JosephWangFransesMDPhD

Oncology • Chicago, IL

Gastrointestinal Cancer

Assistant Professor (attending oncologist, physician-scientist laboratory PI)

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Office
5758 S Maryland Ave
Chicago, IL 60637
Phone+1 773-702-6149
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Education & Training

Brigham and Women's Hospital/Massachusetts General Hospital/Dana-Farber Cancer InstituteFellowship, Hematology and Medical Oncology, 2019
Massachusetts General HospitalResidency, Internal Medicine, 2013 - 2015
Harvard Medical SchoolClass of 2013

Certifications & Licensure

IL State Medical License 2023 - 2026
MA State Medical License 2013 - 2025
IN State Medical License 2023 - 2025
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Medical Oncology

Publications & Presentations

PubMed

Dysregulated Repeat Element Viral-like Immune Response in Hepatocellular Carcinoma.
Avril K Coley, Chenyue Lu, Amaya Pankaj, Matthew J Emmett, Evan R Lang, Yuhui Song, Katherine H Xu, Nova Xu, Bidish K Patel, Abhijit Chougule, Linda T Nieman, Martin J...> ;Biorxiv. 2023 Dec 5
Patient-Reported Outcomes, Tumor Markers, and Survival Outcomes in Advanced GI Cancer.
Joy X Jarnagin, Anurag Saraf, Islam Baiev, Gary Chi, Emily E van Seventer, Amirkasra Mojtahed, Jill N Allen, Jeffrey W Clark, Lawrence Blaszkowsky, Bruce J Giantonio, ...> ;JAMA Network Open. 2023 Nov 1
5 citations
Profile and Predictors of Blood Tumor Mutational Burden in Advanced Hepatocellular Carcinoma.
Joseph W Franses, Mir Lim, Adam M Burgoyne, Kabir Mody, Jochen Lennerz, Jeremy Chang, Robin Imperial, Stacey N Dybel, Thi M Dinh, Jude Masannat, Caroline M Weipert, Da...> ;The Oncologist. 2022 Nov 3
5 citations
Neoadjuvant Approaches in Hepatocellular Carcinoma: There's No Time Like the Present.
Joseph W Franses, Andrew X Zhu> ;Clinical Cancer Research. 2022 Jul 1
PLSec: A novel, liquid biomarker for HCC risk.
Joseph W Franses, Irun Bhan, Andrew X Zhu> ;Med. 2021 Jul 9
4 citations
Spontaneous Immune-Mediated Regression of Hepatocellular Carcinoma With High Tumor Mutational Burden.
Joseph W. Franses, Irun Bhan, Amaya Pankaj, David T. Ting, Vikram Deshpande, Kenneth K. Tanabe> ;JCO Precision Oncology. 2021 Jun 17
7 citations
Care Patterns and Overall Survival in Patients With Early-Onset Metastatic Colorectal Cancer.
Katie Kanter, Madeleine Fish, Gianluca Mauri, Nora Horick, Jill N. Allen, Lawrence S. Blaszkowsky, Jeffrey W. Clark, David P. Ryan, Ryan D. Nipp, Bruce J. Giantonio, L...> ;JCO Oncology Practice. 2021 May 27
50 citations
Pancreatic circulating tumor cell profiling identifies LIN28B as a metastasis driver and drug target.
Joseph W. Franses, Julia Philipp, Pavlos Missios, Irun Bhan, A. W. K. Liu, Chittampalli Yashaswini, Eric Tai, Huili Zhu, Matteo Ligorio, Benjamin Nicholson, Elizabeth ...> ;Nature Communications. 2020 Jul 3
2 citations
Nivolumab with gemcitabine plus cisplatin for biliary cancers: as easy as ABC?
Joseph W. Franses, Theodore S. Hong, Andrew X. Zhu> ;The Lancet. Gastroenterology & Hepatology. 2019 Aug 1
334 citations
Stromal Microenvironment Shapes the Intratumoral Architecture of Pancreatic Cancer
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1 citations
Has PD-1 MET Its Match in Hepatocellular Carcinoma?
Joseph W. Franses, Andrew X. Zhu> ;Gastroenterology. 2019 May 1
25 citations
Detection and Analysis of Circulating Epithelial Cells in Liquid Biopsies From Patients With Liver Disease.
Irun Bhan, Mosesso Kelly, Lipika Goyal, Mark Kalinich, Joseph W. Franses, Melissa Choz, Rahmi Oklu, Mehmet Toner, Shyamala Maheswaran, Daniel A. Haber, Andrew X. Zhu, ...> ;Gastroenterology. 2018 Sep 13
2 citations
Regarding "Improved Detection of Circulating Epithelial Cells in Patients with Intraductal Papillary Mucinous Neoplasms".
Go J. Yoshida> ;The Oncologist. 2018 Oct 1
15 citations
Improved Detection of Circulating Epithelial Cells in Patients with Intraductal Papillary Mucinous Neoplasms.
Joseph W Franses, Omer Basar, Abdurrahman Kadayifci, Osman Yuksel, Melissa Choz, Anupriya S Kulkarni, Eric Tai, Kevin D Vo, Kshitu S Arora, Niyati Desai, Joseph A Lica...> ;The Oncologist. 2018 Oct 1
11 citations
Improved Detection of Circulating Epithelial Cells in Patients with Intraductal Papillary Mucinous Neoplasms.
Joseph W Franses, Omer Basar, Abdurrahman Kadayifci, Osman Yuksel, Melissa Choz, Anupriya S Kulkarni, Eric Tai, Kevin D Vo, Kshitij S Arora, Niyati Desai, Joseph A Lic...> ;The Oncologist. 2018 Jan 1
4 citations
Matrix-Embedded Endothelial Cells Attain a Progenitor-Like Phenotype.
Eytan Abraham, Or Gadish, Joseph W. Franses, Vipul C. Chitalia, Natalie Artzi, Elazer R. Edelman> ;Advanced Biosystems. 2017 Jul 20
81 citations
Dysfunctional endothelial cells directly stimulate cancer inflammation and metastasis.
Joseph W. Franses, Natalia C. Drosu, William J. Gibson, Vipul C. Chitalia, Elazer R. Edelman> ;International Journal of Cancer. 2013 Sep 15
45 citations
Mechanisms of Tissue Uptake and Retention in Zotarolimus-Coated Balloon Therapy
Vijaya B. Kolachalama, Stephen D. Pacetti, Joseph W. Franses, John Stankus, Hugh Q. Zhao, Tarek Shazly, Alexander Nikanorov, Lewis B. Schwartz, Abraham R. Tzafriri, El...> ;Circulation. 2013 May 21
17 citations
The evolution of endothelial regulatory paradigms in cancer biology and vascular repair.
Joseph W. Franses, Elazer R. Edelman> ;Cancer Research. 2011 Dec 15
Matrix-embedded endothelial cells are protected from the uremic milieu.
Chitalia, V.C., Murikipudi, S., Indolfi, L., Rabadi, L., Valdez, R., Franses, J.W., Edelman, E.R.> ;Nephrol Dial Transplant. 2011 Dec
Stromal endothelial cells directly influence cancer progression.
Franses, J.W., Baker, A.B., Chitalia, V.C., Edelman, E.R.> ;Sci Transl Med. 2011 Jan 19
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Hospital Affiliations

University of Chicago Medical CenterChicago, Illinois