JoseIgnacioMayordomoMD

PubMed

• 1 citations
  Safety and Efficacy of Tucatinib, Letrozole, and Palbociclib in Patients with Previously Treated HR+/HER2+ Breast Cancer.
  Elena Shagisultanova, William Gradishar, Pavani Chalasani, Andrew J Brenner, Alison Stopeck, Hannah Parris, Dexiang Gao, Jose Mayordomo, Peter Kabos, Virginia F Borges...> ;Clinical Cancer Research. 2023 Dec 15
• 3 citations
  Phase II trial of fulvestrant plus enzalutamide in ER+/HER2- advanced breast cancer.
  Anthony D Elias, Nicole S Spoelstra, Alyse W Staley, Sharon Sams, Lyndsey S Crump, Gregory A Vidal, Virginia F Borges, Peter Kabos, Jennifer R Diamond, Elena Shagisult...> ;NPJ Breast Cancer. 2023 May 20
• 32 citations
  Zanidatamab, a novel bispecific antibody, for the treatment of locally advanced or metastatic HER2-expressing or HER2-amplified cancers: a phase 1, dose-escalation and...
  Funda Meric-Bernstam, Muralidhar Beeram, Erika Hamilton, Do-Youn Oh, Diana L Hanna, Yoon-Koo Kang, Elena Elimova, Jorge Chaves, Rachel Goodwin, Jeeyun Lee, Lisle Nabel...> ;The Lancet. Oncology. 2022 Dec 1
• 1 citations
  Author Correction: GWAS of thyroid stimulating hormone highlights the pleiotropic effects and inverse association with thyroid cancer.
  Wei Zhou, Ben Brumpton, Omer Kabil, Julius Gudmundsson, Gudmar Thorleifsson, Josh Weinstock, Matthew Zawistowski, Jonas B Nielsen, Layal Chaker, Marco Medici, Alexande...> ;Nature Communications. 2021 Dec 16
• 64 citations
  GWAS of thyroid stimulating hormone highlights pleiotropic effects and inverse association with thyroid cancer.
  Wei Zhou, Ben Michael Brumpton, Omer Kabil, Julius Gudmundsson, Gudmar Thorleifsson, Josh Weinstock, Matthew Zawistowski, Jonas B. Nielsen, Layal Chaker, Marco Medici,...> ;Nature Communications. 2020 Aug 7
• 30 citations
  Assessing thyroid cancer risk using polygenic risk scores.
  Sandya Liyanarachchi, Julius Gudmundsson, Egil Ferkingstad, Huiling He, Jon G. Jonasson, Vinicius Tragante, Folkert W. Asselbergs, Li Xu, Lambertus A. Kiemeney, Romana...> ;Proceedings of the National Academy of Sciences of the United States of America. 2020 Mar 17
• 23 citations
  Lung Cancer Risk in Never-Smokers of European Descent is Associated With Genetic Variation in the 5p15.33 TERT-CLPTM1Ll Region
  Rayjean J. Hung, Margaret R. Spitz, Richard S. Houlston, Ann G. Schwartz, John K. Field, Jun Ying, Yafang Li, Younghun Han, Xuemei Ji, Wei V. Chen, Xifeng Wu, Ivan P. ...> ;Journal of Thoracic Oncology. 2019 Aug 1
• Triple-negative breast cancer in the elderly.
  Elena Shagisultanova, Jose I. Mayordomo, Anthony D. Elias> ;The Breast Journal. 2017 Nov 1
• 9 citations
  Correction: Corrigendum: Whole-genome sequencing identifies rare genotypes in COMP and CHADL associated with high risk of hip osteoarthritis
  Unnur Styrkarsdottir, Hannes Helgason, Asgeir Sigurdsson, Gudmundur L. Norddahl, Arna B Agustsdottir, Louise N. Reynard, Amanda Villalvilla, Gisli H. Halldorsson, Asla...> ;Nature Genetics. 2017 Aug 1
• Spinal Cord Injury due to Tumour or Metastasis in Aragón, Northeastern Spain (1991-2008): Incidence, Time Trends, and Neurological Function.
  Maayken van den Berg, Juan M. Castellote, Jose I. Mayordomo, Ignacio Mahillo-Fernández, Jesús de Pedro-Cuesta> ;Biomed Research International. 2017 Jul 25
• 17 citations
  Whole-genome sequencing identifies rare genotypes in COMP and CHADL associated with high risk of hip osteoarthritis.
  Unnur Styrkarsdottir, Hannes Helgason, Asgeir Sigurdsson, Gudmundur L Norddahl, Arna B Agustsdottir, Louise N Reynard, Amanda Villalvilla, Gisli H Halldorsson, Aslaug ...> ;Nature Genetics. 2017 May 1
• 97 citations
  A genome-wide association study yields five novel thyroid cancer risk loci.
  Julius Gudmundsson, Gudmar Thorleifsson, Jon K. Sigurdsson, Lilja Stefansdottir, Jon G. Jonasson, Sigurjon A. Gudjonsson, Daniel F. Gudbjartsson, Gisli Masson, Hrefna ...> ;Nature Communications. 2017 Feb 14
• 3 citations
  Breast Cancer Following Radiation for Hodgkin Lymphoma: Clinical Scenarios and Risk-Reducing Strategies
  Linda Overholser, Elena Shagisultanova, Rachel Rabinovitch, Nicole Kounalakis, Jennifer R. Diamond, Christina Finlayson, Christine M. Fisher, Peter Kabos, Anthony D. E...> ;Oncology. 2016 Dec 15
• 14 citations
  Pleiotropic Analysis of Lung Cancer and Blood Triglycerides
  Verena Zuber, Crystal N. Marconett, Jianxin Shi, Xing Hua, William Wheeler, Chenchen Yang, Lei Song, Anders M. Dale, Marina Laplana, Angela Risch, Aree Witoelar, Wesle...> ;Journal of the National Cancer Institute. 2016 Dec 1
• 31 citations
  Genetic Risk Can Be Decreased: Quitting Smoking Decreases and Delays Lung Cancer for Smokers With High and Low CHRNA5 Risk Genotypes — A Meta-Analysis
  Li-Shiun Chen, Timothy B. Baker, Rayjean J. Hung, Amy C. Horton, Robert Culverhouse, Sarah M. Hartz, Nancy L. Saccone, Iona Cheng, Bo Deng, Younghun Han, Helen M. Hans...> ;Ebiomedicine. 2016 Sep 1
• 20 citations
  A rare missense mutation in CHRNA4 associates with smoking behavior and its consequences
  Thorgeir E. Thorgeirsson, Stacy Steinberg, Gunnar W Reginsson, Gyda Bjornsdottir, Thorunn Rafnar, Ingileif Jonsdottir, Anna Helgadottir, Solveig Gretarsdottir, Hafdis ...> ;Molecular Psychiatry. 2016 Mar 8
• 20 citations
  Insertion of an SVA-E retrotransposon into the CASP8 gene is associated with protection against prostate cancer
  Simon N. Stacey, Birte Kehr, Julius Gudmundsson, Florian Zink, Aslaug Jonasdottir, Sigurjon A. Gudjonsson, Asgeir Sigurdsson, Bjarni V. Halldorsson, Bjarni A. Agnarsso...> ;Human Molecular Genetics. 2016 Mar 1
• 56 citations
  CHRNA5 Risk Variant Predicts Delayed Smoking Cessation and Earlier Lung Cancer Diagnosis—A Meta-Analysis
  Li-Shiun Chen, Rayjean J. Hung, Timothy S. Baker, Amy C. Horton, Rob Culverhouse, Nancy L. Saccone, Iona Cheng, Bo Deng, Younghun Han, Helen M. Hansen, Janet Horsman, ...> ;Journal of the National Cancer Institute. 2015 May 1
• 48 citations
  New basal cell carcinoma susceptibility loci
  Simon N. Stacey, Hannes Helgason, Sigurjon A. Gudjonsson, Gudmar Thorleifsson, Florian Zink, Asgeir Sigurdsson, Birte Kehr, Julius Gudmundsson, Patrick Sulem, Bardur S...> ;Nature Communications. 2015 Apr 9
• 38 citations
  Germline Sequence Variants in TGM3 and RGS22 Confer Risk of Basal Cell Carcinoma
  Simon N. Stacey, Patrick Sulem, Daniel F. Gudbjartsson, Aslaug Jonasdottir, Gudmar Thorleifsson, Sigurjon A. Gudjonsson, Gisli Masson, Julius Gudmundsson, Bardur Sigur...> ;Human Molecular Genetics. 2014 Jun 1
• 38 citations
  Genome-wide association study yields variants at 20p12.2 that associate with urinary bladder cancer
  Thorunn Rafnar, Patrick Sulem, Gudmar Thorleifsson, Sita H. Vermeulen, Hannes Helgason, Jona Saemundsdottir, Sigurjon A. Gudjonsson, Asgeir Sigurdsson, Simon N. Stacey...> ;Human Molecular Genetics. 2014 May 26
• 47 citations
  A common variant at 8q24.21 is associated with renal cell cancer.
  Julius Gudmundsson, Patrick Sulem, Daniel F. Gudbjartsson, Gisli Masson, Vigdis Petursdottir, Sverrir Hardarson, Sigurjon A. Gudjonsson, Hrefna Johannsdottir, Hafdis T...> ;Nature Communications. 2013 Nov 13
• 91 citations
  A variant in FTO shows association with melanoma risk not due to BMI
  Mark M. Iles, Matthew Law, Simon N. Stacey, Jiali Han, Shenying Fang, Ruth M. Pfeiffer, Mark Harland, Stuart MacGregor, John C. Taylor, Katja K.H. Aben, Lars A. Akslen...> ;Nature Genetics. 2013 Mar 3
• 133 citations
  A study based on whole-genome sequencing yields a rare variant at 8q24 associated with prostate cancer.
  Julius Gudmundsson, Patrick Sulem, Daniel F. Gudbjartsson, Gisli Masson, Bjarni A. Agnarsson, Kristrun R. Benediktsdottir, Asgeir Sigurdsson, Olafur T. Magnusson, Sigu...> ;Nature Genetics. 2012 Dec 1
• 9 citations
  Natural and Orthogonal Interaction Framework for Modeling Gene-Environment Interactions with Application to Lung Cancer
  Jianzhong Ma, Feifei Xiao, Momiao Xiong, Angeline S. Andrew, Hermann Brenner, Eric J. Duell, Aage Haugen, Clive J. Hoggart, Rayjean J. Hung, Philip Lazarus, Changlu Li...> ;Human Heredity. 2012 Aug 9
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Journal Articles

• Phase III Multicenter Clinical Trial of the sialyl-TN (STn)-keyhole limpet hemocyanin (KLH) Vaccine for Metastatic Breast Cancer  
  Ibrahim N, Miles D, Tres A, Roche H, Guillem V, Martin M, Perren T, Cameron D, Glaspy J, Dodwell D, Parker J, Mayordomo J, and the Theratope Study Group, Oncologist, 1/1/2011
• Spanish Society of Medical Oncology consensus for the use of haematopoietic colony-stimulating factors in cancer patients  
  Carrato Mena A, Paz-Ares Rodriguez L, Rodriguez Lescure A, Casas Fernandez de Tejerina AM, Diaz Rubio Garcia E, Perez Segura P, Constenla Figueiras M, Garcia Carbonero..., Clinical and Translational Oncology, 1/1/2009
• Retrospective cost analysis of management of febrile neutropenia in cancer patients in Spain  
  Mayordomo JI, Lopez A, Vinolas N, Castellanos J, Pernas S, Domingo Alonso J, Frau A, Layola M, Antonio Gasquet J, Sanchez J; ENIA Study Group, Curr Med Res Opin, 1/1/2009
• Phase II Randomized Study of Neoadjuvant Everolimus Plus Letrozole Compared With Placebo Plus Letrozole in Patients With Estrogen Receptor-Positive Breast Cancer  
  Baselga J, Semiglazov V, van Dam P, Manikhas A, Bellet M, Mayordomo J, Campone M, Kubista E, Greil R, Bianchi G, Steinseifer J, Molloy B, Tokaji E, Gardner H, Phillips..., Journal of Clinical Oncology, 1/1/2009
• Sequence variants at the TERT- CLPTM1L locus associate with multiple cancer types  
  Rafnar T, Sulem P, Stacey SN, Geller F, Gudmundsson J, Sigurdsson A, Jakobsdottir M, Helgadottir H, Thorlacius S, Aben KKH, Blondal T, Thorgeirsson T, Thorleifsson G, ..., Nat Genet, 1/1/2009
• Estimating the magnitude of trastuzumab effects within patient subgroups in the HERA trial  
  Untch M, Gelber RD, Jackisch C, Procter M, Baselga J, Bell R, Cameron D, Gianni L, Smith I, Leyland-Jones B, de Azambuja E, Wermuth P, Khasanov R, Feng-yi F, Hartmann ..., Ann Oncol, 1/1/2008
• Common Sequence Variants in the MRPS30 Locus on Chromosome 5p12 Confer Susceptibility to Estrogen Receptor Positive Breast cancer  
  Stacey SN, Manolescu A, Sulem P, Thorlacius S, Gudjonsson SA, Jonsson GF, Jakobsdottir M, Bergthorsson JT, Gudmundsson J, Sigurosson A, Aben KK, Strobbe LJ, Albers-Akk..., Nat Genet, 1/1/2008
• Neoadjuvant anastrozole alone or with gefitinib in early breast cancer: A phase II placebo controlled trial (223) with biological and clinical outcomes  
  Smith I, Walsh G, Skene A, Llombart A, Mayordomo JI, Detre S, Salter J, Clark E, Magill P Dowsett M, J Clin Oncol, 1/1/2007
• Common Variants on Chromosomes 2q35 and 16q12 Confer Susceptibility to Estrogen Receptor Positive Breast Cancer  
  Stacey SN, Manolescu A, Sulem P, Rafnar T, Gudmundsson J, Gudjonsson SA, Masson G, Jakobsdottir M, Thorlacius S, Helgason A, Aben KK, Henderson BE, Kolonel LN, Le Marc..., Nature Genetics, 1/1/2007
• Granulocyte colony-stimulating factor in the treatment of high-risk febrile neutropenia: A multicenter randomized trial  
  Garcia-Carbonero, R; Mayordomo JI; Tornamira, MV; Lopez-Brea, M; Rueda, A; Guillem, V; Arcediano, A; Yubero, A; Ribera, F; Gomez, C; Tres, A; Perez-Gracia, JL; Lumbrer..., Journal of the National Cancer Institute, 1/1/2001
• Peptide-pulsed dendritic cells induce antigen-specific, CTL-mediated protective tumor immunity  
  Celluzzi, CM; Mayordomo JI; Storkus, WJ; Lotze, MT; Falo, LD, Journal of Experimental Medicine, 1/1/1996
• Therapy of murine tumors with p53 wild-type and mutant sequence peptide-based vaccines  
  Mayordomo JI; Loftus, DJ; Sakamoto, H; DeCesare, CM; Appasamy, PM; Lotze, MT; Storkus, WJ; Appella, E; DeLeo, AB, Journal of Experimental Medicine, 1/1/1996
• Therapy of murine tumors with tumor peptide-pulsed dendritic cells: Dependence on T cells, B7 costimulation, and T helper cell 1-associated cytokines  
  Zitvogel, L; Mayordomo JI; Tjandrawan, T; DeLeo, AB; Clarke, MR; Lotze, MT; Storkus, WJ, Journal of Experimental Medicine, 1/1/1996
• Improving treatment of chemotherapy-induced neutropenic fever by administration of colony-stimulating factors  
  Mayordomo JI; Rivera F; Diaz-Puente MT; Lianes P; Colomer R; Lopez-Brea M; Lopez E; Paz-Ares L; Hitt R; Garcia Ribas I; Cubedo R; Alonso S; Cortes-Funes H, Journal of the National Cancer Institute, 1/1/1995
• Bone-marrow-derived dendritic cells pulsed with synthetic tumor peptides elicit protective and therapeutic antitumor immunity  
  Mayordomo JI; Zorina T; Storkus WJ; Zitvogel L; Celluzzi C; Falo LD; Melief CJ; Ilstad ST; Kast WM; De Leo AB; Lotze MT, Nature Medicine, 1/1/1995
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