Jonathan Miner MD PhD

PubMed

• ArfGAP2 promotes STING proton channel activity, cytokine transit, and autoinflammation.
  Subhajit Poddar, Samuel D Chauvin, Christopher H Archer, Wei Qian, Jean A Castillo-Badillo
  Cell. 2025-03-20
• 3 citations
  The critical role of endoplasmic reticulum stress and the stimulator of interferon genes (STING) pathway in kidney fibrosis.
  Magaiver Andrade-Silva, Poonam Dhillon, Andrea Sanchez-Navarro, Dhanunjay Mukhi, Hailong Hu
  Kidney International. 2025-02-01
• Crizanlizumab for retinal vasculopathy with cerebral leukoencephalopathy in a phase II clinical study.
  Wilson X Wang, Dan Spiegelman, P Kumar Rao, Rennie L Rhee, Andria L Ford
  The Journal of Clinical Investigation. 2024-12-16

Journal Articles

• A Human Gain-of-Function STING Mutation Causes Immunodeficiency and Gammaherpesvirus-Induced Pulmonary Fibrosis in Mice  
  Jonathan Miner, MD, mBio
• Nitro-Fatty Acids Are Formed in Response to Virus Infection and Are Potent Inhibitors of STING Palmitoylation and Signaling  
  Katherine A Fitzgerald, Jonathan J Miner, Proceedings of the National Academy of Sciences
• HOIL1 is essential for the induction of type I and III interferons by MDA5 and regulates persistent murine norovirus infection  
  MacDuff DA, Baldridge MT, Qaqish AM, Nice TJ, Darbandi AD, Hartley VL, Peterson ST, Miner JJ, Iwai K, Virgin HW, J Virol, 1/1/2018
• A human gain-of-function STING mutation causes immunodeficiency and gammaherpesvirus-induced pulmonary fibrosis in mice  
  Bennion BG, Ingle H, Ai TL, Miner CA, Platt DJ, Smith AM, Baldridge MT, Miner JJ, J Virol, 1/1/2018
• Nitro-fatty acids are formed in response to virus infection and are potent inhibitors of STING palmitoylation and signaling  
  Hansen AL, Buchan GJ, Ruhl M, Mukai K, Salvatore SR, Ogawa E, Andersen SD, Iversen MB, Thielke AL, Gunderstofte C, Motwani M, Moller CT, Jakobsen AS, Fitzgerald KA, Ro..., PNAS, 1/1/2018
• A tropical virus that prefers cool weather  
  Miner JJ, Sci Transl Med, 1/1/2018
• Lessons learned from chikungunya in the Americas  
  Miner JJ and Lenschow DJ, Arthritis Rheumatol, 1/1/2018
• Apoptotic debris goes in the Bim  
  Miner JJ, Sci Transl Med, 1/1/2017
• Lurking culprits  
  Miner JJ, Sci Transl Med, 1/1/2017
• Consequences of congenital Zika virus infection  
  Platt DJ and Miner JJ, Curr Opin Virology, 1/1/2017
• Defeating Zika  
  Miner JJ, Sci Transl Med., 1/1/2017
• Wolbachia wallops Zika  
  Miner JJ, Sci Transl Med, 1/1/2017
• Mechanisms of restriction of viral neuroinvasion at the blood-brain barrier  
  Miner JJ, Diamond MS, Curr Opin Immunol, 1/1/2016
• Chikungunya viral arthritis in the United States: A mimic of seronegative rheumatoid arthritis  
  Miner JJ, Aw Yeang, HX, Fox JM, Taffner S, Malkov O, Oh ST, Kim AH, Diamond MS, Lenschow DJ, Yokoyama WM, Arthritis Rheumatol, 1/1/2015
• The TAM receptor Mertk protects against neuroinvasive viral infection by maintaining blood-brain barrier integrity  
  Miner JJ, Daniels BP, Shrestha B, Proenca-Modena JL, Lew ED, Lazear HM, Gorman MJ, Lemke G, Klein RS, and Diamond MS, Nature Med, 1/1/2015
• Management of rheumatologic disease  
  Miner JJ and Brasington RD, Washington Manual of Outpatient Int Med, 1/1/2015
• MDA5 and autoimmune disease  
  Miner JJ, Diamond MS, Nature Genet, 1/28/2014
• Cardiac manifestations of systemic lupus erythematosus  
  Miner JJ, Kim AH, Rheum Dis Clin N Amer, 1/1/2014
• Interferon regulatory factor 5 (IRF5)-dependent immune responses in the draining lymph node protect against West Nile virus infection  
  Thackray LB, Shrestha B, Richner JM, Miner JJ, Pinto AK, Lazear HM, Gale M Jr, Diamond MS, J Virol, 1/1/2014
• Core 1-derived O-glycans are essential E-selectin ligands on leukocytes  
  Yago T, Fu J, McDaniel JM, Miner JJ, McEver RP, Proc Natl Acad Sci, 1/1/2010
• Galectin-1 induces reversible phosphatidylserine exposure at the plasma membrane  
  Stowell SR, Karmakar S, Arthur CM, Ju T, Rodrigues LC, Riul TB, Dias-Baruffi M, Miner J, McEver RP, Cummings RD, Molec Biol Cell, 1/1/2009
• Separable requirements for cytoplasmic domain of PSGL-1 in leukocyte rolling and signaling under flow  
  Miner JJ, Xia L, Yago T, Kappelmayer J, Liu Z, Klopocki AG, Shao B, McDaniel JM, Setiadi H, Schmidtke DW, McEver RP, Blood, 1/1/2008
• Platelet glycoprotein Ib-alpha forms catch bonds with human WT vWF but not with type 2B von Willebrand disease vWF  
  Yago T, Lou J, Wu T, Yang J, Miner JJ, Coburn L, L�pez JA, Cruz MA, Dong JF, McIntire LV, McEver RP, Zhu C., J Clin Invest, 1/1/2008
• The discovery of aspirin's antithrombotic effects  
  Miner JJ, Hoffhines AJ, Texas Heart Inst J, 1/1/2007
• Join now to see all