JongRhoMD

PubMed

• Human retinal ganglion cell neurons generated by synchronous BMP inhibition and transcription factor mediated reprogramming.
  Devansh Agarwal, Nicholas Dash, Kevin W Mazo, Manan Chopra, Maria P Avila, Amit Patel, Ryan M Wong, Cairang Jia, Hope Do, Jie Cheng, Colette Chiang, Shawna L Jurlina, ...> ;NPJ Regenerative Medicine. 2023 Sep 29
• 3 citations
  Postictal hypoxia involves reactive oxygen species and is ameliorated by chronic mitochondrial uncoupling.
  Bianca R Villa, Antis G George, Timothy E Shutt, Patrick G Sullivan, Jong M Rho, G Campbell Teskey> ;Neuropharmacology. 2023 Nov 1
• 3 citations
  Intermittent vs continuous ketogenic diet: Impact on seizures, gut microbiota, and mitochondrial metabolism.
  Jane Shearer, Morris H Scantlebury, Jong M Rho, Thomas A Tompkins, Chunlong Mu> ;Epilepsia. 2023 Aug 1
• Proposed anti-seizure medication combinations with rufinamide in the treatment of Lennox-Gastaut syndrome: Narrative review and expert opinion.
  Raman Sankar, Michael Chez, J Eric Pina-Garza, Tracy Dixon-Salazar, J Robert Flamini, Ann Hyslop, Patricia McGoldrick, John J Millichap, Trevor Resnick, Jong M Rho, St...> ;Seizure. 2023 Aug 1
• 4 citations
  Sudden unexpected death in epilepsy is prevented by blocking postictal hypoxia.
  Antis G George, Jordan S Farrell, Roberto Colangeli, Alexandra K Wall, Renaud C Gom, Mitchell T Kesler, Cristiane Rodriguez de la Hoz, Bianca R Villa, Tefani Perera, J...> ;Neuropharmacology. 2023 Jun 15
• 6 citations
  Gut-based manipulations spur hippocampal mitochondrial bioenergetics in a model of pediatric epilepsy.
  Chunlong Mu, Thomas A Tompkins, Jong M Rho, Morris H Scantlebury, Jane Shearer> ;Biochimica Et Biophysica Acta. Molecular Basis of Disease. 2022 Sep 1
• 8 citations
  Targeted gut microbiota manipulation attenuates seizures in a model of infantile spasms syndrome.
  Chunlong Mu, Naghmeh Nikpoor, Thomas A Tompkins, Anamika Choudhary, Melinda Wang, Wendie N Marks, Jong M Rho, Morris H Scantlebury, Jane Shearer> ;JCI Insight. 2022 Jun 22
• 10 citations
  Selective Probiotic Treatment Positively Modulates the Microbiota-Gut-Brain Axis in the BTBR Mouse Model of Autism.
  Angela Pochakom, Chunlong Mu, Jong M Rho, Thomas A Tompkins, Shyamchand Mayengbam, Jane Shearer> ;Brain Sciences. 2022 Jun 14
• 54 citations
  The metabolic basis of epilepsy.
  Jong M Rho, Detlev Boison> ;Nature Reviews. Neurology. 2022 Jun 1
• 1 citations
  Addition of Prebiotics to the Ketogenic Diet Improves Metabolic Profile but Does Not Affect Seizures in a Rodent Model of Infantile Spasms Syndrome.
  Chunlong Mu, Angela Pochakom, Raylene A Reimer, Anamika Choudhary, Melinda Wang, Jong M Rho, Morris H Scantlebury, Jane Shearer> ;Nutrients. 2022 May 26
• 8 citations
  Abnormal oxidative metabolism in the cuprizone mouse model of demyelination: An in vivo NIRS-MRI study.
  Mada Hashem, Qandeel Shafqat, Ying Wu, Jong M Rho, Jeff F Dunn> ;Neuroimage. 2022 Apr 15
• 13 citations
  Probiotics counteract hepatic steatosis caused by ketogenic diet and upregulate AMPK signaling in a model of infantile epilepsy.
  Chunlong Mu, Naghmeh Nikpoor, Thomas A Tompkins, Jong M Rho, Morris H Scantlebury, Jane Shearer> ;Ebiomedicine. 2022 Feb 1
• 22 citations
  Seizure modulation by the gut microbiota and tryptophan-kynurenine metabolism in an animal model of infantile spasms.
  Chunlong Mu, Anamika Choudhary, Shyamchand Mayengbam, Karlene T Barrett, Jong M Rho, Jane Shearer, Morris H Scantlebury> ;Ebiomedicine. 2022 Feb 1
• 26 citations
  Pharmacokinetics and central accumulation of delta-9-tetrahydrocannabinol (THC) and its bioactive metabolites are influenced by route of administration and sex in rats.
  Samantha L Baglot, Catherine Hume, Gavin N Petrie, Robert J Aukema, Savannah H M Lightfoot, Laine M Grace, Ruokun Zhou, Linda Parker, Jong M Rho, Stephanie L Borgland,...> ;Scientific Reports. 2021 Dec 14
• 4 citations
  Three dimensional microelectrodes enable high signal and spatial resolution for neural seizure recordings in brain slices and freely behaving animals.
  Pierre Wijdenes, K. Haider, Cezar Gavrilovici, B. Gunning, Marshal D. Wolff, T. Lijnse, Ryden Armstrong, G. C. Teskey, Jong M. Rho, Colin Dalton, Naweed I. Syed> ;Scientific Reports. 2021 Nov 9
• 12 citations
  The link between brain acidosis, breathing and seizures: a novel mechanism of action for the ketogenic diet in a model of infantile spasms
  Anamika Choudhary, Chunlong Mu, Karlene T. Barrett, Behshad Charkhand, Christine Williams-Dyjur, Wendie N. Marks, Jane Shearer, Jong M. Rho, Morris H. Scantlebury> ;Brain Communications. 2021 Oct 1
• 4 citations
  Gene-Targeted Therapies in Pediatric Neurology: Challenges and Opportunities in Diagnosis and Delivery.
  Renée A. Shellhaas, Gabrielle deVeber, Joshua L. Bonkowsky, Erika F. Augustine, Alexander G. Bassuk, Daniel G. Calame, Melisa Carrasco, Nomazulu Dlamini, Ryan J. Felli...> ;Pediatric Neurology. 2021 Sep 25
• 8 citations
  A ketogenic diet affects brain volume and metabolome in juvenile mice.
  Shyamchand Mayengbam, Jacob Ellegood, Mitch Kesler, Raylene A. Reimer, Jane Shearer, Kartikeya Murari, Jong M. Rho, Jason P. Lerch, Ning Cheng> ;Neuroimage. 2021 Sep 13
• 14 citations
  Prebiotic, Probiotic, and Synbiotic Consumption Alter Behavioral Variables and Intestinal Permeability and Microbiota in BTBR Mice.
  Jodi E. Nettleton, Teja Klancic, Alana Schick, Ashley C. Choo, Ning Cheng, Jane Shearer, Stephanie L. Borgland, Jong M. Rho, Raylene A. Reimer> ;Microorganisms. 2021 Aug 29
• 44 citations
  Genotype-phenotype correlations in SCN8A-related disorders reveal prognostic and therapeutic implications.
  Katrine M Johannesen, Yuanyuan Liu, Mahmoud Koko, Cathrine E Gjerulfsen, Lukas Sonnenberg, Julian Schubert, Christina Fenger, Ahmed Eltokhi, Maert Rannap, Nils A Koch,...> ;Brain. 2021 Aug 25
• 5 citations
  Metabolism-based therapies for epilepsy: new directions for future cures.
  Mackenzie C. Cervenka, Juan M. Pascual, Jong M. Rho, Elizabeth A. Thiele, Gary Yellen, Vicky Whittemore, Adam L. Hartman> ;Annals of Clinical and Translational Neurology. 2021 Jul 11
• 4 citations
  Ketogenic diet-mediated seizure reduction preserves CA1 cell numbers in epileptic Kcna1-null mice: An unbiased stereological assessment.
  Kristina A. Simeone, Julianne Wilke, Stephanie A. Matthews, Timothy A. Simeone, Jong M. Rho> ;Epilepsia. 2021 Jul 7
• 5 citations
  The ketogenic diet raises brain oxygen levels, attenuates postictal hypoxia, and protects against learning impairments
  Renaud C. Gom, Dhyey Bhatt, Bianca R. Villa, Antis G. George, Alexander W. Lohman, Richelle Mychasiuk, Jong M. Rho, G. Campbell Teskey> ;Neurobiology of Disease. 2021 Jul 1
• 1 citations
  Creation and implementation of an electronic health record note for quality improvement in pediatric epilepsy: Practical considerations and lessons learned
  Jeffrey Buchhalter, Morris H. Scantlebury, Sabrina D'Alfonso, Juan Pablo Appendino, Luis Bello Espinosa, Brian L. Brooks, Curtis S Claassen, Jane Corbeil, David Czank,...> ;Epilepsia Open. 2021 Mar 10
• 18 citations
  Metabolic epilepsies amenable to ketogenic therapies: Indications, contraindications, and underlying mechanisms.
  Cezar Gavrilovici, Jong M. Rho> ;Journal of Inherited Metabolic Disease. 2021 Jan 1
• Join now to see all

Journal Articles

• Abnormal Capillary Vasodynamics Contribute to Ictal Neurodegeneration in Epilepsy  
  Jong M Rho, David M Treiman, Nature

Other

• Diet and the Brain: Is There a Bona Fide Scientific Connection? 
  Jong Rho, 4th Annual Metabolic Health Summit
  Long Beach, California - 1/30/2020
• “Ketogenic Diet and the Gut Microbiome,” and “The Mode(s) of Action of the Ketogenic Diet” 
  Jong Rho, Dutch Neurological Society Meeting, and Ketogenic Diet Interest Group
  Rotterdam, Netherlands - 9/4/2019
• UPDATE LECTURE: Working Mechanisms of Ketogenic Diets 
  Jong Rho, Society for the Study of Inborn Errors of Metabolism, Annual International Congress
  Rotterdam, Netherlands - 9/2/2019
• Ketogenic Diets and Neurogastronomic Implications 
  Jong Rho, 4th Annual International Society of Neurogastronomy Conference
  New Orleans, Louisiana - 6/20/2019
• Epilepsy Across the Lifespan 
  Jong Rho, 2nd Annual Banff International Epilepsy Symposium
  Banff, Alberta, Canada - 2/15/2019
• Ketogenic Diet for Autism Spectrum Disorder: Evidence for Mitigating Core Symptoms 
  Jong Rho, 3rd Annual Metabolic Health Summit
  Long Beach, California - 1/31/2019
• Targeting Mitochondria for Seizure Control 
  Jong Rho, University of California at Irvine, EpiCenter Seminar Series
  1/7/2019
• Ketogenic and Metabolism-Based Therapies for Epilepsy: Summary of Progress and Future Directions 
  Jong Rho, American Epilepsy Society Annual Meeting, Pediatric State-of-the-Art Symposium
  New Orleans, Louisiana - 12/1/2018
• Gut Microbiome and Neurological Disorders 
  Jong Rho, UNLIKE Minds Summit
  British Columbia - 11/21/2018
• Neurometabolic Treatments for Epilepsy: Scientific Basis and Clinical Evidence 
  JM Rho, 52nd Congress of the Japan Epilepsy Society
  Yokohama, Japan - 10/24/2018
• “Overview of Mechanisms of the Ketogenic Diet” (Pre-Congress Workshop, Practical Implementation of Ketogenic Therapy), “History of Ketogenic Diet Symposia”, “Basic Mec... 
  JM Rho, 6th Global Symposium on Ketogenic Therapies for Neurological Disorders
  Jeju, South Korea - 10/5/2018
• Mechanism of Action of the Ketogenic Diet: Is This Still a Mystery 
  Rho JM, 41st Anniversary Meeting of the Canadian League Against Epilepsy
  St. John’s, Newfoundland, Canada - 9/21/2018
• Join now to see all