JosephK.WongMD

PubMed

• 29 citations
  Incidence of Severe COVID-19 Illness Following Vaccination and Booster With BNT162b2, mRNA-1273, and Ad26.COV2.S Vaccines.
  J Daniel Kelly, Samuel Leonard, Katherine J Hoggatt, W John Boscardin, Emily N Lum, Tristan A Moss-Vazquez, Raul Andino, Joseph K Wong, Amy Byers, Dawn M Bravata, Phyl...> ;JAMA. 2022 Oct 11
• Novel assays to investigate the mechanisms of latent infection with HIV-2.
  Michael D Lu, Sushama Telwatte, Nitasha Kumar, Fernanda Ferreira, Holly Anne Martin, Gayatri Nikhila Kadiyala, Adam Wedrychowski, Sara Moron-Lopez, Tsui-Hua Chen, Erin...> ;Plos One. 2022 Jan 1
• 6 citations
  ABX464 decreases the total HIV reservoir and HIV transcription initiation in CD4 + T cells from HIV-infected ART-suppressed individuals.
  Sara Moron-Lopez, Silvia Bernal, Joseph K. Wong, Javier Martinez-Picado, Steven A. Yukl> ;Clinical Infectious Diseases. 2021 Aug 26
• 24 citations
  Sudden Cardiac Death and Myocardial Fibrosis, Determined by Autopsy, in Persons with HIV.
  Zian H. Tseng, Ellen Moffatt, Anthony S. Kim, Eric Vittinghoff, Phil Ursell, Andrew J. Connolly, Jeffrey E. Olgin, Joseph K. Wong, Priscilla Y. Hsue> ;The New England Journal of Medicine. 2021 Jun 16
• 22 citations
  Novel RT-ddPCR assays for measuring the levels of subgenomic and genomic SARS-CoV-2 transcripts.
  Sushama Telwatte, Holly Anne Martin, Ryan Marczak, Albert Vallejo-Gracia, G. Renuka Kumar, Victoria Murray, Sulggi A. Lee, Melanie Ott, Joseph K. Wong, Steven A. Yukl> ;Methods. 2021 Apr 18
• 11 citations
  Gag p24 Is a Marker of Human Immunodeficiency Virus Expression in Tissues and Correlates With Immune Response.
  Guoxin Wu, Paul Zuck, Shih Lin Goh, Jeffrey M. Milush, Poonam Vohra, Joseph K. Wong, Ma Somsouk, Steven A. Yukl, Barbara L. Shacklett, Nicolas Chomont, Ashley T. Haase...> ;The Journal of Infectious Diseases. 2021 Nov 16
• 16 citations
  Novel RT-ddPCR assays for simultaneous quantification of multiple noncoding and coding regions of SARS-CoV-2 RNA.
  Sushama Telwatte, Nitasha Kumar, Albert Vallejo-Gracia, G. Renuka Kumar, Chuanyi M. Lu, Melanie Ott, Joseph K. Wong, Steven A. Yukl> ;Journal of Virological Methods. 2021 Jun 1
• 13 citations
  Saliva as a testing specimen with or without pooling for SARS-CoV-2 detection by multiplex RT-PCR test.
  Qing Sun, Jonathan C. Li, Hui Ren, Larry Pastor, Yulia Loginova, Roberta Madej, Kristopher Taylor, Joseph K. Wong, Zhao Zhang, Aiguo Zhang, Chuanyi M. Lu, Michael Y. Sha> ;Plos One. 2021 Feb 1
• Novel RT-ddPCR assays for determining the transcriptional profile of SARS-CoV-2
  Sushama Telwatte, Nitasha Kumar, Albert Vallejo-Gracia, G. Renuka Kumar, Chuanyi M. Lu, Melanie Ott, Joseph K. Wong, Steven A. Yukl> ;Biorxiv. 2021 Jan 12
• 16 citations
  Human splice factors contribute to latent HIV infection in primary cell models and blood CD4+ T cells from ART-treated individuals.
  Sara Moron-Lopez, Sushama Telwatte, Indra Sarabia, Emilie Battivelli, Mauricio Montano, Amanda B. Macedo, Dvir Aran, Atul J. Butte, R. Brad Jones, Alberto Bosque, Eric...> ;Plos Pathogens. 2020 Nov 30
• 12 citations
  Mechanistic differences underlying HIV latency in the gut and blood contribute to differential responses to latency-reversing agents.
  Sushama Telwatte, Peggy Kim, Tsui-Hua Chen, Jeffrey M. Milush, Ma Somsouk, Steven G. Deeks, Peter W. Hunt, Joseph K. Wong, Steven A. Yukl> ;AIDS. 2020 Nov 15
• 31 citations
  Heterogeneity in HIV and cellular transcription profiles in cell line models of latent and productive infection: implications for HIV latency.
  Sushama Telwatte, Sara Moron-Lopez, Dvir Aran, Peggy Kim, Christine L. Hsieh, Sunil K. Joshi, Mauricio Montano, Warner C. Greene, Atul J. Butte, Joseph K. Wong, Steven...> ;Retrovirology. 2019 Nov 11
• 16 citations
  Disruption of latent HIV in vivo during the clearance of actinic keratosis by ingenol mebutate
  Guochun Jiang, Emanual Michael Maverakis, Michelle Y. Cheng, Maher Elsheikh, Claire Deleage, Gema Méndez-Lagares, Michiko Shimoda, Steven A. Yukl, Dennis J. Hartigan-O...> ;JCI Insight. 2019 Apr 4
• 25 citations
  Characterization of the HIV-1 transcription profile after romidepsin administration in ART-suppressed individuals.
  Sara Moron-Lopez, Peggy Kim, Ole S. Søgaard, Martin Tolstrup, Joseph K. Wong, Steven A. Yukl> ;AIDS. 2019 Mar 1
• 68 citations
  Gut and blood differ in constitutive blocks to HIV transcription, suggesting tissue-specific differences in the mechanisms that govern HIV latency.
  Sushama Telwatte, Sulggi A. Lee, Ma Somsouk, Hiroyu Hatano, Christopher C. Baker, Philipp Kaiser, Peggy Kim, Tsui-Hua Chen, Jeffrey M. Milush, Peter W. Hunt, Steven G....> ;Plos Pathogens. 2018 Nov 15
• 203 citations
  HIV latency in isolated patient CD4+ T cells may be due to blocks in HIV transcriptional elongation, completion, and splicing
  Steven A. Yukl, Philipp Kaiser, Peggy Kim, Sushama Telwatte, Sunil K. Joshi, Mai Vu, Harry Lampiris, Joseph K. Wong> ;Science Translational Medicine. 2018 Feb 28
• 85 citations
  HIV latency is reversed by ACSS2-driven histone crotonylation
  Guochun Jiang, Don Nguyen, Nancie M. Archin, Steven A. Yukl, Gema Méndez-Lagares, Yuyang Tang, George Richard Thompson, Dennis J. Hartigan-O'Connor, David M. Margolis,...> ;The Journal of Clinical Investigation. 2018 Mar 1
• 18 citations
  Relative efficacy of T cell stimuli as inducers of productive HIV-1 replication in latently infected CD4 lymphocytes from patients on suppressive cART
  Nadejda Beliakova-Bethell, Marjan Hezareh, Joseph K. Wong, Matthew C. Strain, Mary K. Lewinski, Douglas D. Richman, Celsa A. Spina> ;Virology. 2017 Aug 1
• 24 citations
  Impact of Allogeneic Hematopoietic Stem Cell Transplantation on the HIV Reservoir and Immune Response in 3 HIV-Infected Individuals.
  Kersten K. Koelsch, Thomas A Rasmussen, William J. Hey-Nguyen, Chester F Pearson, Yin Xu, Michelle Bailey, Katherine Marks, Sarah C. Sasson, Mark S Taylor, Robyn Tanta...> ;Journal of Acquired Immune Deficiency Syndromes. 2017 Jul 1
• 16 citations
  HIV Exploits Antiviral Host Innate GCN2-ATF4 Signaling for Establishing Viral Replication Early in Infection.
  Guochun Jiang, Clarissa Santos Rocha, Lauren A. Hirao, Erica A. Mendes, George Richard Thompson, Joseph K. Wong, Satya Dandekar> ;Mbio. 2017 May 2
• 23 citations
  Assays for precise quantification of total (including short) and elongated HIV-1 transcripts
  Philipp Kaiser, Sunil K. Joshi, Peggy Kim, Peilin Li, Hongbing Liu, Andrew P. Rice, Joseph K. Wong, Steven A. Yukl> ;Journal of Virological Methods. 2017 Apr 1
• 147 citations
  Tissue reservoirs of HIV.
  Joseph K. Wong, Steven A. Yukl> ;Current Opinion in HIV and AIDS. 2016 Jul 1
• 139 citations
  Synergistic Reactivation of Latent HIV Expression by Ingenol-3-Angelate, PEP005, Targeted NF-kB Signaling in Combination with JQ1 Induced p-TEFb Activation.
  Guochun Jiang, Erica A. Mendes, Philipp Kaiser, Daniel P. Wong, Yuyang Tang, Ivy Cai, Anne Fenton, Gregory P. Melcher, George Richard Thompson, Joseph K. Wong, Satya D...> ;Plos Pathogens. 2015 Jul 30
• 78 citations
  The Montreal Cognitive Assessment: A Pilot Study of a Brief Screening Tool for Mild and Moderate Cognitive Impairment in HIV-Positive Veterans
  Maggie Chartier, Pierre-Cedric Crouch, Van Tullis, Stephanie Catella, Erin Frawley, Charles Filanosky, Timothy P. Carmody, John R. McQuaid, Harry Lampiris, Joseph K. Wong> ;Journal of the International Association of Providers of AIDS Care. 2015 May 1
• 28 citations
  Site-Specific Differences in T Cell Frequencies and Phenotypes in the Blood and Gut of HIV-Uninfected and ART-Treated HIV+ Adults
  Steven A. Yukl, Amandeep K. Shergill, Valerie Girling, Qingsheng Li, Maudi Killian, Lorrie Epling, Peilin Li, Philipp Kaiser, Ashley T. Haase, Diane V. Havlir, Kenneth...> ;Plos One. 2015 Mar 26
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Journal Articles

• Gut and Blood Differ in Constitutive Blocks to HIV Transcription, Suggesting Tissue-Specific Differences in the Mechanisms That Govern HIV Latency  
  Steven A Yukl, Ma Somsouk, Steven G Deeks, Sulggi Lee, Hiroyu Hatano, Peter W Hunt, Joseph K Wong, PLoS One