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Office
1211 22nd Ave
Nashville, TN 37232Phone+1 615-936-2000Fax+1 615-936-0605- Is this information wrong?
Summary
- Dr. Jonathan Lehman is excited to join the extraordinary research and clinical faculty community at Vanderbilt University Medical Center in medical oncology. His clinical and research interests center on the treatment of thoracic malignancy, including small cell lung cancer (SCLC), the most aggressive lung carcinoma. Dr. Lehman is a physician-scientist and Harrison Society Scholar with a focus on neuroendocrine malignancy, tumor heterogeneity, and signaling. He has over a decade of research experience ranging from studying transgenic maize gene regulation at the USDA National Center for Agricultural Utilization Research (NCAUR) to genetically epilepsy prone rat models and vanadium peroxidase chemistry. He earned his MD and PhD from the University of Alabama School of Medicine at Birmingham, and his thesis work focused on the role of a novel organelle, the primary cilium, in the regulation of developmental pathways involving growth, cell migration, wound healing, and differentiation in the hair and skin. He brings his developmental biology background to novel target discovery and treatments in lung cancer including the biology of chemotherapy resistance in SCLC, as well as somatostatin receptor and neuroendocrine signaling. Dr. Lehman completed his residency in internal medicine and fellowship in medical oncology at Vanderbilt University Medical Center and is dedicated to improving the care and outcomes of lung cancer patients through basic and translational research. Dr. Lehman is a United States Department of Education Presidential Scholar, Congressional Barry M. Goldwater Scholar, 2015 American Society of Clinical Oncology (ASCO) Conquer Cancer Foundation Young Investigator, and 2016 LUNGevity Foundation Career Development Awardee.
Education & Training
Vanderbilt University Medical CenterFellowship, Hematology and Medical Oncology, 2012 - 2016- Vanderbilt University Medical CenterResidency, Internal Medicine, 2010 - 2012
University of Alabama School of MedicineClass of 2010
University of Alabama at BirminghamPhD, Cellular and Developmental Biology, 2002 - 2009
Certifications & Licensure
TN State Medical License 2015 - 2024- American Board of Internal Medicine Internal Medicine
- American Board of Internal Medicine Medical Oncology
Awards, Honors, & Recognition
- Harrison Society Scholar Vanderbilt University Medical Center
- LUNGevity Foundation Career Development Award LUNGevity, 2016
- Conquer Cancer Foundation Young Investigator Award American Society of Clinical Oncology, 2015
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Publications & Presentations
PubMed
- Integrated Multi-omics Analysis of Early Lung Adenocarcinoma Links Tumor Biological Features with Predicted Indolence or Aggressiveness.Maria-Fernanda Senosain, Yong Zou, Khushbu Patel, Shilin Zhao, Alexis Coullomb, Dianna J Rowe, Jonathan M Lehman, Jonathan M Irish, Fabien Maldonado, Michael N Kammer,...> ;Cancer Research Communications. 2023 Jul 1
- 8 citationsHLA-DR cancer cells expression correlates with T cell infiltration and is enriched in lung adenocarcinoma with indolent behaviorMaria-Fernanda Senosain, Yong Zou, Tatiana Novitskaya, Georgii Vasiukov, Aneri B. Balar, Dianna J. Rowe, Deon B. Doxie, Jonathan M. Lehman, Rosana Eisenberg, Fabien Ma...> ;Scientific Reports. 2021 Jul 13
- 34 citationsA Phase 1-2 Study of Rovalpituzumab Tesirine in Combination With Nivolumab Plus or Minus Ipilimumab in Patients With Previously Treated Extensive-Stage SCLC.Jyoti Malhotra, Petros Nikolinakos, Ticiana Leal, Jonathan M. Lehman, Daniel Morgensztern, Jyoti D. Patel, John Wrangle, Giuseppe Curigliano, Laurent Greillier, Meliss...> ;Journal of Thoracic Oncology. 2021 Feb 27
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Journal Articles
- Targeted therapy in small cell lung cancer: can DLL3 notch up a victory?Jonathan M Lehman, Leora Horn, Translational Cancer Research
Professional Memberships
- Member
- IASLC (International Association for the Study of Lung Cancer)Member
Hospital Affiliations
Vanderbilt University Medical CenterNashville, Tennessee
Tennessee Valley HCS - Nashville and MurfreesboroNashville, Tennessee
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