JohnWelchMD

PubMed

• Resonance Energy Transfer in a Genetically Engineered Polypeptide Results in Unanticipated Fluorescence Intensity.
  Welch, J. T.,Seeley, J. P.,Cotlet, M.,Eagleton, A. M.,Higashiya, S.> ;Chemistry. 2018 Nov 11
• Mutational landscape and response are conserved in peripheral blood of AML and MDS patients during decitabine therapy.
  Duncavage, E. J.,Uy, G. L.,Petti, A. A.,Miller, C. A.,Lee, Y. S.,Tandon, B.,Gao, F.,Fronick, C. C.,O'Laughlin, M.,Fulton, R. S.,Wilson, R. K.,Jacoby, M. A.,Cashen, A. ...> ;Blood. 2017 Jan 14
• The role of proline-containing peptide triads in β-sheet formation: A kinetic study.
  Takor, G. A.,Higashiya, S.,Sikirzhytski, V. K.,Seeley, J. P.,Lednev, I. K.,Welch, J. T.> ;Biopolymers. 2015 Feb 07
• Chimera-Induced Folding: Implications for Amyloidosis.
  Takor, G. A.,Higashiya, S.,Sorci, M.,Topilina, N. I.,Belfort, G.,Welch, J. T.> ;Biomacromolecules. 2014 Jul 09
• Sirtuin 6: a review of biological effects and potential therapeutic properties.
  Beauharnois, J. M.,Bolívar, B. E.,Welch, J. T.> ;Mol Biosyst. 2013 Jul
• Fibrillation mechanism of a model intrinsically disordered protein revealed by 2D correlation deep UV resonance Raman spectroscopy.
  Sikirzhytski V, Topilina NI, Takor GA, Higashiya S, Welch JT, Uversky VN, Lednev IK> ;Biomacromolecules. 2012-05-14
• Metallization of a genetically engineered polypeptide.
  Carlsen A, Higashiya S, Topilina NI, Dunn KA, Geer RE, Eisenbraun ET, Kaloyeros AE, Welch JT> ;Macromol Biosci. 2012-02-01
• Charge distribution and amyloid fibril formation: insights from genetically engineered model systems.
  Topilina NI, Sikirzhytsky V, Higashiya S, Ermolenkov VV, Lednev IK, Welch JT> ;Biomacromolecules. 2010-07-12
• A de novo designed 11 kDa polypeptide: model for amyloidogenic intrinsically disordered proteins.
  Topilina NI, Ermolenkov VV, Sikirzhytski V, Higashiya S, Lednev IK, Welch JT> ;Biopolymers. 2010-07-01
• Evolving treatment paradigms for acute cholecystitis: comment on "Surgical management of acute cholecystitis at a tertiary care center in the modern era".
  Welch, J. P.> ;Arch Surg. 2010 May 25
• Genetic engineering combined with deep UV resonance Raman spectroscopy for structural characterization of amyloid-like fibrils.
  Sikirzhytski V, Topilina NI, Higashiya S, Welch JT, Lednev IK> ;J. Am. Chem. Soc.. 2008-05-07
• Whither goest general surgery?
  Welch, J. P.> ;Arch Surg. 2008 May 21
• The synthesis and biological activity of pentafluorosulfanyl analogs of fluoxetine, fenfluramine, and norfenfluramine.
  Welch, J. T.,Lim, D. S.> ;Bioorg. Med. Chem.. 2007 Sep 04
• Beta-sheet folding of 11-kDa fibrillogenic polypeptide is completely aggregation driven.
  Topilina NI, Ermolenkov VV, Higashiya S, Welch JT, Lednev IK> ;Biopolymers. 2007-07-01
• Design and preparation of beta-sheet forming repetitive and block-copolymerized polypeptides.
  Higashiya S, Topilina NI, Ngo SC, Zagorevskii D, Welch JT> ;Biomacromolecules. 2007-05-01
• Reversible thermal denaturation of a 60-kDa genetically engineered beta-sheet polypeptide.
  Lednev IK, Ermolenkov VV, Higashiya S, Popova LA, Topilina NI, Welch JT> ;Biophys. J.. 2006-11-15
• Designer variable repeat length polypeptides as scaffolds for surface immobilization of quantum dots.
  Medintz IL, Sapsford KE, Clapp AR, Pons T, Higashiya S, Welch JT, Mattoussi H> ;J Phys Chem B. 2006-06-08
• Bilayer fibril formation by genetically engineered polypeptides: preparation and characterization.
  Topilina NI, Higashiya S, Rana N, Ermolenkov VV, Kossow C, Carlsen A, Ngo SC, Wells CC, Eisenbraun ET, Dunn KA, Lednev IK, Geer RE, Kaloyeros AE, Welch JT> ;Biomacromolecules. 2006-04-01
• Synthesis of mono- and difluoroacetyltrialkylsilanes and the corresponding enol silyl ethers.
  Higashiya S, Chung WJ, Lim DS, Ngo SC, Kelly WH, Toscano PJ, Welch JT> ;J. Org. Chem.. 2004-09-17
• Inhibition of dipeptidyl peptidase IV (DPP IV) by 2-(2-amino-1-fluoro-propylidene)-cyclopentanecarbonitrile, a fluoroolefin containing peptidomimetic.
  Zhao K, Lim DS, Funaki T, Welch JT> ;Bioorg. Med. Chem.. 2003-01-17
• Cancer of the rectum. Where are we? Where are we going?
  Welch JP, Welch CE> ;Arch Surg. 1993-06-01
• Inflammatory pseudotumors of the spleen.
  Safran D, Welch J, Rezuke W> ;Arch Surg. 1991-07-01
• Carcinoid tumors of the colon. A study of 72 patients.
  Rosenberg JM, Welch JP> ;Am. J. Surg.. 1985-06-01
• Cancer of the head of the pancreas: an institutional review with emphasis on surgical therapy.
  Rosenberg JM, Welch JP, Macaulay WP> ;J Surg Oncol. 1985-03-01
• Clostridium difficile colitis in surgical patients.
  Rosenberg JM, Walker M, Welch JP, Mullany L> ;Am. J. Surg.. 1984-04-01
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