JoshuaTRubinMD

General Surgery • Pittsburgh, PA

Surgical Oncology (Other than Breast)

Professor of Surgery, University of Pittsburgh School of Medicine

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Office
5150 Centre Avenue
Pittsburgh, PA 15232
Phone+1 412-692-2852

Fax+1 412-641-1221
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Education & Training

Clinical Center at the National Institutes of HealthFellowship, Complex General Surgical Oncology, 1986 - 1989
University of ConnecticutResidency, Surgery, 1984 - 1985
Beth Israel Deaconess Medical CenterResidency, Surgery, 1979 - 1984
George Washington University School of Medicine and Health SciencesClass of 1979

Certifications & Licensure

PA State Medical License 1990 - 2024
MD State Medical License 1987 - 1991
American Board of Surgery Surgery

Awards, Honors, & Recognition

Fellow (FACS) American College of Surgeons
Top MD Consumers Checkbook

Publications & Presentations

PubMed

4 citations
Maintenance of Certification and Continuing Medical Education: Are They Still Required?
Marissa Howard-McNatt, Michael S. Sabel, Doreen M. Agnese, Farin Amersi, John B. Ammori, Cletus A. Arciero, Russell S. Berman, Laura S. Dominici, R. Y. Fleming, Dale H...> ;Annals of Surgical Oncology. 2019 Aug 16
23 citations
Mathematical modeling in necrotizing enterocolitis--a new look at an ongoing problem.
Jeffrey S. Upperman, Victoria Camerini, Brian Lugo, Ivan Yotov, Joshua Sullivan, Jonathan E. Rubin, Giles Clermont, Ruben Zamora, G. Bard Ermentrout, Henri R. Ford, Yo...> ;Journal of Pediatric Surgery. 2007 Mar 1
6 citations
Disseminated nocardiosis diagnosed by fine needle aspiration biopsy: Quick and accurate diagnostic approach
Kazuya Onuma, Maria Crespo, James H. Dauber, Joshua T. Rubin, Daniel Sudilovsky> ;Diagnostic Cytopathology. 2006 Nov 1
23 citations
Effect of creatine supplementation and a lacto-ovo-vegetarian diet on muscle creatine concentration.
Judith M. Lukaszuk, Robert J. Robertson, Judith E. Arch, Geoffrey E. Moore, Kenneth M. Yaw, David E. Kelley, Joshua T. Rubin, Niall M. Moyna> ;International Journal of Sport Nutrition and Exercise Metabolism. 2002 Sep 1
2 citations
Rectal cancer twenty-one years after treatment of childhood Hodgkin disease
Melvin Deutsch, Michael R. Wollman, Ramesh K. Ramanathan, Joshua T. Rubin> ;Medical and Pediatric Oncology. 2002 Apr 1
8 citations
Potent antitumor effects of intra-arterial injection of fibroblasts genetically engineered to express IL-12 in liver metastasis model of rat: no additional benefit of ...
Takashi Iwazawa, Gar Yang Chau, Takahiro Mori, Keith A. Dookeran, Joshua T. Rubin, Simon C. Watkins, Paul D. Robbins, Michael T. Lotze, Hideaki Tahara> ;Cancer Gene Therapy. 2001 Jan 1
30 citations
Recurrent metastatic renal cell carcinoma presenting as a bleeding gastric ulcer after a complete response to high-dose interleukin-2 treatment.
Borys Mascarenhas, Badrinath R. Konety, Joshua T. Rubin> ;Urology. 2001 Jan 1
1 citations
Human gene marker/therapy clinical protocols.
S A Rosenberg, R M Blaese, M K Brenner, A B Deisseroth, F D Ledley, M T Lotze, J M Wilson, G J Nabel, K Cornetta, J S Economou, S M Freeman, S R Riddell, M Brenner, E ...> ;Human Gene Therapy. 2000 Apr 10
13 citations
Dramatic response of adult wilms tumor to paclitaxel and cisplatin.
Ramesh K. Ramanathan, Joshua T. Rubin, N. Paul Ohori, Chandra P. Belani> ;Medical and Pediatric Oncology. 2000 Apr 1
1 citations
A comparison of locoregional depot and systemic preparations of 9-aminocamptothecin for treatment of liver metastases in a rat tumor model: Superior antitumor activity...
Keith A. Dookeran, Ann Brumfield, Joshua T. Rubin> ;Annals of Surgical Oncology. 1997 Jun 1
25 citations
Prospective randomized trial of lisofylline for the prevention of toxicities of high-dose interleukin 2 therapy in advanced renal cancer and malignant melanoma.
Kim Margolin, Michael B. Atkins, Joseph A. Sparano, Jeffrey A. Sosman, Geoffrey R. Weiss, Michael T. Lotze, James H. Doroshow, James W. Mier, Kevin O'Boyle, Richard I....> ;Clinical Cancer Research. 1997 Apr 1
2 citations
Treatment of hepatic-metastatic colorectal cancer with a chemotherapeutic emulsion: interim results of a phase I trial.
Joshua T. Rubin, Michael T. Lotze, Debbie Rosenfelder, Ann Brumfield, Rodney Howells, Rowena Schwartz, Shawn Sylvestri, John K. Sammon, Klaus M. Bron, Phillip Orens, A...> ;Annals of Surgical Oncology. 1995 Jul 1
11 citations
HLA-DQ1 is associated with clinical response and survival of patients with melanoma who are treated with interleukin-2.
Joshua T. Rubin, Day R, Rene J. Duquesnoy, Simonis B, S. Adams, Lee J, Lotze Mt> ;Therapeutic Immunology. 1995 Feb 1
9 citations
Interleukin-2: Its rationale and role in the treatment of patients with cancer
Joshua T. Rubin> ;Cancer Treatment and Research. 1995 Jan 1
59 citations
Gene Therapy of Cancer: A Pilot Study of IL-4-Gene-Modified Fibroblasts Admixed with Autologous Tumor to Elicit an Immune Response. University of Pittsburgh
Principal Investigators: Michael T. Lotze, Joshua T. Rubin, Investigators:: Sally Carty, Howard Edington, Peter F. Ferson, Rodney J. Landreneau, Barbara A. Pippin, Mit...> ;Human Gene Therapy. 1994 Jan 1
15 citations
INTERLEUKIN-2 : ITS BIOLOGY AND CLINICAL APPLICATION IN PATIENTS WITH CANCER
Joshua T. Rubin> ;Cancer Investigation. 1993 Jan 1
6 citations
New biologic agents come to bat for cancer therapy
Michael T. Lotze, Joshua T. Rubin, Herbert J. Zeh> ;Current Opinion in Oncology. 1992 Dec 1
38 citations
HLA association with response and toxicity in melanoma patients treated with interleukin 2-based immunotherapy.
Francesco M. Marincola, David Venzon, Donald E. White, Joshua T. Rubin, Michael T. Lotze, Toni B. Simonis, Jaikrishna Balkissoon, Steven A. Rosenberg, David R. Parkinson> ;Cancer Research. 1992 Dec 1
73 citations
A prospective randomized trial evaluating prophylactic antibiotics to prevent triple-lumen catheter-related sepsis in patients treated with immunotherapy.
S N Bock, R E Lee, B. Fisher, Joshua T. Rubin, Douglas J. Schwartzentruber, J P Wei, D. P. Callender, James Chih-Hsin Yang, Michael T. Lotze, Philip A. Pizzo> ;Journal of Clinical Oncology. 1990 Jan 1
117 citations
Immunohistochemical Correlates of Response to Recombinant Interleukin-2-based Immunotherapy in Humans
Joshua T. Rubin, Lori J. Elwood, Steven A. Rosenberg, Michael T. Lotze> ;Cancer Research. 1989 Dec 15
44 citations
The effect of intravenous interleukin-2 on brain water content.
Stephen C. Saris, Nicholas J. Patronas, Steven A. Rosenberg, Joseph T. Alexander, Joseph A. Frank, Douglas J. Schwartzentruber, Joshua T. Rubin, David Barba, Edward H....> ;Journal of Neurosurgery. 1989 Aug 1
61 citations
Penetration of recombinant interleukin-2 across the blood-cerebrospinal fluid barrier
Stephen C. Saris, Steven A. Rosenberg, Robert B. Friedman, Joshua T. Rubin, David Barba, Edward H. Oldfield> ;Journal of Neurosurgery. 1988 Jul 1
2219 citations
A progress report on the treatment of 157 patients with advanced cancer using lymphokine-activated killer cells and interleukin-2 or high-dose interleukin-2 alone.
Steven A. Rosenberg, Michael T. Lotze, Linda M. Muul, Alfred E. Chang, Fred P. Avis, Susan F. Leitman, W. Marston Linehan, Cary N. Robertson, Roberta E. Lee, Joshua T....> ;The New England Journal of Medicine. 1987 Apr 9
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Grant Support

Treatmenyt Of Hepatic Metastatic Cancer With Intraarterial Interleukin 2National Center For Research Resources1998–2000
Treatment Of Hepatic-Metastatic Cancer With Intraarterial Infusion Of IL-2National Center For Research Resources1996–1997
Intrapleural Infusion Of IL-2 And Ethiodol For Malignant Pleural EffusionsNational Center For Research Resources1996