
Jose C Florez MD PhD
Diabetes, Lipid Metabolism
Physician-in-Chief and Chair, Department of Medicine - Massachusetts General Hospital, Harvard Medical School
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75 Francis StBoston, MA 02115
Phone+1 617-732-5500
Fax+1 617-724-8534
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Summary
- Dr. Jose Florez is an endocrinologist in Boston, MA and is affiliated with Massachusetts General Hospital. He received his medical degree from Northwestern University Feinberg School of Medicine and has been in practice 20 years. He specializes in diabetes and lipid metabolism.
Education & Training
Mass General Brigham/Massachusetts General HospitalFellowship, Endocrinology, Diabetes, and Metabolism, 2001 - 2004
Massachusetts General HospitalInternship, Transitional Year, 1998 - 1999
Northwestern University The Feinberg School of MedicineClass of 1997
Certifications & Licensure
MA State Medical License 2000 - 2027
American Board of Internal Medicine Endocrinology, Diabetes and Metabolism
Awards, Honors, & Recognition
- Father of the Year American Diabetes Association, 2019
- CMS Meaningful Use Stage 2 Certification OpTime Surgical 2014 Certified Module, Epic Systems Corporation, 2013-2014, 2016-2017
- CMS Meaningful Use Stage 1 Certification Longitudinal Medical Record, Partners Healthcare System, 2013-2014, 2016-2017
Clinical Trials
- Study to Understand the Genetics of the Acute Response to Metformin and Glipizide in Humans
- Study of Clinical Response to Acute Metformin By Leveraging Evaluations During a Mixed Meal Tolerance Test for Exploring Glycemia and GeneticS
- Effect of Lumacaftor-ivacaftor on Glucose Handling and Tolerance in Cystic Fibrosis Phe508del Start of enrollment: 2018 Jan 01
Publications & Presentations
PubMed
- 1 citationsBlood DNA methylation markers are associated with diabetic kidney disease progression in type 1 diabetes.Anna Syreeni, Emma H Dahlström, Laura J Smyth, Claire Hill, Stefan Mutter
Diabetologia. 2026-05-01 - Placental expression of GKN1 and diminished pancreatic beta cell function during pregnancy.Camille E Powe, Frederique White, Catherine Allard, Lydia Shook, Andrea Edlow
Diabetologia. 2026-04-01 - Diabetogenic processes for insulin resistance-linked hyperinsulinaemia are associated with colorectal cancer.Xuan Zhou, Magdalena Sevilla-Gonzalez, Amanda I Phipps, Miriam Udler, Sergi Castellví-Bel
Diabetologia. 2026-04-01
Journal Articles
- Genetic Ancestry Markers and Difference in A1c Between African-American and White in the Diabetes Prevention ProgramSteven Kahn, William C Knowler, Kieren J Mather, Jose C Florez, The Journal of Clinical Endocrinology and Metabolism
- Fine-Mapping Type 2 Diabetes Loci to Single-Variant Resolution Using High-Density Imputation and Islet-Specific Epigenome MapsChad M Brummett, Jose C Florez, Jerome I Rotter, Nature
- Genetic Determinants of Glycemic Traits and the Risk of Gestational Diabetes MellitusJose C Florez, Camille E Powe, Diabetes Care
Press Mentions
Joel Habener, Whose Research Led to Weight-Loss Drugs, Dies at 88January 9th, 2026
Remembering Dr. Joel HabenerDecember 30th, 2025
Saving More Lives Through Teamwork, New ApproachesJuly 23rd, 2025
Grant Support
- A functional genomics pipeline for genetic discovery in diabetic kidney diseaseBROAD INSTITUTE, INC.2022–2027
- Mentoring Investigators on the Clinical Translation of Cardiometabolic Genetic DiscoveriesMASSACHUSETTS GENERAL HOSPITAL2021–2026
- Pharmacogenetic discovery in the GRADE comparative effectiveness type 2 diabetes clinical trialMASSACHUSETTS GENERAL HOSPITAL2021–2025
- Study To Understand The Genetics Of The Acute Response To Metformin &GlipizideNational Institute Of Diabetes And Digestive And Kidney Diseases2010–2011
- Fine-Mapping And Characterization Of Metabolic Loci In The DPP Outcomes StudyNational Institute Of Diabetes And Digestive And Kidney Diseases2010–2011
Professional Memberships
- Member
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