JonLeslieRuckleMD

PubMed

• 11 citations
  First-in-human randomized clinical trials of the safety and efficacy of tanezumab for treatment of chronic knee osteoarthritis pain or acute bunionectomy pain.
  Patricia Ann Walicke, Franz F. Hefti, Roxanne Bales, Shiao-Ping Lu, Jon L Ruckle, Mark T. Brown, Christine R. West, David L. Shelton> ;Pain Reports. 2018 May 9
• 5 citations
  Pharmacokinetics and Pharmacodynamics of Anacetrapib Following Single Doses in Healthy, Young Japanese and White Male Subjects
  Rajesh Krishna, Ferdous Gheyas, Yang Liu, Josee Cote, Omar F Laterza, Jon L. Ruckle, John A. Wagner, Andrew Denker> ;Journal of Clinical Pharmacology. 2018 Feb 1
• 26 citations
  Phase-0/microdosing studies using PET, AMS, and LC-MS/MS: a range of study methodologies and conduct considerations. Accelerating development of novel pharmaceuticals ...
  Tal Burt, Christy S. John, Jon L Ruckle, Le T. Vuong> ;Expert Opinion on Drug Delivery. 2017 May 1
• 91 citations
  BPS804 Anti-Sclerostin Antibody in Adults With Moderate Osteogenesis Imperfecta: Results of a Randomized Phase 2a Trial.
  Francis H. Glorieux, Jean-Pierre Devogelaer, Michaela Durigova, Stefan Goemaere, Sarah Hemsley, Franz Jakob, Uwe Junker, Jon Ruckle, Lothar Seefried, Peter J Winkle> ;Journal of Bone and Mineral Research. 2017 Jul 1
• 37 citations
  Safety and Pharmacokinetics of the Anti-Orthopoxvirus Compound ST-246 following a Single Daily Oral Dose for 14 Days in Human Volunteers
  Jarasvech Chinsangaram, Kady M. Honeychurch, Shanthakumar R. Tyavanagimatt, Janet M. Leeds, Tove' C. Bolken, Kevin F. Jones, Robert Jordan, Thomas Marbury, Jon L. Ruck...> ;Antimicrobial Agents and Chemotherapy. 2012 Sep 1
• 47 citations
  Lycopene bioavailability and metabolism in humans: an accelerator mass spectrometry study
  Alastair B. Ross, Le Thuy Vuong, Jon L. Ruckle, Hans-Arno Synal, Tim Schulze-König, Karin Wertz, Robert Rümbeli, Rosa G. Liberman, Paul L. Skipper, Steven R. Tannenbau...> ;The American Journal of Clinical Nutrition. 2011 Jun 1
• 27 citations
  Evaluation of pharmacokinetic parameters and dipeptidyl peptidase-4 inhibition following single doses of sitagliptin in healthy, young Japanese males
  Gary A. Herman, Goutam C. Mistry, Bingming Yi, Arthur J. Bergman, Amy Qiu Wang, Wei Zeng, Li Chen, Karen Snyder, Jon L. Ruckle, Patrick Larson, Michael J. Davies, Rona...> ;British Journal of Clinical Pharmacology. 2011 Mar 1
• 14 citations
  Contribution of a Heating Element to Topical Anesthesia Patch Efficacy Prior to Vascular Access: Results From Two Randomized, Double-Blind Studies
  Salman Masud, Richard D. Wasnich, Jon L. Ruckle, William T. Garland, Stephen W. Halpern, Denis Mee-Lee, Michael A. Ashburn, John C. Campbell> ;Journal of Pain and Symptom Management. 2010 Oct 1
• 4 citations
  Effects of Laropiprant, a Selective Prostaglandin D2 Receptor 1 Antagonist, on the Pharmacokinetics of Rosiglitazone
  Jules I. Schwartz, Mark Stroh, Bing Gao, Fang Liu, Kimberly Rosko, Stefan Zajic, Alan J. Meehan, Jon L. Ruckle, Eseng Lai, John A. Wagner> ;Cardiovascular Therapeutics. 2009 Dec 1
• 164 citations
  Single‐Dose, Randomized, Double‐Blind, Placebo‐Controlled Study of ACE‐011 (ActRIIA‐IgG1) in Postmenopausal Women
  Jon Ruckle, Mark Jacobs, William Kramer, Amelia E. Pearsall, Ravindra Kumar, Kathryn W. Underwood, Jasbir Seehra, Yijun Yang, Carolyn H. Condon, Matthew L. Sherman> ;Journal of Bone and Mineral Research. 2009 Apr 1
• 31 citations
  Use of Accelerator Mass Spectrometry to Measure the Pharmacokinetics and Peripheral Blood Mononuclear Cell Concentrations of Zidovudine
  Le T. Vuong, Jon L. Ruckle, Arlin B. Blood, Michael J. A. Reid, Richard D. Wasnich, Hans-Arno Synal, Stephen R. Dueker> ;Journal of Pharmaceutical Sciences. 2008 Jul 1
• 30 citations
  Phase 1 trial of 13‐valent pneumococcal conjugate vaccine in Japanese adults
  Daniel A. Scott, Jon Ruckle, Marilyn Dar, Sherryl Baker, Hiroaki Kondoh, Stephen Lockhart> ;Pediatrics International. 2008 Jun 1
• 30 citations
  Anticholinesterase and pharmacokinetic profile of phenserine in healthy elderly human subjects.
  Nigel H. Greig, Jon Ruckle, Patrick Comer, Lidia Brownell, Harold W. Holloway, Douglas R. Flanagan, Craig J. Canfield, Robert G. Burford> ;Current Alzheimer Research. 2005 Sep 30
• 12 citations
  Multiple-dose pharmacokinetics of Fluvoxamine in children and adolescents
  Michael J. Labellarte, Joseph Biederman, Graham J. Emslie, James J. Ferguson, Arifulla Khan, Jon Ruckle, Randy Sallee, Mark A. Riddle> ;Journal of the American Academy of Child and Adolescent Psychiatry. 2004 Dec 1
• 22 citations
  Safety and pharmacokinetic profile of multiple escalating doses of (+)-calanolide A, a naturally occurring nonnucleoside reverse transcriptase inhibitor, in healthy HI...
  David A. Eiznhamer, Terri Creagh, Jon L. Ruckle, Dwain T. Tolbert, Jeremy Giltner, Bipul Dutta, Michael T. Flavin, Tuah R. Jenta, Ze-Qi Xu> ;HIV Clinical Trials. 2002 Nov 1
• 59 citations
  Safety and Pharmacokinetics of Single Doses of (+)-Calanolide A, a Novel, Naturally Occurring Nonnucleoside Reverse Transcriptase Inhibitor, in Healthy, Human Immunode...
  Terri Creagh, Jon L. Ruckle, Dwain T. Tolbert, Jeremy Giltner, David A. Eiznhamer, Bipul Dutta, Michael T. Flavin, Ze-Qi Xu> ;Antimicrobial Agents and Chemotherapy. 2001 May 1
• 76 citations
  Pharmacokinetics of repaglinide in subjects with renal impairment.
  Thomas Marbury, Jon L. Ruckle, Vibeke Hatorp, Michael P. Andersen, Karin Kramer Nielsen, Won Chin Huang, Poul Strange> ;Clinical Pharmacology and Therapeutics. 2000 Jan 1
• 17 citations
  A comparison of the pharmacokinetics and tolerability of the novel antimigraine compound zolmitriptan in adolescents and adults
  Ruth Dixon, Kurt Engleman, John D. Kemp, Jon L. Ruckle> ;Journal of Child and Adolescent Psychopharmacology. 1999 Jan 1
• 1 citations
  Depression. Management techniques in primary care.
  Frederick W. Silver, Jon L. Ruckle> ;Postgraduate Medicine. 1989 Mar 1
• The combination of insulin-like growth factor I and insulin-like growth factor-binding protein-3 reduces insulin requirements in insulin-dependent type 1 diabetes: evi...
  Clemmons, D. R., Moses, A. C., McKay, M. J., Sommer, A., Rosen, D. M., Ruckle, J.> ;J Clin Endocrinol Metab. 2000 Apr
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