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171 Ashley AveCharleston, SC 29425
Phone+1 843-792-1414
Fax+1 843-937-6110
Dr. Wrangle is on Doximity
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Education & Training
Johns Hopkins UniversityFellowship, Hematology and Medical Oncology, 2008 - 2011
Emory University School of MedicineResidency, Internal Medicine, 2005 - 2008
Tulane University School of MedicineClass of 2005
Certifications & Licensure
SC State Medical License 2014 - 2027
MD State Medical License 2008 - 2015
GA State Medical License 2005 - 2008
Awards, Honors, & Recognition
- CMS Meaningful Use Stage 2 Certification EpicCare Inpatient 2014 Certified EHR Suite, Epic Systems Corporation, 2017
- CMS Meaningful Use Stage 2 Certification EpicCare Ambulatory 2014 Certified EHR Suite, Epic Systems Corporation, 2017
- CMS Meaningful Use Stage 1 Certification Beacon Oncology 2014 Certified Module, Epic Systems Corporation, 2017
Clinical Trials
- Azacitidine and Entinostat in Treating Patients With Recurrent Advanced Non-Small Cell Lung Cancer
- Study of Rovalpituzumab Tesirine (SC16LD6.5) for Third-Line and Later Treatment of Subjects With Relapsed or Refractory Delta-Like Protein 3-Expressing Small Cell Lung Cancer Start of enrollment: 2016 Jan 25
Publications & Presentations
PubMed
- 5 citationsCounty-Level Cervical Cancer Screening Coverage and Differences in Incidence and Mortality.Trisha L Amboree, Jane R Montealegre, Haluk Damgacioglu, Brian Orr, John Wrangle
JAMA Network Open. 2025-08-01 - 12 citationsZipalertinib in Patients With Epidermal Growth Factor Receptor Exon 20 Insertion-Positive Non-Small Cell Lung Cancer Previously Treated With Platinum-Based Chemotherap...Zofia Piotrowska, Antonio Passaro, Danny Nguyen, Gerrina Ruiter, Ross A Soo
Journal of Clinical Oncology. 2025-07-20 - 24 citationsIL-15: from discovery to FDA approval.Zihai Li, John Wrangle, Kai He, Jonathan Sprent, Mark P Rubinstein
Journal of Hematology & Oncology. 2025-02-18
Press Mentions
DoD Grant Funds Hollings Researcher's Idea to Pursue Gene Therapy for CancerMarch 17th, 2025- Dr. Wrangle Discusses Phase 2b QUILT 3.055 Trial at IASLC 2024 World Conference on Lung CancerSeptember 23rd, 2024
- ImmunityBio Presents Positive Long-Term Overall Survival Data in Non-Small Cell Lung Cancer Patients and Announces Registrational Intent Phase 3 Trials with ANKTIVA® and Checkpoint Immunotherapy at World Conference on Lung CancerSeptember 9th, 2024
Grant Support
- Exploiting Lineage-Specific Dependencies in Solid Tumors: Using Transcription Factors to Drive Therapeutic Effect In SituMEDICAL UNIVERSITY OF SOUTH CAROLINA2024–2026
- Exploiting Lineage-Specific Dependencies in Solid Tumors: Using Transcription Factors to Drive Therapeutic Effect In SituMEDICAL UNIVERSITY OF SOUTH CAROLINA2024–2026
- Exploiting Lineage-Specific Dependencies in Solid Tumors: Using Transcription Factors to Drive Therapeutic Effect In SituMEDICAL UNIVERSITY OF SOUTH CAROLINA2024–2026
- Lymphocyte and inflammatory cytokine markers of response in the first-in-human combination of anti-PD-1 mAb and IL-15/IL-15Ra complexes and investigation of mediators of anti-tumor immune responsesMEDICAL UNIVERSITY OF SOUTH CAROLINA2019–2025
- Lymphocyte and inflammatory cytokine markers of response in the first-in-human combination of anti-PD-1 mAb and IL-15/IL-15Ra complexes and investigation of mediators of anti-tumor immune responsesMEDICAL UNIVERSITY OF SOUTH CAROLINA2019–2025
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