JordanElizabethLakeMD

Infectious Disease • Houston, TX

Associate Professor, Medicine, University of Texas Health Science Center at Houston

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Office
2015 Thomas St
Houston, TX 77009
Phone+1 713-873-4040

Fax+1 832-487-2011
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Education & Training

UCLA David Geffen School of Medicine/UCLA Medical CenterFellowship, Infectious Disease, 2007 - 2011
Baylor College of MedicineResidency, Internal Medicine, 2004 - 2007
Baylor College of MedicineClass of 2004

Certifications & Licensure

CA State Medical License 2007 - Present
TX State Medical License 2018 - 2025
American Board of Internal Medicine Infectious Disease

Clinical Trials

HIV and Fat Accumulation Start of enrollment: 2010 May 01
Completed
Phase 2
Vitamin D in HIV-Infected Patients on HAART Start of enrollment: 2010 Oct 01
Completed
Not Applicable
A Clinical Trial for People HIV+ Age > 50 at Risk for Heart Disease Start of enrollment: 2012 Aug 01
Completed
Phase 2
Long-term Observational Study in HIV Subjects Exposed to EGRIFTA® Start of enrollment: 2013 Feb 01
Terminated
Effects of Vitamin D Insufficiency in Man Start of enrollment: 2010 Aug 01
Completed
Not Applicable
Telmisartan to Reduce AIDS-Related Fibrotic and Inflammatory Contributors (TRAFIC Study) Start of enrollment: 2014 Jan 01
Completed
Phase 2
A Pilot Study to Examine Efficacy of Peer Mentoring in Promoting Medication Adherence Among People Living With HIV/AIDS Start of enrollment: 2013 Sep 01
Unknown status
Not Applicable
(mo)BETTA Trial in Transwomen for Optimization of ART Start of enrollment: 2018 Jun 06
Terminated
Phase 4
Study of Semaglutide for Non-Alcoholic Fatty Liver Disease (NAFLD), a Metabolic Syndrome With Insulin Resistance, Increased Hepatic Lipids, and Increased Cardiovascular Disease Risk (The SLIM LIVER Study) Start of enrollment: 2020 Oct 01
Completed
Phase 2
Efprezimod Alfa (CD24Fc, MK-7110) as a Non-antiviral Immunomodulator in COVID-19 Treatment (MK-7110-007) Start of enrollment: 2020 Apr 24
Completed
Phase 3
Study to Evaluate the Efficacy and Safety of Leronlimab for Patients With Severe or Critical Coronavirus Disease 2019 (COVID-19) Start of enrollment: 2020 Apr 15
Active, not recruiting
Phase 2
Ramipril for the Treatment of COVID-19 Start of enrollment: 2020 May 11
Completed
Phase 2
Explorations Into the Mechanism for INSTI-associated Weight Gain: a Focus on Energy Balance Start of enrollment: 2020 Oct 22
Completed
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Publications & Presentations

PubMed

Cannabis Use and Biomarkers of Inflammation, Immune Activation, and Microbial Translocation in Persons with HIV.
Okafor, C., Somasunderam, A., Gelfond, J., Javanbakht, M., Gorbach, P., Shoptaw, S., Schmitz, J., Lake, J.> ;Cannabis and Cannabinoid Research. 2024 Feb 9
2 citations
Prevalence of steatotic liver disease, MASLD, MetALD and significant fibrosis in people with HIV in the United States.
Vilar-Gomez, E., Wilson, L., Gawrieh, S., Woreta, T., Lake, J., Price, J., Naggie, S., Sterling, R., Heath, S., Corey, K., Cachay, E., Ajmera, V., Tonascia, J., Sulkow...> ;Alimentary Pharmacology & Therapeutics. 2024 Mar 1
Pharmacogenetics of weight gain following switch from efavirenz- to integrase inhibitor-containing regimens.
Kunling Wu, John Koethe, Todd Hulgan, Todd Brown, Sara H Bares, Katherine Tassiopoulos, Jordan E Lake, Michael Leonard, David C Samuels, Kristine Erlandson, David W Haas> ;Pharmacogenetics and Genomics. 2024 Feb 1
Proprotein convertase subtisilin/kexin 9 levels decline with hepatitis C virus therapy in people with HIV/hepatitis C virus and correlate with inflammation.
Malini M Gandhi, Kim-Lien Nguyen, Jordan E Lake, Diana Liao, Aleen Khodabakhshian, Mario Guerrero, Chrisandra L Shufelt, Wilbert C Jordan, Eric S Daar, Debika Bhattach...> ;AIDS. 2024 Mar 1
Social Networks Play a Complex Role in HIV Prevention Knowledge, Attitudes, Practices, and the Uptake of PrEP Through Transgender Women Communities Centered Around Thr...
Tijana Temelkovska, Kathleen Moriarty, Leyla Huerta, Amaya Perez-Brumer, Eddy Segura, Ryan Colby Passaro, Jordan E Lake, Jesse Clark, Cherie Blair> ;Journal of the International Association of Providers of AIDS Care. 2023 Sep 27
3 citations
Ramipril for the Treatment of COVID-19: RAMIC, a Randomized, Double-Blind, Placebo-Controlled Clinical Trial.
Daniel Q Huang, Veeral Ajmera, Christian Tomaszewski, Andrew LaFree, Ricki Bettencourt, Wesley K Thompson, Davey M Smith, Atul Malhotra, Ravindra L Mehta, Vaishal Toli...> ;Advances in Therapy. 2023 Nov 1
Adipose Tissue Dysfunction and Energy Balance Paradigms in People Living With HIV.
Claudia E Ramirez Bustamante, Neeti Agarwal, Aaron R Cox, Sean M Hartig, Jordan E Lake, Ashok Balasubramanyam> ;Endocrine Reviews. 2024 Mar 4
Obesity Modifies the Relationship Between Raltegravir and Dolutegravir Hair Concentrations and Body Weight Gain in Women Living with HIV.
Cecile D Lahiri, C Christina Mehta, Craig Sykes, Sheri D Weiser, Frank Palella, Jordan E Lake, John W Mellors, Deborah Gustafson, Audrey L French, Adaora A Adimora, De...> ;AIDS Research and Human Retroviruses. 2023 Dec 1
2 citations
Burden of fatty liver and hepatic fibrosis in persons with HIV: A diverse cross-sectional US multicenter study.
Samer Gawrieh, Jordan E Lake, Paula Debroy, Julia A Sjoquist, Montreca Robison, Mark Tann, Fatih Akisik, Surya S Bhamidipalli, Chandan K Saha, Kimon Zachary, Gregory K...> ;Hepatology. 2023 Aug 1
2 citations
Non-alcoholic fatty liver disease is not associated with impairment in health-related quality of life in virally suppressed persons with human immune deficiency virus.
Samer Gawrieh, Kathleen E Corey, Jordan E Lake, Niharika Samala, Archita P Desai, Paula Debroy, Julia A Sjoquist, Montreca Robison, Mark Tann, Fatih Akisik, Surya S Bh...> ;Plos One. 2023 Jan 1
Contribution of integrase inhibitor use, body mass index, physical activity and caloric intake to weight gain in people living with HIV.
Giovanni Guaraldi, Jovana Milic, Elena Bacchi, Federica Carli, Marianna Menozzi, Iacopo Franconi, Alessandro Raimondi, Giacomo Ciusa, Valentina Masi, Michela Belli, St...> ;HIV Research & Clinical Practice. 2022 Nov 22
Ectopic Fat and Cardiac Health in People with HIV: Serious as a Heart Attack.
Ana N Hyatt, Jordan E Lake> ;Current HIV/AIDS Reports. 2022 Oct 1
Anal cytology screening in men who have sex with men with HIV at a university hospital in Bogotá, Colombia.
I Tatiana Ordoñez-Blanco, Samuel Martínez-Vernaza, Kevin J Blair, Camilo Quiroga, Ellen Lowenstein, Luis J Lombana Amaya, Jesse Clark, Jordan E Lake, Sandra Liliana Va...> ;International Journal of STD & AIDS. 2022 Jun 1
3 citations
Heightened levels of plasma growth differentiation factor 15 in men living with HIV.
Neeti Agarwal, Claudia E Ramirez Bustamante, Huaizhu Wu, Reina Armamento-Villareal, Jordan E Lake, Ashok Balasubramanyam, Sean M Hartig> ;Physiological Reports. 2022 May 1
25 citations
Efficacy and safety of CD24Fc in hospitalised patients with COVID-19: a randomised, double-blind, placebo-controlled, phase 3 study.
James Welker, Juan D Pulido, Andrew T Catanzaro, Carlos D Malvestutto, Zihai Li, Jonathan B Cohen, Eric D Whitman, Dana Byrne, Olivia K Giddings, Jordan E Lake, Joel V...> ;The Lancet. Infectious Diseases. 2022 May 1
40 citations
Risk of Incident Diabetes Mellitus, Weight Gain, and Their Relationships With Integrase Inhibitor-Based Initial Antiretroviral Therapy Among Persons With Human Immunod...
Koethe, J. R., Peter F Rebeiro, Cathy A. Jenkins, Aihua Bian, Jordan E. Lake, Kassem Bourgi, Richard D. Moore, Michael A. Horberg, W. Christopher Matthews, Michael J. ...> ;Clinical Infectious Diseases. 2021 Oct 5
3 citations
Multilevel Analysis of Individual and Neighborhood Characteristics Associated with Viral Suppression Among Adults with HIV in Rio de Janeiro, Brazil.
Lyolya Hovhannisyan, Lara E Coelho, Luciane Velasque, Raquel B De Boni, Jesse Clark, Sandra W Cardoso, Jordan Lake, Valdilea G Veloso, Beatriz Grinsztejn, Paula M Luz> ;AIDS and Behavior. 2022 Mar 1
1 citations
Current Considerations for Clinical Management and Care of People with HIV: Findings from the 11th Annual International HIV and Aging Workshop
Asante R. Kamkwalala, Ankita Garg, Upal Roy, Avery Matthews, Jose R Castillo-Mancilla, Jordan E. Lake, Giada Sebastiani, Michael T. Yin, Todd T. Brown, Angela R. Kamer...> ;AIDS Research and Human Retroviruses. 2021 Sep 20
3 citations
Pre-exposure prophylaxis awareness, use, and intention to use in a regional sample of Latin American geosocial networking application users in 2018–2019:
Kevin J. Blair, Eddy R. Segura, Alex Garner, Jianchao Lai, Amy E. Ritterbusch, Sebastián León-Giraldo, Vincent Guilamo-Ramos, Jordan E. Lake, Jesse L. Clark, Ian W. Ho...> ;International Journal of STD & AIDS. 2021 Aug 2
2 citations
Poorer Muscle Quality and Quantity With ART Initiation Is Associated With Greater Inflammation and Immune Activation.
Arianna Kousari, Carlee Moser, Maxine Olefsky, Todd T. Brown, Judith S. Currier, Grace A. McComsey, Ann Scherzinger, James H. Stein, Jordan E. Lake, Kristine M. Erlandson> ;Journal of Acquired Immune Deficiency Syndromes. 2021 Dec 1
2 citations
HIV-1 Viral Protein R couples metabolic inflexibility with white adipose tissue thermogenesis
Neeti Agarwal, Dinakar Iyer, Pradip K. Saha, Aaron R. Cox, Yan Xia, Netanya S. Utay, Anoma Somasundaram, Ulrich S. Schubert, Jordan E. Lake, Sean M. Hartig, Ashok Bala...> ;Diabetes. 2021 Jul 7
1 citations
Screening With Anal Cytology in Colombia: Initial Experience and Need for High-Resolution Anoscopy.
Kevin J. Blair, Samuel Martínez-Vernaza, Ivonne Tatiana Ordóñez-Blanco, William Hernandez, Camilo Quiroga, Ellen Lowenstein, Sandra Valderrama-Beltrán, Jesse L. Clark,...> ;The Journal of Surgical Research. 2021 Jun 29
2 citations
Sexual health norms and communication patterns within the close social networks of men who have sex with men and transgender women in Lima, Peru: a 2017 cross-sectiona...
Eddy R. Segura, Amaya Perez-Brumer, Susan Chavez-Gomez, Rosario Fernandez, Jessica Gutierrez, Karla Suárez, Jordan E. Lake, Jesse L. Clark, Robinson Cabello> ;BMC Public Health. 2021 Dec 1
47 citations
Weight Change Following Antiretroviral Therapy Switch in People with Viral Suppression: Pooled Data from Randomized Clinical Trials
Kristine M. Erlandson, Christoph C Carter, Kathleen Melbourne, Todd T. Brown, C Cohen, Moupali Das, Stefan Esser, Hailin Huang, John R. Koethe, Hal Martin, Grace A. Mc...> ;Clinical Infectious Diseases. 2021 Oct 20
5 citations
Longitudinal changes in sex hormone-binding globulin in men with HIV.
Jenny Pena Dias, Sabina A. Haberlen, Adrian S. Dobs, Jordan E. Lake, Frank J. Palella, Lawrence A. Kingsley, Jennifer C. Price, Shehzad Basaria, Ravi Varadhan, Joseph ...> ;Journal of Acquired Immune Deficiency Syndromes. 2021 Aug 15
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Journal Articles

To T or Not to T: Differences in Testosterone Use and Discontinuation by HIV Serostatus Among Men Who Have Sex with Men*
T T Brown, J E Lake, W S Post, A Dobs, HIV Medicine

Hospital Affiliations

Memorial Hermann - Texas Medical CenterHouston, Texas
Memorial Hermann Physician NetworkHouston, Texas
Harris Health SystemHouston, Texas