2,6-xylidine as a major lidocaine metabolite in human liver slices.
  Robert J. Parker, Jerry M. Collins, John M. Strong> ;Drug Metabolism and Disposition. 1996 Nov 1
• 37 citations
  Cyclophosphamide and 4-Hydroxycyclophosphamide/aldophosphamide kinetics in patients receiving high-dose cyclophosphamide chemotherapy.
  Lawrence W. Anderson, T L Chen, O. M. Colvin, Louise B. Grochow, Jerry M. Collins, M J Kennedy, John M. Strong> ;Clinical Cancer Research. 1996 Sep 1
• 25 citations
  Stereoselective metabolism of a new anticonvulsant drug candidate, losigamone, by human liver microsomes
  C.D. Torchin, P J McNeilly, Izet M. Kapetanovic, John M. Strong, Harvey J. Kupferberg> ;Drug Metabolism and Disposition. 1996 Sep 1
• 9 citations
  Murine and human in vivo penclomedine metabolism.
  Neil R. Hartman, Seamus O'Reilly, Eric K. Rowinsky, Jerry M. Collins, John M. Strong> ;Clinical Cancer Research. 1996 Jun 1
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