JonAKobashigawaMD

Cardiology • Los Angeles, CA

Adult Congenital Heart Disease, Cardiac Electrophysiology, Heart Failure & Transplantation

Clinical Professor of Medicine, UCLA

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Office
127 S. San Vicente Blvd
Third Floor Cardiology A3107
Los Angeles, CA 90048
Phone+1 310-248-8310

Fax+1 310-248-8338
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Education & Training

UCLA David Geffen School of Medicine/UCLA Medical CenterFellowship, Cardiovascular Disease, 1984 - 1986
UCLA David Geffen School of Medicine/UCLA Medical CenterResidency, Internal Medicine, 1980 - 1983
Icahn School of Medicine at Mount SinaiClass of 1980
Stanford UniversityB.S., 1972 - 1976

Certifications & Licensure

CA State Medical License 1981 - 2024
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Cardiovascular Disease

Awards, Honors, & Recognition

Fellow (FAHA) American Heart Association
Fellow (FACC) American College of Cardiology
Co-Chair, Thoracic Community of Practice Committee American Society for Transplantation
Past President International Society for Heart and Lung Transplantation
Past Chair American College Cardiology, Heart Failure and Transplantation Committee
Past Member UNOS National Thoracic Committee
Executive Program Committee World Transplant Congress, 2014
America's Top Doctors Castle Connolly, 2002-2014
Top Doctors:LA Area Castle Connolly, 2013
Top Doctors:Southern California Castle Connolly, 2012
CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2012-2013
Top MD Consumers Checkbook
Super Doctor SuperDoctors.com
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Clinical Trials

A Study to Compare the Effectiveness of a Drug That Suppresses the Immune System Called Thymoglobulin® in Preventing the Development of a Disease That Affects the Majority of Heart Transplant Recipients Called Cardiac Allograft Vasculopathy (CAV) Start of enrollment: 2010 Nov 01
Withdrawn
Phase 3
Home Electrocardiogram (ECG) Monitoring After Heart Transplantation Start of enrollment: 2011 Aug 01
Completed
Heartsbreath Test for Heart Transplant Rejection Start of enrollment: 2010 Dec 01
Unknown status
A Pivotal Trial to Establish the Efficacy and Long-term Safety of the Parachute Implant System Start of enrollment: 2012 Dec 01
Terminated
Phase 3
Safety and Efficacy of Desensitization Therapy in Sensitized Participants Awaiting Heart Transplantation Start of enrollment: 2013 Jun 01
Terminated
Phase 2
Diagnostic and Therapeutic Applications of Microarrays in Heart Transplantation Start of enrollment: 2016 Jan 01
Recruiting
The Effect and Safety Profile of Thymoglobulin® in Primary Cardiac Transplant Recipients Start of enrollment: 2018 Sep 13
Enrolling by invitation
Phase 2
Tocilizumab in Cardiac Transplantation Start of enrollment: 2018 Dec 20
Active, not recruiting
Phase 2
Trifecta-Heart cfDNA-MMDx Study Start of enrollment: 2021 Jun 01
Recruiting
Roles: Principal Investigator
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Publications & Presentations

PubMed

Redefining the molecular rejection states in 3230 heart transplant biopsies: relationships to parenchymal injury and graft survival.
Philip F Halloran, Katelynn Madill-Thomsen, Arezu Z Aliabadi-Zuckermann, Martin Cadeiras, Marisa G Crespo-Leiro, Eugene C Depasquale, Mario Deng, Johannes Gökler, Shel...> ;American Journal of Transplantation. 2024 Mar 23
Summary of a consensus conference on heart-liver transplantation.
Chen, S., Kobashigawa, J., VanWagner, L., Hall, S., Emamaullee, J., Entwistle, J., Ganger, D., Gebel, H., Jeevanandam, V., Kaldas, F., Kilic, A., Kittleson, M., Kushwa...> ;American Journal of Transplantation. 2024 Mar 1
1 citations
Temporal Trends, Risk Factors, and Clinical Outcomes of De Novo Lymphoproliferative Disorders After Heart Transplantation.
Kim, I., Kim, S., Youn, J., Kim, D., Lee, S., Kim, H., Kim, J., Jung, M., Cherikh, W., Rossano, J., Kobashigawa, J., Stehlik, J.> ;JACC. Heart Failure. 2024 Feb 1
Coronary Vasospasm Causing Chest Pain in Early Postoperative Heart Transplantation.
Le, J., Chang, D., Kobashigawa, J., Kittleson, M.> ;JACC. Case Reports. 2023 Dec 20
1 citations
Molecular states associated with dysfunction and graft loss in heart transplants.
Halloran, P., Madill-Thomsen, K., Mackova, M., Aliabadi-Zuckermann, A., Cadeiras, M., Crespo-Leiro, M., Depasquale, E., Deng, M., Gökler, J., Hall, S., Kim, D., Kobash...> ;The Journal of Heart and Lung Transplantation. 2024 Mar 1
Assessing and managing frailty in advanced heart failure: An International Society for Heart and Lung Transplantation consensus statement.
Denfeld, Q., Jha, S., Fung, E., Jaarsma, T., Maurer, M., Reeves, G., Afilalo, J., Beerli, N., Bellumkonda, L., De Geest, S., Gorodeski, E., Joyce, E., Kobashigawa, J.,...> ;The Journal of Heart and Lung Transplantation. 2023 Nov 29
Does bortezomib influence pre-transplant desensitization therapy or benefit post-heart transplant outcomes for highly sensitized patients?
Manvir Dhillon, Jon A Kobashigawa, Michelle Kittleson, Rashmi Jain, Nikhil Patel, Tahli Singer-Englar, Xiaohai Zhang, Matthew Hakimi, Tamar Aintablian, Robert Vescio, ...> ;Clinical Transplantation. 2024 Jan 1
HLA sensitization is associated with an increased risk of primary graft dysfunction after heart transplantation.
Jiho Han, Josh Rushakoff, Yasbanoo Moayedi, Erik Henricksen, Roy Lee, Helen Luikart, Omar Shalakhti, Loren Gragert, Lillian Benck, Darren Malinoski, Jon Kobashigawa, J...> ;The Journal of Heart and Lung Transplantation. 2024 Mar 1
IgM marks persistent IgG anti-human leukocyte antigen antibodies in highly sensitized heart transplant patients.
Fang Li, Loren Gragert, D Giovanni Biagini, Jignesh K Patel, Jon A Kobashigawa, Johannes Trück, Oscar Rodriguez, Corey T Watson, David R Gibb, Xiaohai Zhang, Evan P Kr...> ;The Journal of Heart and Lung Transplantation. 2024 Feb 1
1 citations
Heart transplantation in patients from socioeconomically distressed communities.
Qiudong Chen, Jad Malas, Dominic Emerson, Dominick Megna, Pedro Catarino, Fardad Esmailian, Joanna Chikwe, Lawrence S Czer, Jon A Kobashigawa, Michael E Bowdish> ;The Journal of Heart and Lung Transplantation. 2024 Feb 1
Wild-Type Transthyretin Cardiac Amyloidosis in a Transplanted Heart.
Lily K Stern, Pamela A Ivey, Corey J Lum, Shayaan Zaidi, Daniel Luthringer, Angela Velleca, Jon A Kobashigawa, Jignesh K Patel, Michelle M Kittleson> ;JACC. Case Reports. 2023 Aug 2
Complex Calculus-Older Donors for Older Heart Transplant Recipients?
Andriana P Nikolova, Jon A Kobashigawa> ;The Annals of Thoracic Surgery. 2023 Sep 1
27 citations
Intermediate-term outcomes of complement inhibition for prevention of antibody-mediated rejection in immunologically high-risk heart allograft recipients.
Guillaume Coutance, Jon A Kobashigawa, Evan Kransdorf, Alexandre Loupy, Eva Desiré, Michelle Kittleson, Jignesh K Patel> ;The Journal of Heart and Lung Transplantation. 2023 Oct 1
Reply to Comment on "Detection and management of HLA sensitization in candidates for adult heart transplantation".
Ersilia M DeFilippis, Evan P Kransdorf, Abhishek Jaiswal, Jignesh Patel, Jon A Kobashigawa, David A Baran, Michelle M Kittleson> ;The Journal of Heart and Lung Transplantation. 2023 Oct 1
Three year post heart transplant outcomes of desensitized durable mechanical circulatory support patients.
Jong-Chan Youn, Darae Kim, Mi-Hyang Jung, Jin-Jin Kim, In-Cheol Kim, Hye Sun Lee, Jin-Oh Choi, Eun-Seok Jeon, Keith Nishihara, Osamu Seguchi, Evan P Kransdorf, David H...> ;The Journal of Heart and Lung Transplantation. 2023 Oct 1
Successful Reuse of a Donor Heart.
Gabriel Esmailian, Qiudong Chen, Danny Ramzy, Jon A Kobashigawa, Joanna Chikwe, Fardad Esmailian> ;Texas Heart Institute Journal. 2023 May 1
2 citations
Heart retransplant recipients with renal dysfunction benefit from simultaneous heart-kidney transplantation.
Jad Malas, Qiudong Chen, Dominic Emerson, Dominick Megna, Pedro Catarino, Lawrence Czer, Jignesh Patel, Michelle Kittleson, Jon Kobashigawa, Joanna Chikwe, Michael E B...> ;The Journal of Heart and Lung Transplantation. 2023 Aug 1
1 citations
Simultaneous heart-kidney transplant in patients with borderline estimated glomerular filtration rate without dialysis dependency.
Qiudong Chen, Jad Malas, Kevin Gianaris, Gabriel Esmailian, Dominic Emerson, Dominick Megna, Pedro Catarino, Lawrence Czer, Michael E Bowdish, Joanna Chikwe, Jignesh P...> ;Clinical Transplantation. 2023 Aug 1
How to Approach HLA Sensitization in Heart Transplant Candidates.
Roopa A Rao, Evan P Kransdorf, Jignesh K Patel, Jon A Kobashigawa, Michelle M Kittleson> ;JACC. Heart Failure. 2023 Apr 1
Guidelines and principles for the care of the cardiothoracic transplant patient in the intensive care unit.
Michael Nurok, Mark E Nunnally, Michael O'Connor, Richard N Pierson 3rd, David A Baran, Michael D Harper, Darren Malinoski, Aly El Banayosy, Abiodun Orija, Shelley Hal...> ;Clinical Transplantation. 2023 Jun 1
7 citations
The evolving use of biomarkers in heart transplantation: Consensus of an expert panel.
Jon Kobashigawa, Shelley Hall, Palak Shah, Barry Fine, Phil Halloran, Annette M Jackson, Kiran K Khush, Kenneth B Margulies, Maryam Mojarrad Sani, Jignesh K Patel, Nik...> ;American Journal of Transplantation. 2023 Jun 1
9 citations
Addressing sex-based disparities in solid organ transplantation in the United States - a conference report.
Deirdre Sawinski, Jennifer C Lai, Sean Pinney, Alice L Gray, Annette M Jackson, Darren Stewart, Deborah Jo Levine, Jayme E Locke, James J Pomposelli, Matthew G Hartwig...> ;American Journal of Transplantation. 2023 Mar 1
3 citations
Temporary Mechanical Circulatory Support in Patients with Cardiogenic Shock: Clinical Characteristics and Outcomes.
Michael Abiragi, Tahli Singer-Englar, Robert M Cole, Dominic Emerson, Fardad Esmailian, Dominick Megna, Jaime Moriguchi, Jon A Kobashigawa, Michelle M Kittleson> ;Journal of Clinical Medicine. 2023 Feb 17
1 citations
Blood Type A1 Mismatch Does Not Affect Heart Transplant Outcomes at One Year.
Seongkyu Kim, Ellen Klapper, Jon A Kobashigawa, Michelle M Kittleson, Cao, L.> ;Journal of Clinical Medicine. 2023 Feb 8
1 citations
A survey of intensive care unit models in cardiothoracic transplantation at high-volume centers.
Michael Nurok, Mark E Nunnally, George Gill, Michael O'Connor, Michael Harper, Jeffrey Edelman, Abiodun Orija, Aly El Banayosy, Darren Malinoski, Thor Sundt, David A B...> ;Clinical Transplantation. 2023 Apr 1
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Journal Articles

Omission of Heart Transplant Recipients from the Appropriate Use Criteria for Revascularization and the Ramifications on Heart Transplant Centers
Jon A Kobashigawa, Steven W Tabak, Wendy Book, John A Spertus, JAMA Cardiology
Non‐Invasive Detection of Graft Injury After Heart Transplantation Using Donor‐Derived Cell‐Free DNA: A Prospective Multi‐Center Study
Gregory Ewald, Jon Kobashigawa, Kiran K Khush, Jignesh Patel, Eugene DePasquale, Sean Pinney, American journal of transplantation
Oxford University Press Has Registered This DOI Pre-Publication
Michelle Kittleson, Heidi Reich, Lawrence Czer, Dominick Megna, Jignesh Patel, Fardad Esmailian, Jon Kobashigawa, Oxford University Press
Use of Durable Mechanical Circulatory Support on Outcomes of Heart–Kidney Transplantation
Jon A Kobashigawa, Jaime Moriguchi, Joshua L Chan, Francisco Arabia, Fardad Esmailian, Dominick Megna, Lawrence S Czer, Interactive CardioVascular and Thoracic Surgery
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Lectures

CAV at 50 What We Know and What We Don't
2019 ACC Scientific Session & Expo, New Orleans - 3/17/2019
State-of-the-Art Review Imaging in Heart Transplant Patients
Cedars Sinai Medical Center, Riverside, California - 9/15/2012

Authored Content

Omission of Heart Transplant Recipients from the Appropriate Use Criteria for Revascularization and the Ramifications on Heart Transplant CentersApril 2020
Temporal Trends of De Novo Malignancy Development After Heart TransplantationJanuary 2018
Temporal Trends of De Novo Malignancy Development After Heart TransplantationJanuary 2018
Temporal Trends of De Novo Malignancy Development After Heart TransplantationJanuary 2018
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Press Mentions

Smidt Heart Institute Experts Available for Interviews During ISHLT ConferenceApril 18th, 2023
ISHLT Honors Jon Kobashigawa for Lifetime Achievement in Treating Advanced Heart DiseaseFebruary 15th, 2023
Upcoming Life Sciences EventsMay 3rd, 2022
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