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1515 Holcombe Blvd Unit 1202M.D. Anderson Cancer CenterHouston, TX 77030
Phone+1 713-563-8495
Dr. Hoffman is on Doximity
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Education & Training
Mass General Brigham/Brigham and Women's Hospital/Massachusetts General Hospital/Harvard Medical SchoolResidency, Radiation Oncology, 2005 - 2009
MedStart Georgetown University HospitalInternship, Transitional Year, 2004 - 2005
Duke University School of MedicineClass of 2004
Certifications & Licensure
FL State Medical License 2021 - Present
TX State Medical License 2009 - 2026
OK State Medical License 2020 - 2021
MA State Medical License 2005 - 2010
VA State Medical License 2004 - 2005
American Board of Radiology Radiation Oncology
Awards, Honors, & Recognition
- CMS Meaningful Use Stage 1 Certification ClinicStation, UT MD Anderson Cancer Center, 2013-2015
Clinical Trials
- Abiraterone, Radiotherapy and Short-Term Androgen Deprivation in Unfavorable Localized Prostate Cancer Start of enrollment: 2014 Jan 17
- Hypofractionated vs. Conventional Regional Nodal Radiation Therapy for Patients With Invasive Breast Cancer Start of enrollment: 2017 Feb 23
Roles: Contact, Principal Investigator
- Pragmatic Randomized Trial of Proton vs. Photon Therapy for Patients With Non-Metastatic Breast Cancer: A Radiotherapy Comparative Effectiveness (RADCOMP) Consortium Trial Start of enrollment: 2016 Apr 06
Roles: Contact
Publications & Presentations
PubMed
- Long-term oncological outcomes from a prospective cohort of patients with localised prostate cancer.Avi S Baskin, Karen E Hoffman, David F Penson, Li-Ching Huang, Zhiguo Zhao
BJU International. 2026-12-01 - 1 citationsAssociations Between Cardiac Radiation Dose-Volume Metrics and Health-Related Quality of Life for Patients With Breast Cancer on the RadComp Trial.Jean L Wright, Kyunga Ko, Walter Kenworthy, Walter Bosch, William Straube
International Journal of Radiation Oncology, Biology, Physics. 2026-11-15 - 7 citationsDevelopment and Validation of a Multimodal Artificial Intelligence-derived Digital Pathology-based Biomarker Predicting Metastasis Among Patients with Biochemical Recu...Todd M Morgan, Yi Ren, Siyi Tang, Wouter Zwerink, Emmalyn Chen
European Urology. 2026-11-01
Journal Articles
- Association of Transforming Growth Factor Β Polymorphism C−509T with Radiation-Induced Fibrosis Among Patients with Early-Stage Breast CancerA Secondary Analysis of a ...Karen E Hoffman, Elizabeth S Bloom, Pamela J Schlembach, Thomas A Buchholz, Benjamin D Smith, Wendy A Woodward, Welela Tereffe, Simona F Shaitelman, Michael C Stauder, JAMA
- The Implications of Ageing and Life Expectancy in Prostate Cancer TreatmentJohn W Davis, Spyridon Basourakos, Jeri Kim, Karen E Hoffman, Nature
Press Mentions
Survival Benefit Evades Pelvic Radiation in Less Aggressive Prostate CancerOctober 2nd, 2025- Stereotactic Body Radiation Therapy (SBRT) for Prostate Cancer: What to KnowMarch 5th, 2025
- No Improvement in Lymphedema with Hypofractionated Nodal RT for Breast CancerOctober 1st, 2024
Professional Memberships
- Member
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