JoyNishimeMD

PubMed

• 10 citations
  ROUTE-DEPENDENT NONLINEAR PHARMACOKINETICS OF A NOVEL HIV PROTEASE INHIBITOR: INVOLVEMENT OF ENZYME INACTIVATION
  Jiunn H. Lin, I.-W. Chen, Masato Chiba, Joy A. Nishime, Florencia A. deLuna> ;Drug Metabolism and Disposition. 2000 Apr 1
• 97 citations
  Influence of P-glycoprotein on the transport and metabolism of indinavir in Caco-2 cells expressing cytochrome P-450 3A4.
  Jerome H. Hochman, Masato Chiba, Joy A. Nishime, Masayo Yamazaki, Jiunn H. Lin> ;The Journal of Pharmacology and Experimental Therapeutics. 2000 Jan 1
• 71 citations
  Effect of Dexamethasone on the Intestinal First-Pass Metabolism of Indinavir in Rats: Evidence of Cytochrome P-450 A and p-Glycoprotein Induction
  Jiunn H. Lin, Masato Chiba, I.-W. Chen, Joy A. Nishime, Florencia A. deLuna, Masayo Yamazaki, Yuh J. Lin> ;Drug Metabolism and Disposition. 1999 Oct 1
• 1 citations
  Modulation of rat cytochrome P-450 by an investigational HIV protease inhibitor.
  Joy A. Nishime, Regina W. Wang, Jiunn H. Lin, Masato Chiba> ;Drug Metabolism and Disposition. 1999 Sep 1
• 75 citations
  Hepatic Microsomal Metabolism of Montelukast, a Potent Leukotriene D4 Receptor Antagonist, in Humans
  Masato Chiba, Xin Xu, Joy A. Nishime, Suresh K. Balani, Jiunn H. Lin> ;Drug Metabolism and Disposition. 1997 Sep 1
• Sex-dependent pharmacokinetics of indinavir: in vivo and in vitro evidence.
  Lin JH, Chiba M, Chen IW, Nishime JA, Vastag KJ> ;Drug Metab. Dispos.. 1996-12-01
• 123 citations
  Species differences in the pharmacokinetics and metabolism of indinavir, a potent human immunodeficiency virus protease inhibitor.
  J. H. Lin, Masato Chiba, S. K. Balani, I.-W. Chen, G.-Y. S. Kwei, K. J. Vastag, Joy A. Nishime> ;Drug Metabolism and Disposition. 1996 Oct 1
• Role of cytochrome P450 3A4 in human metabolism of MK-639, a potent human immunodeficiency virus protease inhibitor.
  Chiba M, Hensleigh M, Nishime JA, Balani SK, Lin JH> ;Drug Metab. Dispos.. 1996-03-01
• 49 citations
  Potent and selective inactivation of human liver microsomal cytochrome P-450 isoforms by L-754,394, an investigational human immune deficiency virus protease inhibitor.
  M Chiba, Joy A. Nishime, J H Lin> ;The Journal of Pharmacology and Experimental Therapeutics. 1995 Dec 1
• 16 citations
  Time- and dose-dependent pharmacokinetics of L-754,394, an HIV protease inhibitor, in rats, dogs and monkeys.
  J. H. Lin, M Chiba, I W Chen, K J Vastag, Joy A. Nishime, B D Dorsey, S R Michelson, S L McDaniel> ;The Journal of Pharmacology and Experimental Therapeutics. 1995 Jul 1
• Comparison of imidazole- and 2-methyl imidazole-containing farnesyl-protein transferase inhibitors: interaction with and metabolism by rat hepatic cytochrome P450s.
  Tang, C., Chiba, M., Nishime, J., Hochman, J. H., Chen, I., Williams, T. M., Lin, J. H.> ;Drug Metab Dispos. 2000 Jun
• Comparative in vitro metabolism of indinavir in primates--a unique stereoselective hydroxylation in monkey.
  Chiba, M., Nishime, J. A., Neway, W., Lin, Y., Lin, J. H.> ;Xenobiotica. 2000 Feb
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