Jonathan Paul Piccini Sr. MD

Cardiac Electrophysiology

Professor of Medicine, Director of Cardiac Electrophysiology; Duke Heart Center & Duke Clinical Research Institute, Duke University

Summary

Jonathan P. Piccini, MD, MHS, FACC, FAHA, FHRS is a clinical cardiac electrophysiologist and Professor of Medicine and Population Health at Duke University and the Duke Clinical Research Institute. He is the Director of the Cardiac Electrophysiology section at the Duke Heart Center. His focus is on the care of patients with atrial fibrillation and complex arrhythmias, with particular emphasis on catheter ablation, pacing, and lead extraction. His research interests include the development and evaluation of innovative cardiovascular interventions for the treatment of heart rhythm disorders. He serves on the Board of Trustees of the Heart Rhythm Society, is an Associate Editor at JACC: Clinical Electrophysiology, and is an elected member of the American Society for Clinical Investigation. Dr. Piccini has more than 600 publications in the field of heart rhythm medicine.

Duke University HospitalFellowship, Clinical Cardiac Electrophysiology, 2009 - 2011
Duke University HospitalFellowship, Cardiovascular Disease, 2005 - 2009
Johns Hopkins UniversityResidency, Internal Medicine, 2002 - 2005
Northwestern University The Feinberg School of MedicineClass of 2002

CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2013
Fellow (FACC) American College of Cardiology

PubMed

An External Control Arm for the Oral Factor XIa Inhibitor Asundexian Phase 2 Trial in Atrial Fibrillation (PACIFIC-AF) Using Electronic Health Records.
Tatsiana Vaitsiakhovich, Alexander Hartenstein, Stephen Privitera, Manesh R Patel, Jonathan P Piccini
Cardiology and Therapy. 2025-09-01
4 citations
Complications associated with pulsed field ablation vs radiofrequency catheter ablation of atrial fibrillation.
Min Soo Cho, So-Ryoung Lee, Eric Black-Maier, Kevin P Jackson, Daniel J Friedman
Heart Rhythm. 2025-09-01
2 citations
An international physician survey of current ablation practices in atrial fibrillation: An AIM-AF substudy.
Sanjeev Saksena, April Slee, Jose L Merino, Andreas Goette, Giuseppe Boriani
Heart Rhythm. 2025-09-01

Journal Articles

Focus on Transcatheter Aortic Valve Replacement Incidence, Management, and Associated Clinical Outcomes of New-Onset Atrial Fibrillation Following Transcatheter Aortic...
Jonathan P Piccini, Vinod H Thourani, Samir Kapadia, David Cohen, Eric Peterson, Matthew W Sherwood, Ajay Kirtane, Sreekanth Vemulapalli, Amit N Vora, Bhaskar Bhardwaj, ScienceDirect
Mineralocorticoid Receptor Antagonism for the Treatment of AF and HFpEF
Jonathan P Piccini, Adam D DeVore, ScienceDirect
Incremental Prognostic Value of Renal Function for Stroke Prediction in Atrial Fibrillation☆
Gregg C Fonarow, Kenneth W Mahaffey, Sean D Pokorney, Eric D Peterson, Jonathan P Piccini, International Journal of Cardiology
Original Research the Prognostic Value of Diastolic and Systolic Mechanical Left Ventricular Dyssynchrony Among Patients with Coronary Heart Disease
Zainab Samad, Peter R Liu, Marat Fudim, Jonathan P Piccini, ScienceDirect
Application of Net Reclassification Index to Non-Nested and Point-Based Risk Prediction Models: A Review
Laine E Thomas, Jonathan P Piccini, European Heart Journal
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PRAGUE-25: Ablation Improves Rhythm Control, but Don’t Discount Lifestyle ChangesJuly 14th, 2025
PRAGUE-25: What Is the Best Intervention Strategy for AFib in Obesity?July 1st, 2025
Studies Spotlight Safety Concerns with Pulsed-Field Ablation for AFMay 5th, 2025
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