Kai-ChunYangMD

PubMed

• Multiplexed Functional Assessments ofVariants in Human Cardiomyocytes.
  Clayton E Friedman, Shawn Fayer, Sriram Pendyala, Wei-Ming Chien, Alexander Loiben, Linda Tran, Leslie S Chao, Ashley McKinstry, Dania Ahmed, Stephen D Farris, April S...> ;Circulation. Genomic and Precision Medicine. 2024 Apr 1
• 1 citations
  CRaTER enrichment for on-target gene editing enables generation of variant libraries in hiPSCs.
  Clayton E Friedman, Shawn Fayer, Sriram Pendyala, Wei-Ming Chien, Alexander Loiben, Linda Tran, Leslie S Chao, Ashley Mckinstry, Dania Ahmed, Elaheh Karbassi, Aidan M ...> ;Journal of Molecular and Cellular Cardiology. 2023 Jun 1
• 1 citations
  Cardiomyocyte Apoptosis Is Associated with Contractile Dysfunction in Stem Cell Model ofE848G Hypertrophic Cardiomyopathy.
  Alexander M Loiben, Wei-Ming Chien, Clayton E Friedman, Leslie S-L Chao, Gerhard Weber, Alex Goldstein, Nathan J Sniadecki, Charles E Murry, Kai-Chun Yang> ;International Journal of Molecular Sciences. 2023 Mar 3
• Cardiomyocyte apoptosis contributes to contractile dysfunction in stem cell model ofE848G hypertrophic cardiomyopathy.
  Alexander M Loiben, Wei-Ming Chien, Clayton E Friedman, Leslie S-L Chao, Gerhard Weber, Alex Goldstein, Nathan Sniadecki, Charles E Murry, Kai-Chun Yang> ;Biorxiv. 2023 Jan 25
• 2 citations
  Generation of human iPSC line from an arrhythmogenic cardiomyopathy patient with a DSP protein-truncating variant.
  Alexander Loiben, Clayton E Friedman, Wei-Ming Chien, April Stempien-Otero, Shin Lin, Kai-Chun Yang> ;Stem Cell Research. 2023 Feb 1
• 50 citations
  Novel Adult-Onset Systolic Cardiomyopathy Due to MYH7 E848G Mutation in Patient-Derived Induced Pluripotent Stem Cells
  Kai Chun Yang, Astrid Breitbart, Willem J. de Lange, Peter Hofsteen, Akiko Futakuchi-Tsuchida, Joy Xu, Cody Schopf, Maria V. Razumova, Alex Jiao, Robert J. Boucek, Lil...> ;JACC. Basic to Translational Science. 2018 Dec 31
• 57 citations
  Isolation and Mechanical Measurements of Myofibrils from Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes
  Josè Manuel Pioner, Alice Ward Racca, Jordan M. Klaiman, Kai Chun Yang, Xuan Guan, Lil Pabon, Veronica Muskheli, Rebecca J. Zaunbrecher, Jesse Macadangdang, Mark Y. Je...> ;Stem Cell Reports. 2016 Jun 14
• Tumor necrosis factor receptor-associated factor 2 mediates mitochondrial autophagy.
  Yang, K. C.,Ma, X.,Liu, H.,Murphy, J.,Barger, P. M.,Mann, D. L.,Diwan, A.> ;Circ Heart Fail. 2014 Oct 24
• 77 citations
  Mechanical Unloading Activates FoxO3 to Trigger Bnip3-Dependent Cardiomyocyte Atrophy
  Dian J. Cao, Nan Jiang, Andrew G Blagg, Janet L. Johnstone, Raj B. Gondalia, Misook Oh, Xiang Luo, Kai-Chun Yang, John M. Shelton, Beverly A. Rothermel, Thomas G. Gill...> ;Journal of the American Heart Association. 2013 Apr 8
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