
Kara Gross Margolis MD
Pediatric Nutrition
Associate Professor of Molecular Pathobiology, Cell Biology and Pediatrics at NYU Langone, NYU and the NYU College of Dentistry Associate Director, NYU Pain Research Center
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3959 BroadwayNew York, NY 10032
Phone+1 212-305-5903
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Summary
- Kara Margolis is the Director of the NYU Pain Research Center and an Associate Professor of Pediatrics, Molecular Pathobiology and Cell biology at New York University, the NYU College of Dentistry and the NYU Grossman School of Medicine.
Dr. Margolis completed a pediatrics residency at the Albert Einstein College of Medicine and a pediatric gastroenterology fellowship at Harvard Medical School. Prior to joining NYU, she held a tenured position as an Associate Professor of Pediatrics at Columbia University.
Dr. Margolis is a pediatric gastroenterologist and physician-scientist with recognized clinical and scientific expertise in disorders that affect the gut and the brain, including disorders of gut brain interactions (DGBI) and well as gastrointestinal problems in children with autism spectrum disorders.
In the laboratory, Dr. Margolis leads clinical, translational and basic science research programs whose themes center around gut serotonin signaling mechanisms in gut-brain axis conditions. Her current major focuses are on the role on gut serotonin in mood dysfunction and related abdominal pain disorders, the effects of in utero medication exposures on the development of DGBIs and the gastrointestinal and behavioral outcomes in children with Autism after nutritional interventions.
Kara's work has been published in journals including Gastroenterology, Gut, JCI, PNAS, Cell and Cell Stem Cell. Her work is currently funded by the NIH and the Department of Defense as several foundations and pharmaceutical companies.
Education & Training
- Boston Children’s Hospital//Boston Medical CenterFellowship, Pediatric Gastroenterology, 2004 - 2007
- Montefiore Medical Center/Albert Einstein College of MedicineResidency, Pediatrics, 2001 - 2004
- Jacobs School of Medicine and Biomedical Sciences at the University at BuffaloClass of 2001
Certifications & Licensure
- NY State Medical License 2007 - 2026
- MA State Medical License 2005 - 2008
- American Board of Pediatrics Pediatric Gastroenterology
Publications & Presentations
PubMed
- Sugar in the First 1000 Days of Life: Link to Increased Chronic Disease Risks.Sik Yu So, Kara Gross Margolis
Gastroenterology. 2025-05-01 - 1 citationsIntestinal Epithelial Serotonin as a Novel Target for Treating Disorders of Gut-Brain Interaction and Mood.Lin Y Hung, Nuno D Alves, Andrew Del Colle, Ardesheer Talati, Sarah A Najjar
Gastroenterology. 2025-04-01 - Sweet Tooth? Blame It on Your Dessert Brain!Chalystha Yie Qin Lee, Kara Gross Margolis
Gastroenterology. 2025-03-19
Press Mentions
- Antidepressants in Pregnancy Linked to Children’s Gut Issues—What’s Known and a Potential Treatment ApproachApril 4th, 2025
- New Study Explores Safer Antidepressants for Pregnant WomenJanuary 27th, 2025
- SSRI Antidepressants May Cause Fewer Side Effects When Targeted to the GutDecember 12th, 2024
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Grant Support
- Differentiating the roles and underlying mechanisms of serotonin in the gut epithelium and ENS to create a novel drug delivery system to treat disorders of gut-brain interaction and mood dysfunctionNEW YORK UNIVERSITY2024–2029
- A Prospective Study Examining the Role of Gestational SSRI Exposure in the Development of Functional Gastrointestinal DisordersNEW YORK UNIVERSITY2021–2025
- Linkage of s100a10 (p11) to enteric 5-HT4-mediated serotonergic signaling roles in GI motility, enteric nervous system development, and co-morbid dysfunction of gut and brainNEW YORK UNIVERSITY2021–2025
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