JorgeDiPaolaMD

PubMed

• 4 citations
  Bleeding Assessment Tools in the Diagnosis of von Willebrand Disease: Systematic Review & Meta-Analysis of Test Accuracy.
  Mohamad A. Kalot, Nedaa Husainat, Sammy Tayiem, Abdallah El Alayli, Ahmad Bilal Dimassi, Osama Diab, Omar Abughanimeh, Bader Madoukh, Aref Qureini, Barbara Ameer, Jero...> ;Blood Advances. 2021 Dec 14
• 3 citations
  Whole-exome analysis of adolescents with low VWF and heavy menstrual bleeding identifies novel genetic associations.
  Brooke Sadler, Charles G. Minard, Gabe Haller, Christina A. Gurnett, Sarah H. O'Brien, Allison P. Wheeler, Shilpa Jain, Mukta Sharma, Ayesha Zia, Roshni Kulkarni, Eric...> ;Blood Advances. 2021 Nov 22
• 3 citations
  Diagnostic approach to the patient with a suspected inherited platelet disorder: Who and how to test
  Juliana Perez Botero, Jorge Di Paola> ;Journal of Thrombosis and Haemostasis. 2021 Sep 1
• 7 citations
  von Willebrand factor antigen levels are associated with burden of rare nonsynonymous variants in the VWF gene.
  Brooke Sadler, Pamela A. Christopherson, Gabe Haller, Robert R. Montgomery, Jorge Di Paola> ;Blood. 2021 Jun 10
• 1 citations
  Negatively charged nanoparticles of multiple materials inhibit shear-induced platelet accumulation.
  Michael T. Griffin, Katrina J. Ashworth, Nathaniel Hill, Jaydra von Behren, Jorge Di Paola, David N. Ku> ;Nanomedicine. 2021 Apr 28
• 6 citations
  Antithrombin deficiency: A pediatric disorder.
  Natalie Smith, Beth Boulden Warren, Julie Smith, Linda J. Jacobson, Jennifer Armstrong, Jihye Kim, Jorge Di Paola, Marilyn J. Manco-Johnson> ;Thrombosis Research. 2021 Mar 3
• 19 citations
  Platelet activation contributes to hypoxia-induced inflammation
  Cassidy Delaney, Pavel Davizon-Castillo, Ayed Allawzi, Janelle Posey, Aneta Gandjeva, Keith B. Neeves, Rubin M. Tuder, Jorge Di Paola, Kurt R. Stenmark, Eva Nozik> ;American Journal of Physiology. Lung Cellular and Molecular Physiology. 2021 Mar 1
• 6 citations
  Management of elective procedures in low von Willebrand factor patients in the LoVIC study.
  Dearbhla Doherty, Michelle Lavin, Jamie M. O’Sullivan, Kevin M. Ryan, Niamh M O'Connell, Alison Dougall, Mary Byrne, Marie Rafferty, Mairead M. Doyle, Jorge Di Paola, ...> ;Journal of Thrombosis and Haemostasis. 2021 Mar 1
• 16 citations
  von Willebrand disease: proposing definitions for future research
  Nathan T. Connell, Paula D. James, Romina Brignardello-Petersen, Rezan Abdul-Kadir, Barbara Ameer, Alice Arapshian, Susie Couper, Jorge Di Paola, Jeroen Eikenboom, Nic...> ;Blood Advances. 2021 Jan 26
• 12 citations
  Specifications of the variant curation guidelines for ITGA2B/ITGB3: ClinGen Platelet Disorder Variant Curation Panel.
  , , , , , , , , , , , , , , , , , > ;Blood Advances. 2021 Jan 26
• 184 citations
  ASH ISTH NHF WFH 2021 guidelines on the diagnosis of von Willebrand disease
  Paula D. James, Nathan T. Connell, Barbara Ameer, Jorge Di Paola, Jeroen Eikenboom, Nicolas Giraud, Sandra L. Haberichter, Vicki Jacobs-Pratt, Barbara A. Konkle, Clair...> ;Blood Advances. 2021 Jan 12
• 4 citations
  ETV6-related thrombocytopenia and platelet dysfunction.
  Jorge Di Paola, Marlie H. Fisher> ;Platelets. 2021 Jan 2
• 23 citations
  Hemostasis vs. homeostasis: Platelets are essential for preserving vascular barrier function in the absence of injury or inflammation.
  Shuchi Gupta, Christoph Konradt, Adam Corken, Jerry Ware, Bernhard Nieswandt, Jorge Di Paola, Mei Yu, Demin Wang, Marvin T. Nieman, Sidney W. Whiteheart, Lawrence F. B...> ;Proceedings of the National Academy of Sciences of the United States of America. 2020 Sep 29
• 12 citations
  ETV6 germline mutations cause HDAC3/NCOR2 mislocalization and upregulation of interferon response genes
  Marlie H. Fisher, Gregory Kirkpatrick, Brett M. Stevens, Courtney L. Jones, Michael U. Callaghan, Madhvi Rajpurkar, Joy M. Fulbright, Megan A. Cooper, Jesse W. Rowley,...> ;JCI Insight. 2020 Sep 17
• 8 citations
  Platelet α-granules are required for occlusive high-shear-rate thrombosis
  Dongjune Kim, Katrina J. Ashworth, Jorge Di Paola, David N. Ku> ;Blood Advances. 2020 Jul 28
• 4 citations
  Hypermethioninemia Leads to Fatal Bleeding and Increased Mortality in a Transgenic I278T Mouse Model of Homocystinuria.
  Insun Park, Linda K. Johnson, Allaura Cox, Brian R. Branchford, Jorge Di Paola, Erez M. Bublil, Tomas Majtan> ;Biomedicines. 2020 Jul 24
• 3 citations
  Pathologic Shear and Elongation Rates Do Not Cause Cleavage of Von Willebrand Factor by ADAMTS13 in a Purified System.
  Maria Bortot, Alireza Sharifi, Katrina J. Ashworth, Faye Walker, Allaura Cox, Katherine Ruegg, Nathan Clendenen, Keith B. Neeves, David Bark, Jorge Di Paola> ;Cellular and Molecular Bioengineering. 2020 Jul 17
• 50 citations
  Glanzmann thrombasthenia: genetic basis and clinical correlates.
  Juliana Perez Botero, Kristy Lee, Brian R. Branchford, Paul F. Bray, Kathleen Freson, Michele P. Lambert, Minjie Luo, Shruthi Mohan, Justyne Ross, Wolfgang Bergmeier, ...> ;Haematologica. 2020 Apr 1
• 11 citations
  Platelet activation in experimental murine neonatal pulmonary hypertension.
  Pavel Davizon-Castillo, Ayed Allawzi, Matthew G. Sorrells, Susan Fisher, Kristina Baltrunaite, Keith B. Neeves, Eva Nozik-Grayck, Jorge DiPaola, Cassidy Delaney> ;Physiological Reports. 2020 Mar 1
• 27 citations
  Pro-inflammatory cytokine blockade attenuates myeloid expansion in a murine model of rheumatoid arthritis
  , , , , , , , , , , , , , , , , , , , > ;Haematologica. 2020 Mar 1
• 20 citations
  A mathematical model of coagulation under flow identifies factor V as a modifier of thrombin generation in hemophilia A
  Kathryn G. Link, Michael T. Stobb, Matthew G. Sorrells, Maria Bortot, Katherine Ruegg, Marilyn J. Manco-Johnson, Jorge Di Paola, Suzanne Sindi, Aaron L. Fogelson, Kari...> ;Journal of Thrombosis and Haemostasis. 2020 Feb 1
• 12 citations
  Behavior, body composition, and vascular phenotype of homocystinuric mice on methionine-restricted diet or enzyme replacement therapy
  Tomas Majtan, Insun Park, Allaura Cox, Brian R. Branchford, Jorge Di Paola, Erez M. Bublil, Jan P. Kraus> ;FASEB Journal. 2019 Nov 1
• 152 citations
  TNF-α–driven inflammation and mitochondrial dysfunction define the platelet hyperreactivity of aging
  Pavel Davizon-Castillo, Brandon McMahon, Sonia Aguila, David Bark, Katrina J. Ashworth, Ayed Allawzi, Robert A. Campbell, Emilie Montenont, Travis Nemkov, Angelo D'Ale...> ;Blood. 2019 Aug 29
• 38 citations
  ETV6-related thrombocytopenia and leukemia predisposition
  Jorge Di Paola, Christopher C. Porter> ;Blood. 2019 Aug 22
• 28 citations
  Turbulent Flow Promotes Cleavage of VWF (von Willebrand Factor) by ADAMTS13 (A Disintegrin and Metalloproteinase With a Thrombospondin Type-1 Motif, Member 13).
  Maria Bortot, Katrina J. Ashworth, Alireza Sharifi, Faye Walker, Nathan Crawford, Keith B. Neeves, David Bark, Jorge Di Paola> ;Arteriosclerosis, Thrombosis, and Vascular Biology. 2019 Jul 11
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Journal Articles

• Novel Gas6/TAM inhibitors decrease platelet activation and prevent thrombosis  
  Branchford B.R., Stalker T.J., Law L., Acevedo G., Sather S., Brzezinski C., Liu Y., White-Adams T.C., Wilson K.M., Molk D., Salzberg D.B., Zhang W., Liu J., Stashko ..., Journal of Thrombosis and Haemostasis, 1/24/2017
• Tamoxifen Suppresses Platelet Activation-Supported Angiogenesis and Metastasis  
  Davizon-Castillo, P., Di Paola, J., Arterioscler Thromb Vasc Biol, 1/1/2017
• Limit of detection and threshold for positivity of the Centers for Disease Control and Prevention assay for factor VIII inhibitors  
  Miller CH, Boylan B, Shapiro AD, Lentz SR, Wicklund BM; Hemophilia Inhibitor Research Study Investigators, J Thromb Haemost, 1/1/2017
• Chitinase 3-like-1 promotes intrahepatic coagulation through induction of tissue factor in mice  
  Shan Z., Liu X., Chen Y, Wang M, Gao Y.R., Xu L., Davizon Castillo P., Di Paola J and Ju C., Hepatology, 1/1/2017
• A Microfluidic of Hemostasis Sensitive to Platelet Function and Coagulation  
  Schoeman R.M., Rana K., Danes, N., Lehman M., Di Paola J., Fogelson A.L., Leiderman K., Cell Mol Bioeng, 1/1/2017
• Genetic Regulation of Ectonucleoside Triphosphate Diphosphohydrolase-1 (NTPDase1) Activity  
  Maloney J.P., Branchford, B.R., Brodsky G.L., Cosmic, M.S. Calabrese, D.W., Aquilante, C.L., Maloney, K.W., Gonzalez, J.R., Zhang, W., Moreau, K.L., Wiggins, K.L., S..., FASEB J, 1/1/2017
• Peptides derived from MARCKS block coagulation protein complex assembly on phosphatidylserine and inhibit fibrin formation  
  Kastelowitz N., Onasoga A., Stalker T.J., White R.O., Brown P.N., Brodsky G.L., Tamura R., Lawrence F. Brass L.F., Branchford B.R., Di Paola J., and Hang Yin H., Sci Rep, 1/1/2017
• Evaluation of a microfluidic flow assay to screen for von Willebrand disease and low von Willebrand factor levels  
  Lehmann M, Ashworth K, Manco-Johnson M, Di Paola J, Neeves K, Ng CJ, Journal of Thrombosis and Haemostasis, 1/1/2017
• Variable bleeding phenotype in an Amish pedigree with von Willebrand disease  
  Gupta S., Heiman M., Duncan N., Hinckley J.D., Di Paola J., Shapiro A.D., Am J Hematol, 1/14/2016
• Hemophilia Inhibitor Research Study Investigators Survey of the anti-factor IX immunoglobulin profiles in patients with hemophilia B using a fluorescence-based immunoa...  
  Boylan B., Rice A.S., Neff A.T., Manco-Johnson M.J., Kempton C.L., Miller C.H., J Thromb Haemost, 1/8/2016
• Platelet abnormalities in a family with von Willebrand disease type 2B (V1316M) and association with bleeding score  
  Guglielmoni H., Smith N., Minoldo S., Jarchum G.D., White-Adams T.C., Di Paola J., Haemophilia, 1/7/2016
• Mutations in the D’D3 region of VWF traditionally associated with type 1 VWD lead to quantitative and qualitative deficiencies of VWF  
  White-Adams T.C., Ng C.J., Jacobi P.M., Haberichter S.L., Di Paola J., Thrombosis Research, 1/1/2016
• Microangiopathic hemolytic anemia due to ADAMTS-13 loss in idiopathic systemic capillary leak syndrome  
  Moreira D.C., Ng C.J., Quinones R., Liang X., Chung DW, Di Paola J., J Thromb Haemost, 1/1/2016
• Platelet Type von Willebrand Disease and registry Report: Communication from the VWF and Platelet Physiology Subcommittees of the ISTH  
  Othman M., Kaur H., Favaloro E.J., Lillicrap D., Di Paola J., Harrison P., Gresele P., J Thromb Haemost, 1/1/2016
• Shear-induced unfolding of mechanosensory domain in GPIb-IX induces platelet Clearance  
  Deng W., Xu Y., Chen W., Paul D.S., Syed A.K., Dragovich M.A., Xin Liang,1 Philip Zakas,1 Berndt M.C., Di Paola J., Ware J., Lanza F., Christopher B. Doering C.B., Ber..., Nat Commun, 1/1/2016
• Paris-Trousseau: evidence keep pointing to FLI1  
  Di Paola J, Blood, 1/22/2015
• Characterization of the anti-factor VIII immunoglobulin profile in patients with hemophilia A by use of a fluorescence-based immunoassay  
  Boylan B, Rice AS, Dunn AL, Tarantino MD, Brettler DB, Barrett JC, Miller CH; Hemophilia Inhibitor Research Study Investigators; Hemophilia Inhibitor Research Study In..., J Thromb Haemost, 1/1/2015
• Differential VWF mutant monomer incorporation drives the phenotypic variability observed  
  Chen J., Hinckley J.D., Haberichter S., Jacobi P., Montgomery R., Flood V.H., Wong R., Interlandi G., Chung D.W., Lopez J.A., Di Paola J., Blood, 1/1/2015
• Subcommittee on von Willebrand factor Platelet dependent von Willebrand factor activity Nomenclature and methodology: communication from the SSC of the ISTH  
  Bodo I., Eikenboom J., Montgomery R., Patzke J., Schneppenheim R., Di Paola J., J Thromb Haemost, 1/1/2015
• Microfluidic technology as an emerging clinical tool to evaluate thrombosis and hemostasis  
  Branchford B.R., Ng C.J., Neeves K.B., and Di Paola J., Thromb Res, 1/1/2015
• Germline mutations in ETV6 are associated with thrombocytopenia, red cell macrocytosis and predisposition to lymphoblastic leukemia  
  Noetzli L., Lo R.W., Lee-Sherick A.B., Callaghan M., Noris P., Savoia A., Rajpurkar M., Jones K., Gowan K., Balduini C., Pecci A., Gnan C., De Rocco D., Doubek M., Li ..., Nat Genet, 1/1/2015
• Platelets join the world of “Omics”  
  Boulden-Warren B. and Di Paola J., Blood, 1/1/2014
• Red Blood Cell Retention in Venous Thrombosis Requires Factor XIII Activity  
  Aleman M.M., Byrnes J.R., Wang J., Tran R., Lam W.A., Di Paola J, Mackman N., Degen J.L., Flick M.J., Wolberg A.S., Journal of Clinical Investigation, 1/1/2014
• Genetic Basis of Congenital Platelet Disorders  
  Hinckley J, Di Paola J, Hematology Am Soc Hematol Educ Program, 1/1/2014
• Understanding Congenital Platelet Disorders  
  Di Paola J, Clin Adv Hematol Oncol, 1/1/2014
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Books/Book Chapters

• Bone Marrow Failures. 
  Chapter: Inherited Thrombocytopenias 
  Nakano T. and Di Paola J.Editors: Kupfer, Reaman and Smith.SpringerEdition 1st,2017
• Trauma Induced Coagulopathy. 
  Chapter: Platelet Aggregometry 
  Nakano T. and Di Paola J.Editors: Gonzalez, Moore and Moore.SpringerEdition 1st,2016
• SickKids Handbook of Pediatric Thrombosis and Hemostais. 
  Chapter: Genetic Testing and Counseling for Pediatric Inherited Bleeding and Clotting Disorders 
  Babul-Hirji, Di Paola J and Lillicrap DEditors: Blanchette V., Brandao L., Breaky V. and Revel-Vick S..KargerEdition 2nd,2016
• American Society of Hematology Self Assessment Program. 
  Chapter: Bleeding Disorders 
  Kempton C. and Di Paola J.ASH-SAP2016
• Nathan and Oski’s Hematology of Infancy and Childhood. 
  Chapter: Approach to the Bleeding Child 
  Branchford B. and Di Paola J.Editors: Orkin SH, Ginsburg D, Nathan DG, Look AT, Fisher DE, and Lux SE.Elsevier, Cambridge, MAEdition 8th,2015
• Nathan and Oski's Hematology of Infancy and Childhood. 
  Chapter: Hemophilia and Von Willebrand Disease 
  Di Paola J., Montgomery R., Gill J.C. and Flood V.Editors: Orkin SH, Ginsburg D, Nathan DG, Look AT, Fisher DE, and Lux SE.Elsevier, Cambridge, MAEdition 8th,2015
• American Society of Hematology Self-Assessment Program. 
  Chapter: Bleeding Disorders 
  Di Paola J. and Shapiro AASH-SAP2013
• American Society of Hematology Education Book 
  Chapter: Making a diagnosis of Von Willebrand Disease. 
  Page 161 - 167Branchford B., Di Paola J.2012
• Consultative Hemostasis and Thrombosis. New Edition 
  Chapter: Congenital and acquired disorders of platelet function 
  Jobe S. and Di Paola JEditors: Kitchens, Alving, Kessler.2012
• Von Willebrand Disease 
  Chapter: Pediatrics Aspect of Von Willebrand Disease 
  Di Paola J. and Thomas AbshireEditors: Augusto Federici, Christine Lee, Erik Berntop, David Lillicrap and Robert Montgomery.Willey-Blackwell2011
• Nathan and Oski’s Hematology of Infancy and Childhood. 
  Chapter: Hemophilia and Von Willebrand Disease 
  Montgomery R., Gill J.C., and Di Paola J.Editors: Orkin SH, Ginsburg D, Nathan DG, Look AT, Fisher DE, and Lux SE.Elsevier, Cambridge, MAEdition 7th,2009
• Consultative Hemostasis and Thrombosis. 
  Chapter: Congenital and acquired disorders of platelet function 
  Jobe S. and Di Paola JEditors: Kitchens, Alving, Kessler.2007
• Handbook of Pediatric Tranfusion. 
  Chapter: Transfusion of the Pediatric Surgery, Trauma, and Intensive Care Unit Patient 
  Raife T.J. and Di Paola JEditors: Hylliard, Strauss, Luban.Elsevier2004
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Abstracts/Posters

• Modulation of Thrombin-Induced Platelet Activation By Defibrotide
  Jorge Di Paola, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
• Aging-Associated Inflammation Due to Elevated Levels of TNF-alpha Increases Activation of the Integrin alphaIIbbeta3 and the Procoagulant Potential of Platelets.
  Davizon-Castillo P., Jones K.L., Aguila S., Bark, D, Ashworth K. J., Higa K., Pietras E.M., Campbell R. A., Shih L.C., Saunders N., DeGregori J., Rondina M.T. and Di P..., American Society of Hematology Meeting, Atlanta, GA, 1/1/2017
• Endothelial Colony Forming Cells from Individuals with Low VWF Levels Demonstrate Impairment in Stimulated VWF Release.
  Ng C.J., Ashworth K., White-Adams T., Di Paola J., American Society of Hematology Meeting, Atlanta, GA, 1/1/2017
• Effect of elongational flow on von Willebrand Factor cleavage by ADAMTS13.
  Bortot MB, Bark D Jr, Neeves KB, Leiderman K, Fogelson A, Aguila Martinez S, Ng CJ, Di Paola J., International Society of Thrombosis and Haemostasis Meeting, Berlin, Germany, 1/1/2017
• Pro-Inflammatory Cytokines Drive the Development of a Prothrombotic Platelet Phenotype in Inflammation and Aging.
  Davizon-Castillo P., Aguila S., Higa K. , Ashworth K. J., Hernandez G., Bark D., Campbell R.A., Rondina M., DeGregori J., Di Paola J. and Pietras E.M., American Society of Hematology Annual Meeting, San Diego, CA, 1/1/2016
• Multi-system evaluation of von Willebrand factor function in Type 1 von Willebrand disease mutations.
  Ng C., Ashworth K. , Manco-Johnson M., White-Adams T. C., Di Paola J, Gordon Research Conference, Hemostasis, Stowe, VT, 1/1/2016
• Aging-associated Inflammation Promotes the Development of a Platelet Prothrombotic Phenotype.
  Davizon-Castillo P., Ashworth K.J., Higa K., Hernandez G., Campbell R.A., Rondina M.T., . Collins C.B., Donato A.J., Lesniewski L.A., DeGregori J., Pietras E.M. and Di..., Hemostasis Gordon Research Conference, Stoweflake, VT, 1/1/2016
• The Use of a Novel Microfluidic Assay to Evaluate Von Willebrand Disease and Mucocutaneous Bleeding.
  Ng, C.J., Lehman M., Manco-Johnson M., Neeves K.B., Di Paola J., Hemostasis and Thrombosis Research Society, New Orleans, LA, 1/1/2015
• MARCKS ED Inhibits Fibrin Formation By Blocking Coagulation Protein Complex Assembly on Phosphatidylserine.
  Kastelowitz N., Jarvis A., White O.R., Brown P.N., Brodsky G., Tamura R., Di Paola J., and Yin H., American Society of Hematology Annual Meeting, Orlando, FL, 1/1/2015
• A Novel Microfluidic Assay to Determine Von Willebrand Factor Levels and Bleeding Phenotypes in Patients with Von Willebrand Disease and Mucocutaneous Bleeding
  Ng C.J., Lehman M., Manco-Johnson M., Neeves K.B., and Di Paola J.A., American Society of Hematology Annual Meeting, Orlando, FL, 1/1/2015
• A Dominant Negative Mutation (p.P214L) in ETV6 is Associated with Megakaryocyte and Erythroid Transcript Misregulation.
  Noetzli L., Rowley J.W., Callaghan M.U., Rajpurkar M., Lee-Sherick A.B., Porter C.C., Weyrich A.S., and Di Paola J., American Society of Hematology Annual Meeting, Orlando, FL, 1/1/2015
• A Novel Small Molecule Inhibitor of the Gas6/TAM Pathway, in Combination with ADP/P2Y Antagonists, Mediate Synergistic Inhibition of Platelet Aggregation and Decreases...
  Branchford B., Law L., Acevedo G., Brzezinski C., Sather S., Brodsky G., DeRyckere D., Zhang W., Earp H.S., Frye S., Graham D.K., Di Paola J., Thrombosis and Hemostasis Summit of North America, Chicago, IL, 1/1/2014
• Human Anti-beta2-GPI Antibodies Increase the Release of Soluble and Cell Surface Anchored Von Willebrand Factor from Human Endothelial Cells
  Ng C.J., McCrae K.R., Chen J., Wang M., Manco-Johnson M., White-Adams T.C., Lopez J.A., Di Paola J., Thrombosis and Hemostasis Summit of North America, Chicago, IL, 1/1/2014
• Inhibition of the Gas/Mer Pathway with novel compounds recapitulates the antithrombotic phenotype of Gas6-/- or Mer -/- mice in arterial and venous thrombosis models.
  Branchford B.R., Law L., Sather S., DeRyckere D., Brodsky G., Earp H.S., Wang X., Frye S., Graham D.K., Di Paola J., International Society of Thrombosis/Hemostasis annual meeting, Amsterdam, Netherlands, 1/1/2013
• Human Apolipoprotein A-1 decreases platelet activation responses and protects mice from arterial thrombosis.
  Branchford B.R., Ramos C., Moore E., Jones W., Silliman C., Banerjee A., Di Paola J., Haemophilia; Hemostasis and Thrombosis Research Society Annual Meeting, Charlotte, NC, 1/1/2013
• Novel Small Molecule Inhibitors Of The Gas6/TAM Signaling Pathway Inhibit Platelet Aggregation In Vitro and Protect Mice From Arterial and Venous Thrombosis In Vivo
  Acevedo G., Branchford B., Law L., Brzezinski C., Sather S., Brodsky G., DeRyckere D., Zhang W., Liu J., Earp H.S., Frye S., Graham D.K., Di Paola J., American Society of Hematology annual meeting, New Orleans, LA, 1/1/2013
• Novel Small Molecule Inhibitors Of The Gas6/TAM Signaling Pathway Mediate Synergistic Inhibition Of Platelet Aggregation In Combination With ADP/P2Y Antagonists
  Branchford B., Law L., Acevedo G., Brzezinski C., Sather S., Brodsky G., DeRyckere D., Zhang W., Earp H.S., Frye S., Graham D.K., Di Paola J., American Society of Hematology annual meeting, New Orleans, LA, 1/1/2013
• Injury induced increase in Apolipoprotein A-1 decreases platelet activation responses and protects mice from arterial and venous thrombosis.
  Ramos C., Jones W., Moore E., Branchford B.R., Di Paola J., Silliman C., Banerjee A., Shock; Shock Society annual meeting, San Diego, CA, 1/1/2013
• A small molecule inhibitor of Gas6/Mer Pathway inhibits platelet activation and thrombosis with equal efficacy to, but greater potency that, iMer, the novel MerTK Spli...
  Branchford B., Law L., Sather S., Brodsky G., Earp III H.S, Wang X., Frye S., Graham D. and Di Paola J., 54th annual American Society of Hematology annual meeting, Atlanta, GA, 1/1/2012
• A new microfluidicbased platelet rolling assay to better characterize VWD phenotypes.
  White-Adams T.C., Jacobi P., Haberichter S.L, Neeves K., and Di Paola J., 54th annual American Society of Hematology annual meeting, Atlanta, GA, 1/1/2012
• A novel splice variant of the Mer receptor tyrosine kinase functions as an inhibitor of the Gas6/TAM signaling pathway and decreases platelet activation responses.
  Branchford B., Sather S., Brodsky G., White-Adams T., DeRyckere D., Neeves K., Graham D., Di Paola J., International Society of Thrombosis and Hemostasis, Kyoto, Japan, 1/1/2011
• Imer Blocks Phosphorylation of the beta3 Integrin, Decreasing Platelet Activation Responses and Protecting Mice From Arterial Thrombosis.
  Branchford B.R., Sather S., Brodsky G., White-Adams T.C., DeRyckere D., Neeves K.B., Wilson K.M., Lentz S.R., Graham D.K., and Di Paola J.A., 53rd Annual Meeting, American Society of Hematology, San Diego, CA, 1/1/2011
• A Novel Missense Mutation in FGG (c.944C>A) Encodes for An Amino Acid Change (p.Ala315Asp) in the Gamma Chain of Fibrinogen Causing Hypofibrinogenemia and a Thrombo...
  Larissa Bornikova, Gary Brodsky, Keith B Neeves, Rita Marchi, Donald S Backos, Philip Reigan, Alisa S. Wolberg, Marilyn J. Manco-Johnson and Jorge A Di Paola, 53rd Annual Meeting, American Society of Hematology, San Diego, CA, 1/1/2011
• Molecular Analysis of Type 1 VWD Mutations: Effects of Mutant:Wild-Type Transfection Ratio and Protein Degradation.
  White-Adams T.C., Jacobi P.M., Haberichter S.L., and Di Paola J.A., 53rd Annual Meeting, American Society of Hematology, San Diego, CA, 1/1/2011
• Quantitative Trait Loci for Von WIllebrand Factor Levels in a Large Pedigree with Von Willebrand Disease.
  Di Paola J., Abbot D., Wang K., Hinckley J., Murray J., Nixon B., Burns T., and Shapiro A., XXII meeting of the International Society of Thrombosis and Hemostasis, Boston, MA, 1/1/2009
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Lectures

• Approach to Diagnosis and Management of Patients with Congenital Platelet Disorders 
  61st Annual American Society of Hematology Meeting - Orlando, FL - 12/7/2019
• Hemostasis and Thrombosis Poster Walk for Trainees 
  61st Annual American Society of Hematology Meeting - Orlando, FL - 12/7/2019
• Single-Cell RNA-Seq Analysis of Native Murine Megakaryocytes from Young and Old Mice Reveals Significant Metabolic and Mitochondrial Differences throughout Megakaryocy... 
  2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
• TNF-α Driven Inflammation and Mitochondrial Dysfunction Characterize the Platelet Hyperreactivity of Aging and Myeloproliferative Neoplasms (MPN) 
  2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
• Team Science 
  University of Colorado School of Medicine - 1/11/2018
• Studying Megakaryocytes, from inherited disorders to aging platelets 
  University of Rochester, Rochester, NY - 1/17/2017
• Genetics of Pediatric Bleeding Disorders 
  Berlin, Germany - 1/13/2017
• Leukemia Modeling Workshop 
  1/12/2017
• Disorders of Hemostasis 
  Hong Kong, China, 2017; Punta del Este, Uruguay, 2017 - 1/8/2017
• Disorders of Platelets and von Willebrand Factor 
  Boston, MA - 1/5/2017
• A novel murine model of an ETV6 germline mutation 
  1/1/2017
• Genomics of Congenital Bleeding Disorders 
  Children’s Mercy Hospital, Kansas City, MO - 1/25/2016
• My patient is bleeding: What is the cause? 
  Children’s Hospital of Michigan, 2012; Children’s Hospital of Alabama, Birmingham, AL, 2016 - 1/20/2016
• From the bedside to the bench: genomics of disorders of hemostasis 
  Adairsville, GA - 1/16/2016
• Genetics of von Willebrand Disease 
  St. James Hospital and Trinity College, Dublin, Ireland - 1/8/2016
• Genomics of Platelet Disorders 
  University of Utah, Salt Lake City, UT - 1/5/2016
• Novel Congenital Platelet Disorders 
  San Diego, CA - 1/3/2016
• Genetics of Congenital Bleeding Disorders 
  San Diego, CA - 1/3/2016
• Pathophysiology of von Willebrand Disease 
  1/30/2015
• Genetics of Congenital Platelet Disorders 
  Buenos Aires, Argentina - 1/24/2014
• Microfluidics for Hemostatic testing under Physiologic Conditions 
  1/16/2014
• Genetic Approaches to Disorders of Hemostasis 
  Children’s Hospital Colorado and University of Colorado School of Medicine - 1/14/2014
• Genomics Approaches to Disorders of Hemostasis 
  University of Iowa, Iowa City, IA, 2014 - 1/10/2014
• Microfluidic Assessment of Platelet Function 
  Madrid, Spain - 1/8/2014
• Von Willebrand Disease, diagnosis and treatment 
  Guadalajara, Mexico - 1/2/2014
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Other

• Understanding Hemophilia 
  Di Paola J., Healthy Body, Healthy Mind, ITN
  http://www.itvisus.com/programs/hbhm/episode_1002_Understanding_Hemophilia.asp
  1/1/2008
• Von Willebrand Disease 
  Di Paola J, Hematology Web Focus, American Society of Hematology (ASH)
  http://www.hematologylibrary.org/webfocus/