JosephBLillegardMD

Pediatric (General) Surgery • Minneapolis, MN

Physician

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Office
2530 Chicago Ave
Minneapolis, MN 55404
Phone+1 612-813-8606

Fax+1 612-813-8005
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Summary

Dr. Joseph Lillegard, MD is a Pediatric Surgeon in Minneapolis, Minnesota. He is currently licensed to practice medicine in Minnesota, Tennessee, and New Hampshire. He is affiliated with Regions Hospital.

Education & Training

Children's Hospital of PhiladelphiaFellowship, Pediatric Surgery, 2013 - 2015
Mayo Clinic College of Medicine and Science (Rochester)Residency, Surgery, 2006 - 2013
University of Nevada, Reno School of MedicineClass of 2006

Certifications & Licensure

TN State Medical License 2023 - 2024
MN State Medical License 2007 - 2024
NH State Medical License 2017 - 2021
PA State Medical License 2013 - 2016
American Board of Surgery Surgery
American Board of Surgery Pediatric Surgery

Clinical Trials

Gastroschisis Outcomes of Delivery (GOOD) Study Start of enrollment: 2018 Feb 23
Recruiting
Phase 3

Publications & Presentations

PubMed

Activation of homology-directed DNA repair plays key role in CRISPR-mediated genome correction.
Gourish Mondal, Caitlin J VanLith, Clara T Nicolas, Whitney S Thompson, William S Cao, Lori Hillin, Benjamin J Haugo, Daniel R O' Brien, Jean-Pierre Kocher, Robert A K...> ;Gene Therapy. 2023 Apr 1
2 citations
In vivo lentiviral vector gene therapy to cure hereditary tyrosinemia type 1 and prevent development of precancerous and cancerous lesions.
Clara T Nicolas, Caitlin J VanLith, Raymond D Hickey, Zeji Du, Lori G Hillin, Rebekah M Guthman, William J Cao, Benjamin Haugo, Annika Lillegard, Diya Roy, Aditya Bhag...> ;Nature Communications. 2022 Aug 25
2 citations
Parental request for non-resuscitation in fetal myelomeningocele repair: an analysis of the novel ethical tensions in fetal intervention.
Ian D Wolfe, Joseph B Lillegard, Brian S Carter> ;Journal of Perinatology. 2022 Jul 1
4 citations
Understanding the Care Journey and Needs of Advanced Fetal Care Center Patients.
Stephanie A Eyerly-Webb, Heidi Ylvisaker, Megan Beh, Foong-Yen Lim, Kenneth Liechty, Pamela Velasco, Eric Dion, Saul Snowise, Joseph B Lillegard, Brad Feltis> ;The Permanente Journal. 2022 Jun 29
Placental Location in Maternal-Fetal Surgery for Myelomeningocele.
Joseph B Lillegard, Stephanie A Eyerly-Webb, David A Watson, Mert Ozan Bahtiyar, Kelly A Bennett, Stephen P Emery, Allan J Fisher, Ruth B Goldstein, William H Goodnigh...> ;Fetal Diagnosis and Therapy. 2022 Jan 1
1 citations
Limited Expansion of Human Hepatocytes in FAH/RAG2-Deficient Swine.
Erek Nelson, Ellen L. Larson, Dong Jin Joo, Shennen A. Mao, Jaime Glorioso, Anan Abu Rmilah, Wei Zhou, Yao Jia, Taofic Mounajjed, Min Shi, Melanie C. Bois, Adam J. Woo...> ;Tissue Engineering. Part A. 2021 Oct 7
1 citations
Successful Treatment of Placental Chorangiomas by Ultrasound-Guided Percutaneous in utero Microcoil Embolization.
James L. Fisher, Lisa Howley, Joseph B. Lillegard, Vinit Amin, Bjorn I. Engstrom, Saul Snowise> ;Fetal Diagnosis and Therapy. 2021 Jan 1
6 citations
Use of an adeno-associated virus serotype Anc80 to provide durable cure of phenylketonuria in a mouse model.
Robert A. Kaiser, Nicholas D. Weber, Laia Trigueros-Motos, Kari L. Allen, Michael Martinez, William Cao, Caitlin J. VanLith, Lori G Hillin, Anne Douar, Gloria González...> ;Journal of Inherited Metabolic Disease. 2021 Apr 25
4 citations
Development of a porcine model of phenylketonuria with a humanized R408W mutation for gene editing
Robert A. Kaiser, Daniel F. Carlson, Kari L. Allen, Dennis A. Webster, Caitlin J. VanLith, Clara T. Nicolas, Lori G Hillin, Yue Yu, Catherine W. Kaiser, William R. Wah...> ;Plos One. 2021 Jan 25
2 citations
Fetal Non-Ovarian Abdominopelvic Cystic Lesions: A Single-Center Report.
Stephanie A Eyerly-Webb, Shilvi Joshi, Eric Dion, Saul Snowise, Joseph B. Lillegard, Brad A. Feltis> ;Fetal Diagnosis and Therapy. 2020 Oct 13
7 citations
Ex Vivo Cell Therapy by Ectopic Hepatocyte Transplantation Treats the Porcine Tyrosinemia Model of Acute Liver Failure.
Clara T. Nicolas, Robert A. Kaiser, Raymond D. Hickey, Kari L. Allen, Zeji Du, Caitlin J. VanLith, Rebekah M. Guthman, Bruce Amiot, Lukkana Suksanpaisan, Bing Han, Mar...> ;Molecular Therapy. Methods & Clinical Development. 2020 Sep 11
8 citations
The future of gene-targeted therapy for hereditary tyrosinemia type 1 as a lead indication among the inborn errors of metabolism.
Whitney S. Thompson, Gourish Mondal, Caitlin J. VanLith, Robert A. Kaiser, Joseph B. Lillegard> ;Expert Opinion on Orphan Drugs. 2020 Jul 21
5 citations
Dynamic discriminant model for predicting respiratory distress at birth based on mass volume ratio in fetuses with congenital lung malformation.
Stephanie A Eyerly-Webb, C. T. Nicolas, D. Watson, Eric Dion, Ruchi Amin, Amy J. Wagner, A. Lampland, Ellen M. Bendel-Stenzel, C. A. Macardle, S. M. Kunisaki, A. Jorge...> ;Ultrasound in Obstetrics & Gynecology. 2019 Dec 1
14 citations
Autologous Gene and Cell Therapy Provides Safe and Long-Term Curative Therapy in A Large Pig Model of Hereditary Tyrosinemia Type 1.
Raymond D. Hickey, Clara T. Nicolas, Kari L. Allen, Shennen A. Mao, Faysal Elgilani, Jaime Glorioso, Bruce Amiot, Caitlin J. VanLith, Rebekah M. Guthman, Zeji Du, Harv...> ;Cell Transplantation. 2019 Jan 1
2 citations
Hepatotoxicity and Toxicology of In Vivo Lentiviral Vector Administration in Healthy and Liver-Injury Mouse Models
Robert A. Kaiser, Clara T. Nicolas, Kari L. Allen, Jennifer Anne Chilton, Zeji Du, Raymond D. Hickey, Joseph B. Lillegard> ;Human Gene Therapy. Clinical Development. 2019 Jun 17
15 citations
Ex Vivo Hepatocyte Reprograming Promotes Homology‐Directed DNA Repair to Correct Metabolic Disease in Mice After Transplantation
Caitlin J. VanLith, Rebekah M. Guthman, Clara T. Nicolas, Kari L. Allen, Yuanhang Liu, Jennifer Anne Chilton, Zachariah P. Tritz, Scott L. Nyberg, Robert A. Kaiser, Jo...> ;Hepatology Communications. 2019 Apr 1
58 citations
Subsequent pregnancy outcomes after open maternal-fetal surgery for myelomeningocele
William Goodnight, Ozan M. Bahtiyar, Kelly A. Bennett, Stephen P. Emery, Joseph B. Lillegard, Allan J. Fisher, Ruth B. Goldstein, Jillian Jatres, Foong-Yen Lim, Lauren...> ;American Journal of Obstetrics and Gynecology. 2019 Mar 15
10 citations
Fetoscopy-Assisted Percutaneous Decompression of the Distal Trachea and Lungs Reverses Hydrops Fetalis and Fetal Distress in a Fetus with Laryngeal Atresia.
Clara T. Nicolas, David Lynch-Salamon, Ellen M. Bendel-Stenzel, Robert Tibesar, Francois I. Luks, Stephanie A Eyerly-Webb, Joseph B. Lillegard> ;Fetal Diagnosis and Therapy. 2019 Jan 1
4 citations
Lentiviral Vector-mediated Gene Therapy of Hepatocytes Ex Vivo for Autologous Transplantation in Swine.
Robert A. Kaiser, Shennen A. Mao, Jaime Glorioso, Bruce Amiot, Clara T. Nicolas, Kari L. Allen, Zeji Du, Caitlin J. VanLith, Raymond D. Hickey, Scott L. Nyberg, Joseph...> ;Journal of Visualized Experiments. 2018 Nov 4
13 citations
Hepatocyte spheroids as an alternative to single cells for transplantation after ex vivo gene therapy in mice and pig models.
Clara T. Nicolas, Raymond D. Hickey, Kari L. Allen, Zeji Du, Rebekah M. Guthman, Robert A. Kaiser, Bruce Amiot, Aditya Bansal, Mukesh K. Pandey, Lukkana Suksanpaisan, ...> ;Surgery. 2018 Jun 6
22 citations
Curative Ex Vivo Hepatocyte-Directed Gene Editing in a Mouse Model of Hereditary Tyrosinemia Type 1.
Caitlin J. VanLith, Rebekah M. Guthman, Clara T. Nicolas, Kari L. Allen, Zeji Du, Dong Jin Joo, Scott L. Nyberg, Joseph B. Lillegard, Raymond D. Hickey> ;Human Gene Therapy. 2018 Jun 22
13 citations
Chronic Phenotype Characterization of a Large-Animal Model of Hereditary Tyrosinemia Type 1
Faysal Elgilani, Shennen A. Mao, Jaime Glorioso, Meng Yin, Ianko D. Iankov, Anisha Singh, Bruce Amiot, Piero Rinaldo, Ronald J. Marler, Richard L. Ehman, Markus Grompe...> ;The American Journal of Pathology. 2017 Jan 1
47 citations
Curative ex vivo liver-directed gene therapy in a pig model of hereditary tyrosinemia type 1
Raymond D. Hickey, Shennen A. Mao, Jaime Glorioso, Faysal Elgilani, Bruce Amiot, Harvey S. Chen, Piero Rinaldo, Ronald J. Marler, Huailei Jiang, Timothy R. DeGrado, Lu...> ;Science Translational Medicine. 2016 Jul 27
49 citations
Fumarylacetoacetate hydrolase deficient pigs are a novel large animal model of metabolic liver disease
Raymond D. Hickey, Shennen A. Mao, Jaime Glorioso, Joseph B. Lillegard, James E. Fisher, Bruce Amiot, Piero Rinaldo, Cary O. Harding, Ronald J. Marler, Milton J. Fineg...> ;Stem Cell Research. 2014 Jul 1
10 citations
Autologous blood patch for persistent air leak in children
Joseph B. Lillegard, Raelene D. Kennedy, Michael B. Ishitani, Abdalla E. Zarroug, Brad A. Feltis> ;Journal of Pediatric Surgery. 2013 Sep 1
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Press Mentions

How a Young Girl With Spina Bifida Made Medical History...Before BirthOctober 28th, 2022
‘Instant Love’: Formerly Conjoined Twins Now ThrivingApril 1st, 2021
Exemplar Genetics and Mayo Clinic Launch Joint Venture Focused on Development of Human Liver Cells to Advance Medical ResearchDecember 21st, 2018
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Hospital Affiliations

Regions HospitalSaint Paul, Minnesota