Julie-AnMTalanoMD

Pediatric Hematology & Oncology • Milwaukee, WI

Pediatric Hematologic Oncology

Professor, Pediatrics, Medical College of Wisconsin

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Office
8701 W Watertown Plank Rd
Milwaukee, WI 53226
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Education & Training

Medical College of Wisconsin Affiliated HospitalsFellowship, Pediatric Hematology/Oncology, 1999 - 2003
McGaw Medical Center of Northwestern UniversityResidency, Pediatrics, 1995 - 1998
Northwestern University The Feinberg School of MedicineClass of 1995

Certifications & Licensure

WI State Medical License 1999 - 2025
IL State Medical License 1997 - 1999
American Board of Pediatrics Pediatrics
American Board of Pediatrics Pediatric Hematology-Oncology

Awards, Honors, & Recognition

Regional Top Doctor Castle Connolly, 2022
Best Doctors 2012, 2017, 2022
Super Doctor SuperDoctors.com

Clinical Trials

Safety Study of Human Myeloid Progenitor Cells (CLT-008) After Cord Blood Transplant for Hematologic Malignancy Start of enrollment: 2009 Apr 01
Completed
Phase 1
Treosulfan and Fludarabine Phosphate Before Donor Stem Cell Transplant in Treating Patients With Nonmalignant Inherited Disorders Start of enrollment: 2009 Jul 31
Completed
Phase 2
Peripheral Blood Stem Cell Transplantation Using the CliniMACS Device Start of enrollment: 2008 May 01
Completed
Not Applicable
Supersaturated Calcium Phosphate Rinse in Preventing Oral Mucositis in Young Patients Undergoing Autologous or Donor Stem Cell Transplant Start of enrollment: 2011 Mar 01
Completed
Phase 3
MRD Testing Before and After Hematopoietic Cell Transplantation for Pediatric Acute Myeloid Leukemia Start of enrollment: 2011 Oct 01
Completed
Haplo T-Cell Depleted Transplantation in High-Risk Sickle Cell Disease Start of enrollment: 2012 Jan 01
Active, not recruiting
Phase 2
Using Multi-virus Cytotoxic T-cells Following T-Cell Depleted Allogeneic HPCT for Prophylaxis Against EBV, ADV, and CMV Start of enrollment: 2012 Feb 01
Completed
Phase 1
Treosulfan/Fludarabine/Low Dose TBI as a Preparative Regimen for Children With AML/MDS Undergoing Allo HCT Start of enrollment: 2013 Sep 01
Completed
Phase 2
Reduced Intensity Conditioning for Hemophagocytic Syndromes or Selected Primary Immune Deficiencies (BMT CTN 1204) Start of enrollment: 2013 Dec 01
Completed
Phase 2
CAR-20/19-T Cells in Patients With Relapsed/Refractory B Cell ALL Start of enrollment: 2020 Oct 16
Recruiting
Phase 1
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Publications & Presentations

PubMed

1 citations
Survival in primary hemophagocytic lymphohistiocytosis, 2016 to 2021: etoposide is better than its reputation.
Svea Böhm, Katharina Wustrau, Jana Pachlopnik Schmid, Seraina Prader, Martina Ahlmann, Joanne Yacobovich, Rita Beier, Carsten Speckmann, Wolfgang Behnisch, Marianne If...> ;Blood. 2024 Mar 7
Tisagenlecleucel utilisation and outcomes across refractory, first relapse and multiply relapsed B-cell acute lymphoblastic leukemia: a retrospective analysis of real-...
Valentin Barsan, Yimei Li, Snehit Prabhu, Christina Baggott, Khanh Nguyen, Holly Pacenta, Christine L Phillips, Jenna Rossoff, Heather Stefanski, Julie-An Talano, Amy ...> ;Eclinicalmedicine. 2023 Nov 1
Practice Preferences for Consolidative Hematopoietic Stem Cell Transplantation Following Tisagenlecleucel in Children and Young Adults with B Cell Acute Lymphoblastic ...
Amy Moskop, Lena E Winestone, Christina Baggott, Julie-An Talano, Deborah Schiff, Jenna Rossoff, Arunkumar Modi, Michael R Verneris, Theodore W Laetsch, Liora Schultz,...> ;Transplantation and Cellular Therapy. 2024 Jan 1
Haplo ever after: haplo PTCy for children.
Julie-An Talano, Larisa Broglie> ;Blood Advances. 2023 Sep 26
No impact of CD34cell dose on outcome among children undergoing autologous hematopoietic stem cell transplant for high-risk neuroblastoma.
Tristan E Knight, Kwang Woo Ahn, Kyle M Hebert, Rasha Atshan, Donna A Wall, Kanhatai Chiengthong, Troy C Lund, Tim Prestidge, Hemalatha G Rangarajan, Christopher C Dvo...> ;Bone Marrow Transplantation. 2023 Dec 1
1 citations
Alemtuzumab and CXCL9 levels predict likelihood of sustained engraftment after reduced-intensity conditioning HCT.
Ashley V Geerlinks, Brooks Scull, Christa Krupski, Ryan Fleischmann, Michael A Pulsipher, Mary Eapen, James A Connelly, Catherine M Bollard, Sung-Yun Pai, Christine N ...> ;Blood Advances. 2023 Jul 25
1 citations
HLH-like toxicities predict poor survival after the use of tisagenlecleucel in children and young adults with B-ALL.
Kevin O McNerney, Stephanie J Si Lim, Kyle Ishikawa, Alexandra Dreyzin, Anant Vatsayan, John J Chen, Christina Baggott, Snehit Prabhu, Holly L Pacenta, Christine Phili...> ;Blood Advances. 2023 Jun 27
20 citations
Higher doses of tisagenlecleucel are associated with improved outcomes: a report from the pediatric real-world CAR consortium.
Heather E Stefanski, Anne Eaton, Christina Baggott, Jenna Rossoff, Michael R Verneris, Snehit Prabhu, Holly L Pacenta, Christine L Phillips, Julie-An Talano, Amy Mosko...> ;Blood Advances. 2023 Feb 28
22 citations
Outcomes After Nonresponse and Relapse Post-Tisagenlecleucel in Children, Adolescents, and Young Adults With B-Cell Acute Lymphoblastic Leukemia.
Liora M Schultz, Anne Eaton, Christina Baggott, Jenna Rossoff, Snehit Prabhu, Amy K Keating, Christa Krupski, Holly Pacenta, Christine L Philips, Julie-An Talano, Amy ...> ;Journal of Clinical Oncology. 2023 Jan 10
5 citations
SARS-CoV-2 infections in pediatric and young adult recipients of chimeric antigen receptor T-cell therapy: an international registry report.
Kevin Owen McNerney, Rebecca M Richards, Paibel Aguayo-Hiraldo, Friso G Calkoen, Julie-An Talano, Amy Moskop, Adriana Balduzzi, Jennifer Krajewski, Hema Dave, Anant Va...> ;Journal for Immunotherapy of Cancer. 2023 Jan 1
Mediport use as an acceptable standard for CAR T cell infusion.
Toner, K. N., Maya Eylon, Snehit Prabhu, Samuel John, Maxwell J M King, Dhruv Bhatt, Kevin J Curran, Courtney Erickson, Nicole A Karras, Christine L Phillips, Prakash ...> ;Frontiers in Immunology. 2023 Jan 1
The impacts of total body irradiation on umbilical cord blood hematopoietic stem cell transplantation.
Hao Wang, Kristin N Berger, Elizabeth L Miller, Wei Fu, Larisa Broglie, Frederick D Goldman, Heiko Konig, Su Jin Lim, Arthur S Berg, Julie-An Talano, Melanie A Comito,...> ;Therapeutic Advances in Hematology. 2023 Jan 1
Manufacture and Characterization of Good Manufacturing Practice-Compliant SARS-COV-2 Cytotoxic T Lymphocytes.
Yaya Chu, Jordan Milner, Margaret Lamb, Elena Maryamchik, Olivia Rigot, Janet Ayello, Lauren Harrison, Rosemarie Shaw, Gregory K Behbehani, Elaine R Mardis, Katherine ...> ;The Journal of Infectious Diseases. 2023 Mar 28
7 citations
KIR-favorable TCR-αβ/CD19-depleted haploidentical HCT in children with ALL/AML/MDS: primary analysis of the PTCTC ONC1401 trial.
Michael A Pulsipher, Kwang W Ahn, Nancy J Bunin, Nahal Lalefar, Eric Anderson, Allyson Flower, Mitchell S Cairo, Julie-An Talano, Sonali Chaudhury, Carrie L Kitko, Jam...> ;Blood. 2022 Dec 15
15 citations
Haploidentical bone marrow transplantation in patients with relapsed or refractory severe aplastic anaemia in the USA (BMT CTN 1502): a multicentre, single-arm, phase ...
Amy E DeZern, Mary Eapen, Juan Wu, Julie-An Talano, Melhem Solh, Blachy J Dávila Saldaña, Chatchada Karanes, Mitchell E Horwitz, Kanwaldeep Mallhi, Sally Arai, Nosha F...> ;The Lancet. Haematology. 2022 Sep 1
20 citations
Real-world use of tisagenlecleucel in infant acute lymphoblastic leukemia.
Amy Moskop, Lauren Pommert, Christina Baggott, Snehit Prabhu, Holly L Pacenta, Christine L Phillips, Jenna Rossoff, Heather E Stefanski, Julie-An Talano, Steve P Margo...> ;Blood Advances. 2022 Jul 26
1 citations
Significant improvement of child physical and emotional functioning after familial haploidentical stem cell transplant.
Susan K Parsons, Angie Mae Rodday, Ruth Ann Weidner, Erin Morris, Suzanne Braniecki, Shalini Shenoy, Julie-An Talano, Theodore B Moore, Anne Panarella, Allyson Flower,...> ;Bone Marrow Transplantation. 2022 Apr 1
65 citations
Disease Burden Affects Outcomes in Pediatric and Young Adult B-Cell Lymphoblastic Leukemia After Commercial Tisagenlecleucel: A Pediatric Real-World Chimeric Antigen R...
Liora M Schultz, Christina Baggott, Snehit Prabhu, Holly L Pacenta, Christine L Phillips, Jenna Rossoff, Heather E Stefanski, Julie-An Talano, Amy Moskop, Steven P Mar...> ;Journal of Clinical Oncology. 2022 Mar 20
9 citations
Unrelated donor α/β T cell- and B cell-depleted HSCT for the treatment of pediatric acute leukemia.
Allison Barz Leahy, Yimei Li, Julie-An Talano, Caitlin W Elgarten, Alix E Seif, Yongping Wang, Bryon Johnson, Dimitri S Monos, Stephan Kadauke, Timothy S Olson, Jason ...> ;Blood Advances. 2022 Feb 22
Donor chimerism and immune reconstitution following haploidentical transplantation in sickle cell disease.
Yaya Chu, Julie-An Talano, Lee Ann Baxter-Lowe, James W Verbsky, Erin Morris, Harshini Mahanti, Janet Ayello, Carolyn Keever-Taylor, Bryon Johnson, Rona S Weinberg, Qi...> ;Frontiers in Immunology. 2022 Jan 1
GATA2 deficiency detected by newborn screening for SCID: A case report.
Alejandra Escobar Vasco, Larisa Broglie, Julie-An Talano, John Routes, James Verbsky, Allison Remiker> ;Frontiers in Pediatrics. 2022 Jan 1
4 citations
Out-of-specification tisagenlecleucel does not compromise safety or efficacy in pediatric acute lymphoblastic leukemia.
Jenna Rossoff, Christina Baggott, Snehit Prabhu, Holly L Pacenta, Christine L Phillips, Heather E. Stefanski, Julie-An Talano, Amy Moskop, Steven P. Margossian, Michae...> ;Blood. 2021 Nov 25
28 citations
Tisagenlecleucel Outcomes in Relapsed/Refractory Extramedullary ALL: A Pediatric Real World CAR Consortium Report.
Vanessa A Fabrizio, Christine L Phillips, Adam Lane, Christina Baggott, Snehit Prabhu, Emily Egeler, Sharon Mavroukakis, Holly L Pacenta, Jenna Rossoff, Heather E. Ste...> ;Blood Advances. 2021 Nov 18
37 citations
Optimal fludarabine lymphodepletion is associated with improved outcomes following CAR T-cell Therapy.
Vanessa A Fabrizio, Jaap Jan Boelens, Audrey Mauguen, Christina Baggott, Snehit Prabhu, Emily Egeler, Sharon Mavroukakis, Holly L Pacenta, Christine L Phillips, Jenna ...> ;Blood Advances. 2021 Nov 17
59 citations
Standardizing Definitions of Hematopoietic Recovery, Graft Rejection, Graft Failure, Poor Graft Function, and Donor Chimerism in Allogeneic Hematopoietic Cell Transpla...
Mohamed A. Kharfan-Dabaja, Ambuj Kumar, Ernesto Ayala, Mahmoud Aljurf, Taiga Nishihori, Rebecca A. Marsh, Lauri Burroughs, Navneet S. Majhail, A. Samer Al-Homsi, Zaid ...> ;Transplantation and Cellular Therapy. 2021 Aug 1
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Abstracts/Posters

Sustained Donor Chimerism and Rapid Immune Cell Reconstitution Following Familial Haploidentical (FHI) CD34 Enriched Stem Cell Transplantation with Pbmnc Addback in Pa...
Julie-An Talano, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
Next Generation Sequence Minimal Residual Disease (NGS-MRD) Predicts Outstanding Event Free Survival (EFS) Regardless of Hematopoietic Cell Transplantation (HCT) Prepa...
Julie-An Talano, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019

Lectures

Significantly Improved Long Term Health Related Quality of Life (HRQL) and Neurocognition Following Familial Haploidentical Stem Cell Transplantation (HISCT) Utilizing...
2018 ASH Annual Meeting - San Diego, CA - 12/1/2018