JosephBelanoffMD

PubMed

• 1 citations
  Biochemical and Radiological Changes in Liver Steatosis Following Mifepristone Treatment in Patients With Hypercortisolism
  John C. Parker, Andreas G. Moraitis, Joseph K. Belanoff> ;AACE Clinical Case Reports. 2021 Jul 12
• 13 citations
  Insights into the Therapeutic Potential of Glucocorticoid Receptor Modulators for Neurodegenerative Diseases
  Alejandro F. De Nicola, Maria Meyer, Rachida Guennoun, Michael Schumacher, Hazel Hunt, Joseph K. Belanoff, E. Ronald de Kloet, Maria Claudia Gonzalez Deniselle> ;International Journal of Molecular Sciences. 2020 Mar 20
• 14 citations
  Long-term effects of the glucocorticoid receptor modulator CORT113176 in murine motoneuron degeneration.
  Maria Meyer, Maria Sol Kruse, Laura Garay, Analia Lima, Paulina Roig, Hazel Hunt, Joseph K. Belanoff, E. Ronald de Kloet, Maria Claudia Gonzalez Deniselle, Alejandro F...> ;Brain Research. 2020 Jan 15
• 16 citations
  Glucocorticoid receptors signaling impairment potentiates amyloid-β oligomers-induced pathology in an acute model of Alzheimer's disease.
  Geoffrey Canet, Fanny Pineau, Charleine Zussy, Célia Hernandez, Hazel Hunt, Nathalie Chevallier, Véronique Perrier, Joan Torrent, Joseph K. Belanoff, Onno C. Meijer, C...> ;FASEB Journal. 2020 Jan 1
• 28 citations
  Resetting the Stress System with a Mifepristone Challenge.
  Sergiu Dalm, Adriaan M. Karssen, Onno C. Meijer, Joseph K. Belanoff, E. Ronald de Kloet> ;Cellular and Molecular Neurobiology. 2019 May 1
• 40 citations
  Selective Glucocorticoid Receptor Modulation Prevents and Reverses Nonalcoholic Fatty Liver Disease in Male Mice
  Lisa L. Koorneef, José K. van den Heuvel, Jan Kroon, Mariëtte R. Boon, Peter A C 't Hoen, Kristina Hettne, Nienke M van de Velde, Kelsey B Kolenbrander, Trea C M Stree...> ;Endocrinology. 2018 Dec 1
• 15 citations
  The Selective Glucocorticoid Receptor Modulator Cort 113176 Reduces Neurodegeneration and Neuroinflammation in Wobbler Mice Spinal Cord.
  Maria Meyer, Agustina Lara, Hazel Hunt, Joseph K. Belanoff, E. Ronald de Kloet, Maria Claudia Gonzalez Deniselle, Alejandro F. De Nicola> ;Neuroscience. 2018 Aug 1
• 33 citations
  Assessment of Safety, Tolerability, Pharmacokinetics, and Pharmacological Effect of Orally Administered CORT125134: An Adaptive, Double-Blind, Randomized, Placebo-Cont...
  Hazel Hunt, Kirsteen Donaldson, Mark Strem, Vanessa Zann, Pui Leung, Suzanne Sweet, Alyson Connor, Dan Combs, Joseph K. Belanoff> ;Clinical Pharmacology in Drug Development. 2018 May 1
• 49 citations
  Combined Analysis of Mifepristone for Psychotic Depression: Plasma Levels Associated With Clinical Response.
  Thaddeus Block, Harvey Kushner, Ned H. Kalin, Craig Nelson, Joseph K. Belanoff, Alan F. Schatzberg> ;Biological Psychiatry. 2018 Jul 1
• 38 citations
  Identification of the Clinical Candidate (R)-(1-(4-Fluorophenyl)-6-((1-methyl-1H-pyrazol-4-yl)sulfonyl)-4,4a,5,6,7,8-hexahydro-1H-pyrazolo[3,4-g]isoquinolin-4a-yl)(4-(...
  Hazel Hunt, Joseph K. Belanoff, Iain Walters, Benoit Gourdet, Jennifer Thomas, Naomi Barton, John Unitt, Timothy Phillips, Denise Swift, Emily Eaton> ;Journal of Medicinal Chemistry. 2017 Apr 17
• 50 citations
  The role of glucocorticoid receptors in metabolic syndrome and psychiatric illness.
  Andreas G. Moraitis, Thaddeus Block, Dat Nguyen, Joseph K. Belanoff> ;The Journal of Steroid Biochemistry and Molecular Biology. 2017 Jan 1
• 47 citations
  New selective glucocorticoid receptor modulators reverse amyloid-β peptide-induced hippocampus toxicity.
  Fanny Pineau, Geoffrey Canet, Catherine Desrumaux, Hazel Hunt, Nathalie Chevallier, Matthias Ollivier, Joseph K. Belanoff, Laurent Givalois> ;Neurobiology of Aging. 2016 Sep 1
• 9 citations
  Glucocorticoid antagonism limits adiposity rebound and glucose intolerance in young male rats following the cessation of daily exercise and caloric restriction.
  Trevor Teich, Emily C. Dunford, Deanna P. Porras, Jacklyn A. Pivovarov, Jacqueline L. Beaudry, Hazel Hunt, Joseph K. Belanoff, Michael C. Riddell> ;American Journal of Physiology. Endocrinology and Metabolism. 2016 May 3
• 27 citations
  Identification of a selective glucocorticoid receptor modulator that prevents both diet-induced obesity and inflammation.
  José K. van den Heuvel, Mariëtte R. Boon, Ingmar van Hengel, Emma Peschier-van der Put, Lianne van Beek, Vanessa van Harmelen, Ko Willems van Dijk, Alberto M. Pereira,...> ;British Journal of Pharmacology. 2016 Jun 1
• 17 citations
  1H-Pyrazolo[3,4-g]hexahydro-isoquinolines as potent GR antagonists with reduced hERG inhibition and an improved pharmacokinetic profile.
  Hazel Hunt, Joseph K. Belanoff, Emily Golding, Benoit Gourdet, Timothy Phillips, Denise Swift, Jennifer Thomas, John Unitt, Iain Walters> ;Bioorganic & Medicinal Chemistry Letters. 2015 Dec 15
• 40 citations
  A Mixed Glucocorticoid/Mineralocorticoid Selective Modulator With Dominant Antagonism in the Male Rat Brain
  Erika Atucha, Ioannis Zalachoras, José K. van den Heuvel, Lisa T. C. M. van Weert, Diana Melchers, Isabel M. Mol, Joseph K. Belanoff, René Houtman, Hazel Hunt, Benno R...> ;Endocrinology. 2015 Aug 25
• 147 citations
  Glucocorticoid receptor antagonism decreases alcohol seeking in alcohol-dependent individuals
  Leandro F. Vendruscolo, David Estey, Vivian Goodell, Lauren G. Macshane, Marian L. Logrip, Joel E. Schlosburg, M. Adrienne McGinn, Eva R. Zamora-Martinez, Joseph K. Be...> ;The Journal of Clinical Investigation. 2015 Aug 3
• 25 citations
  Effects of Selective and Non-Selective Glucocorticoid Receptor II Antagonists on Rapid-Onset Diabetes in Young Rats
  Jacqueline L. Beaudry, Emily C. Dunford, Trevor Teich, Dessi P. Zaharieva, Hazel Hunt, Joseph K. Belanoff, Michael C. Riddell> ;Plos One. 2014 Mar 18
• 86 citations
  Differential targeting of brain stress circuits with a selective glucocorticoid receptor modulator.
  Ioannis Zalachoras, René Houtman, Erika Atucha, Rene Devos, A. M. I. Tijssen, Pu Hu, Peter Lockey, Nicole A. Datson, Joseph K. Belanoff, Paul J. Lucassen, Marian Joëls...> ;Proceedings of the National Academy of Sciences of the United States of America. 2013 May 7
• 16 citations
  Administration of a selective glucocorticoid antagonist attenuates electroconvulsive shock-induced retrograde amnesia
  Chittaranjan Andrade, Shahid Ahmad Shaikh, Lakshmy Narayan, Christine Blasey, Joseph K. Belanoff> ;Journal of Neural Transmission. 2012 Mar 1
• 50 citations
  Efficacy and safety of mifepristone for the treatment of psychotic depression.
  Christine Blasey, Thaddeus Block, Joseph K. Belanoff, Robert Roe> ;Journal of Clinical Psychopharmacology. 2011 Aug 1
• 21 citations
  Selective Glucocorticoid Receptor (GR-II) Antagonist Reduces Body Weight Gain in Mice.
  Tomoko Asagami, Joseph K. Belanoff, Junya Azuma, Christine Blasey, Robin D. Clark, Philip S. Tsao> ;Journal of Nutrition and Metabolism. 2011 Jul 28
• 6 citations
  Selective glucocorticoid receptor (type II) antagonists prevent weight gain caused by olanzapine in rats
  Joseph K. Belanoff, Christine Blasey, Robin D. Clark, Robert Roe> ;European Journal of Pharmacology. 2011 Mar 25
• 36 citations
  Mifepristone Reduces Weight Gain and Improves Metabolic Abnormalities Associated With Risperidone Treatment in Normal Men
  Coleman Gross, Christine Blasey, Robert Roe, Joseph K. Belanoff> ;Obesity. 2010 Dec 1
• 35 citations
  Mifepristone treatment of olanzapine-induced weight gain in healthy men
  Coleman Gross, Christine Blasey, Robert Roe, Kate Allen, Thaddeus Block, Joseph K. Belanoff> ;Advances in Therapy. 2009 Nov 4
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