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Office
8600 Old Georgetown Rd
Bethesda, MD 20814Phone+1 301-896-3517Fax+1 301-493-4259- Is this information wrong?
Education & Training
- National Institutes of Health Clinical CenterFellowship, Hematology and Medical Oncology, 1994 - 1996
- Vanderbilt University Medical CenterResidency, Internal Medicine, 1990 - 1994
- Medical University of South CarolinaClass of 1990
Certifications & Licensure
- MD State Medical License 2004 - 2025
Awards, Honors, & Recognition
- Elected Member The American Society for Clinical Investigation, 2010
Clinical Trials
- Collection and Storage of Umbilical Cord Stem Cells for Treatment of Sickle Cell Disease Start of enrollment: 2001 Nov 01
- Stem Cell Collection for Adult Volunteers Start of enrollment: 2002 Apr 29
- Evaluation of Hydroxyurea Plus L-arginine or Sildenafil to Treat Sickle Cell Anemia Start of enrollment: 2003 Mar 10
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Publications & Presentations
PubMed
- 4 citationsComparison of busulfan and total body irradiation conditioning on hematopoietic clonal dynamics following lentiviral gene transfer in rhesus macaques.Diana M Abraham, Richard J Lozano, Xavi Guitart, Jialiu A Liang, Ryland D Mortlock, Diego A Espinoza, Xing Fan, Allen Krouse, Aylin Bonifacino, So Gun Hong, Komudi Sin...> ;Molecular Therapy. Methods & Clinical Development. 2023 Mar 9
- 3 citationsReduction in vaso-occlusive events following stem cell transplantation in patients with sickle cell disease.Alexis Leonard, Dana Furstenau, Allistair Abraham, Deepika S Darbari, Robert S Nickel, Emily Limerick, Courtney Fitzhugh, Matt Hsieh, John F Tisdale> ;Blood Advances. 2023 Jan 24
- 10 citationsPhenotypic screening of the ReFRAME drug repurposing library to discover new drugs for treating sickle cell disease.Belhu Metaferia, Troy Cellmer, Emily B Dunkelberger, Quan Li, Eric R Henry, James Hofrichter, Dwayne Staton, Matthew M Hsieh, Anna K Conrey, John F Tisdale, Arnab K Ch...> ;Proceedings of the National Academy of Sciences of the United States of America. 2022 Oct 4
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Journal Articles
- Transfusion Support for Matched Sibling Allogeneic Hematopoietic Stem Cell Transplantation (1993–2010): Factors That Predict Intensity and Time to Transfusion Independ...Richard W Childs, John F Tisdale, Transfusion
Abstracts/Posters
- Preclinical Evaluation for Engraftment of Gene-Edited CD34+ Cells with a Sickle Cell Disease Mutation in a Rhesus Transplantation ModelJohn F. Tisdale, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
- Exploring the Drivers of Potential Clinical Benefit in Initial Patients Treated in the Hgb-206 Study of Lentiglobin for Sickle Cell Disease (SCD) Gene TherapyJohn F. Tisdale, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
- Resolution of Sickle Cell Disease Manifestations in Patients Treated with Lentiglobin Gene Therapy: Updated Results from the Phase 1/2 Hgb-206 Group C StudyJohn F. Tisdale, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
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Lectures
- Special Education Session on ASH Clinical Practice Guidelines on Sickle Cell Disease60th American Society of Hematology Annual Meeting - 12/2/2018
- Development of a Clinically Applicable Method for High-Efficiency Gene Correction of Plerixafor-Mobilized CD34+ Cells from Patients with Sickle Cell Disease2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
- Special Education Session on ASH Clinical Practice Guidelines on Sickle Cell Disease60th American Society of Hematology Annual Meeting - 12/1/2018
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Press Mentions
- Jasper Therapeutics Announces Positive Clinical Data from a Phase I/II Trial of Briquilimab as a Conditioning Treatment in Sickle Cell Disease and Beta ThalassemiaJanuary 3rd, 2023
- Health News | Experimental Gene Therapy Reverses Sickle Cell Disease for Years: StudyJanuary 1st, 2022
- Study Finds Experimental Gene Therapy Reverses Sickle Cell Disease for YearsDecember 27th, 2021
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Grant Support
- 14C As A Marker For Beta Cell Turnover In Adult HumansNational Center For Research Resources2011
- Nonmyeloablative Allogeneic PBSC In Globin DisordersNational Heart, Lung, And Blood Institute2009–2011
- Isolation, Characterization, And Transplantation Of Candidate Stem CellsNational Heart, Lung, And Blood Institute2009–2011
- A Preclinical Large Animal Model For Globin Gene TransferNational Heart, Lung, And Blood Institute2009–2011
- Development Of Improved Lentiviral Vectors For Human Gene Therapy ApplicationsNational Heart, Lung, And Blood Institute2009
- Development Of Improved Lentiviral Vectors For Human Gene Therapy ApplicationsNational Heart, Lung, And Blood Institute2008
- Isolation, Characterization, And Transplantation Of Candidate Stem CellsNational Institute Of Diabetes And Digestive And Kidney Diseases2007
- A Preclinical Large Animal Model For Globin Gene TransferNational Institute Of Diabetes And Digestive And Kidney Diseases2007
- Nonmyeloablative Allogeneic PBSC In Globin DisordersNational Institute Of Diabetes And Digestive And Kidney Diseases2005–2007
- Isolation, Characterization, And Transplantation Of CandNational Institute Of Diabetes And Digestive And Kidney Diseases2006
- A Preclinical Large Animal Model For Globin Gene TransfeNational Institute Of Diabetes And Digestive And Kidney Diseases2005–2006
- Isolation, Characterization, And Transplantation Of StemNational Institute Of Diabetes And Digestive And Kidney Diseases2005
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