JonathanTSimsMD

PubMed

• 86 citations
  Imatinib reverses doxorubicin resistance by affecting activation of STAT3-dependent NF-κB and HSP27/p38/AKT pathways and by inhibiting ABCB1.
  Jonathan T. Sims, Sourik S. Ganguly, Holly Bennett, J. Woodrow Friend, Jessica Tepe, Rina Plattner> ;Plos One. 2013 Jan 31
• 56 citations
  c-Abl and Arg are activated in human primary melanomas, promote melanoma cell invasion via distinct pathways, and drive metastatic progression
  Sourik S. Ganguly, Leann S. Fiore, Jonathan T. Sims, J W Friend, Divyamani Srinivasan, M A Thacker, Michael L. Cibull, Chi Wang, Marian Novak, David M. Kaetzel, Rina P...> ;Oncogene. 2012 Apr 5
• 42 citations
  Anaplasma phagocytophilum APH_0032 is expressed late during infection and localizes to the pathogen-occupied vacuolar membrane.
  Bernice Huang, Matthew J. Troese, Dale Howe, Shaojing Ye, Jonathan T. Sims, Robert A. Heinzen, Dori L. Borjesson, Jason A. Carlyon> ;Microbial Pathogenesis. 2010 Nov 1
• 33 citations
  Anaplasma phagocytophilum APH_1387 Is Expressed throughout Bacterial Intracellular Development and Localizes to the Pathogen-Occupied Vacuolar Membrane
  Bernice Huang, Matthew J. Troese, Shaojing Ye, Jonathan T. Sims, Nathan L. Galloway, Dori L. Borjesson, Jason A. Carlyon> ;Infection and Immunity. 2010 May 1
• 33 citations
  Enhanced Resistance to Tamoxifen by the c-ABL Proto-oncogene in Breast Cancer
  Huajun Zhao, Fu Ou-Yang, I-Fen Chen, Ming-Feng Hou, Shyng-Shiou F. Yuan, Hsueh-Ling Chang, Yi-Chen Lee, Rina Plattner, Susan E. Waltz, Shuk-Mei Ho, Jonathan T. Sims, S...> ;Neoplasia. 2010 Mar 1
• 25 citations
  STI571 sensitizes breast cancer cells to 5-fluorouracil, cisplatin and camptothecin in a cell type-specific manner
  Jonathan T. Sims, Sourik S. Ganguly, Leann S. Fiore, Christopher J. Holler, Eun-Sil Park, Rina Plattner> ;Biochemical Pharmacology. 2009 Aug 1
• 29 citations
  MTT assays cannot be utilized to study the effects of STI571/Gleevec on the viability of solid tumor cell lines.
  Jonathan T. Sims, Rina Plattner> ;Cancer Chemotherapy and Pharmacology. 2009 Apr 26
• 92 citations
  Aggressive breast cancer cells are dependent on activated Abl kinases for proliferation, anchorage-independent growth and survival.
  Divyamani Srinivasan, Jonathan T. Sims, Rina Plattner> ;Oncogene. 2008 Feb 14
• 24 citations
  Characterization of a sialic acid- and P-selectin glycoprotein ligand-1-independent adhesin activity in the granulocytotropic bacterium Anaplasma phagocytophilum.
  Dexter V. Reneer, Sarah A. Kearns, Tadayuki Yago, Jonathan T. Sims, Richard D. Cummings, Rodger P. McEver, Jason A. Carlyon> ;Cellular Microbiology. 2006 Dec 1
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