Jonathan Zager MD
Melanoma, Surgical Oncology (Other than Breast)
Chief Academic Officer Designated Institutional Official Director of Regional Therapies Senior Member, Department of Cutaneous Oncology, Moffitt Cancer Center Professor of Surgery and Chair of the Department of Oncologic Sciences, USF-Morsani College of Medicine.
10920 North McKinley DriveTampa, FL 33612
Overview of Dr. Zager
Dr. Jonathan Zager is a surgical oncologist, Director of Regional Therapies and Senior Member in the Cutaneous Oncology Department at the H. Lee Moffitt Cancer Center and Research Institute in Tampa FL. He is the Chief Academic Officer at Moffitt Cancer Center as well as the Designated Institutional Official (ACGME). He is a professor of surgery and Chair of the Department of Oncologic Sciences at the University of South Florida Morsani College of Medicine. He received his medical degree from Tel Aviv University Sackler and has been in practice 20 years. He specializes in melanoma and surgical oncology (other than breast) and is experienced in the multidisciplinary management of melanoma, Merkel cell carcinoma and other complicated soft tissue and cutaneous malignancies. Dr. Zager has published nearly 300 peer reviewed articles edited textbooks and textbook chapters. He has given over 350 talks national and internationally on melanoma, Merkel cell carcinoma, basal and squamous cell carcinomas including topics such as regional therapies and the management of complex advanced and recurrent disease.
Education & Training
University of Texas M D Anderson Cancer CenterFellowship, Complex General Surgical Oncology, 2004 - 2006
Montefiore Medical Center/Albert Einstein College of MedicineResidency, Surgery, 2001 - 2004
Memorial Sloan Kettering Cancer CenterFellowship, Hepatobiliary Surgery, 1999 - 2001
Zucker School of Medicine at Hofstra/NorthwellResidency, Surgery, 1997 - 1999
Tel Aviv University SacklerClass of 1997
Certifications & Licensure
FL State Medical License 2006 - 2027
GA State Medical License 2014 - 2026
TX State Medical License 2004 - 2026
NY State Medical License 1998 - 2005
American Board of Surgery Surgery
Awards, Honors, & Recognition
- CMS Meaningful Use Stage 1 Certification FairWarning® Patient Privacy Monitoring, FairWarning Technologies, LLC, 2016-2017
- CMS Meaningful Use Stage 1 Certification PowerChart (CQM), Cerner Corporation, 2016-2017
- CMS Meaningful Use Stage 1 Certification HealtheLife and PowerChart, Cerner Corporation, 2016-2017
Clinical Trials
- Study of RAD001 in Soft Tissue Extremity and/or Retroperitoneal Sarcomas Start of enrollment: 2010 Jan 01
- Vaccine Combining Multiple Class I Peptides and Montanide ISA 51VG With Escalating Doses of Anti-PD-1 Antibody Nivolumab or Ipilimumab With Nivolumab For Patients With Resected Stages IIIC/ IV Melanoma Start of enrollment: 2010 Aug 13
- Study of XL888 With Vemurafenib for Patients With Unresectable BRAF Mutated Stage III/IV Melanoma Start of enrollment: 2012 Jul 27
Publications & Presentations
PubMed
- International Survey on Evidence for Index Lymph Node Surgery After Neoadjuvant Systemic Therapy for Stage III Melanoma.Elan Novis, Mervi Rautalin, Rodabe N Amaria, Paolo A Ascierto, Christian U Blank
Annals of Surgical Oncology. 2026-03-01 - ASO Visual Abstract: Recurrence and Survival Outcomes in Patients with Primary Merkel Cell Carcinoma with Positive, Negative or Not Performed Sentinel Lymph Node Biopsy.Michelle M Dugan, Caitlyn Balsay-Patel, Nicholas Chin, Jacob Israeli, Kimberly R Ward
Annals of Surgical Oncology. 2026-03-01 - ASO Visual Abstract: Prognostic Value of Non-Nodal Regional Metastases in Predicting Sentinel Lymph Node Status in Cutaneous Melanoma: Multicenter Analysis of the Sent...Nazia Riaz, Stanley P Leong, Mohammed Kashani-Sabet, Richard L White Jr, John T Vetto
Annals of Surgical Oncology. 2026-02-26
Journal Articles
- Microsatellitosis in Patients with MelanomaRichard L White, Mark B Faries, Stanley P Leong, Andrew J Sinnamon, Jane L Messina, Barbara A Pockaj, Giorgos C Karakousis, Edmund K Bartlett, John T Vetto, Vernon K S..., Annals of Surgical Oncology
- Management of Sentinel Lymph Node Metastasis in Merkel Cell Carcinoma: Completion Lymphadenectomy, Radiation, or Both?C Wayne Cruse, Vernon K Sondak, Ricardo J Gonzalez, Daniel E Oliver, Jane L Messina, Louis B Harrison, Jonathan S Zager, Amod A Sarnaik, Annals of Surgical Oncology
- Talimogene Laherparepvec (TVEC) for the Treatment of Advanced Melanoma: A Single-Institution ExperienceJonathan S Zager, Amod A Sarnaik, Annals of Surgical Oncology
Press Mentions
Gene Expression Test Helps Identify Risk of Melanoma Spreading to Lymph NodesOctober 24th, 2025- Moffitt Study Shows Gene Expression Test Can Help Identify Melanoma Patients at Low Risk of Lymph Node SpreadOctober 23rd, 2025
- Moffitt Study Reveals Gene Expression Test Accurately Identifies Melanoma Patients with Low Risk of Lymph Node MetastasisOctober 22nd, 2025
Committees
- Chair, Disease Site Working Group - Melanoma/ Sarcoma. SSO
Professional Memberships
- Member
- Member
Insurance Accepted
- Aetna Choice POS II
Aetna HMO
AvMed Health Open Access
BCBS Blue Card PPO
BCBS California CaliforniaCare HMO
BCBS California PPO
BCBS Florida BlueCare HMO
BCBS Florida NetworkBlue
BCBS Florida Preferred Patient Care PPO
Blue Shield California PPO
CIGNA HMOCIGNA Open Access
CIGNA PPO
Coventry Florida - Employer Group PPO
First Health PPO
Great West PPO
Humana ChoiceCare Network PPO
MagnaCare PPO
Multiplan PPO
Pacificare HMO
United Healthcare - Direct Choice Plus POS
United Healthcare - Direct Options PPO - Please verify your coverage with the provider's office directly when scheduling an appointment
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