KarnailSinghMD

PubMed

• 10 citations
  Parainfluenza Virus 5 Priming Followed by SIV/HIV Virus-Like-Particle Boosting Induces Potent and Durable Immune Responses in Nonhuman Primates.
  Peng Xiao, Krista Dienger-Stambaugh, Xuemin Chen, Huiling Wei, Shannon Phan, Ashley C. Beavis, Karnail Singh, Nihar R. Deb Adhikary, Pooja M. Tiwari, Francois Villinge...> ;Frontiers in Immunology. 2021 Feb 25
• 25 citations
  IL-2 enhances ex vivo-expanded regulatory T-cell persistence after adoptive transfer.
  Scott N. Furlan, Karnail Singh, Christina Lopez, Victor Tkachev, Daniel J. Hunt, James Hibbard, Kayla Betz, Bruce R. Blazar, Cole Trapnell, Leslie S. Kean> ;Blood Advances. 2020 Apr 28
• 13 citations
  A Bivalent, Spherical Virus-Like Particle Vaccine Enhances Breadth of Immune Responses against Pathogenic Ebola Viruses in Rhesus Macaques.
  Karnail Singh, Bishal Marasini, Xuemin Chen, Lingmei Ding, Jaang-Jiun Wang, Peng Xiao, Paul Spearman> ;Journal of Virology. 2020 Apr 16
• 7 citations
  A novel Ebola virus antibody-dependent cell-mediated cytotoxicity (Ebola ADCC) assay.
  Karnail Singh, Bishal Marasini, Paul Spearman> ;Journal of Immunological Methods. 2018 Sep 1
• 20 citations
  The Knife’s Edge of Tolerance: Inducing Stable Multilineage Mixed Chimerism but With a Significant Risk of CMV Reactivation and Disease in Rhesus Macaques
  Hengqi Zheng, Benjamin Watkins, Victor Tkachev, Shan Yu, Dollnovan Tran, Scott N. Furlan, Katie Zeleski, Karnail Singh, Kelly Hamby, Charlotte E. Hotchkiss, Jennifer L...> ;American Journal of Transplantation. 2017 Mar 1
• 2 citations
  Preclinical Testing of Antihuman CD28 Fab' Antibody in a Novel Nonhuman Primate Small Animal Rodent Model of Xenogenic Graft-Versus-Host Disease.
  Keli L Hippen, Benjamin Watkins, Victor Tkachev, Amanda M Lemire, Charles Lehnen, Megan J Riddle, Karnail Singh, Angela Panoskaltsis-Mortari, Bernard Vanhove, Jakub To...> ;Transplantation. 2016 Dec 1
• 7 citations
  A phase 1, randomized, controlled dose-escalation study of EP-1300 polyepitope DNA vaccine against Plasmodium falciparum malaria administered via electroporation.
  Paul Spearman, Mark J. Mulligan, Evan J. Anderson, Andi L. Shane, Kathy Stephens, Theda Gibson, Brooke Hartwell, Drew Hannaman, Nora L. Watson, Karnail Singh> ;Vaccine. 2016 Nov 4
• 44 citations
  Transcriptome analysis of GVHD reveals aurora kinase A as a targetable pathway for disease prevention
  Scott N. Furlan, Benjamin Watkins, Victor Tkachev, Ryan Flynn, Sarah Cooley, Swetha Ramakrishnan, Karnail Singh, Cynthia R. Giver, Kelly Hamby, Linda Stempora, Aneesah...> ;Science Translational Medicine. 2015 Nov 25
• 35 citations
  Bone loss in surgically ovariectomized premenopausal women is associated with T lymphocyte activation and thymic hypertrophy.
  Saira Adeel, Karnail Singh, Kay H. Vydareny, Meena Kumari, Era Shah, Mervyn Neale Weitzmann, Vin Tangpricha> ;Journal of Investigative Medicine. 2013 Dec 1
• 67 citations
  IL-7– and IL-15–Mediated TCR Sensitization Enables T Cell Responses to Self-Antigens
  Pratima Deshpande, Mary M. Cavanagh, Sabine Le Saux, Karnail Singh, Cornelia M. Weyand, Jörg J. Goronzy> ;Journal of Immunology. 2013 Feb 15
• 3 citations
  Viewing transplantation immunology through today's lens: new models, new imaging, and new insights.
  Alex Yee-Chen Huang, W. Nicholas Haining, Deborah S. Barkauskas, Jay Myers, Agne Petrosiute, Aneesah Garrett, Karnail Singh, Kenneth R. Cooke, Leslie S. Kean> ;Biology of Blood and Marrow Transplantation. 2013 Jan 1
• 17 citations
  Evidence for kidney rejection after combined bone marrow and renal transplantation despite ongoing whole-blood chimerism in rhesus macaques.
  Swetha Ramakrishnan, Andrew J. Page, Alton B. Farris, Karnail Singh, F. Leopardi, Kelly Hamby, Sharon Sen, Aneesah Polnett, Taylor Deane, M. Song, Linda Stempora, Eliz...> ;American Journal of Transplantation. 2012 Jul 1
• 25 citations
  K-RAS GTPase- and B-RAF kinase-mediated T-cell tolerance defects in rheumatoid arthritis
  Karnail Singh, Pratima Deshpande, Guangjin Li, Mingcan Yu, Sergey Pryshchep, Mary M. Cavanagh, Cornelia M. Weyand, Jörg J. Goronzy> ;Proceedings of the National Academy of Sciences of the United States of America. 2012 Jun 19
• 43 citations
  Regulatory T Cells Exhibit Decreased Proliferation but Enhanced Suppression After Pulsing With Sirolimus
  Karnail Singh, Natalia Kozyr, Linda Stempora, Allan D. Kirk, Christian P. Larsen, Bruce R. Blazar, Leslie S. Kean> ;American Journal of Transplantation. 2012 Jun 1
• 23 citations
  Nonhuman Primate Transplant Models Finally Evolve: Detailed Immunogenetic Analysis Creates New Models and Strengthens the Old
  Leslie S. Kean, Karnail Singh, Bruce R. Blazar, Christian P. Larsen> ;American Journal of Transplantation. 2012 Apr 1
• 49 citations
  CD40 Blockade Combines with CTLA4Ig and Sirolimus to Produce Mixed Chimerism in an MHC‐Defined Rhesus Macaque Transplant Model
  Andrew J. Page, Swetha Srinivasan, Karnail Singh, Maria C. Russell, Kelly Hamby, Taylor Deane, Sharon Sen, Linda Stempora, F. Leopardi, Andrew A. Price, Elizabeth Stro...> ;American Journal of Transplantation. 2012 Jan 1
• 59 citations
  Significant mobilization of both conventional and regulatory T cells with AMD3100
  Leslie S. Kean, Sharon Sen, Olusegun O. Onabajo, Karnail Singh, Jennifer Robertson, Linda Stempora, Aylin C. Bonifacino, Mark E. Metzger, Daniel E. L. Promislow, Josep...> ;Blood. 2011 Dec 15
• 99 citations
  Regulation of T cell receptor signaling by activation-induced zinc influx
  Mingcan Yu, Won Woo Lee, Deepak Tomar, Sergey Pryshchep, Marta Czesnikiewicz-Guzik, David L. Lamar, Guangjin Li, Karnail Singh, Lu Tian, Cornelia M. Weyand, Jörg J. Go...> ;The Journal of Experimental Medicine. 2011 Apr 11
• 16 citations
  Polypyrimidine Tract-Binding Protein Is Critical for the Turnover and Subcellular Distribution of CD40 Ligand mRNA in CD4+ T Cells
  Rodrigo Matus-Nicodemos, Stefano Vavassori, Moraima Castro-Faix, Anibal Valentin-Acevedo, Karnail Singh, Valentina Marcelli, Lori R. Covey> ;Journal of Immunology. 2011 Feb 15
• 60 citations
  GVHD after haploidentical transplantation: a novel, MHC-defined rhesus macaque model identifies CD28- CD8+ T cells as a reservoir of breakthrough T-cell proliferation ...
  Weston P. Miller, Swetha Srinivasan, Angela Panoskaltsis-Mortari, Karnail Singh, Sharon Sen, Kelly Hamby, Taylor Deane, Linda Stempora, Jonathan Beus, AP Turner, Caleb...> ;Blood. 2010 Dec 9
• 45 citations
  An MHC-defined primate model reveals significant rejection of bone marrow after mixed-chimerism induction despite full MHC matching
  Christian P. Larsen, Andrew J. Page, Kelly Hamby Linzie, Maria C. Russell, Taylor Deane, Linda Stempora, Elizabeth Strobert, Maria Cecilia T. Penedo, Thea Ward, Roger ...> ;American Journal of Transplantation. 2010 Nov 1
• 61 citations
  ERK-dependent T-cell receptor threshold calibration in rheumatoid arthritis
  Karnail Singh, Pratima Deshpande, Sergey Pryshchep, Ines Colmegna, Vladimir M. Liarski, Cornelia M. Weyand, Jörg J. Goronzy> ;Journal of Immunology. 2009 Dec 15
• 27 citations
  TLR-mediated induction of negative regulatory ligands on dendritic cells
  Stefan Gröschel, Kisha Piggott, Augusto Vaglio, Wei Ma-Krupa, Karnail Singh, Jörg J. Goronzy, Cornelia M. Weyand> ;Journal of Molecular Medicine. 2008 Feb 6
• 28 citations
  Synoviocyte Stimulation by the LFA-1–Intercellular Adhesion Molecule-2–Ezrin–Akt Pathway in Rheumatoid Arthritis
  Karnail Singh, Ines Colmegna, Xiaowen He, Cornelia M. Weyand, Jörg J. Goronzy> ;Journal of Immunology. 2008 Feb 1
• 48 citations
  Uncoupling of T-cell effector functions by inhibitory killer immunoglobulin-like receptors
  Gabriella Henel, Karnail Singh, Dapeng Cui, Sergey Pryshchep, Won Woo Lee, Cornelia M. Weyand, Jörg J. Goronzy> ;Blood. 2006 Jun 1
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