JonathanMSpergelMD

PubMed

• The Relationship Between Eosinophilic Esophagitis and Immunotherapy.
  Bridget E Wilson, Maria A Sacta, Benjamin L Wright, Jonathan Spergel, Nicole Wolfset> ;Immunology and Allergy Clinics of North America. 2024 May 1
• "Reducing Eosinophil Counts in Eosinophilic Esophagitis in Children Is Associated with Reduction in Later Stricture Development".
  Alexandra Strauss Starling, Yue Ren, Hongzhe Li, Jonathan M Spergel, Amanda B Muir, Kristle L Lynch, Chris A Liacouras, Gary W Falk> ;The American Journal of Gastroenterology. 2024 Apr 25
• Pediatric and adult EoE: A spectrum or distinct diseases?
  Stanislaw J Gabryszewski, Melanie A Ruffner, Jonathan M Spergel> ;The Journal of Allergy and Clinical Immunology. 2024 Mar 29
• Endoscopic and histologic utility of transnasal endoscopy in pediatric eosinophilic esophagitis.
  Eliana Shaul, Kanak V Kennedy, Zachary C Spergel, Shanaz Daneshdoost, Mark Mahon, Shivani Thanawala, Jonathan M Spergel, Benjamin Wilkins, Matthew J Ryan, Amanda B Muir> ;Journal of Pediatric Gastroenterology and Nutrition. 2024 May 1
• Who are the potential patients for omalizumab for food allergy?
  Hugh A Sampson, J Andrew Bird, David Fleischer, Wayne G Shreffler, Jonathan M Spergel> ;Annals of Allergy, Asthma & Immunology. 2024 May 1
• 3 citations
  Atopic dermatitis (eczema) guidelines: 2023 American Academy of Allergy, Asthma and Immunology/American College of Allergy, Asthma and Immunology Joint Task Force on P...
  Martin, S., Martin, S., Martin, S., Martin, S., Martin, S., Martin, S., , Derek K Chu, Lynda Schneider, Rachel Netahe Asiniwasis, Mark Boguniewicz, Anna De Benedetto, ...> ;Annals of Allergy, Asthma & Immunology. 2024 Mar 1
• 2 citations
  Omalizumab for the Treatment of Multiple Food Allergies.
  Robert A Wood, Alkis Togias, Scott H Sicherer, Wayne G Shreffler, Edwin H Kim, Stacie M Jones, Donald Y M Leung, Brian P Vickery, J Andrew Bird, Jonathan M Spergel, Ah...> ;The New England Journal of Medicine. 2024 Mar 7
• A case series of live attenuated vaccine administration in dupilumab-treated children with atopic dermatitis.
  Elaine C Siegfried, Lara Wine Lee, Jonathan M Spergel, Randy Prescilla, Sumeet Uppal, Anna Coleman, Ashish Bansal, Sonya L Cyr, Brad Shumel> ;Pediatric Dermatology. 2024 Feb 2
• Persistent esophageal changes after histologic remission in eosinophilic esophagitis.
  Melanie A Ruffner, Tetsuo Shoda, Megha Lal, Zoe Mrozek, Amanda B Muir, Jonathan M Spergel, Evan S Dellon, Marc E Rothenberg> ;The Journal of Allergy and Clinical Immunology. 2024 Apr 1
• Rise of gastrointestinal-based food allergy.
  Spergel, J.> ;Annals of Allergy, Asthma & Immunology. 2023 Dec 1
• 9 citations
  Systemic treatments for atopic dermatitis (eczema): Systematic review and network meta-analysis of randomized trials.
  Martin, S., Martin, S., Martin, S., Alexandro W L Chu, Melanie M Wong, Daniel G Rayner, Gordon H Guyatt, Juan Pablo Díaz Martinez, Renata Ceccacci, Irene X Zhao, Eric ...> ;The Journal of Allergy and Clinical Immunology. 2023 Dec 1
• 2 citations
  Topical treatments for atopic dermatitis (eczema): Systematic review and network meta-analysis of randomized trials.
  Martin, S., Martin, S., Martin, S., Derek K Chu, Alexandro W L Chu, Daniel G Rayner, Gordon H Guyatt, Juan José Yepes-Nuñez, Luis Gomez-Escobar, Lucia C Pérez-Herrera,...> ;The Journal of Allergy and Clinical Immunology. 2023 Dec 1
• Validation of the novel Eosinophilic Esophagitis Impact Questionnaire.
  Eilish McCann, Mirna Chehade, Jonathan M Spergel, Andrew Yaworsky, Tara Symonds, Jonathan Stokes, Sarette T Tilton, Xian Sun, Siddhesh Kamat> ;Journal of Patient-Reported Outcomes. 2023 Nov 27
• Anaphylaxis: A 2023 practice parameter update: Major changes in management of anaphylaxis.
  Sacta, M., Alsaati, N., Spergel, J.> ;Annals of Allergy, Asthma & Immunology. 2024 Feb 1
• For allergists, the solution is never violence!
  Jonathan Spergel, Larry Borish, Mitchell H Grayson, Matthew J Greenhawt, Donald Y M Leung, Francesca Levi-Schaffer, Jay A Lieberman, Melissa Moore-Clingenpeel, Anna No...> ;Annals of Allergy, Asthma & Immunology. 2024 Feb 1
• Breakthroughs in understanding and treating eosinophilic gastrointestinal diseases presented at the CEGIR/TIGERs Symposium at the 2022 American Academy of Allergy, Ast...
  Mirna Chehade, Benjamin L Wright, Dan Atkins, Seema S Aceves, Steven J Ackerman, Amal H Assa'ad, Maureen Bauer, Margaret H Collins, Scott P Commins, Carla M Davis, Eva...> ;The Journal of Allergy and Clinical Immunology. 2023 Dec 1
• 4 citations
  Recent Advances in the Treatment of Eosinophilic Esophagitis.
  Amiko M Uchida, Caitlin M Burk, Marc E Rothenberg, Glenn T Furuta, Jonathan M Spergel> ;The Journal of Allergy and Clinical Immunology. in Practice. 2023 Sep 1
• 1 citations
  Updated guidance regarding the risk of allergic reactions to COVID-19 vaccines and recommended evaluation and management: A GRADE assessment and international consensu...
  Matthew Greenhawt, Timothy E Dribin, Elissa M Abrams, Marcus Shaker, Derek K Chu, David B K Golden, Cem Akin, Akterini Anagnostou, Faisal ALMuhizi, Waleed Alqurashi, P...> ;The Journal of Allergy and Clinical Immunology. 2023 Aug 1
• 13 citations
  IgA deficiency destabilizes homeostasis toward intestinal microbes and increases systemic immune dysregulation.
  Peyton E Conrey, Lidiya Denu, Kaitlin C O'Boyle, Isaiah Rozich, Jamal Green, Jeffrey Maslanka, Jean-Bernard Lubin, Tereza Duranova, Brittany L Haltzman, Lauren Gianche...> ;Science Immunology. 2023 May 26
• 4 citations
  Phenotypic and Endotypic Determinants of Atopic Dermatitis Severity From the Atopic Dermatitis Research Network (ADRN) Registry.
  Eric L Simpson, Anna De Benedetto, Mark Boguniewicz, Peck Y Ong, Stephanie Lussier, Miguel Villarreal, Lynda C Schneider, Amy S Paller, Emma Guttman-Yassky, Jon M Hani...> ;The Journal of Allergy and Clinical Immunology. in Practice. 2023 Aug 1
• 2 citations
  Esophageal Epithelium and Lamina Propria Are Unevenly Involved in Eosinophilic Esophagitis.
  Girish Hiremath, Lili Sun, Margaret H Collins, Peter A Bonis, Nicoleta C Arva, Kelley E Capocelli, Mirna Chehade, Carla M Davis, Gary W Falk, Nirmala Gonsalves, Sandee...> ;Clinical Gastroenterology and Hepatology. 2023 Oct 1
• 2 citations
  Safety of Multifood Oral Immunotherapy in Children Aged 1 to 18 Years at an Academic Pediatric Clinic.
  Kim Nguyen, Megan O Lewis, Elizabeth Hanna, Maria Katerina C Alfaro, Kristen Corrigan, Jillian Buonanno, Rahul Datta, Terri Brown-Whitehorn, Jonathan M Spergel, Antone...> ;The Journal of Allergy and Clinical Immunology. in Practice. 2023 Jun 1
• 6 citations
  Values and Preferences of Patients and Caregivers Regarding Treatment of Atopic Dermatitis (Eczema): A Systematic Review.
  Martin, S., Martin, S., Keon Andre Maleki-Yazdi, Anja Fog Heen, Irene X Zhao, Gordon H Guyatt, Erica A Suzumura, Nima Makhdami, Lina Chen, Tonya Winders, Kathryn E Whe...> ;JAMA Dermatology. 2023 Mar 1
• 6 citations
  The role of biologics in pediatric food allergy and eosinophilic gastrointestinal disorders.
  Sayantani B Sindher, Suzanne Barshow, Jyothi Tirumalasetty, Stefania Arasi, Dan Atkins, Maureen Bauer, Philippe Bégin, Margaret H Collins, Antoine Deschildre, Alfred D...> ;The Journal of Allergy and Clinical Immunology. 2023 Mar 1
• 15 citations
  One-food versus six-food elimination diet therapy for the treatment of eosinophilic oesophagitis: a multicentre, randomised, open-label trial.
  Kara L Kliewer, Nirmala Gonsalves, Evan S Dellon, David A Katzka, Juan P Abonia, Seema S Aceves, Nicoleta C Arva, John A Besse, Peter A Bonis, Julie M Caldwell, Kelley...> ;The Lancet. Gastroenterology & Hepatology. 2023 May 1
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Journal Articles

• Original Article Food Protein-Induced Enterocolitis Syndrome Food Challenges: Experience from a Large Referral Center  
  Jennifer Heimall, Nicholas A Pawlowski, Jonathan M Spergel, Antonella Cianferoni, Joel Fiedler, Melanie A Ruffner, Rushani W Saltzman, Gita S Ram, ScienceDirect
• MOC: Difficult Cases Eosinophilic Esophagitis  
  Benjamin L Wright, Jonathan M Spergel, ScienceDirect
• A Review of Tertiary Referrals for Management of Pediatric Esophageal Eosinophilia  
  Amanda B Muir, Chris Liacouras, Jonathan M Spergel, Atu Agawu, Melanie A Ruffner, Ritu Verma, Joshua Eisenberg, Antonella Cianferoni, Frontiers in Neurology
• Clinical Communications Oral Viscous Budesonide Can Be Successfully Delivered Through a Variety of Vehicles to Treat Eosinophilic Esophagitis in Children  
  Chris Liacouras, Antonella Cianferoni, Ritu Verma, Jonathan M Spergel, ScienceDirect
• Author’s Response to Editorial on Atopy Patch Testing in Eosinophilic Esophagitis.  
  Yan, AC, Lauren, C, Honig, PJ and JM Spergel, Allergy Asthma Immunol 2006; 96 (2): 376-8
• Consultation and referral guidelines citing the evidence: How the allergist-immunologist can help.  
  Spergel JM, J Allergy Clin Immunol 2006: 117: S495-523
• Safety of TIM (Topical Calcineurin Immune Modulators).  
  Leung, DY and Spergel, and JM, Curr Allergy Asthma Rep. 2006 6(4):270-4
• Predictive values for food challenge-induced severe reactions: Development of a simple food challenge score.  
  Cianferoni A. Garrett J.P. Naimi D.R. Khullar K. Spergel J.M, Israel Medical Association Journal. 14 (1) (pp 24-28)
• Atopic Dermatitis: An evidence-based management approach.  
  Pien, G and Spergel, JM, JCOM: 14 (8): 465-474
• The use of pimecrolimus cream in Atopic Dermatitis.  
  Spergel, JM, Clin. Cosmetic Dermatology (2009) 2:85-93
• Atopic Dermatitis (review).  
  Spergel, JM, LC Schnieder, Internet J. of Allergy and Immunol. 1997; 1(1) 1-8
• Natural history of peanut allergy.  
  Spergel, JM and JM Fiedler, Curr Opin in Pediatr. 2001; (6): 517-22
• Eosinophilic esophagitis in adults and children: evidence for a food allergy component in many patients.  
  Spergel, J.M, Current Opin in Allergy Clin Immunol, 2007 Jun;7(3):274-278
• Eosinophilic esophagitis in children and adults: a systematic review and consensus recommendations for diagnosis and treatment.  
  Furuta, GT, Liacouras, CA, Collins, MH, Gupta, SK, Justinich, C, Putnam, PE, Bonis, P, Hassall, E, Straumann, A, Rothenberg, ME, and First Interna..., Gastroenterology. 2007 Oct;133(4):1342-63. Epub
• Food Allergy Practice Parameters.  
  Chapman, JA, Bernstien, IL, Lee, FE, Oppenheimer, and J, Ann Allergy Asthma Immunol 96: S1-S68
• Ask the Doc: The use of patch testing in Eosinophilic Esophagitis.  
  Spergel and JM, Amer. Partnership for Eos. Disorders
• What foods are most likely to cause Eosinophilic Esophagitis? and What is the role of allergy testing for EE.  
  Spergel, JM, Amer. Partnership for Eos. Disorders
• Atopic Dermatitis and Allergies.  
  Spergel, JM, The Advocate, National Eczema Association for Science and Education Quarterly Newspaper
• Eczema Exposed.  
  Spergel, JM, American Acad. Allergy Immunology Web Site. Consumer and Patient Education
• Allergy Evaluation in Eosinophilic Esophagitis.  
  Spergel, JM, Humana
• Foods/Food Additives.  
  Spergel and JM and JF Fiedler, Immunol Allergy Clin North Am. 2005; 25(1): 149-67
• Eosinophilic Gastrointestinal Diseases, Manual in Allergy and Immunology 5E.  
  Brown-Whitehorn, TA, Verma, R, Spergel, and JM Eosinophilic, Lippincott
• Development of a simple food challenge score.  
  Cianferoni A. Garrett J.P. Naimi D.R. Khullar K. Spergel J.M, Israel Medical Association Journal. 14 (1) (pp 24-28), 2012
• Effect of cat and daycare exposures on the risk of asthma in children with atopic dermatitis.  
  Gaffin JM, Spergel JM, Boguniewicz M, Eichenfield LF, Paller AS, Fowler JF Jr, Dinulos JG, Tilles SA, Schneider LC, and Phipatanakul W, Allergy Asthma Proc. 2012 May;33(3):282-8
• Atopic Dermatitis and Atopic March.  
  Spergel, JM and AS Paller, J. Allergy Clin. Immunol. 2003; 112(6 Suppl): S118-27
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Books/Book Chapters

• Atopic Dermatitis. 
  Chapter: PA2007 
  Page 981 - 990Yan, AC, Lauren, C, Honig, and PJ and JM SpergelEditors: LA Zaoutis, VW Chaing.ElsevierEdition 155,
• Asthma. 
  Chapter: Chapter 75 
  Page 463 - 481Heltzer and M and JM SpergelEditors: LA Zaoutis, VW Chaing.Elsevier
• Fogg, Pediatric Asthma. 
  Spergel and JM and MIEditors: RE Rakel and ET Bope.Conn’s Current Therapy
• Food Allergy. 
  Chapter: Gastrointestinal Disease 
  Spergel and JM and NA PawlowskiEditors: Mascarenhas, M, Piccoli, D.
• Immunology and Allergy Clinics of North America. 
  Chapter: Genetics of Allergic and Immunoregulatory Disorders 
  Sullivan and KE and Spergel JM
• Role of Allergy in Atopic Dermatitis. 
  Spergel and JMEditors: Basow, DS.
• Treatment of Severe Atopic Dermatitis. 
  Spergel, JMEditors: Basow, DS.
• Allergen-Induced Model of Murine Atopic Dermatitis. 
  Page 423 - 432Spergel, JMAnimal Models of Human Inflammatory Diseases, CRC Edition Chap,
• Atopic Dermatitis in Childhood and Adolescence. 
  Chapter: Pediatr Adolesc Med 
  Kiess W, Werfel T, Spergel JMEditors: Basel, Karger.
• Allergies and Asthma; Asthma Day to Day and Asthma Medication. 
  Spergel and JMGuide to Asthma, The Children Hospital of PhiladelphiaEdition Chap,
• Allergy Testing in Eosinophilic Esophagitis, Eosinophilic Esophagitis. 
  Chapter: Elsevier 
  Cianferoni, AC and Spergel, and JMEditors: Liacouras, Markowitz.
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Abstracts/Posters

• Liacouras Increasing Incidence or Increasing Detection of Esophageal Eosinophilia: A Re-evaluation of Esophageal Biopsies from 1985 to 2005.
  Franciosi, JP, J. Osman, C. Li, J. Shults, M. Leonard, J. Spergel, E. Ruchelli, and C.A, Allergy Clin. Immunol. 2008; 121 (2) S71
• Milk-Derived Glycoshingolipids (GSL) Specifically Ligate The Invariant NKT Cell (iNKT) T Cell Receptor (TCR), Induce iNKT Proliferation And Promote Th2 Cytokine Expres...
  Spergel and JM, J. Allergy Clin. Immunol 2009; 123 (3), 724
• Reslizumab in Children and Adolescents with Eosinophilic Esophagitis: Results of a Double-Blind, Randomized, Placebo-Controlled Study.
  Spergel JM, Rothenberg ME, Collins MH, Furuta GT, Markowitz JE, Fuchs G, O’Gorman MA, Abonia JP, Young J, Henkel T, Wilkins HJ, and Liacouras CA, Digestive Disease Week, Plenary
• Reslizumab in Children and Adolescents with Eosinophilic Esophagitis: Results of a Double-Blind, Randomized, Placebo-Controlled Study.
  Spergel JM, Rothenberg ME, Collins MH, Furuta GT, Markowitz JE, Fuchs G, O’Gorman MA, Abonia JP, Young J, Henkel T, Wilkins HJ, and Liacouras CA, International Eosinophilic Society Meeting
• Pediatric Asthma: A review.
  Spergel, JM and R Clayton, Biomedicina, 5 (3): 117-124
• The Utility of Combining Skin Prick and Specific IgE Antibody Testing as a Predictor of Clinical Reactivity to Milk, Egg, and Peanut.
  Naimi, DR N.M. Paranich, J.M. Spergel, J.L. Beausoleil, Amer. Assoc. Allergy Asthma and Immunol. Annual Meeting, Miami, FL, 2007. J. Allergy Clin. Immunol.
• Allergy Asthma and Immunol. Annual Meeting.
  Franciosi, JP, J. Osman, C. Li, J. Shults, M. Leonard, J. Spergel, E. Ruchelli, and C.A, J. Allergy Clin. Immunol. 2008; 121 (2) S71., Philadelphia, PA
• Diagnosis and Treatment of Eosinophilic Esophagitis.
  Spergel, JM, Brown-Whitehorn, TA, Clin Outcomes Manage 2009 May;16(5):237-243
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Lectures

• 2012 Annual Scientific Meeting of American College of Allergy, Asthma & Immunology (ACAAI) 
  American College of Allergy, Asthma & Immunology, Anaheim, California - 11/8/2012
• Atopic March and Eosinophilic Esophagitis. 
  Creighton Medical Center, Omaha, Nebraska
• Eosinophilic Esophagitis, New Jersey Allergy Society. 
• Patch Testing in Eosinophilic Esophagitis, American Academy of Allergy Asthma and Immunology. 
  International Gastrointestinal Esophageal Research Symposium, Philadelphia, PA
• “Natural History of Atopic Dermatitis” and “Non-IgE Mediated Food Allergies”. 
  Immunology Annual Meeting, Miami Beach, FL
• Eosinophilic Esophagitis and Food Allergy. 
  South Carolina Allergy Society, Charleston, SC
• Eosinophilic Esophagitis: Diagnostic Testing. 
  Illinois Allergy Society Meeting, Chicago, IL
• Peanut Allergy: Myths and Reality. 
  Division of Allergy and Immunology Annual CME Course, Philadelphia, PA
• Chronic Urticaria: Anti-histamines and Beyond. 
  American College of Asthma Allergy and Immunology 2006 Annual Meeting, Philadelphia, PA
• Food Allergy in Atopic Dermatitis: Differentiating Myth from Reality, CHOP Dermatology Course. 
• Food Allergies in Eosinophilic Esophagitis. 
  Texas Allergy and Asthma Society Meeting, San Antonio, TX
• Eosinophilic Gastrointestinal Disease. 
  Barcelona, Spain
• Patch Testing in Atopic Dermattiis and Eosinophilic Esophagitis. 
  Pennsylvania Allergy Society Meeting, Hershey, PA
• Genetics of Eosinophilic Diseases. 
  Eos Connection 2008, San Diego, CA
• Dietary Interventions: How to Test and What to Do. 
  Eosinophilic Esophagitis. San Diego, CA
• Eosinophilic Esophagitis, Treatment and Management. 
  Orange County, CA
• Patch Testing in Eosinophilic Esophagitis, Gastrointestinal Disease: When is it allergy, The use of elimination diets in Eosinophilic Esophagitis. 
  American Academy of Allergy Asthma and Immunology 62nd Annual Meeting, Washington, DC
• Eosinophilic Esophagitis and Atopic Dermatitis, 46th Annual Georgia Allergy Immunology Meeting. 
• Eosinophilic Esophagitis-Plenary talk-Pediatric Section. 
  Warsaw, Poland
• Food Allergy in Atopic Dermatitis. 
  Philadelphia, PA
• The Role of Food Allergy and Aeroallergens in Eosinophilic Esophagitis. 
  Grand Rounds, Medical College of Georgia
• Treatment and Diagnosis of Eosinophilic Esophagitis. 
  University of South Florida Medical School, Tampa, FL
• The Role of Genetics in Eosinophilic Esophagitis (Symposium Talk); Treatment and Evaluation in Eosinophilic Esophagitis; Food Allergy Testing (Plenary Talk for Allied ... 
  American Academy of Allergy Asthma and Immunology 63rd Annual Meeting, New Orleans, LA
• The role of food allergy in Eosinophilic Esophagitis, Treatment and Management of Atopic Dermatitis. 
  Toronto
• Approach and treatment for Eosinophilic Esophagitis. 
  Istanbul, Turkey
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Other

• Report of the Topical Calcineurin Inhibitor Task Force of the ACAAI and AAAAI. 
  Fonacier, L, JM Spergel, EN Charlesworth, E Wheldon, V Beltani, J Bernhisel-Broadbent, M Boguniewicz, and and DY Leung
  http://www.aaaai.org/members/only/position_statements/calcineurin_task_force.pdf
• Non-prescription Treatment in Atopic Dermatitis. 
  Spergel, J.M
• Atopic Dermatitis, Risks of Topical Steroids and Calicineurin Inhibitors. 
  Spergel, JM, Hanifin, J, Heibert, A, Boguniewicz, and M
• Peanut Allergy. 
  Spergel and JM
  Fox-News, Philadelphia, PA
• Methods of Diagnosis: Skin Prick Test vs. Patch Testing. 
  Spergel, JM
• Allergy testing in eosinophilic esophagitis 
  Spergel JM
  http://www.uptodate.com/contents/allergy-testing-in-eosinophilic-esophagitis
  UpToDate, Wolters Kluwer Health - 2012-12-18
• Management of severe refractory atopic dermatitis (eczema) 
  Spergel JM
  http://www.uptodate.com/contents/management-of-severe-refractory-atopic-dermatitis-eczema
  UpToDate, Wolters Kluwer Health - 2012-02-21
• Role of allergy in atopic dermatitis (eczema) 
  Spergel JM
  http://www.uptodate.com/contents/role-of-allergy-in-atopic-dermatitis-eczema
  UpToDate, Wolters Kluwer Health - 2012-08-14
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