JohnPieterTazelaarMD

PubMed

• 134 citations
  Prediction of MLH1 and MSH2 mutations in Lynch syndrome.
  J. Balmaña, David H. Stockwell, Ewout W. Steyerberg, Elena M. Stoffel, Amie M. Deffenbaugh, Julia Reid, Brian E. Ward, Thomas Scholl, Brant C. Hendrickson, John Tazela...> ;JAMA. 2006 Sep 27
• 1 citations
  Genetic testing in chronic pancreatitis.
  John P Tazelaar, Jeffrey A. Kant> ;Expert Review of Molecular Diagnostics. 2003 Nov 1
• 41 citations
  Regulated expression of erythropoietin from an AAV vector safely improves the anemia of β-thalassemia in a mouse model
  Julie Johnston, John Tazelaar, Victor M. Rivera, Tim Clackson, Guangping Gao, James M. Wilson> ;Molecular Therapy. 2003 Apr 1
• 106 citations
  Adenoviral transfer of HSP-70 into pulmonary epithelium ameliorates experimental acute respiratory distress syndrome
  Yoram G. Weiss, Alina Maloyan, John Tazelaar, Nichelle Raj, Clifford S. Deutschman> ;The Journal of Clinical Investigation. 2002 Sep 15
• 63 citations
  Preexisting Immunity to Adenovirus in Rhesus Monkeys Fails To Prevent Vector-Induced Toxicity
  Andrei N. Varnavski, Yi Zhang, Michael A. Schnell, John Tazelaar, Jean-Pierre Louboutin, Qian-Chun Yu, Adam Bagg, Guangping Gao, James M. Wilson> ;Journal of Virology. 2002 Jun 1
• 250 citations
  A pilot study of in vivo liver-directed gene transfer with an adenoviral vector in partial ornithine transcarbamylase deficiency.
  Steven E. Raper, Marc Yudkoff, Narendra Chirmule, Guangping Gao, Fred Nunes, Ziv J. Haskal, Emma E. Furth, Kathleen J. Propert, Michael B. Robinson, Susan Magosin, Hea...> ;Human Gene Therapy. 2002 Jan 1
• 24 citations
  Adenoviral vector transfection into the pulmonary epithelium after cecal ligation and puncture in rats.
  Yoram Weiss, John Tazelaar, Beth Gehan, Arthur Bouwman, Melpo Christofidou-Solomidou, Qian-Chun Yu, Nichelle Raj, Clifford S. Deutschman> ;Anesthesiology. 2001 Oct 1
• 17 citations
  Intra-arterial delivery of a recombinant adenovirus does not increase gene transfer to tumor cells in a rat model of metastatic colorectal carcinoma.
  David J. Maron, Hiroomi Tada, A. David Moscioni, John Tazelaar, Douglas L. Fraker, James M. Wilson, Francis R. Spitz> ;Molecular Therapy. 2001 Jul 1
• 42 citations
  Systemic IFN-β gene therapy results in long-term survival in mice with established colorectal liver metastases
  Hiroomi Tada, David J. Maron, Eugene Choi, James Barsoum, Hanqin Lei, Qing Xie, Wenbiao Liu, Lee Ellis, A. David Moscioni, John Tazelaar, Stephen Fawell, Xiao Qin, Kat...> ;The Journal of Clinical Investigation. 2001 Jul 1
• 267 citations
  Activation of innate immunity in nonhuman primates following intraportal administration of adenoviral vectors.
  Michael A. Schnell, Yi Zhang, John Tazelaar, Guangping Gao, Qian-Chun Yu, Ruth Qian, Shu-Jen Chen, Andrei N. Varnavski, Cynthia LeClair, Steven E. Raper, James M. Wilson> ;Molecular Therapy. 2001 May 1
• 305 citations
  Acute cytokine response to systemic adenoviral vectors in mice is mediated by dendritic cells and macrophages.
  Yi Zhang, Narendra Chirmule, Guangping Gao, Ruth Qian, Maria A. Croyle, Bindu Joshi, John Tazelaar, James M. Wilson> ;Molecular Therapy. 2001 May 1
• 20 citations
  Selective repopulation of normal mouse liver by hepatocytes transduced in vivo with recombinant adeno-associated virus.
  Shu-Jen Chen, John Tazelaar, James M. Wilson> ;Human Gene Therapy. 2001 Jan 1
• 45 citations
  Prolonged Correction of Hyperlipidemia in Mice with Familial Hypercholesterolemia Using an Adeno-Associated Viral Vector Expressing Very-Low-Density Lipoprotein Receptor
  Shu-Jen Chen, Daniel J. Rader, John Tazelaar, Masa-aki Kawashiri, Guangping Gao, James M. Wilson> ;Molecular Therapy. 2000 Sep 1
• 29 citations
  In vivo selection of hepatocytes transduced with adeno-associated viral vectors.
  Shu-Jen Chen, John Tazelaar, A. David Moscioni, James M. Wilson> ;Molecular Therapy. 2000 May 1
• 53 citations
  Partial correction of murine hemophilia A with neo-antigenic murine factor VIII.
  Rita Sarkar, Guangping Gao, Narendra Chirmule, John Tazelaar, Haig H. Kazazian> ;Human Gene Therapy. 2000 Apr 10
• 86 citations
  Route of administration determines induction of T-cell-independent humoral responses to adeno-associated virus vectors
  Weidong Xiao, Narendra Chirmule, Michael A. Schnell, John Tazelaar, Joseph V. Hughes, James M. Wilson> ;Molecular Therapy. 2000 Apr 1
• 42 citations
  Readministration of adenovirus vector in nonhuman primate lungs by blockade of CD40-CD40 ligand interactions.
  Narendra Chirmule, Steven E. Raper, Linda C. Burkly, David W. Thomas, John Tazelaar, Joseph V. Hughes, James M. Wilson> ;Journal of Virology. 2000 Apr 1
• 16 citations
  Th2-Dependent B Cell Responses in the Absence of CD40-CD40 Ligand Interactions
  Narendra Chirmule, John Tazelaar, James M. Wilson> ;Journal of Immunology. 2000 Jan 1
• 101 citations
  A phase I study of adenovirus-mediated transfer of the human cystic fibrosis transmembrane conductance regulator gene to a lung segment of individuals with cystic fibr...
  Jonathan B. Zuckerman, Cynthia B. Robinson, Karen McCoy, Richard Shell, Thomas J. Sferra, Narendra Chirmule, Susan Magosin, Kathleen J. Propert, Elsbeth C. Brown-Parr,...> ;Human Gene Therapy. 1999 Dec 10
• 6 citations
  Adenoviral vector-mediated gene therapy in the mouse lung : No role of Fas-Fas ligand interactions for elimination of transgene expression in bronchioepithelial cells
  Narendra Chirmule, Jennifer Moffett, Parag Dhagat, John Tazelaar, James M. Wilson> ;Human Gene Therapy. 1999 Nov 20
• 20 citations
  Wheat bran decreases aberrant crypt foci, preserves normal proliferation, and increases intraluminal butyrate levels in experimental colon cancer.
  Charlene Compher, Wendy L. Frankel, John Tazelaar, John A. Lawson, Shortie McKinney, Stanley Segall, Bruce Kinosian, Noel N. Williams, John L. Rombeau> ;JPEN. Journal of Parenteral and Enteral Nutrition. 1999 Sep 1
• 215 citations
  Stable transgene expression in rod photoreceptors after recombinant adeno-associated virus-mediated gene transfer to monkey retina
  Jean Bennett, Albert M. Maguire, Artur V. Cideciyan, Michael A. Schnell, Ernest Glover, Vibha Anand, Tomas S. Aleman, Narendra Chirmule, Abha R. Gupta, Yijun Huang, Gu...> ;Proceedings of the National Academy of Sciences of the United States of America. 1999 Aug 17
• 29 citations
  Repeated administration of adenoviral vectors in lungs of human CD4 transgenic mice treated with a nondepleting CD4 antibody.
  Narendra Chirmule, Alemseged Truneh, Sarah Ehlen Haecker, John Tazelaar, Guangping Gao, Steven E. Raper, Joseph V. Hughes, James M. Wilson> ;Journal of Immunology. 1999 Jul 1
• 138 citations
  Adeno-Associated Virus as a Vector for Liver-Directed Gene Therapy
  Weidong Xiao, Scott C. Berta, Min Min Lu, A. David Moscioni, John Tazelaar, James M. Wilson> ;Journal of Virology. 1998 Dec 1
• Direct intramuscular injection with recombinant AAV vectors results in sustained expression in a dog model of hemophilia.
  Monahan, P. E., Samulski, R. J., Tazelaar, J., Xiao, X., Nichols, T. C., Bellinger, D. A., Read, M. S., Walsh, C. E.> ;Gene Ther. 1998 Jan
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