JosephGeradtsMD

PubMed

• XIAP overexpressing inflammatory breast cancer patients have high infiltration of immunosuppressive subsets and increased TNFR1 signaling targetable with Birinapant.
  Van Berckelaer, C., Van Laere, S., Lee, S., Dirix, L., Kockx, M., Bertucci, F., Van Dam, P., Devi, G., Morse, M., Geradts, J.> ;Translational Oncology. 2024 May 1
• Androgen deprivation induces double-null prostate cancer via aberrant nuclear export and ribosomal biogenesis through HGF and Wnt activation.
  Won Kyung Kim, Alyssa J Buckley, Dong-Hoon Lee, Alex Hiroto, Christian H Nenninger, Adam W Olson, Jinhui Wang, Zhuo Li, Rajeev Vikram, Yao Mawulikplimi Adzavon, Tak-Yu...> ;Nature Communications. 2024 Feb 9
• 1 citations
  Predicting early breast cancer recurrence from histopathological images in the Carolina Breast Cancer Study.
  Yifeng Shi, Linnea T Olsson, Katherine A Hoadley, Benjamin C Calhoun, J S Marron, Joseph Geradts, Marc Niethammer, Melissa A Troester> ;NPJ Breast Cancer. 2023 Nov 11
• 1 citations
  Growth Dynamics of Ductal Carcinoma in Situ Recapitulate Normal Breast Development.
  Marc D Ryser, Matthew A Greenwald, Inmaculada C Sorribes, Lorraine M King, Allison Hall, Joseph Geradts, Donald L Weaver, Diego Mallo, Shannon Holloway, Daniel Monyak,...> ;Biorxiv. 2023 Oct 2
• Differential distribution of actual and surrogate oncotype DX recurrence scores in breast cancer patients by age, menopausal status, race, and body mass index.
  Anas Mohamed, Linnea T Olsson, Joseph Geradts> ;Breast Cancer Research and Treatment. 2023 Oct 1
• 1 citations
  Reproducibility and intratumoral heterogeneity of the PAM50 breast cancer assay.
  Amber N Hurson, Alina M Hamilton, Linnea T Olsson, Erin L Kirk, Mark E Sherman, Benjamin C Calhoun, Joseph Geradts, Melissa A Troester> ;Breast Cancer Research and Treatment. 2023 May 1
• 3 citations
  Stromal androgen signaling acts as tumor niches to drive prostatic basal epithelial progenitor-initiated oncogenesis.
  Alex Hiroto, Won Kyung Kim, Ariana Pineda, Yongfeng He, Dong-Hoon Lee, Vien Le, Adam W Olson, Joseph Aldahl, Christian H Nenninger, Alyssa J Buckley, Guang-Qian Xiao, ...> ;Nature Communications. 2022 Nov 2
• 9 citations
  Gene expression signatures of individual ductal carcinoma in situ lesions identify processes and biomarkers associated with progression towards invasive ductal carcinoma.
  Clare A Rebbeck, Jian Xian, Susanne Bornelöv, Joseph Geradts, Amy Hobeika, Heather Geiger, Jose Franco Alvarez, Elena Rozhkova, Ashley Nicholls, Nicolas Robine, Herber...> ;Nature Communications. 2022 Jun 13
• 1 citations
  Pathobiologic Stratification of Oncotype DX Recurrence Scores and Comparative Validation of 3 Surrogate Models.
  Anas Mohamed, Aisha Kousar, Jan Wong, Nasreen Vohra, Mahvish Muzaffar, Joseph Geradts> ;Archives of Pathology & Laboratory Medicine. 2022 Oct 1
• 1 citations
  Correction: Upregulation of VEGF-A and CD24 gene expression by the tGLI1 transcription factor contributes to the aggressive behavior of breast cancer cells.
  X Cao, J Geradts, M W Dewhirst, H-W Lo> ;Oncogene. 2022 Feb 1
• 2 citations
  JOINT AND INDIVIDUAL ANALYSIS OF BREAST CANCER HISTOLOGIC IMAGES AND GENOMIC COVARIATES.
  Iain Carmichael, Benjamin C Calhoun, Katherine A Hoadley, Melissa A Troester, Joseph Geradts, Heather D Couture, Linnea Olsson, Charles M Perou, Marc Niethammer, Jan H...> ;The Annals of Applied Statistics. 2021 Dec 1
• 3 citations
  Race-Related Differences in the Clinical Presentation and Histopathologic Features of Phyllodes Tumor.
  Helen M. Johnson, Anas Mohamed, Muhammad M. Hassan, Joseph Geradts, Nasreen A. Vohra, Jan H. Wong> ;The American Surgeon. 2021 Jun 30
• 17 citations
  Expression of X-Linked Inhibitor of Apoptosis Protein (XIAP) in Breast Cancer Is Associated with Shorter Survival and Resistance to Chemotherapy.
  Gayathri R. Devi, Pascal Finetti, Michael A. Morse, Seayoung Lee, Alexandre de Nonneville, Steven Van Laere, Jesse D. Troy, Joseph Geradts, Shannon J. McCall, François...> ;Cancers. 2021 Jun 4
• 10 citations
  Outcomes of Hormone-Receptor Positive, HER2-Negative Breast Cancers by Race and Tumor Biological Features.
  Halei C. Benefield, Katherine E. Reeder-Hayes, Hazel B. Nichols, Benjamin C. Calhoun, Michael I. Love, Erin L. Kirk, Joseph Geradts, Katherine A. Hoadley, Stephen R. C...> ;JNCI Cancer Spectrum. 2021 Jan 5
• 3 citations
  Spatiotemporal strategies to identify aggressive biology in precancerous breast biopsies
  David E. Frankhauser, Tijana Jovanovic-Talisman, Lily L. Lai, Lisa D. Yee, Lihong V. Wang, Ashish Mahabal, Joseph Geradts, Russell C. Rockne, Jerneja Tomsic, Veronica ...> ;Wires Mechanisms of Disease. 2021 Mar 1
• 14 citations
  Borderline Estrogen Receptor-Positive Breast Cancers in Black and White Women
  Halei C. Benefield, Emma H. Allott, Katherine E. Reeder-Hayes, Charles M. Perou, Lisa A. Carey, Joseph Geradts, Xuezheng Sun, Benjamin C. Calhoun, Melissa A. Troester> ;Journal of the National Cancer Institute. 2020 Jul 1
• 1 citations
  Quantitative assessment of distant recurrence risk in early stage breast cancer using a nonlinear combination of pathological, clinical and imaging variables.
  Brandon S. Nichols, Erika Chelales, Roujia Wang, Amanda Schulman, Jennifer Gallagher, Rachel A. Greenup, Joseph Geradts, Josephine Harter, Paul K. Marcom, Lee G. Wilke...> ;Journal of Biophotonics. 2020 Jun 23
• 87 citations
  Reversion and non-reversion mechanisms of resistance to PARP inhibitor or platinum chemotherapy in BRCA1/2-mutant metastatic breast cancer.
  Adrienne G. Waks, Ofir Cohen, Bose Kochupurakkal, Dae Hyun Kim, Connor E. Dunn, Jorge Buendia Buendia, Seth A. Wander, Karla Helvie, Max Lloyd, Lori Marini, Melissa E....> ;Annals of Oncology. 2020 May 1
• 7 citations
  Androgen receptor with short polyglutamine tract preferably enhances Wnt/β-catenin-mediated prostatic tumorigenesis.
  Yongfeng He, Jiaqi Mi, Adam Olson, Joseph Aldahl, Erika Hooker, Eun-Jeong Yu, Vien Le, Dong-Hoon Lee, Won Kyung Kim, Diane M. Robins, Joseph Geradts, Zijie Sun> ;Oncogene. 2020 Feb 24
• 15 citations
  Loss of androgen signaling in mesenchymal sonic hedgehog responsive cells diminishes prostate development, growth, and regeneration.
  Vien Le, Yongfeng He, Joseph Aldahl, Erika Hooker, Eun-Jeong Yu, Adam Olson, Won Kyung Kim, Dong-Hoon Lee, Monica T. Y. Wong, Ruoyu Sheng, Jiaqi Mi, Joseph Geradts, Ge...> ;Plos Genetics. 2020 Jan 13
• 6 citations
  Aberrant activation of hepatocyte growth factor/MET signaling promotes β-catenin–mediated prostatic tumorigenesis
  Joseph Aldahl, Jiaqi Mi, Ariana Pineda, Won Kyung Kim, Adam Olson, Erika Hooker, Yongfeng He, Eun-Jeong Yu, Vien Le, Dong-Hoon Lee, Joseph Geradts, Zijie Sun> ;The Journal of Biological Chemistry. 2020 Jan 10
• 5 citations
  DNA methylation markers predict recurrence-free interval in triple-negative breast cancer.
  Mary Jo Fackler, Soonweng Cho, Leslie Cope, Edward Gabrielson, Kala Visvanathan, Kathleen Wilsbach, Charles F Lynch, Jeffrey Marks, Joseph Geradts, Meredith M Regan, G...> ;NPJ Breast Cancer. 2020 Jan 1
• 7 citations
  Bimodal age distribution at diagnosis in breast cancer persists across molecular and genomic classifications.
  Emma H. Allott, Yue Shan, Mengjie Chen, Xuezheng Sun, Susana García-Recio, Erin L. Kirk, Andrew F. Olshan, Joseph Geradts, H. Shelton Earp, Lisa A. Carey, Charles M. P...> ;Breast Cancer Research and Treatment. 2020 Jan 1
• 19 citations
  The comprehensive role of E-cadherin in maintaining prostatic epithelial integrity during oncogenic transformation and tumor progression.
  Adam Olson, Vien Le, Joseph Aldahl, Eun Jeong Yu, Erika Hooker, Yongfeng He, Dong Hong Lee, Won Kyung Kim, Robert D. Cardiff, Joseph Geradts, Zijie Sun> ;Plos Genetics. 2019 Oct 28
• 6 citations
  Loss of the tumor suppressor, Tp53, enhances the androgen receptor-mediated oncogenic transformation and tumor development in the mouse prostate.
  Yongfeng He, Daniel T. Johnson, Julie S Yang, Huiqing Wu, Sungyong You, Junhee Yoon, Dong-Hoon Lee, Won Kyung Kim, Joseph Aldahl, Vien Le, Erika Hooker, Eun-Jeong Yu, ...> ;Oncogene. 2019 Jul 29
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