KaramKhaddourMD

PubMed

• Patterns of initial distant metastases in 151 patients undergoing surveillance for treated Merkel cell carcinoma.
  Emily Y Kim, Mofei Liu, Anita Giobbie-Hurder, Karam Khaddour, Ann W Silk, Manisha Thakuria, Furkan Bahar> ;Journal of the European Academy of Dermatology and Venereology. 2024 Mar 3
• 2 citations
  Novel immunotherapeutic options for BCG-unresponsive high-risk non-muscle-invasive bladder cancer.
  Zein Alabdin Hannouneh, Amjad Hijazi, Alaa Aldeen Alsaleem, Siwan Hami, Nina Kheyrbek, Fadi Tanous, Karam Khaddour, Abdulfattah Abbas, Zuheir Alshehabi> ;Cancer Medicine. 2023 Dec 1
• Determining PARP Inhibition as a Treatment Strategy in Melanoma Based on Homologous Recombination Deficiency-Related Loss of Heterozygosity.
  Alice Zhou, Omar Butt, Michael Ansstas, Elizabeth Mauer, Karam Khaddour, George Ansstas> ;Journal of the National Comprehensive Cancer Network. 2023 Jul 1
• The Lung Microbiome in Carcinogenesis and Immunotherapy Treatment.
  Kathleen Kennedy, Karam Khaddour, Nithya Ramnath, Frank Weinberg> ;Cancer Journal. 2023 Mar 23
• Myo1e overexpression in lung adenocarcinoma is associated with increased risk of mortality.
  Ignacio Jusue-Torres, Richies Tiv, Julio C Ricarte-Filho, Apurva Mallisetty, Leglys Contreras-Vargas, Maria Jose Godoy-Calderon, Karam Khaddour, Kathleen Kennedy, Klar...> ;Scientific Reports. 2023 Mar 13
• Addendum: Successful administration of sequential TVEC and pembrolizumab followed by Temozolomide in immunotherapy refractory intracranial metastatic melanoma with acq...
  Karam Khaddour, Joshua Dowling, Jiayi Huang, Martha Council, David Chen, Lynn Cornelius, Tanner Johanns, Sonika Dahiya, George Ansstas> ;Oncotarget. 2023 Feb 11
• 1 citations
  Case Report: Stereotactic body radiation treatment for immunotherapy escaped oligometastatic progression in cutaneous melanoma and merkel cell carcinoma.
  Karam Khaddour, Alice Zhou, Omar Butt, Jiayi Huang, George Ansstas> ;Frontiers in Oncology. 2023 Jan 1
• Dynamin-2 deficiency causes age- and sex-dependent neutropenia and myelodysplasia in mice.
  Alexander J Willis, Seth J Corey, Carlos Murga-Zamalloa, Saman S Karimi, Karam Khaddour, John Quigley, Elizabeth A Eklund, Yolande Chen> ;Blood Advances. 2023 Apr 25
• 3 citations
  The Prognostic and Therapeutic Potential of DNA Damage Repair Pathway Alterations and Homologous Recombination Deficiency in Lung Cancer.
  Karam Khaddour, Manuel Felipe Fernandez, Marsel Khabibov, Airat Garifullin, Danielle Dressler, Iuliia Topchu, Jyoti D Patel, Frank Weinberg, Yanis Boumber> ;Cancers. 2022 Oct 28
• 24 citations
  Signaling pathways and therapeutic approaches in glioblastoma multiforme (Review).
  Marsel Khabibov, Airat Garifullin, Yanis Boumber, Karam Khaddour, Manuel Fernandez, Firat Khamitov, Larisa Khalikova, Natalia Kuznetsova, Oleg Kit, Leonid Kharin> ;International Journal of Oncology. 2022 Jun 1
• 7 citations
  Prolonged response of recurrent-wild-type glioblastoma to laser interstitial thermal therapy with pembrolizumab.
  Helen Hwang, Jiayi Huang, Karam Khaddour, Omar H Butt, George Ansstas, Jie Chen, Ruth Gn Katumba, Albert H Kim, Eric C Leuthardt, Jian L Campian> ;CNS Oncology. 2022 Mar 1
• 3 citations
  Case report: Real-world experience using a personalized cancer-specific circulating tumor DNA assay in different metastatic melanoma scenarios.
  Karam Khaddour, Alice Zhou, Omar H Butt, Griffin Budde, Allyson Koyen Malashevich, George Ansstas> ;Frontiers in Oncology. 2022 Jan 1
• 13 citations
  Melanoma Targeted Therapies beyond BRAF-Mutant Melanoma: Potential Druggable Mutations and Novel Treatment Approaches.
  Karam Khaddour, Lucas Maahs, Ana Maria Avila-Rodriguez, Yazan Maamar, Sami Samaan, George Ansstas> ;Cancers. 2021 Nov 22
• 1 citations
  Severe Psychiatric Symptoms in a Patient With EGFR Exon-20 Insertion Mutation Receiving Mobocertinib: A Case Report.
  Josette Kamel, Natalie Meeder, Sandra Cuellar, David Chan, Michael Huber, Mary Pasquinelli, Alicia Hulbert, Karam Khaddour, Lawrence Eric Feldman> ;JTO Clinical and Research Reports. 2021 Nov 1
• 7 citations
  Clinical outcomes and longitudinal circulating tumor DNA changes after treatment with nivolumab and olaparib in immunotherapy relapsed melanoma with detected homologou...
  Karam Khaddour, Michael Ansstas, George Ansstas> ;Cold Spring Harbor Molecular Case Studies. 2021 Oct 1
• 29 citations
  Targeting the Epidermal Growth Factor Receptor in EGFR-Mutated Lung Cancer: Current and Emerging Therapies.
  Karam Khaddour, Sushma Jonna, Alexander Y. Deneka, Jyoti D. Patel, Mohamed E. Abazeed, Erica A. Golemis, Hossein Borghaei, Yanis Boumber> ;Cancers. 2021 Jun 24
• 2 citations
  The predictive value of absolute lymphocyte counts on tumor progression and pseudoprogression in patients with glioblastoma
  Jing Xi, Bilal Hassan, Ruth Katumba, Karam Khaddour, Akshay Govindan, Jingqin Luo, Jiayi Huang, Jian Campian> ;BMC Cancer. 2021 Mar 16
• 3 citations
  BRAF-MEK inhibitors as steroid-sparing bridge prior to checkpoint blockade therapy in symptomatic intracranial melanoma
  Karam Khaddour, Tanner M. Johanns, George Ansstas> ;Melanoma Management. 2021 Feb 15
• 6 citations
  Normalization of electroretinogram and symptom resolution of melanoma-associated retinopathy with negative autoantibodies after treatment with programmed death-1 (PD-1...
  Karam Khaddour, Sangeeta Khanna, Michael Ansstas, Ishaan Jakhar, Sonika Dahiya, George Ansstas> ;Cancer Immunology, Immunotherapy. 2021 Feb 5
• 6 citations
  Mutation clearance and complete radiologic resolution of immunotherapy relapsed metastatic melanoma after treatment with nivolumab and olaparib in a patient with homol...
  Karam Khaddour, Michael Ansstas, John Visconti, George Ansstas> ;Annals of Oncology. 2021 Feb 1
• 7 citations
  Successful administration of sequential TVEC and pembrolizumab followed by Temozolomide in immunotherapy refractory intracranial metastatic melanoma with acquired B2M ...
  Karam Khaddour, Joshua L. Dowling, Jiayi Huang, David Y. Chen, Lynn A. Cornelius, Tanner M. Johanns, Sonika Dahiya, George Ansstas> ;Oncotarget. 2020 Dec 29
• 15 citations
  Successful Use of BRAF/MEK Inhibitors as a Neoadjuvant Approach in the Definitive Treatment of Papillary Craniopharyngioma.
  Karam Khaddour, Michael R. Chicoine, Jiayi Huang, Sonika Dahiya, George Ansstas> ;Journal of the National Comprehensive Cancer Network. 2020 Dec 2
• 4 citations
  Metachronous cutaneous squamous cell carcinoma in a young patient as the only presenting symptom to uncover Lynch syndrome with MLH1 Germline mutation
  Karam Khaddour, Ryan C. Fields, Michael Ansstas, Ilana S. Rosman, George Ansstas> ;Hereditary Cancer in Clinical Practice. 2020 Nov 16
• 33 citations
  The Landscape of Novel Therapeutics and Challenges in Glioblastoma Multiforme: Contemporary State and Future Directions.
  Karam Khaddour, Tanner M. Johanns, George Ansstas> ;Pharmaceuticals. 2020 Nov 14
• 6 citations
  Durable remission after rechallenge with ipilimumab and nivolumab in metastatic Merkel cell carcinoma refractory to avelumab: Any role for sequential immunotherapy?
  Karam Khaddour, Ilana S. Rosman, Farrokh Dehdashti, George Ansstas> ;The Journal of Dermatology. 2021 Feb 1
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Lectures

• IGF-1 and IL-6 as predictors of sarcopenia in non-metastatic colorectal cancer patients. 
  ASCO Annual Meeting 2019 - Chicago, IL - 5/31/2019