JoseAngelBufillMD

Oncology • Bremen, IN

Director of the Cancer Genetics Program at Saint Joseph Regional Medical Center in Mishawaka

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Office
1020 High Rd
Bremen, IN 46506
Phone+1 574-546-2211
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Education & Training

New York Medical College at St Vincent's Hospital and Medical Center of New YorkFellowship, Hematology and Medical Oncology, 1990 - 1991
Medical College of Wisconsin Affiliated HospitalsFellowship, Hematology and Medical Oncology, 1986 - 1988
Medical College of Wisconsin Affiliated HospitalsResidency, Internal Medicine, 1983 - 1986
Universidad de Navarra Faculty of MedicineClass of 1983

Certifications & Licensure

IN State Medical License 1993 - 2025
MI State Medical License 2011 - 2018
WI State Medical License 1985 - 1989
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Medical Oncology

Awards, Honors, & Recognition

Fellow (FACP) American College of Physicians, 1999

Clinical Trials

Androgen Ablation Therapy With or Without Chemotherapy in Treating Patients With Metastatic Prostate Cancer Start of enrollment: 2006 Sep 26
Active, not recruiting
Phase 3
Cisplatin + Etoposide +/- Concurrent ZD6474 in Previously Untreated Extensive Stage Small Cell Lung Cancer Start of enrollment: 2008 Jan 01
Completed
Phase 2
BLP25 Liposome Vaccine and Bevacizumab After Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Stage IIIA or Stage IIIB Non-Small Cell Lung Cancer That Cannot Be Removed by Surgery Start of enrollment: 2011 Jan 17
Completed
Phase 2
PARP Inhibition for Triple Negative Breast Cancer (ER-/PR-/HER2-)With BRCA1/2 Mutations Start of enrollment: 2010 Feb 01
Completed
Phase 2
Tamoxifen Citrate in Treating Patients With Metastatic or Recurrent Breast Cancer Start of enrollment: 2011 Jan 07
Completed
Phase 2
Sunitinib Malate With or Without Gemcitabine Hydrochloride in Treating Patients With Advanced Kidney Cancer That Cannot Be Removed By Surgery Start of enrollment: 2010 Sep 17
Completed
Phase 2
Early Surgery or Standard Palliative Therapy in Treating Patients With Stage IV Breast Cancer Start of enrollment: 2011 May 16
Completed
Not Applicable
Ipilimumab or High-Dose Interferon Alfa-2b in Treating Patients With High-Risk Stage III-IV Melanoma That Has Been Removed by Surgery Start of enrollment: 2011 May 25
Active, not recruiting
Phase 3
Cisplatin and Etoposide With or Without Veliparib in Treating Patients With Extensive Stage Small Cell Lung Cancer Start of enrollment: 2012 Sep 28
Completed
Phase 1, Phase 2
Rituximab and Combination Chemotherapy With or Without Lenalidomide in Treating Patients With Newly Diagnosed Stage II-IV Diffuse Large B Cell Lymphoma Start of enrollment: 2013 Aug 27
Active, not recruiting
Phase 2
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Publications & Presentations

PubMed

Type B Lactic Acidosis in a Patient with Mantle Cell Lymphoma.
Ikemsinachi C Nzenwa, Margaret Berquist, Toby J Brenner, Aida Ansari, Hamid D Al-Fadhl, Michael Aboukhaled, Shivani S Patel, Ethan E Peck, Mahmoud D Al-Fadhl, Anthony ...> ;Case Reports in Critical Care. 2023 Jan 1
ASCO Voices 2020.
Daniel Rayson, Jose A. Bufill, Julia Close, Alice Cyusa, Kurt R. Oettel, Onyemaechi Okolo, Aparna Raj Parikh, Lidia Schapira> ;Journal of Clinical Oncology. 2020 Aug 9
28 citations
Genomic profiling of cell-free circulating tumor DNA in patients with colorectal cancer and its fidelity to the genomics of the tumor biopsy
Gerald Li, Dean Pavlick, Jon Chung, Todd M. Bauer, Bradford A. Tan, Julio Peguero, Patrick Ward, Andre Kallab, Jose A. Bufill, Anthony Hoffman, Ahad Sadiq, Jeff Edenfi...> ;Journal of Gastrointestinal Oncology. 2019 Oct 1
139 citations
Diverse EGFR Exon 20 Insertions and Co-Occurring Molecular Alterations Identified by Comprehensive Genomic Profiling of NSCLC.
Jonathan W. Riess, David R. Gandara, Garrett M. Frampton, Russell Madison, Nir Peled, Jose A. Bufill, Grace K. Dy, Sai-Hong Ignatius Ou, Philip J. Stephens, John Dougl...> ;Journal of Thoracic Oncology. 2018 Oct 1
893 citations
STK11/LKB1 Mutations and PD-1 Inhibitor Resistance in KRAS-Mutant Lung Adenocarcinoma.
, , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , > ;Cancer Discovery. 2018 May 17
50 citations
Patient-reported predictors of early treatment discontinuation: treatment-related symptoms and health-related quality of life among postmenopausal women with primary b...
Lynne I. Wagner, Fengmin Zhao, Paul E. Goss, Judith Anne W. Chapman, Lois E. Shepherd, Timothy J. Whelan, Bassam I. Mattar, Jose A. Bufill, William C. Schultz, Irving ...> ;Breast Cancer Research and Treatment. 2018 Feb 17
108 citations
Pulmonary Sarcomatoid Carcinomas Commonly Harbor Either Potentially Targetable Genomic Alterations or High Tumor Mutational Burden as Observed by Comprehensive Genomic...
Alexa B. Schrock, Shuyu D. Li, Garrett M. Frampton, James Suh, Eduardo Braun, Ranee Mehra, Steven C. Buck, Jose A. Bufill, Nir Peled, Nagla Abdel Karim, K. Cynthia Hsi...> ;Journal of Thoracic Oncology. 2017 Jun 1
517 citations
Activation of MET via diverse exon 14 splicing alterations occurs in multiple tumor types and confers clinical sensitivity to MET inhibitors
Garrett M. Frampton, Siraj M. Ali, Margaret Rosenzweig, Juliann Chmielecki, Xinyuan Lu, Todd M. Bauer, Mikhail Akimov, Jose A. Bufill, Carrie B. Lee, David Jentz, Rick...> ;Cancer Discovery. 2015 May 13
Phase II Trial of Erlotinib and Docetaxel in Advanced and Refractory Hepatocellular and Biliary Cancers: Hoosier Oncology Group GI06-101.
Chiorean, E. G., Ramasubbaiah, R., Yu, M., Picus, J., Bufill, J. A., Tong, Y., Coleman, N., Johnston, E. L., Currie, C., Loehrer, P. J.> ;Oncologist. 2012 Jun 06
16 citations
Phase II and gene expression analysis trial of neoadjuvant capecitabine plus irinotecan followed by capecitabine-based chemoradiotherapy for locally advanced rectal ca...
E. Gabriela Chiorean, Sonal P. Sanghani, Marissa A. Schiel, Menggang Yu, Matthew Burns, Yan Tong, David T. Hinkle, Nicki Coleman, Bruce W. Robb, Julia K. Leblanc, Romn...> ;Cancer Chemotherapy and Pharmacology. 2012 May 18
55 citations
Phase II Trial of Erlotinib and Docetaxel in Advanced and Refractory Hepatocellular and Biliary Cancers: Hoosier Oncology Group GI06-101
E. Gabriela Chiorean, Rashmi Ramasubbaiah, Menggang Yu, Joel Picus, Jose A. Bufill, Yan Tong, Nicki Coleman, Erica L. Johnston, Colleen Currie, Patrick J. Loehrer> ;The Oncologist. 2012 Jan 1
Phase I study of everolimus (RAD001) with irinotecan (Iri) and cetuximab (C) in second-line metastatic colorectal cancer (mCRC): Hoosier Oncology Group GI05-102-Final ...
Shahda S, Yu M, Picus J, Bufill JA, Harb WA, Burns M, Spittler AJ, Flynn J, Zeng Y, Vance GH, Wu J, Currie CR, Loehrer PJ, Chiorean EG> ;J. Clin. Oncol.. 2011-05-20
Phase I study of everolimus (RAD001) with irinotecan (Iri) and cetuximab (C) in second-line metastatic colorectal cancer: Hoosier Oncology Group GI05-102.
Myre B, Yu M, Picus J, Bufill JA, Harb WA, Burns M, Spittler AJ, Zeng Y, Currie CR, Chiorean EG> ;J. Clin. Oncol.. 2011-02-01
64 citations
Phenotypic expression of disease in families that have mutations in the 5' region of the adenomatous polyposis coli gene
Francis M. Giardiello, Jill D. Brensinger, Michael C. Luce, Gloria M. Petersen, Matthew C. Cayouette, Anne J. Krush, Judith A. Bacon, Susan V. Booker, Jose A. Bufill, ...> ;Annals of Internal Medicine. 1997 Apr 1
11 citations
Amyl nitrite-induced hemolytic anemia
James C. Brandes, Jose A. Bufill, Anthony V. Pisciotta> ;The American Journal of Medicine. 1989 Jan 1
27 citations
Pityrosporum folliculitis after bone marrow transplantation. Clinical observations in five patients.
Jose A. Bufill, Lawrence G. Lum, James G. Caya, Christopher R. Chitambar, Paul S. Ritch, Tom Anderson, Robert C. Ash> ;Annals of Internal Medicine. 1988 Apr 1
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Press Mentions

American Oncologist to Conduct Lecture on Lymphoma & Breast Cancer TreatmentJanuary 4th, 2019
Mini Medical School Lecture Series Starts Wednesday at IU School of MedicineMarch 9th, 2017
A Vision of HopeMarch 1st, 2024