JohnL.WagnerMD

Oncology • Charlottesville, VA

Hematologic Oncology

Hematopoietic Stem Cell Transplantation/ Univ of Virginia Healthcare

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Office
1240 Lee Street
Charlottesville, VA 22903
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Summary

Dr. John Wagner is an oncologist in Charlottesville VA and is affiliated with Thomas Jefferson University Hospitals. He received his medical degree from Temple University School of Medicine and has been in practice 28 years. He specializes in cellular therapy and hematopoietic stem cell transplantation and is experienced in amyloidosis, hematologic oncology, myelodysplasia, myelofibrosis, and CAR-T therapy.

Education & Training

University of WashingtonFellowship, Hematology and Medical Oncology, 1992 - 1995
University of MarylandResidency, Internal Medicine, 1989 - 1992
Lewis Katz School of Medicine at Temple UniversityClass of 1989

Certifications & Licensure

WV State Medical License 2023 - 2025
VA State Medical License 2022 - 2024
PA State Medical License 1999 - 2024
NJ State Medical License 2017 - 2023
DE State Medical License 2017 - 2023
MD State Medical License 1990 - 1993
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Hematology
American Board of Internal Medicine Medical Oncology

Awards, Honors, & Recognition

Regional Top Doctor Castle Connolly, 2020-2022
Patient-Centered Specialty Practice Recognition Program National Committee for Quality Assurance, 2014-2017
CMS Meaningful Use Stage 1 Certification Allscripts Enterprise EHR, Allscripts, 2011-2013

Clinical Trials

Study on the Safety and Effectiveness of VELCADE® in the Treatment of Graft-Versus-Host Disease Start of enrollment: 2005 Nov 01
Completed
Phase 2
Study of VELCADE® With Mitoxantrone and Etoposide for Leukemias Start of enrollment: 2006 Jan 01
Completed
Phase 1, Phase 2
Research Study to Determine if an Experimental Agent, LLME Can Decrease the Incidence and Severity of Graft-Versus-Host-Disease (GVHD) Following Blood (Hematopoietic) Stem Cell Transplantation Start of enrollment: 2004 Mar 01
Completed
Phase 1, Phase 2
Safety and Efficacy Study of Immunotherapy With Rituximab and Interleukin-2 in Patients With Non-Hodgkin's Lymphoma Start of enrollment: 2009 Feb 05
Completed
Phase 2
A Study of Bone Marrow Transplantation Using Fully-Matched Relatives as Donors for Patients With Hematological Malignancies Start of enrollment: 2008 Apr 10
Completed
Phase 2
Donor Stem Cell Transplant in Treating Patients With High-Risk Hematologic Malignancies Start of enrollment: 2010 May 01
Completed
Phase 2
A Research Study of Bone Marrow Transplantation From Unrelated or Partially Matched Related Donors Start of enrollment: 2011 Feb 10
Completed
Phase 2
Treatment of Sickle Cell Anemia With Stem Cell Transplant Start of enrollment: 2009 Sep 01
Terminated
Not Applicable
Combination of Pentostatin, Bendamustine and Ofatumumab for Treatment of Chronic Lymphocytic Leukemia and Lymphoma Start of enrollment: 2011 May 25
Terminated
Phase 1
A Two-Step Approach to Reduced Intensity Bone Marrow Transplant for Patients With Hematological Malignancies Start of enrollment: 2011 Aug 04
Completed
Phase 2
Phase I/II Study of Bendamustine in Combination With Ofatumumab, Carboplatin and Etoposide Start of enrollment: 2011 Nov 09
Completed
Phase 1, Phase 2
Donor Stem Cell Boost in Treating Patients With Low Blood Cells After Donor Stem Cell Transplant Start of enrollment: 2012 Aug 01
Withdrawn
Not Applicable
Reduced-Intensity Conditioning Before Donor Stem Cell Transplant in Treating Patients With High-Risk Hematologic Malignancies Start of enrollment: 2012 Dec 24
Completed
Phase 2
Sirolimus, Idarubicin, and Cytarabine in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia Start of enrollment: 2013 Mar 15
Completed
Early Phase 1
Sirolimus and Azacitidine in Treating Patients With High Risk Myelodysplastic Syndrome or Acute Myeloid Leukemia That is Recurrent or Not Eligible for Intensive Chemotherapy Start of enrollment: 2013 Jul 08
Active, not recruiting
Phase 2
Haploidentical Donor Hematopoietic Stem Cell Transplant in Treating Patients With Hematologic Malignancies Start of enrollment: 2013 May 17
Terminated
Phase 2
Allogeneic Hematopoietic Stem Cell Transplantation for High-Risk Hematologic Malignancies Using One Haploidentical Donor Start of enrollment: 2013 Nov 04
Completed
Phase 2
Bendamustine Hydrochloride, Bortezomib, and Dexamethasone in Treating Patients With Newly Diagnosed Multiple Myeloma Start of enrollment: 2014 Aug 25
Completed
Phase 2
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Publications & Presentations

PubMed

Allogeneic hematopoietic cell transplantation for blastic plasmacytoid dendritic cell neoplasm: a CIBMTR analysis.
Abid, M. B., Hemant S Murthy, Mei-Jie Zhang, Karen Chen, Sairah Ahmed, Uday Deotare, Siddhartha Ganguly, Ankit Kansagra, Fotios V Michelis, Taiga Nishihori, Mrinal Pat...> ;Blood Advances. 2023 Nov 28
Correction to: Impact of pre-transplant induction and consolidation cycles on AML allogeneic transplant outcomes: a CIBMTR analysis in 3113AML patients.
Michael Boyiadzis, Mei-Jie Zhang, Karen Chen, Hisham Abdel-Azim, Muhammad Bilal Abid, Mahmoud Aljurf, Ulrike Bacher, Talha Badar, Sherif M Badawy, Minoo Battiwalla, Ne...> ;Leukemia. 2023 May 1
3 citations
Impact of pre-transplant induction and consolidation cycles on AML allogeneic transplant outcomes: a CIBMTR analysis in 3113 AML patients.
Michael Boyiadzis, Mei-Jie Zhang, Karen Chen, Hisham Abdel-Azim, Muhammad Bilal Abid, Mahmoud Aljurf, Ulrike Bacher, Talha Badar, Sherif M Badawy, Minoo Battiwalla, Ne...> ;Leukemia. 2023 May 1
A Prospective, Randomized Trial Examining the Use of G-CSF Versus No G-CSF in Patients Post-Autologous Transplantation.
Dolores Grosso, Benjamin Leiby, Lindsay Wilde, Matthew Carabasi, Joanne Filicko-O'Hara, William O'Hara, John L Wagner, Gina Mateja, Onder Alpdogan, Adam Binder, Margar...> ;Transplantation and Cellular Therapy. 2022 Dec 1
2 citations
Outcomes of two-step haploidentical allogeneic stem cell transplantation in elderly patients with hematologic malignancies.
Xia Bi, Usama Gergis, John L Wagner, Matthew Carabasi, Joanne Filicko-O'Hara, William O'Hara, Thomas Klumpp, Pierluigi Porcu, Neal Flomenberg, Dolores Grosso> ;Bone Marrow Transplantation. 2022 Nov 1
3 citations
Outcomes of Allogeneic Hematopoietic Cell Transplantation in T Cell Prolymphocytic Leukemia: A Contemporary Analysis from the Center for International Blood and Marrow...
Hemant S Murthy, Kwang Woo Ahn, Noel Estrada-Merly, Hassan B Alkhateeb, Susan Bal, Mohamed A Kharfan-Dabaja, Bhagirathbhai Dholaria, Francine Foss, Lohith Gowda, Deepa...> ;Transplantation and Cellular Therapy. 2022 Apr 1
2 citations
The Two-Step Allogeneic Stem Cell Transplantation Approach Results in Rapid Engraftment and Excellent Outcomes in Patients with Lymphoid Malignancies.
Yang Yang, Usama Gergis, Matthew Carabasi, Joanne Filicko-O'Hara, John L Wagner, William O'Hara, Adam Binder, Onder Alpdogan, Ubaldo Martinez-Outschoorn, Pierluigi Por...> ;Transplantation and Cellular Therapy. 2022 Mar 1
9 citations
Allogeneic Transplantation to Treat Therapy-Related Myelodysplastic Syndrome and Acute Myelogenous Leukemia in Adults.
Leland Metheny, Natalie S. Callander, Aric C. Hall, Mei-Jei Zhang, Khalid Bo-Subait, Hai-Lin Wang, Vaibhav Agrawal, A. Samer Al-Homsi, Amer Assal, Ulrike Bacher, Amer ...> ;Transplantation and Cellular Therapy. 2021 Nov 1
10 citations
Bortezomib-Based Induction Is Associated with Superior Outcomes in Light Chain Amyloidosis Patients Treated with Autologous Hematopoietic Cell Transplantation Regardle...
, , , , , , , , , , , , , , , , , , , , , , , > ;Transplantation and Cellular Therapy. 2021 Mar 1
2 citations
An Examination of Cytomegalovirus, Socioeconomic Status, Race, and Ethnicity on Outcomes after Haploidentical Hematopoietic Transplantation.
Chetan Jeurkar, Benjamin E. Leiby, Joshua Banks, Amy Leader, Shannon Rudolph, Gina Mateja, Shaik Rashid, Matthew Carabasi, Joanne Filicko-O'Hara, William O'Hara, John ...> ;Transplantation and Cellular Therapy. 2021 Apr 1
1 citations
Phase I/II study of bendamustine in combination with ofatumumab, carboplatin, etoposide (BOCE) for relapsed or refractory aggressive B-cell non-Hodgkin lymphoma.
Jonathan Pan, Sushil Ghimire, S. Onder Alpdogan, Andrew E. Chapman, Matthew Carabasi, Martina DiMeglio, Jerald Z. Gong, Ubaldo E. Martinez-Outschoorn, Lewis J. Rose, M...> ;Leukemia & Lymphoma. 2021 Feb 23
2 citations
Low Nonrelapse Mortality after HLA-Matched Related 2-Step Hematopoietic Stem Cell Transplantation Using Cyclophosphamide for Graft-versus-Host Disease Prophylaxis and ...
Dolores Grosso, Matthew Carabasi, Joanne Filicko-O'Hara, John L. Wagner, William O'Hara, Michael Sun, Beth W. Colombe, Wenyin Shi, Maria Werner-Wasik, Shannon Rudolph,...> ;Biology of Blood and Marrow Transplantation. 2020 Oct 1
10 citations
The Presence of a CMV Immunodominant Allele in the Recipient Is Associated With Increased Survival in CMV Positive Patients Undergoing Haploidentical Hematopoietic Ste...
Dolores Grosso, Benjamin E. Leiby, Matthew Carabasi, Joanne Filicko-O'Hara, Sameh Gaballa, William O'Hara, John L. Wagner, Neal Flomenberg> ;Frontiers in Oncology. 2019 Sep 17
5 citations
Autologous Stem Cell Transplantation for Multiple Myeloma: Growth Factor Matters
Jason Chen, Jonathan Pan, Tingting Zhan, Sherilyn A. Tuazon, Neeraj Saini, William O'Hara, Joanne Filicko-O'Hara, Thomas R. Klumpp, Margaret Kasner, Matthew Carabasi, ...> ;Biology of Blood and Marrow Transplantation. 2019 Sep 1
79 citations
Outcomes of haploidentical vs matched sibling transplantation for acute myeloid leukemia in first complete remission
Armin Rashidi, Mehdi Hamadani, Mei-Jie Zhang, Hai-Lin Wang, Hisham Abdel-Azim, Mahmoud Aljurf, Amer Assal, Ashish Bajel, Asad Bashey, Minoo Battiwalla, Amer Beitinjane...> ;Blood Advances. 2019 Jun 25
10 citations
GRFS and CRFS in alternative donor hematopoietic cell transplantation for pediatric patients with acute leukemia
Rohtesh S. Mehta, Shernan G. Holtan, Tao Wang, Michael T. Hemmer, Stephen R. Spellman, Mukta Arora, Daniel R. Couriel, Amin M. Alousi, Joseph Pidala, Hisham Abdel-Azim...> ;Blood Advances. 2019 May 14
32 citations
Risk Factors for Graft-versus-Host Disease in Haploidentical Hematopoietic Cell Transplantation Using Post-Transplant Cyclophosphamide.
Annie Im, Armin Rashidi, Tao Wang, Michael T. Hemmer, Margaret L. MacMillan, Joseph Pidala, Madan Jagasia, Steven Z. Pavletic, Navneet S. Majhail, Daniel J. Weisdorf, ...> ;Biology of Blood and Marrow Transplantation. 2019 Mar 1
13 citations
Sirolimus enhances remission induction in patients with high risk acute myeloid leukemia and mTORC1 target inhibition
Margaret Kasner, Rosemarie Mick, Grace R. Jeschke, Matthew Carabasi, Joanne Filicko-O'Hara, Neal Flomenberg, Noelle V. Frey, Elizabeth O. Hexner, Selina M. Luger, Alis...> ;Investigational New Drugs. 2018 Apr 2
3 citations
Higher rates of relapse in maternal recipients of haploidentical hematopoietic stem cell transplantation from adult offspring donors for AML and myelodysplastic syndrome.
Praveen Ramakrishnan Geethakumari, Benjamin E. Leiby, Rasmi G. Nair, Seyfettin Onder Alpdogan, Matthew Carabasi, Joanne Filicko-O'Hara, Sameh Gaballa, Margaret Kasner,...> ;Bone Marrow Transplantation. 2017 Oct 1
12 citations
Acquired uniparental disomy in chromosome 6p as a feature of relapse after T-cell replete haploidentical hematopoietic stem cell transplantation using cyclophosphamide...
Dolores Grosso, Erica S. Johnson, Beth W. Colombe, Onder Alpdogan, Matthew Carabasi, Joanne Filicko-O'Hara, Sameh Gaballa, Margaret Kasner, Thomas R. Klumpp, Ubaldo E....> ;Bone Marrow Transplantation. 2017 Jan 9
Personalized fludarabine dosing to reduce nonrelapse mortality in hematopoietic stem-cell transplant recipients receiving reduced intensity conditioning.
Sanghavi K, Wiseman A, Kirstein MN, Cao Q, Brundage R, Jensen K, Rogosheske J, Kurtzweil A, Long-Boyle J, Wagner J, Warlick ED, Brunstein CG, Weisdorf DJ, Jacobson PA> ;Transl Res. 2016-09-01
19 citations
A Two-Step Haploidentical Versus a Two-Step Matched Related Allogeneic Myeloablative Peripheral Blood Stem Cell Transplantation
Sameh Gaballa, Neil Palmisiano, Onder Alpdogan, Matthew Carabasi, Joanne Filicko-O'Hara, Margaret Kasner, Walter K. Kraft, Benjamin E. Leiby, Ubaldo E. Martinez-Outsch...> ;Biology of Blood and Marrow Transplantation. 2016 Jan 1
Higher Dose of Mycophenolate Mofetil Reduces Acute Graft-versus-Host Disease in Reduced-Intensity Conditioning Double Umbilical Cord Blood Transplantation.
Bejanyan N, Rogosheske J, DeFor T, Lazaryan A, Esbaum K, Holtan S, Arora M, MacMillan ML, Weisdorf D, Jacobson P, Wagner J, Brunstein CG> ;Biol. Blood Marrow Transplant.. 2015-05-01
35 citations
A two-step approach to myeloablative haploidentical transplantation: low nonrelapse mortality and high survival confirmed in patients with earlier stage disease.
Dolores Grosso, Sameh Gaballa, Onder Alpdogan, Matthew Carabasi, Joanne Filicko-O'Hara, Margaret Kasner, Ubaldo E. Martinez-Outschoorn, John L. Wagner, William O'Hara,...> ;Biology of Blood and Marrow Transplantation. 2015 Apr 1
57 citations
Clostridium difficile colonization and disease in patients undergoing hematopoietic stem cell transplantation
Jackrapong Bruminhent, Zi-Xuan Wang, Carol Hu, John L. Wagner, Richard Sunday, Brent Bobik, Sarah E. Hegarty, Scott W. Keith, Seyfettin Onder Alpdogan, Matthew Carabas...> ;Biology of Blood and Marrow Transplantation. 2014 Sep 1
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Press Mentions

Koneksa Announces New Multi-Domain Model for Functional Status Assessment Enabled by Digital Health TechnologiesJanuary 31st, 2024

Grant Support

Molecular And Biochemical Analysis Of The Canine MHCNational Center For Research Resources1999–2001
Molecular And Biochemical Analysis Of The Canine MHCNational Center For Research Resources1997–1999