JonathanSethJaffeMD

PubMed

• Summative Usability Evaluation of the SCTE-AI Device: A Novel Prefilled Autoinjector for Subcutaneous Testosterone Administration
  Jonathan S Jaffe, Samir Arora, Jed C Kaminetsky> ;The Journal of Sexual Medicine.
• A 52-Week Study of Dose-Adjusted Subcutaneous Testosterone Enanthate in Oil Self-Administered via Disposable Auto-Injector
  Ronald S Swerdloff, Andrew McCullough, Jed C Kaminetsky, Kathleen Hwang, Jonathan S Jaffe> ;The Journal of Urology.
• 27 citations
  Pharmacokinetic Profile of Subcutaneous Testosterone Enanthate Delivered via a Novel, Prefilled Single-Use Autoinjector: A Phase II Study.
  Kaminetsky, J., Jaffe, J. S., Swerdloff, R. S.> ;Sexual medicine. 2016 Jan 23
• Response to: ‘Is there a direct relationship between serum level of methotrexate and clinical efficacy and tolerability?’ by Fleishman and Yazici
  Michael Schiff, Jonathan S Jaffe, Bruce Freundlich> ;Annals of the Rheumatic Diseases. 2014 Sep 1
• 4 citations
  In response to dosing omalizumab in allergic asthma
  Jonathan S. Jaffe, Marc Massanari> ;The Journal of Allergy and Clinical Immunology. 2007 Jan 1
• 47 citations
  Human lung mast cell IL-5 gene and protein expression: temporal analysis of upregulation following IgE-mediated activation.
  Jonathan S. Jaffe, Mark C. Glaum, Donald G. Raible, Thomas J. Post, Edward Dimitry, Dinesh Govindarao, Yihe Wang, Edward S. Schulman> ;American Journal of Respiratory Cell and Molecular Biology. 1995 Dec 1
• 62 citations
  Evidence for an abnormal profile of interleukin-4 (IL-4) IL-5, and γ-interferon (γ-IFN) in peripheral blood T cells from patients with allergic eosinophilic gastroente...
  Jonathan S. Jaffe, Stephen P. James, Gerard E. Mullins, Lorenz Braun-Elwert, Irina A. Lubensky, Dean D. Metcalfe> ;Journal of Clinical Immunology. 1994 Sep 1
• 57 citations
  Functional abnormalities of CD8+ T cells define a unique subset of patients with common variable immunodeficiency.
  Jonathan S. Jaffe, Warren Strober, Michael C. Sneller> ;Blood. 1993 Jul 1
• 41 citations
  Reduced Interleukin-2 (IL-2) Production in Common Variable Immunodeficiency Is Due to a Primary Abnormality of CD4+ T Cell Differentiation
  Eli M. Eisenstein, Jonathan S. Jaffe, Warren Strober> ;Journal of Clinical Immunology. 1993 Jul 1
• 141 citations
  New Insights into Common Variable Immunodeficiency
  Michael C. Sneller, Warren Strober, Eli M. Eisenstein, Jonathan S. Jaffe, Charlotte Cunningham-Rundles> ;Annals of Internal Medicine. 1993 May 1
• 227 citations
  A novel lymphoproliferative/autoimmune syndrome resembling murine lpr/gld disease.
  Michael C. Sneller, Sharon E. Straus, Elaine S. Jaffe, J. S. Jaffe, Thomas A. Fleisher, Maryalice Stetler-Stevenson, Warren Strober> ;The Journal of Clinical Investigation. 1992 Aug 1
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Journal Articles

• Head-to-head, randomised, crossover study of oral versus subcutaneous methotrexate in patients with rheumatoid arthritis: drug-exposure limitations of oral methotrexat...  
  Schiff MH, Jaffe JS, Freundlich B, Ann Rheum Dis, 4/12/2014
• In response to dosing omalizumab in allergic asthma  
  Jonathan S. Jaffe, Marc Massanari, The Journal of Allergy and Clinical Immunology, 1/1/2007
• Everolimus and reduced-exposure cyclosporine in de novo renal-transplant recipients: a three-year phase II, randomized, multicenter, open-label study  
  Nashan B, Curtis J, Ponticelli C, Mourad G, Jaffe J, Haas T, 156 Study Group, Transplantation, 11/15/2004
• Effects of sirolimus on plasma lipids, lipoprotein levels, and fatty acid metabolism in renal transplant patients  
  Morrisett JD, Abdel-Fattah G, Hoogeveen R, Mitchell E, Ballantyne CM, Henry J. Pownall HJ, Opekun AR, Jaffe JS, Oppermann S, Kahan BD, J. Lipid Res., 1/1/2002
• Effect of sirolimus on the metabolism of apoB100- containing lipoproteins in renal transplant patients  
  Hoogeveen RC. Ballantyne CM. Pownall HJ. Opekun AR. Hachey DL. Jaffe JS. Oppermann S. Kahan BD. Morrisett JD, Transplantation, 10/15/2001
• Hydrogen peroxide release from human eosinophils on fibronectin: scopoletin enhances eosinophil activation  
  Raible DG, Mohanty JG, Jaffe JS, Stella HJ, Sprenkle BE, Glaum MC, Schulman ES, Free Radic Biol Med, 6/1/2000
• Sirolimus in pediatric gastrointestinal transplantation: The use of sirolimus for pediatric patients with tacrolimus-related cardiomyopathy  
  Pappas PA, Weppler D, Pinna AD, Rusconi P, Thompson JF, Jaffe JS, Tzakis AG, Pediatr Transplantation, 2/1/2000
• Stimulated response of peripheral lymphocytes may distinguish cyclosporine effect in renal transplant recipients receiving a cyclosporine and rapamycin regimen  
  Sindhi R, LaVia MF, Paulling E, McMichael JM, Burckhart G, Shaw S, Sindhi LA, Livingston R, Sehgal S, Jaffe J, Transplantation, 2/1/2000
• Cytokine mRNA expression in human platelets and a megakaryocytic cell line and cytokine modulation of platelet function  
  Soslau G. Morgan DA. Jaffe JS. Brodsky I. Wang Y, Cytokine, 6/1/1997
• A highly sensitive fluorescent micro-assay of H2O2 release from activated human leukocytes using a dihydroxyphenoxazine derivative  
  Mohanty JG. Jaffe JS. Schulman ES. Raible DG, Journal of Immunological Methods, 3/28/1997
• Human Lung Mast Cell Activation Leads to IL-13 mRNA Expression and Protein Release  
  Jaffe JS, Raible DG, Post TJ, Wang Y, Glaum MC, Butterfield JH, Schulman ES, Am J Resp Cell and Mol Biol, 10/1/1996
• Differential usage of T-cell receptor V beta gene families by CD4+ and CD8+ T Cells in patients with CD8hi common variable immunodeficiency: evidence of a post-thymic ...  
  Duchmann R, Jaffe J, Ehrhardt R, Alling DW, Strober W, Immunology, 1/1/1996
• IgE-mediated Interleukin-5 Generation by Human Lung Fragments and Mast Cells  
  Jaffe JS, Glaum MC, Raible DG, Post TJ, Dimitry E, Govindarao D, Wang Y, Schulman ES, Am J Resp Cell and Mol Biol, 12/1/1995
• IgE-Dependent expression of IL-5 mRNA and protein in human lung: modulation by dexamethasone  
  Glaum MG, Jaffe JS, Gillespie DH, Raible DG, Post TJ, Wang Y, Dimitry E, Schulman ES, Clin Immunol Immunopathol, 5/1/1995
• Evidence for an abnormal profile of IL-4, IL-5, and gamma-IFN in peripheral blood T cells from patients with allergic eosinophilic gastroenteritis  
  Jaffe JS, James SP, Mullins GE, Lubensky I and Metcalfe DD, J Clin Immunol, 9/1/1994
• Abnormal cytokine expression in Sezary and adult T-cell leukemia cells correlates with the biologic diversity between these T-cell malignancies  
  Tendler CL, Burton JB, Jaffe J, Danielpour D, Charley M, McCoy JP, Pittelkow MR, Waldmann TA, Cancer Research, 8/15/1994
• Acute bronchospasm Caused by Sulfites  
  Szema AM, Lang DM, Jaffe JS, Contemporary Internal Medicine, 1/1/1994
• Cytokines and their role in the pathogenesis of severe food hypersensitivity reactions  
  Jaffe JS and Metcalfe DD, Ann Allergy, 10/1/1993
• Functional abnormalities of CD8+ T cells define a unique subset of patients with common variable immunodeficiency  
  Jaffe JS, Strober WS, and Sneller MC, Blood, 7/1/1993
• Impaired CD4+ T lymphocytes in of patients with common variable immune deficiency  
  Eisenstein EM, Jaffe JS, and Strober WS, J Clin Immunol, 7/1/1993
• RT-PCR with affinity captured mRNA  
  Cuddy K, Foley B, Jaffe JS, Gillespie D, Nucleic Acids Res., 5/11/1993
• Abnormalities of CD8+ T-cell function in a subgroup of patients with common variable immunodeficiency, pp 726-727 In: Sneller MC, moderator New insights into common...  
  Jaffe JS, Ann Intern Med, 5/1/1993
• T-cell abnormalities in common variable immunodeficiency  
  Jaffe JS, Eisenstein EM, Sneller MC and Strober W, Pediatric Research, 1/1/1993
• A novel lymphoproliferative/autoimmune syndrome resembling murine lpr/gld disease  
  Sneller MC, Straus SE, Jaffe ES, Jaffe JS, Fleisher TA, Stetler-Stevenson M and Strober W, J Clin Invest, 8/1/1992
• Beneficial Actions of Nalorphine During Hemorrhagic Shock in Cats  
  Hock CE, Curtis MT, Jaffe JS, Lefer AM, Proceedings of the Society for Experimental Biology and Medicine, 5/1/1983
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Abstracts/Posters

• A liquid formulation of omalizumab is bioequivalent to the current lyophilized formulation.
  G-J Riviere, P Kuebler, J. Jaffe, C. M Yeh, C. Reynolds L. Brookman, AJRCCM, 1/1/2008
• The Effect of Discontinuing Omalizumab Therapy on Free IgE Concentration.
  P. Lowe, J. Jaffe, C. Martin, L. Brookman, H. Fox, The Journal of Allergy and Clinical Immunology, 1/1/2007
• Everolimus In De Novo Pediatric Renal Transplantation: Results At 24 Months.
  R Ettenger , V M Moeller, P F Hoyer, J Lemire , J Mahan , N Webb , P Niaudet and J Jaffe, American Transplantation Congress, 1/1/2004
• 36 Month Results With Everolimus (E) In Liver Transplantation.
  G. Levy, V. M. Moeller, J. Jaffe, J. Punch, P. Neuhaus, D. Mayer, American Transplantation Congress, 1/1/2004
• 24 Month Safety Results Of A Randomized, Multicenter, Double-Blind Study Of Everolimus Vs Azathioprine In De Novo Heart Transplant Recipients.
  H. Eisen, J. Kobashigawa, R. C. Starling, N. Cretin, J. Jaffe, J. Murphy, American Transplantation Congress, 1/1/2004
• A Multi-Center, Randomized, Placebo-Controlled, Double-Blind, Parallel Group, Dose-Finding Study To Evaluate The Safety, Tolerability And Pharmacokinetics Of Everolimu...
  Gary Levy, Virginia Moeller, Jonathan Jaffe, Jeffrey Punch, David Mayer, Peter Neuhaus, American Transplantation Congress, 1/1/2004
• Favorable Effect Of Everolimus On Cardiac Allograft Vasculopathy Is Maintained Through 24 Months.
  E. M. Tuzcu, J. A. Kobashigawa, H. J. Eisen, R. C. Starling, T. Crowe, K. Abeywickrama, J. Jaffe., American Transplantation Congress, 1/1/2004
• Risk Factors For Acute Rejection And Vasculopathy Among 634 Patients Treated With Everolimus Or Azathioprine.
  R. C. Starling, J. Kobashigawa, H. Eisen, J. Jaffe, Y. Li, American Transplantation Congress, 1/1/2004
• Sirolimus Does Not Prevent Seroconversion In CMV Seronegative Recipients Of CMV Positive Kidneys.
  Pescovitz MD, Jaffe JS, Ekeland R, Brown J, ASTS 25th Annual Meeting; Transplantation, 5/19/1999
• Triglyceride Elevations in Renal Transplant Recipients Treated with Sirolimus (Rapamycin, RAPA) Added to a Cyclosporine/Prednisone Regimen.
  Kahan BD, Jaffe JS, ASTS 25th Annual Meeting; Transplantation, 5/19/1999
• Pharmacokinetic/Pharmacodynamic Profiles of African Americans in a Phase III Randomized Placebo-Controlled Trial of Sirolimus (RAPA) in Renal Transplantation.
  Sindhi R, Jaffe J, Caulfield M, ASTS 25th Annual Meeting; Transplantation, 5/19/1999
• Effect of Sirolimus on Plasma Lipid and Lipoprotein Levels and Metabolism In Renal Transplant Patients.
  Morrisett JD, Ballentyne CM, Pownall HJ, Poekun AR Jaffe JS, Opperman S, Kahan BD, American Society of Transplantation 18th Annual Meeting, 5/1/1999
• Rapamycin (RAPA) Lowers Dose Requirements of Cyclosporine (CsA) In Renal Transplant Patients (RTX).
  Ahuja M, Jaffe JS, Bresnahan B, Adams MB, Johnson CP, Roza AM, Hariharan, American Society of Transplantation 18th Annual Meeting, 5/1/1999
• Effect Of Race On Efficacy And Safety Of Sirolimus Vs AZA And Standard Immunotherapy In Renal Transplantation.
  Neylan JF, Wickersham P, Jaffe J, American Society of Transplantation 18th Annual Meeting, 5/1/1999
• Outcomes Of African American In A Phase III Randomized Placebo-Controlled Trial Of Sirolimus In Renal Transplantation.
  Sindhi R, Wickersham PS, Jaffe JS, American Society of Transplantation 18th Annual Meeting, 5/1/1999
• Intracellular IL-2 Production In CD4 Lymphocytes Decreases Predictably In Renal Transplant Recipients Receiving Neoral At Peak (Cmax) Blood Concentrations.
  Sindhi R, Mariano FL, Shah J, Pauling E, Shaw S, Baliga PK, Rajagopalan PR, Livingston R, Jaffe J, ASN 17th Annual Meeting, Philadelphia, PA, 10/29/1998
• A Sensitive Fluorescent Micro-Assay Of H2O2 Release From Activated Human Leukocytes Using A Dihydroxyphenoxazine Derivative.
  Mohanty JG, Jaffe JS, Schulman ES, Raible DG, Inflammation Research Association International Conference, 1/1/1997
• Activated Human Lung Fragments And Human Mast Cells Synthesize IL-13.
  Jaffe JS, Wang Y, Post TJ, Glaum MC, Raible DG, Mohanty JG, Butterfield JH, Lang DM, Schulman ES, J. Allergy and Clin. Immunol., 1/1/1996
• Psychological comorbidity in asthma.
  Lang, DM, Sherman MS, Jaffe JS, Verdecchia S, Rutigliano PJ, Derogatis LR, J. Allergy and Clin. Immunol., 1/1/1996
• Propranolol enhances histamine and interleukin-5 generation from anti-IgE challenged human lung fragments: evidence for inverse agonist effect.
  Remy FJ, Jaffe JS, Raible DG, Post TJ, Wang Y,Glaum MC, Schulman ES, J. Allergy and Clin. Immunol., 1/1/1996
• Isoproterenol and Salmeterol-induced attenuation of interleukin-5 mRNA and protein from anti-IgE challenged human lung fragments.
  Remy FJ, Dimitry EA, Jaffe JS, Raible DG, Post TJ, Glaum M, Wang Y, Schulman ES, Am J Resp and Crit Care Med, 1/1/1995
• B-adrenergic agonist-induced attenuation of interleukin-5 mRNA and protein from anti-IgE challenged human lung fragments.
  Dimitry EA, Jaffe JS, Post TJ, Glaum M, Wang Y, Gillespie D, Schulman ES, Am J Resp and Crit Care Med, 1/1/1994
• IgE-dependent secretion of IL-5 by lung fragments and human lung mast cells.
  Jaffe JS, Schulman ES, Wang Y, J. Allergy and Clin. Immunol., 1/1/1994
• Cultured B cells and T cells from patients with common variable immunodeficiency lack evidence of viral infection.
  Eisenstein EM, Selvaggi TA, Jaffe JS, Goff J, Frenkel N, Wyatt L, Strober W, J. Allergy and Clin. Immunol., 1/1/1994
• Activation of human lung mast cells induces early expression of IL-5 mRNA, but not IL-3, IL-4 and GM-CSF.
  Jaffe JS, Schulman ES, Abstract-AAI/CIS meeting); J Immunol., 1/1/1993
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