JudithA.VoynowMD

Pediatric Pulmonology • Richmond, VA

Professor, Pediatrics, Virginia Commonwealth University School of Medicine

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Office
1000 East Broad Street
Pediatrics
Richmond, VA 23298
Phone+1 804-828-2980

Fax+1 804-828-2983
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Education & Training

Children's Hospital of PhiladelphiaFellowship, Pediatric Pulmonology, 1985 - 1989
Children's Hospital of PhiladelphiaResidency, Pediatrics, 1982 - 1985
Perelman School of Medicine at the University of PennsylvaniaClass of 1982

Certifications & Licensure

VA State Medical License 2013 - 2024
NC State Medical License 1994 - 2021
PA State Medical License 1984 - 2014
NJ State Medical License 1985 - 2005
DC State Medical License 1992 - 1997
American Board of Pediatrics Pediatrics
American Board of Pediatrics Pediatric Pulmonology

Awards, Honors, & Recognition

Regional Top Doctor Castle Connolly, 2014
Fellow (FAAP) American Academy of Pediatrics

Clinical Trials

Prematurity and Respiratory Outcomes Program (PROP) Start of enrollment: 2011 Aug 01
Completed
Gastrin-Releasing Peptide and Bronchopulmonary Dysplasia Start of enrollment: 2012 May 01
Completed

Publications & Presentations

PubMed

Neutrophil elastase activates the release of extracellular traps from COPD blood monocyte-derived macrophages.
Shuo Zheng, Apparao B Kummarapurugu, Gamze B Bulut, Aamer Syed, Le Kang, Judith A Voynow> ;Clinical and Translational Science. 2023 Dec 1
1 citations
Neutrophil elastase decreases SARS-CoV-2 spike protein binding to human bronchial epithelia by clipping ACE-2 ectodomain from the epithelial surface.
Apparao B Kummarapurugu, Adam M Hawkridge, Jonathan Ma, Stephanie Osei, Rebecca K Martin, Shuo Zheng, Judith A Voynow> ;The Journal of Biological Chemistry. 2023 Jun 1
5 citations
Pulmonary function tests in extremely low gestational age infants at one year of age.
Judith A. Voynow, Rui Feng, Clement L. Ren, Andrew M. Dylag, James S. Kemp, Karen M. McDowell, Jack K. Sharp, Paul E. Moore, Eric C. Eichenwald, Howard B. Panitch, Cha...> ;Pediatric Pulmonology. 2021 Nov 14
7 citations
Neutrophil Elastase Triggers the Release of Macrophage Extracellular Traps: Relevance to CF.
Apparao B. Kummarapurugu, Shuo Zheng, Jonathan Ma, Shobha Ghosh, Adam M. Hawkridge, Judith A. Voynow> ;American Journal of Respiratory Cell and Molecular Biology. 2021 Oct 1
58 citations
Neutrophil Elastase and Chronic Lung Disease.
Judith A. Voynow, Meagan Shinbashi> ;Biomolecules. 2021 Jul 21
6 citations
Neutrophil elastase-regulated macrophage sheddome/secretome and phagocytic failure.
Jonathan Ma, Apparao B. Kummarapurugu, Adam M. Hawkridge, Shobha Ghosh, Shuo Zheng, Judith A. Voynow> ;American Journal of Physiology. Lung Cellular and Molecular Physiology. 2021 Jul 14
2 citations
Polysulfated Hyaluronan GlycoMira-1111 Inhibits Elastase and Improves Rheology in Cystic Fibrosis Sputum
Apparao B. Kummarapurugu, Shuo Zheng, Abigail Pulsipher, Justin R. Savage, Jonathan Ma, Bruce K. Rubin, Thomas P Kennedy, Judith A. Voynow> ;American Journal of Respiratory Cell and Molecular Biology. 2021 Feb 1
11 citations
A proposal for the addressing the needs of the pediatric pulmonary work force.
Benjamin Gaston, Theresa A. Laguna, Terry L. Noah, James S. Hagood, Judith A. Voynow, Thomas W. Ferkol, Marc B. Hershenson, Katie Boyne, Angela O. Delecaris, Kristie R...> ;Pediatric Pulmonology. 2020 Aug 1
12 citations
Glycosaminoglycans as Multifunctional Anti-Elastase and Anti-Inflammatory Drugs in Cystic Fibrosis Lung Disease
Judith A. Voynow, Shuo Zheng, Apparao B. Kummarapurugu> ;Frontiers in Pharmacology. 2020 Jul 8
5 citations
Urine gastrin‐releasing peptide in the first week correlates with bronchopulmonary dysplasia and post‐prematurity respiratory disease
Judith A. Voynow, Kimberley A. Fisher, Mary E. Sunday, C M Cotten, Aaron Hamvas, Karen D. Hendricks‐Muñoz, Brenda B. Poindexter, Gloria S. Pryhuber, Clement L. Ren, Ri...> ;Pediatric Pulmonology. 2020 Jan 29
2 citations
Airway Surface Liquid and Impaired Antiviral Defense in Cystic Fibrosis.
Judith A. Voynow, Shuo Zheng> ;American Journal of Respiratory Cell and Molecular Biology. 2020 Jan 1
14 citations
On the Process of Discovering Leads That Target the Heparin-Binding Site of Neutrophil Elastase in the Sputum of Cystic Fibrosis Patients.
Shravan Morla, Nehru Viji Sankaranarayanan, Daniel K. Afosah, Megh Kumar, Apparao B. Kummarapurugu, Judith A. Voynow, Umesh R. Desai> ;Journal of Medicinal Chemistry. 2019 May 10
216 citations
Mucins, Mucus, and Goblet Cells
Jonathan Ma, Bruce K. Rubin, Judith A. Voynow> ;Chest. 2017 Nov 21
39 citations
Cystic Fibrosis Sputum Rheology Correlates With Both Acute and Longitudinal Changes in Lung Function.
Jonathan Ma, Christina Tang, Le Kang, Judith A. Voynow, Bruce K. Rubin> ;Chest. 2018 Aug 1
7 citations
Neutrophil elastase correlates with increased sphingolipid content in cystic fibrosis sputum.
Sophia Karandashova, Apparao B. Kummarapurugu, Shuo Zheng, Le Kang, Shumei Sun, Bruce K. Rubin, Judith A. Voynow> ;Pediatric Pulmonology. 2018 Apr 6
29 citations
Molecular principles for heparin oligosaccharide-based inhibition of neutrophil elastase in cystic fibrosis.
Apparao B. Kummarapurugu, Daniel K. Afosah, Nehru Viji Sankaranarayanan, Rahaman Navaz Gangji, Shuo Zheng, Thomas P. Kennedy, Bruce K. Rubin, Judith A. Voynow, Umesh R...> ;The Journal of Biological Chemistry. 2018 Aug 10
5 citations
The Gut-Lung Axis and Pulmonary Responses to Ozone.
Judith A. Voynow, Karen D. Hendricks-Muñoz> ;American Journal of Respiratory Cell and Molecular Biology. 2018 Aug 31
24 citations
Tracheal aspirate VEGF and sphingolipid metabolites in the preterm infant with later development of bronchopulmonary dysplasia.
Karen D. Hendricks-Muñoz, Jie Xu, Judith A. Voynow> ;Pediatric Pulmonology. 2018 Aug 1
11 citations
Neutrophil elastase increases airway ceramide levels via upregulation of serine palmitoyltransferase
Sophia Karandashova, Apparao B. Kummarapurugu, Shuo Zheng, Charles E. Chalfant, Judith A. Voynow> ;American Journal of Physiology. Lung Cellular and Molecular Physiology. 2018 Jan 1
11 citations
High-Mobility Group Box 1 Upregulates MUC5AC and MUC5B Expression in Primary Airway Epithelial Cells
Apparao B. Kummarapurugu, Shuo Zheng, Julie G. Ledford, Sophia Karandashova, Judith A. Voynow> ;American Journal of Respiratory Cell and Molecular Biology. 2018 Jan 1
132 citations
Bronchopulmonary Dysplasia and Perinatal Characteristics Predict 1-Year Respiratory Outcomes in Newborns Born at Extremely Low Gestational Age: A Prospective Cohort Study
Roberta L. Keller, Rui Feng, Sara B. DeMauro, Thomas W. Ferkol, William D. Hardie, Elizabeth E. Rogers, Timothy P. Stevens, Judith A. Voynow, Scarlett L. Bellamy, Pame...> ;The Journal of Pediatrics. 2017 Aug 1
57 citations
“New” bronchopulmonary dysplasia and chronic lung disease
Judith A. Voynow> ;Paediatric Respiratory Reviews. 2017 Sep 1
19 citations
2-O, 3-O Desulfated Heparin Blocks High Mobility Group Box 1 Release by Inhibition of p300 Acetyltransferase Activity.
Shuo Zheng, Apparao B. Kummarapurugu, Daniel K. Afosah, Nehru Viji Sankaranarayanan, Rio S. Boothello, Umesh R. Desai, Thomas P. Kennedy, Judith A. Voynow> ;American Journal of Respiratory Cell and Molecular Biology. 2017 Jan 1
NAD(P)H quinone oxidoreductase1 regulates neutrophil elastase-induced mucous cell metaplasia. Am JPhysiol Lung Cell Mol Physiol 303: L181–L188, 2012; doi:10.1152/ajplu...
Marisa Meyer, Erin N. Potts-Kant, Andrew J. Ghio, Bernard M. Fischer, W M Foster, Judith A. Voynow> ;American Journal of Physiology. Lung Cellular and Molecular Physiology. 2015 Jul 1
8 citations
Environmental Pollution and the Developing Lung.
Judith A. Voynow, Richard L. Auten> ;Clinical Pulmonary Medicine. 2015 Jul 1
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