
Jonathan Paul Piccini Sr. MD
Cardiac Electrophysiology
Professor of Medicine, Director of Cardiac Electrophysiology; Duke Heart Center & Duke Clinical Research Institute, Duke University
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40 Duke Medicine CirDurham, NC 27710
Phone+1 919-684-8111
Fax+1 919-668-7057
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Summary
- Jonathan P. Piccini, MD, MHS, FACC, FAHA, FHRS is a clinical cardiac electrophysiologist and Professor of Medicine at Duke University and the Duke Clinical Research Institute. He is the Director of the Cardiac Electrophysiology for the Duke University Health System. His focus is on the care of patients with atrial fibrillation and complex arrhythmias, with particular emphasis on catheter ablation, pacing, and lead extraction. His research interests include the development and evaluation of innovative cardiovascular interventions for the treatment of heart rhythm disorders. He is an Associate Editor at JACC: Clinical Electrophysiology and is an elected member of the American Society for Clinical Investigation. Dr. Piccini has more than 650 publications in the field of heart rhythm medicine.
Education & Training
Duke University HospitalFellowship, Clinical Cardiac Electrophysiology, 2009 - 2011
Duke University HospitalFellowship, Cardiovascular Disease, 2005 - 2009
Johns Hopkins UniversityResidency, Internal Medicine, 2002 - 2005
Northwestern University The Feinberg School of MedicineClass of 2002
Certifications & Licensure
NC State Medical License 2005 - 2026
American Board of Internal Medicine Cardiovascular Disease
American Board of Internal Medicine Clinical Cardiac Electrophysiology
Awards, Honors, & Recognition
- CMS Meaningful Use Stage 2 Certification EpicCare Ambulatory 2014 Certified EHR Suite, Epic Systems Corporation, 2013-2014, 2016-2017
- CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory 2014 Certified EHR Suite, Epic Systems Corporation, 2013-2014, 2016-2017
- CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory - Core EMR, Epic Systems Corporation, 2013-2014, 2016-2017
Clinical Trials
Publications & Presentations
PubMed
- Considerations for using atrial fibrillation burden as a surrogate endpoint: A report from the Cardiovascular Sciences Research Consortium.Krishna Pundi, Charu Gandotra, William Sanders, Fortunato Senatore, Jason G Andrade
American Heart Journal. 2026-11-01 - Atrial Fibrillation Ablation Effectiveness End Points, Safety End Points, and Trial Design: Academic Research Consortium Initiative Endorsed by the Heart Rhythm Society.Paul J Wang, Edward P Gerstenfeld, Jonathan P Piccini, Atul Verma, T Jared Bunch
Circulation. Arrhythmia and Electrophysiology. 2026-09-29 - 5 citationsStroke and systemic embolism following atrial fibrillation ablation: the EMBOL-AF Global Registry.Sergio Castrejón-Castrejón, Christian-Hendrik Heeger, Christian Veltmann, David Schaack, Moritz Nies
European Heart Journal. 2026-09-22
Journal Articles
- Focus on Transcatheter Aortic Valve Replacement Incidence, Management, and Associated Clinical Outcomes of New-Onset Atrial Fibrillation Following Transcatheter Aortic...Jonathan P Piccini, Vinod H Thourani, Samir Kapadia, David Cohen, Eric Peterson, Matthew W Sherwood, Ajay Kirtane, Sreekanth Vemulapalli, Amit N Vora, Bhaskar Bhardwaj, ScienceDirect
- Mineralocorticoid Receptor Antagonism for the Treatment of AF and HFpEFJonathan P Piccini, Adam D DeVore, ScienceDirect
- Incremental Prognostic Value of Renal Function for Stroke Prediction in Atrial Fibrillation☆Gregg C Fonarow, Kenneth W Mahaffey, Sean D Pokorney, Eric D Peterson, Jonathan P Piccini, International Journal of Cardiology
Press Mentions
STUN-AF: Ablation Before LAAO May Reduce Peridevice LeaksJuly 2nd, 2026
PRAGUE-25: Ablation Improves Rhythm Control, but Don’t Discount Lifestyle ChangesJuly 14th, 2025
PRAGUE-25: What Is the Best Intervention Strategy for AFib in Obesity?July 1st, 2025
Grant Support
- (1/2) Catheter Ablation Versus Antiarrhythmic and Heart Failure Drug Therapy in Preserved Ejection Fraction Heart Failure (CABANA-HF)IHC HEALTH SERVICES, INC.2026–2027
- Neurocognition and Greater Maintenance of Sinus Rhythm in AF (NOGGIN AF)DUKE UNIVERSITY2021–2026
Professional Memberships
- Member
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