KarenPuopoloMDPhD

Neonat/Perinatology • Philadelphia, PA

Neonatal Infections

Associate Professor of Clinical Pediatrics, University of Pennsylvania

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Office
800 Spruce St
Pennsylvania Hospital, CHOP Newborn Care
Philadelphia, PA 19107
Phone+1 215-829-3191
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Education & Training

Children's Hospital/Boston Medical CenterFellowship, Neonatal-Perinatal Medicine, 1997 - 2000
Children's Hospital/Boston Medical CenterResidency, Pediatrics, 1993 - 1996
Tufts University School of MedicineClass of 1993

Certifications & Licensure

MA State Medical License 1996 - 2025
PA State Medical License 2013 - 2024
American Board of Pediatrics Neonatal-Perinatal Medicine

Publications & Presentations

PubMed

Open-source code to extend early-onset sepsis calculator accessibility.
van der Weijden, B., Janssen, S., Plötz, F., Achten, N., Benitz, W., Kuzniewicz, M., Puopolo, K.> ;The Lancet. Digital Health. 2024 Mar 1
Antibiotic Use Among Infants Admitted to Neonatal Intensive Care Units.
Dustin D Flannery, Alvaro Zevallos Barboza, Sagori Mukhopadhyay, Kelly C Wade, Jeffrey S Gerber, Di Shu, Karen M Puopolo> ;JAMA Pediatrics. 2023 Dec 1
Association of delivery risk phenotype with early-onset sepsis in preterm infants.
Sarah A Coggins, Sagori Mukhopadhyay, Jourdan Triebwasser, Kevin J Downes, Jason D Christie, Karen M Puopolo> ;Journal of Perinatology. 2023 Sep 1
1 citations
Early antibiotic exposure in very-low birth weight infants and infection risk at 3-7 days after birth.
Sarah A Coggins, Zachary Willis, Daniel K Benjamin, Sagori Mukhopadhyay, Matthew Laughon, Rachel G Greenberg, Reese H Clark, Karen M Puopolo> ;Journal of Perinatology. 2023 Sep 1
1 citations
Measles Serostatus Among Parturient Patients at 2 Philadelphia Hospitals in 2021.
Dustin D Flannery, Alvaro Zevallos Barboza, Kelly C Wade, Madeline R Pfeifer, Jeffrey S Gerber, Jeffrey S Morris, Karen M Puopolo> ;JAMA. 2023 Feb 28
3 citations
Serratia Infection Epidemiology Among Very Preterm Infants in the Neonatal Intensive Care Unit.
Sarah A Coggins, Erika M Edwards, Dustin D Flannery, Jeffrey S Gerber, Jeffrey D Horbar, Karen M Puopolo> ;The Pediatric Infectious Disease Journal. 2023 Feb 1
4 citations
Diagnostic Performance and Patient Outcomes With C-Reactive Protein Use in Early-Onset Sepsis Evaluations.
Miren B Dhudasia, William E Benitz, Dustin D Flannery, Lori Christ, David Rub, Giulia Remaschi, Karen M Puopolo, Sagori Mukhopadhyay> ;The Journal of Pediatrics. 2023 May 1
9 citations
Neonatal Early-Onset Sepsis.
Dustin D Flannery, Karen M Puopolo> ;Neoreviews. 2022 Nov 1
10 citations
Comparison of Maternal and Neonatal Antibody Levels After COVID-19 Vaccination vs SARS-CoV-2 Infection.
Dustin D Flannery, Sigrid Gouma, Miren B Dhudasia, Sagori Mukhopadhyay, Madeline R Pfeifer, Emily C Woodford, Sara M Briker, Jourdan E Triebwasser, Jeffrey S Gerber, J...> ;JAMA Network Open. 2022 Nov 1
1 citations
Breast Milk and Saliva for Postnatal Cyto†megalovirus Screening among Very Low Birth Weight Infants.
Sagori Mukhopadhyay, Hannah L Itell, Erica Hartman, Emily Woodford, Miren B Dhudasia, Justin T Steppe, Sarah Valencia, Hunter Roark, Kelly C Wade, Kristin E D Weimer, ...> ;The Pediatric Infectious Disease Journal. 2022 Nov 1
5 citations
Perinatal COVID-19 maternal and neonatal outcomes at two academic birth hospitals.
Dustin D Flannery, Alvaro Zevallos Barboza, Madeline R Pfeifer, Mark L Hudak, Kimberly Barnette, Trace R Getzlaff, Sascha R Ellington, Kate R Woodworth, Miren B Dhudas...> ;Journal of Perinatology. 2022 Oct 1
Assessment of SARS-CoV-2 serostatus and hypertensive disorders of pregnancy.
Jourdan E Triebwasser, Miren B Dhudasia, Sagori Mukhopadhyay, Dustin D Flannery, Sigrid Gouma, Scott E Hensley, Karen M Puopolo> ;American Journal of Obstetrics and Gynecology. 2022 Oct 1
3 citations
Neonatal infections: Insights from a multicenter longitudinal research collaborative.
Dustin D Flannery, Karen M Puopolo, Nellie I Hansen, Pablo J Sánchez, Barbara J Stoll> ;Seminars in Perinatology. 2022 Nov 1
60 citations
Supplementation with a probiotic mixture accelerates gut microbiome maturation and reduces intestinal inflammation in extremely preterm infants.
Jumana Samara, Shirin Moossavi, Belal Alshaikh, Van A Ortega, Veronika Kuchařová Pettersen, Tahsin Ferdous, Suzie L Hoops, Amuchou Soraisham, Joseph Vayalumkal, Deonne...> ;Cell Host & Microbe. 2022 May 11
Early childhood antibiotic utilization for infants discharged from the neonatal intensive care unit.
Dustin D Flannery, Molly Passarella, Sagori Mukhopadhyay, Miren B Dhudasia, Jeffrey S Gerber, Scott A Lorch, Sean Hennessy, Karen M Puopolo> ;Journal of Perinatology. 2022 Jul 1
Promise and Risks of Newborn Mass Drug Administration.
Mukhopadhyay, S., Puopolo, K.> ;NEJM Evidence. 2022 Apr 1
1 citations
Group B Streptococcus Infection in Extremely Preterm Neonates and Neurodevelopmental Outcomes at 2 Years.
Karen M Puopolo, Sagori Mukhopadhyay, Nellie I Hansen, Dustin D Flannery, Rachel G Greenberg, Pablo J Sanchez, Edward F Bell, Sara B DeMauro, Myra H Wyckoff, Eric C Ei...> ;Clinical Infectious Diseases. 2022 Oct 12
8 citations
Time to positivity of blood cultures in neonatal late-onset bacteraemia.
Sagori Mukhopadhyay, Sara M Briker, Dustin D Flannery, Miren B Dhudasia, Sarah A Coggins, Emily Woodford, Eileen M Walsh, Sherian Li, Karen M Puopolo, Michael W Kuznie...> ;Archives of Disease in Childhood. Fetal and Neonatal Edition. 2022 Nov 1
3 citations
National Healthcare Safety Network 2018 Baseline Neonatal Standardized Antimicrobial Administration Ratios.
Erin N O'Leary, Jonathan R Edwards, Arjun Srinivasan, Melinda M Neuhauser, Minn M Soe, Amy K Webb, Erika M Edwards, Jeffrey D Horbar, Roger F Soll, Jessica Roberts, La...> ;Hospital Pediatrics. 2022 Feb 1
13 citations
Delivery Characteristics and the Risk of Early-Onset Neonatal Sepsis.
Dustin D Flannery, Sagori Mukhopadhyay, Knashawn H Morales, Miren B Dhudasia, Molly Passarella, Jeffrey S Gerber, Karen M Puopolo> ;Pediatrics. 2022 Feb 1
1 citations
Improving Compliance With Revised Newborn Hepatitis B Vaccination Policy.
Allene Pulsifer, Karen M. Puopolo, Miren B. Dhudasia, Beth Ann Pyle, Aida Schumacher, Sagori Mukhopadhyay> ;Hospital Pediatrics. 2021 Dec 1
9 citations
Antimicrobial Susceptibility Profiles Among Neonatal Early-onset Sepsis Pathogens.
Dustin D Flannery, Karen M. Puopolo, Nellie I. Hansen, Jeffrey S. Gerber, Pablo J. Sánchez, Barbara J. Stoll> ;The Pediatric Infectious Disease Journal. 2021 Nov 30
1 citations
The imperfect science of neonatal sepsis.
Dustin D. Flannery, Karen M. Puopolo> ;Pediatric Research. 2021 Nov 20
62 citations
Promoting Human Milk and Breastfeeding for the Very Low Birth Weight Infant.
Margaret G. Parker, Lisa M. Stellwagen, Lawrence Noble, Jae H. Kim, Brenda B. Poindexter, Karen M. Puopolo, Newborn> ;Pediatrics. 2021 Nov 1
21 citations
Neonatal multidrug-resistant gram-negative infection: epidemiology, mechanisms of resistance, and management.
Dustin D. Flannery, Kathleen Chiotos, Jeffrey S. Gerber, Karen M. Puopolo> ;Pediatric Research. 2021 Oct 1
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Lectures

Management of Infants at Risk for Group B Streptococcal Disease
National Conference & Exhibition 2019 - American Academy of Pediatrics - New Orleans, LA - 10/28/2019

Press Mentions

Researchers Analyze National Registry Data on Perinatal CovidJanuary 7th, 2023
Researchers Analyze National Registry Data on Perinatal CovidJanuary 6th, 2023
For Pregnant Women and Their Newborns, COVID Vaccine Offers Better Protection Than Prior InfectionNovember 10th, 2022
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Hospital Affiliations

Children's Hospital of PhiladelphiaPhiladelphia, Pennsylvania
Pennsylvania HospitalPhiladelphia, Pennsylvania