KarenCYoungMD

PubMed

• Pathogenesis and Physiologic Mechanisms of Neonatal Pulmonary Hypertension: Preclinical Studies.
  Karen C Young, Augusto F Schmidt, April W Tan, Lourenco Sbragia, Ahmed Elsaie, Binoy Shivanna> ;Clinics in Perinatology. 2024 Mar 1
• Chorioamnionitis accelerates granule cell and oligodendrocyte maturation in the cerebellum of preterm nonhuman primates.
  Newman, J., Tong, X., Tan, A., Yeasky, T., De Paiva, V., Presicce, P., Kannan, P., Williams, K., Damianos, A., Tamase Newsam, M., Benny, M., Wu, S., Young, K., Miller,...> ;Journal of Neuroinflammation. 2024 Jan 10
• GSDMD gene knockout alleviates hyperoxia-induced hippocampal brain injury in neonatal mice.
  Naga Venkata Divya Challa, Shaoyi Chen, Huijun Yuan, Matthew R Duncan, William Javier Moreno, Helen Bramlett, W Dalton Dietrich, Merline Benny, Augusto F Schmidt, Kare...> ;Journal of Neuroinflammation. 2023 Sep 7
• GSDMD gene knockout alleviates hyperoxia-induced hippocampal brain injury in neonatal mice.
  Naga Venkata Divya Challa, Shaoyi Chen, Huijun Yun, Matthew R Duncan, Williams Javier Moreno, Helen Bramlett, W Dalton Dietrich, Merline Benny, Augusto F Schmidt, Kare...> ;Research Square. 2023 Jun 15
• Stem cell regenerative therapies for neonatal diseases: Small steps, time to leap?
  Karen C Young> ;Seminars in Perinatology. 2023 Apr 1
• 4 citations
  GSDMD deficiency ameliorates hyperoxia-induced BPD and ROP in neonatal mice.
  Sarah Sonny, Huijun Yuan, Shaoyi Chen, Matthew R Duncan, Pingping Chen, Merline Benny, Karen Young, Kevin K Park, Augusto F Schmidt, Shu Wu> ;Scientific Reports. 2023 Jan 4
• c-Myc Drives inflammation of the maternal-fetal interface, and neonatal lung remodeling induced by intra-amniotic inflammation.
  April W Tan, Xiaoying Tong, Silvia Alvarez-Cubela, Pingping Chen, Aline Guimarães Santana, Alejo A Morales, Runxia Tian, Rae Infante, Vanessa Nunes de Paiva, Shathiyah...> ;Frontiers in Cell and Developmental Biology. 2023 Jan 1
• Case report: Fatal lung hyperinflammation in a preterm newborn with SARS-CoV-2 infection.
  Daniela Aguilar-Caballero, Jose M C Capcha, Veronica Caballero, Karen C Young, Shahnaz Duara, Michael Borchetta, Ivan Gonzalez, Ali G Saad, Keith A Webster, Lina A She...> ;Frontiers in Pediatrics. 2023 Jan 1
• 7 citations
  Systemic delivery of large-scale manufactured Wharton’s Jelly mesenchymal stem cell-derived extracellular vesicles improves cardiac function after myocardial infarction
  Michael A. Bellio, Rosemeire M. Kanashiro-Takeuchi, Lauro M Takeuchi, Shathiyah Kulandavelu, Yee-Shuan Lee, Wayne Balkan, Karen C. Young, Joshua M. Hare, Aisha Khan> ;The Journal of Cardiovascular Aging. 2022 Jan 1
• 1 citations
  Author Correction: Hyperoxia-activated circulating extracellular vesicles induce lung and brain injury in neonatal rats.
  Anum Ali, Ronald Zambrano, Matthew R. Duncan, Shaoyi Chen, Shihua Luo, Huijun Yuan, Pingping Chen, Augusto F. Schmidt, Karen Young, Nadine Kerr, Juan Pablo de Rivero V...> ;Scientific Reports. 2021 Oct 6
• 15 citations
  Amniotic fluid-derived extracellular vesicles: characterization and therapeutic efficacy in an experimental model of bronchopulmonary dysplasia
  Michael A. Bellio, Karen C. Young, Julian Milberg, Ivan Santos, Zanub Abdullah, Danique Stewart, Alissa Arango, Pingping Chen, Jian Huang, Kevin Williams, Kaitlyn Kell...> ;Cytotherapy. 2021 Sep 17
• 3 citations
  Placental dysfunction and impaired fetal growth: a relationship with bronchopulmonary dysplasia and pulmonary hypertension.
  Karen Young, Ilene R S Sosenko, Nelson Claure> ;Thorax. 2021 Aug 24
• 13 citations
  Hyperoxia-activated circulating extracellular vesicles induce lung and brain injury in neonatal rats
  Anum Ali, Ronald Zambrano, Matthew R. Duncan, Shaoyi Chen, Shihua Luo, Huijun Yuan, Pingping Chen, Augusto F. Schmidt, Karen Young, Nadine Kerr, Juan Pablo de Rivero V...> ;Scientific Reports. 2021 Apr 22
• 17 citations
  Soluble Klotho, a biomarker and therapeutic strategy to reduce bronchopulmonary dysplasia and pulmonary hypertension in preterm infants
  , , , , , , , , , , , , , , , , , , , > ;Scientific Reports. 2020 Jul 23
• 11 citations
  Effects of Klotho supplementation on hyperoxia-induced renal injury in a rodent model of postnatal nephrogenesis
  Mohammed Farhan Ali, Sunil Kumar Bathally Venkatarayappa, Claudia P. Rojas, Keyvan Yousefi, Lina A. Shehadeh, Shathiyah Kulandavelu, Mayank Sharma, Naimeh Da Silva, Mi...> ;Pediatric Research. 2020 Feb 14
• 10 citations
  Neonatal hyperoxia exposure induces aortic biomechanical alterations and cardiac dysfunction in juvenile rats.
  Diana R. Hernandez, Mayank Sharma, Keyvan Yousefi, Shathiyah Kulandavelu, Sunil Batlahally, Ronald Zambrano, Pingping Chen, Eliana C. Martinez, Augusto F. Schmidt, Lin...> ;Physiological Reports. 2020 Jan 1
• 4 citations
  Intra-tracheal administration of a naked plasmid expressing stromal derived factor-1 improves lung structure in rodents with experimental bronchopulmonary dysplasia
  Kasonya Guerra, Carleene Bryan, Frederick Dapaah-Siakwan, Ibrahim Sammour, Shelly Drummond, Ronald Zambrano, Pingping Chen, Jian Huang, Mayank Sharma, Sebastian Shrage...> ;Respiratory Research. 2019 Nov 12
• 30 citations
  Caspase-1 Inhibition Attenuates Hyperoxia-induced Lung and Brain Injury in Neonatal Mice.
  Fredrick Dapaah-Siakwan, Ronald Zambrano, Shihua Luo, Matthew R. Duncan, Nadine Kerr, Keyur Donda, Juan Pablo de Rivero Vaccari, Robert W. Keane, W. Dalton Dietrich, K...> ;American Journal of Respiratory Cell and Molecular Biology. 2019 Aug 30
• 14 citations
  TNFα-stimulated protein 6 (TSG-6) reduces lung inflammation in an experimental model of bronchopulmonary dysplasia.
  Carleene Bryan, Ibrahim Sammour, Kasonya Guerra, Mayank Sharma, Fredrick Dapaah-Siakwan, Jian Huang, Ronald Zambrano, Shu Wu, Karen Young> ;Pediatric Research. 2019 Feb 1
• 16 citations
  Riociguat prevents hyperoxia-induced lung injury and pulmonary hypertension in neonatal rats without effects on long bone growth.
  Keyur Donda, Ronald Zambrano, Younghye Moon, Justin M. Percival, Ruben Vaidya, Fredrick Dapaah-Siakwan, Shihua Luo, Matthew R. Duncan, Yong Bao, Luqing Wang, Ling Qin,...> ;Plos One. 2018 Jul 10
• Should All Extremely Premature Infants Be Screened for Pulmonary Hypertension
  Karen C. Young, Eduardo Bancalari> ;Neonatology. 2018 Jan 1
• 12 citations
  Intra-Amniotic Soluble Endoglin Impairs Lung Development in Neonatal Rats.
  Santhosh Somashekar, Ibrahim Sammour, Jian Huang, Juan Domínguez-Bendala, Ricardo L. Pastori, Silvia Álvarez-Cubela, Eneida Torres, Shu Wu, Karen C. Young> ;American Journal of Respiratory Cell and Molecular Biology. 2017 Sep 29
• 15 citations
  Recombinant CCN1 prevents hyperoxia-induced lung injury in neonatal rats.
  Ruben Vaidya, Ronald Zambrano, Julia K Hummler, Shihua Luo, Matthew R. Duncan, Karen Young, Lester F. Lau, Shu Wu> ;Pediatric Research. 2017 Aug 2
• 39 citations
  Stromal derived factor-1 mediates the lung regenerative effects of mesenchymal stem cells in a rodent model of bronchopulmonary dysplasia
  Joel Reiter, Shelley Drummond, Ibrahim Sammour, Jian Huang, Victoria Florea, Polliana Dornas, Joshua M. Hare, Claudia O. Rodrigues, Karen C. Young> ;Respiratory Research. 2017 Jul 12
• 22 citations
  Inhibition of Rac1 Signaling Downregulates Inflammasome Activation and Attenuates Lung Injury in Neonatal Rats Exposed to Hyperoxia.
  Julia K Hummler, Fredrick Dapaah-Siakwan, Ruben Vaidya, Ronald Zambrano, Siwei Luo, Shaoyi Chen, Nadine Kerr, Juan Pablo de Rivero Vaccari, Robert W. Keane, W. Dalton ...> ;Neonatology. 2017 Jan 1
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