JosephDudleyLykinsMD

PubMed

• FromO/GABA-AT, GABA, and T-263 Mutant to Conception of.
  Lykins, J. D., Joseph Lykins, Matthew J Moschitto, Ying Zhou, Ekaterina V Filippova, Hoang V Le, Tadakimi Tomita, Barbara A Fox, David J Bzik, Chunlei Su, Seesandra V ...> ;Iscience. 2024 Jan 19
• CD4T Cell Responses toAre a Double-Edged Sword.
  Lykins, J. D., Kamal El Bissati, Paulette A Krishack, Ying Zhou, Christopher R Weber, Joseph Lykins, Dragana Jankovic, Karen L Edelblum, Laura Fraczek, Harshita Grover...> ;Vaccines. 2023 Sep 14
• The Effect of Fluid Resuscitation Timing in Early Sepsis Resuscitation.
  Hani I Kuttab, Chad G Evans, Joseph D Lykins, Michelle D Hughes, Jason A Kopec, Michael A Hernandez, Michael A Ward> ;Journal of Intensive Care Medicine. 2023 Nov 1
• 1 citations
  Acute cholecystitis secondary toinfection, complicated by sepsis, gallbladder perforation, hepatic abscess and bacteraemia.
  Alexander Goggins, Adam Aston, Jawaid Shaw, Lykins, J. D., Joseph Lykins> ;BMJ Case Reports. 2022 Dec 29
• Building Programs to Eradicate Toxoplasmosis Part III: Epidemiology and Risk Factors.
  Lykins, J. D., Mariangela Soberón Felín, Kanix Wang, Catalina Raggi, Aliya Moreira, Abhinav Pandey, Andrew Grose, Zuleima Caballero, Claudia Rengifo-Herrera, Margarita...> ;Current Pediatrics Reports. 2022 Sep 1
• 1 citations
  Building Programs to Eradicate Toxoplasmosis Part II: Education.
  Lykins, J. D., Mariangela Soberón Felín, Kanix Wang, Aliya Moreira, Andrew Grose, Karen Leahy, Ying Zhou, Fatima Alibana Clouser, Maryam Siddiqui, Nicole Leong, Perpet...> ;Current Pediatrics Reports. 2022 Sep 1
• 1 citations
  Building Programs to Eradicate Toxoplasmosis Part IV: Understanding and Development of Public Health Strategies and Advances "Take a Village".
  Lykins, J. D., Mariangela Soberón Felín, Kanix Wang, Aliya Moreira, Andrew Grose, Karen Leahy, Ying Zhou, Fatima Alibana Clouser, Maryam Siddiqui, Nicole Leong, Perpet...> ;Current Pediatrics Reports. 2022 Jan 1
• 2 citations
  Building Programs to Eradicate Toxoplasmosis Part I: Introduction and Overview.
  Lykins, J. D., Mariangela Soberón Felín, Kanix Wang, Aliya Moreira, Andrew Grose, Karen Leahy, Ying Zhou, Fatima Alibana Clouser, Maryam Siddiqui, Nicole Leong, Perpet...> ;Current Pediatrics Reports. 2022 Jan 1
• 5 citations
  High performance of a novel point-of-care blood test for Toxoplasma infection in women from diverse regions of Morocco.
  Lykins, J. D., Bouchra El Mansouri, Fatima Amarir, François Peyron, El Bachir Adlaoui, Raphaël Piarroux, Joseph D. Lykins, Majda El Abbassi, Nesma Nekkal, Nadia Bouhla...> ;Emerging Microbes & Infections. 2021 Aug 22
• 2 citations
  Fluid Resuscitation in Septic Patients With Comorbid Heart Failure.
  Erron M. Rourke, Hani I. Kuttab, Joseph D. Lykins, Michelle D. Hughes, Eric P. Keast, Jason A. Kopec, Kristen Wroblewski, John Purakal, Michael A. Ward> ;Critical Care Medicine. 2021 Feb 1
• 61 citations
  Evaluation and Predictors of Fluid Resuscitation in Patients With Severe Sepsis and Septic Shock.
  Hani I. Kuttab, Joseph D. Lykins, Michelle D. Hughes, Kristen Wroblewski, Eric P. Keast, Omobolawa Y. Kukoyi, Jason A. Kopec, Stephen Hall, Michael A. Ward> ;Critical Care Medicine. 2019 Nov 1
• 4 citations
  The Effect of Body Mass Index and Weight-Adjusted Fluid Dosing on Mortality in Sepsis.
  Michael A. Ward, Hani I. Kuttab, Joseph D. Lykins, Kristen Wroblewski, Michelle D. Hughes, Eric P. Keast, Jason A. Kopec, Erron M. Rourke, John Purakal> ;Journal of Intensive Care Medicine. 2022 Jan 1
• 101 citations
  Association of Country-wide Coronavirus Mortality with Demographics, Testing, Lockdowns, and Public Wearing of Masks.
  Christopher T. Leffler, Edsel Ing, Joseph D. Lykins, Matthew C. Hogan, Craig A. McKeown, Andrzej Grzybowski> ;The American Journal of Tropical Medicine and Hygiene. 2020 Oct 26
• 15 citations
  Engineering and characterization of a novel Self Assembling Protein for Toxoplasma peptide vaccine in HLA-A*11:01, HLA-A*02:01 and HLA-B*07:02 transgenic mice.
  Kamal El Bissati, Ying Zhou, Sara M. Paulillo, Senthil Kumar Raman, Christopher P. Karch, Steve Reed, Ashley Estes, Amber Estes, Joseph Lykins, Peter Burkhard, Rima Mc...> ;Scientific Reports. 2020 Oct 12
• 15 citations
  Potent Tetrahydroquinolone Eliminates Apicomplexan Parasites
  Martin J. McPhillie, Ying Zhou, Mark Hickman, James Gordon, Christopher R. Weber, Qigui Li, Patty J. Lee, Kangsa Amporndanai, Rachel M. Johnson, Heather Darby, Stuart ...> ;Frontiers in Cellular and Infection Microbiology. 2020 Jun 9
• 7 citations
  Outcomes of hydrocephalus secondary to congenital toxoplasmosis.
  David G. McLone, Richard D. Penn, Charles N. Swisher, Peter Heydemann, Kenneth M. Boyer, A. Gwendolyn Noble, Peter Rabiah, Shawn Withers, Kristen Wroblewski, Theodore ...> ;Journal of Neurosurgery. Pediatrics. 2019 Sep 6
• 9 citations
  Novel Synthetic Polyamines Have Potent Antimalarial Activities in vitro and in vivo by Decreasing Intracellular Spermidine and Spermine Concentrations
  Kamal El Bissati, Henry Redel, Li Min Ting, Joseph D. Lykins, Martin J. McPhillie, Rajendra Upadhya, Patrick M. Woster, Nigel Yarlett, Kami Kim, Louis M. Weiss> ;Frontiers in Cellular and Infection Microbiology. 2019 Feb 14
• 10 citations
  CSGID Solves Structures and Identifies Phenotypes for Five Enzymes in Toxoplasma gondii
  Joseph Lykins, Ekaterina V. Filippova, Andrei S. Halavaty, George Minasov, Ying Zhou, I. Dubrovska, K. Flores, Ludmilla Shuvalova, J. Ruan, Kamal El Bissati, Sarah Dov...> ;Frontiers in Cellular and Infection Microbiology. 2018 Oct 5
• 54 citations
  Global initiative for congenital toxoplasmosis: an observational and international comparative clinical analysis.
  Kamal El Bissati, Pauline Levigne, Joseph D. Lykins, El Bachir Adlaoui, A. Barkat, Amina Berraho, Majda Laboudi, Bouchra El Mansouri, Azeddine Ibrahimi, Mohamed Rhajao...> ;Emerging Microbes & Infections. 2018 Sep 27
• 18 citations
  Rapid, inexpensive, fingerstick, whole-blood, sensitive, specific, point-of-care test for anti-Toxoplasma antibodies.
  Joseph Lykins, Xuan Li, Pauline Levigne, Ying Zhou, Kamal El Bissati, Fatima Clouser, Martine Wallon, Florence Morel, Karen Leahy, Bouchra El Mansouri, Maryam Siddiqui...> ;Plos Neglected Tropical Diseases. 2018 Aug 16
• 31 citations
  Point-of-care testing for Toxoplasma gondii IgG/IgM using Toxoplasma ICT IgG-IgM test with sera from the United States and implications for developing countries.
  Ian J. Begeman, Joseph Lykins, Ying Zhou, Bo Shiun Lai, Pauline Levigne, Kamal El Bissati, Kenneth M. Boyer, Shawn Withers, Fatima Clouser, A. Gwendolyn Noble, Peter R...> ;Plos Neglected Tropical Diseases. 2017 Jun 26
• 32 citations
  Adjuvanted multi-epitope vaccines protect HLA-A*11:01 transgenic mice against Toxoplasma gondii
  Kamal El Bissati, Aziz Alami Chentoufi, Paulette A. Krishack, Ying Zhou, Stuart Woods, Jitender P. Dubey, Lo Vang, Joseph Lykins, Kate E Broderick, Ernest Mui, Yasuhir...> ;JCI Insight. 2016 Sep 22
• 30 citations
  New paradigms for understanding and step changes in treating active and chronic, persistent apicomplexan infections
  Martin J. McPhillie, Ying Zhou, Kamal El Bissati, Jitender P. Dubey, Hernan Lorenzi, Michael J. Capper, Amanda K. Lukens, Mark Hickman, Stephen P. Muench, Shiv K. Verm...> ;Scientific Reports. 2016 Jul 14
• 31 citations
  Understanding Toxoplasmosis in the United States Through “Large Data” Analyses
  Joseph Lykins, Kanix Wang, Kelsey Wheeler, Fatima Clouser, Ashtyn Dixon, Kamal El Bissati, Ying Zhou, Christopher S. Lyttle, Andrey Rzhetsky, Rima McLeod> ;Clinical Infectious Diseases. 2016 Aug 15
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Journal Articles

• Blood Pressure Assessment and Treatment in the Observation Unit  
  Vitto CM, Lykins V JD, Wiles-Lafayette H, Aurora TK., Current Hypertension Reports, 5/20/2022
• Preliminary Analysis of Excess Mortality in India During the COVID-19 Pandemic  
  Leffler CT, Lykins V JD, Das S, Yang E, Konda S., American Journal of Tropical Medicine and Hygiene, 4/4/2022
• The effect of delays in second-dose antibiotics on patients with severe sepsis and septic shock  
  Lykins V JD, Kuttab HI, Rourke EM, Hughes MD, Keast EP, Kopec JA, Ward BL, Pettit NN, Ward MA., American Journal of Emergency Medicine, 3/22/2021
• CSGID Solves Structures and Identifies Phenotypes for Five Enzymes in Toxoplasma gondii  
  Joseph D. Lykins, Ekaterina V. Filippova, Andrei S. Halavaty, George Minasov, Ying Zhou, Ievgeniia Dubrovska, Kristin J. Flores, Ludmilla A. Shuvalova, Jiapeng Ruan, K..., Frontiers in Cellular and Infection Microbiology, 10/5/2018
• Rapid, inexpensive, fingerstick, whole-blood, sensitive, specific, point-of-care test for anti-Toxoplasma antibodies  
  Joseph Lykins, Xuan Li, Pauline Levigne, Ying Zhou, Kamal El Bissati, Fatima Clouser, Martine Wallon, Florence Morel, Karen Leahy, Bouchra El Mansouri, Maryam Siddiqui..., PLoS Neglected Tropical Diseases, 8/17/2018
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